RETROFIT is a Bayesian non-negative matrix factorization framework to decompose cell type mixtures in ST data without using external single-cell expression references. RETROFIT outperforms existing reference-based methods in estimating cell type proportions and reconstructing gene expressions in simulations with varying spot size and sample heterogeneity, irrespective of the quality or availability of the single-cell reference. RETROFIT recapitulates known cell-type localization patterns in a Slide-seq dataset of mouse cerebellum without using any single-cell data.
The SPRITE algorithm creates possible distributions of discrete responses based on reported sample parameters, such as mean, standard deviation and range (Heathers et al., 2018, <doi:10.7287/peerj.preprints.26968v1>). This package implements it, drawing heavily on the code for Nick Brown's rSPRITE Shiny app <https://shiny.ieis.tue.nl/sprite/>. In addition, it supports the modeling of distributions based on multi-item (Likert-type) scales and the use of restrictions on the frequency of particular responses.
The basic algorithm to perform the folding test of unimodality. Given a dataset X (d dimensional, n samples), the test checks whether the distribution of the data are rather unimodal or rather multimodal. This package stems from the following research publication: Siffer Alban, Pierre-Alain Fouque, Alexandre Termier, and Christine Largouët. "Are your data gathered?" In Proceedings of the 24th ACM SIGKDD International Conference on Knowledge Discovery Data Mining, pp. 2210-2218. ACM, 2018. <doi:10.1145/3219819.3219994>.
F-informed MDS is a new multidimensional scaling-based ordination method that configures data distribution based on the F-statistic (i.e., the ratio of dispersion between groups with shared or differing labels).
This package provides tools to analyze alternative splicing sites, interpret outcomes based on sequence information, select and design primers for site validiation and give visual representation of the event to guide downstream experiments.
This package contains a set of functions to perform large-scale analysis of toxicogenomic data, providing a standardized data structure to hold information relevant to annotation, visualization and statistical analysis of toxicogenomic data.
The package allows users to readily import spatial data obtained from the 10X Xenium Analyzer pipeline. Supported formats include parquet', h5', and mtx files. The package mainly represents data as SpatialExperiment objects.
Parsing R code is key to build tools such as linters and stylers. This package provides a binding to the Rust crate ast-grep so that one can parse and explore R code.
Tree- and rule-based models can be bagged (<doi:10.1007/BF00058655>) using this package and their predictions equations are stored in an efficient format to reduce the model objects size and speed.
This package provides functions to compute pair-wise dissimilarities (distance matrices) and multiple-site dissimilarities, separating the turnover and nestedness-resultant components of taxonomic (incidence and abundance based), functional and phylogenetic beta diversity.
The cystiSim package provides an agent-based model for Taenia solium transmission and control. cystiSim was developed within the framework of CYSTINET, the European Network on taeniosis/cysticercosis, COST ACTION TD1302.
The Codemeta Project defines a JSON-LD format for describing software metadata, as detailed at <https://codemeta.github.io>. This package provides core utilities to generate this metadata with a minimum of dependencies.
This package provides a drop-in replacement for dplyr', powered by DuckDB for performance. Offers convenient utilities for working with in-memory and larger-than-memory data while retaining full dplyr compatibility.
Gas/Liquid Chromatography-Mass Spectrometer(GC/LC-MS) Data Analysis for Environmental Science. This package covered topics such molecular isotope ratio, matrix effects and Short-Chain Chlorinated Paraffins analysis etc. in environmental analysis.
Checks to see whether a supplied set of dice (their face values) are transitive, returning pair-win and group-roll win probabilities. Expected returns (mean magnitude of win/loss) are presented as well.
Convenient classes to model fitness landscapes and fitness seascapes. A low-level package with which most users will not interact but upon which other packages modeling fitness landscapes and fitness seascapes will depend.
Growth models and forest production require existing data manipulation and the creation of new data, structured from basic forest inventory data. The purpose of this package is provide functions to support these activities.
An interface for retrieving and displaying the information returned online by Google Trends is provided. Trends (number of hits) over the time as well as geographic representation of the results can be displayed.
This package provides tools for accessing various open data APIs in the Helsinki region in Finland. Current data sources include the Service Map API, Linked Events API, and Helsinki Region Infoshare statistics API.
Harriet was Charles Darwin's pet tortoise (possibly). harrietr implements some function to manipulate distance matrices and phylogenetic trees to make it easier to plot with ggplot2 and to manipulate using tidyverse tools.
This package provides a collection of functions for sampling and simulating 3D surfaces and objects and estimating metrics like rugosity, fractal dimension, convexity, sphericity, circularity, second moments of area and volume, and more.
An interactive document on the topic of K-nearest neighbour (KNN) using rmarkdown and shiny packages. Runtime examples are provided in the package function as well as at <https://kartikeyabolar.shinyapps.io/KNNShiny/>.
This package implements two versions of the algorithm namely: stochastic and batch. The package determines also the best number of clusters and offers to the user the best clustering scheme from different results.
Get map data frames for the Indian subcontinent with different region levels (e.g., district, state). The package also offers convenience functions for plotting choropleths, visualizing spatial data, and handling state/district codes.