Allow R users to interact with the Canvas Learning Management System (LMS) API (see <https://canvas.instructure.com/doc/api/all_resources.html> for details). It provides a set of functions to access and manipulate course data, assignments, grades, users, and other resources available through the Canvas API.

The fishpond package contains methods for differential transcript and gene expression analysis of RNA-seq data using inferential replicates for uncertainty of abundance quantification, as generated by Gibbs sampling or bootstrap sampling. Also the package contains a number of utilities for working with Salmon and Alevin quantification files.

This package provides a enhanced visualization of single-cell data based on gene-weighted density estimation. Nebulosa recovers the signal from dropped-out features and allows the inspection of the joint expression from multiple features (e.g. genes). Seurat and SingleCellExperiment objects can be used within Nebulosa.

MultiBaC is a strategy to correct batch effects from multiomic datasets distributed across different labs or data acquisition events. MultiBaC is able to remove batch effects across different omics generated within separate batches provided that at least one common omic data type is included in all the batches considered.

This package provides well-known outlier detection techniques in the univariate case. Methods to deal with skewed distribution are included too. The Hidiroglou-Berthelot (1986) method to search for outliers in ratios of historical data is implemented as well. When available, survey weights can be used in outliers detection.

This package provides functions for Meta-analysis Burden Test, Sequence Kernel Association Test (SKAT) and Optimal SKAT (SKAT-O) by Lee et al. (2013) <doi:10.1016/j.ajhg.2013.05.010>. These methods use summary-level score statistics to carry out gene-based meta-analysis for rare variants.

This package provides a set of tools for post processing the outcomes of species distribution modeling exercises. It includes novel methods for comparing models and tracking changes in distributions through time. It further includes methods for visualizing outcomes, selecting thresholds, calculating measures of accuracy and landscape fragmentation statistics, etc.

This package provides extra themes and scales for ggplot2 that replicate the look of plots by Edward Tufte and Stephen Few in Fivethirtyeight, The Economist, Stata, Excel, and The Wall Street Journal, among others. This package also provides geoms for Tufte's box plot and range frame.

This package provides an R interface to the dygraphs JavaScript charting library (a copy of which is included in the package). It provides rich facilities for charting time-series data in R, including highly configurable series- and axis-display and interactive features like zoom/pan and series/point highlighting.

This package computes fast (relative to other implementations) approximate Shapley values for any supervised learning model. Shapley values help to explain the predictions from any black box model using ideas from game theory; see doi.org/10.1007/s10115-013-0679-x for details.

We perform linear, logistic, and cox regression using the base functions lm(), glm(), and coxph() in the R software and the survival package. Likewise, we can use ols(), lrm() and cph() from the rms package for the same functionality. Each of these two sets of commands has a different focus. In many cases, we need to use both sets of commands in the same situation, e.g. we need to filter the full subset model using AIC, and we need to build a visualization graph for the final model. base.rms package can help you to switch between the two sets of commands easily.

Three robust marginal integration procedures for additive models based on local polynomial kernel smoothers. As a preliminary estimator of the multivariate function for the marginal integration procedure, a first approach uses local constant M-estimators, a second one uses local polynomials of order 1 over all the components of covariates, and the third one uses M-estimators based on local polynomials but only in the direction of interest. For this last approach, estimators of the derivatives of the additive functions can be obtained. All three procedures can compute predictions for points outside the training set if desired. See Boente and Martinez (2017) <doi:10.1007/s11749-016-0508-0> for details.

Model based simulation of dynamic networks under tie-oriented (Butts, C., 2008, <doi:10.1111/j.1467-9531.2008.00203.x>) and actor-oriented (Stadtfeld, C., & Block, P., 2017, <doi:10.15195/v4.a14>) relational event models. Supports simulation from a variety of relational event model extensions, including temporal variability in effects, heterogeneity through dyadic latent class relational event models (DLC-REM), random effects, blockmodels, and memory decay in relational event models (Lakdawala, R., 2024 <doi:10.48550/arXiv.2403.19329>). The development of this package was supported by a Vidi Grant (452-17-006) awarded by the Netherlands Organization for Scientific Research (NWO) Grant and an ERC Starting Grant (758791).

This package provides functions for interacting directly with the ALTADATA API. With this R package, developers can build applications around the ALTADATA API without having to deal with accessing and managing requests and responses. ALTADATA is a curated data marketplace for more information go to <https://www.altadata.io>.

Fit Generalized Additive Models (GAM) using mgcv with parsnip'/'tidymodels via additive <doi:10.5281/zenodo.4784245>. tidymodels is a collection of packages for machine learning; see Kuhn and Wickham (2020) <https://www.tidymodels.org>). The technical details of mgcv are described in Wood (2017) <doi:10.1201/9781315370279>.

Computation of large covariance matrices having a block structure up to a permutation of their columns and rows from a small number of samples with respect to the dimension of the matrix. The method is described in the paper Perrot-Dockès et al. (2019) <arXiv:1806.10093>.

Cleaning and standardizing tabular data package, tailored specifically for curating epidemiological data. It streamlines various data cleaning tasks that are typically expected when working with datasets in epidemiology. It returns the processed data in the same format, and generates a comprehensive report detailing the outcomes of each cleaning task.

Wraps cytoscape.js as a shiny widget. cytoscape.js <https://js.cytoscape.org/> is a Javascript-based graph theory (network) library for visualization and analysis. This package supports the visualization of networks with custom visual styles and several available layouts. Demo Shiny applications are provided in the package code.

Estimation of sparse nonlinear functions in nonparametric regression using component selection and smoothing. Designed for the analysis of high-dimensional data, the models support various data types, including exponential family models and Cox proportional hazards models. The methodology is based on Lin and Zhang (2006) <doi:10.1214/009053606000000722>.

Utility functions that allow checking the basic validity of a function argument or any other value, including generating an error and assigning a default in a single line of code. The main purpose of the package is to provide simple and easily readable argument checking to improve code robustness.

Data are essential in statistical analysis. This data package consists of four datasets for descriptive statistics, two datasets for statistical hypothesis testing, and two datasets for regression analysis. All of the datasets are based on Rattanalertnusorn, A. (2024) <https://www.researchgate.net/publication/371944275_porkaermxarlaeakarprayuktchingan_R_and_its_applications>.

For estimation of a variable of interest using Kalman filter by incorporating results from previous assessments, i.e. through development weighted estimates where weights are assigned inversely proportional to the variance of existing and new estimates. For reference see Ehlers et al. (2017) <doi:10.20944/preprints201710.0098.v1>.

Supports the process of applying a cut to Standard Data Tabulation Model (SDTM), as part of the analysis of specific points in time of the data, normally as part of investigation into clinical trials. The functions support different approaches of cutting to the different domains of SDTM normally observed.

Inspect survival data, plot Kaplan-Meier curves, assess the proportional hazards assumption, fit parametric survival models, predict and plot survival and hazards, and export the outputs to Excel. A simple interface for fitting survival models using flexsurv::flexsurvreg()', flexsurv::flexsurvspline()', flexsurvcure::flexsurvcure()', and survival::survreg()'.