This package provides functions for Meta-analysis Burden Test, Sequence Kernel Association Test (SKAT) and Optimal SKAT (SKAT-O) by Lee et al. (2013) <doi:10.1016/j.ajhg.2013.05.010>. These methods use summary-level score statistics to carry out gene-based meta-analysis for rare variants.

This package provides well-known outlier detection techniques in the univariate case. Methods to deal with skewed distribution are included too. The Hidiroglou-Berthelot (1986) method to search for outliers in ratios of historical data is implemented as well. When available, survey weights can be used in outliers detection.

This package computes fast (relative to other implementations) approximate Shapley values for any supervised learning model. Shapley values help to explain the predictions from any black box model using ideas from game theory; see doi.org/10.1007/s10115-013-0679-x for details.

Data driven strategy to find hidden groups of patients with complex diseases using clinical data. ClustAll facilitates the unsupervised identification of multiple robust stratifications. ClustAll, is able to overcome the most common limitations found when dealing with clinical data (missing values, correlated data, mixed data types).

HMP2Data is a Bioconductor package of the Human Microbiome Project 2 (HMP2) 16S rRNA sequencing data. Processed data is provided as phyloseq, SummarizedExperiment, and MultiAssayExperiment class objects. Individual matrices and data.frames used for building these S4 class objects are also provided in the package.

svaRetro contains functions for detecting retrotransposed transcripts (RTs) from structural variant calls. It takes structural variant calls in GRanges of breakend notation and identifies RTs by exon-exon junctions and insertion sites. The candidate RTs are reported by events and annotated with information of the inserted transcripts.

`tomoseqr` is an R package for analyzing Tomo-seq data. Tomo-seq is a genome-wide RNA tomography method that combines combining high-throughput RNA sequencing with cryosectioning for spatially resolved transcriptomics. `tomoseqr` reconstructs 3D expression patterns from tomo-seq data and visualizes the reconstructed 3D expression patterns.

This package provides methods for analyzing DNA copy-number data. Specifically, this package implements the multi-source copy-number normalization (MSCN) method for normalizing copy-number data obtained on various platforms and technologies. It also implements the TumorBoost method for normalizing paired tumor-normal SNP data.

Utility functions, datasets and extended examples for survival analysis. This extends a range of other packages, some simple wrappers for time-to-event analyses, datasets, and extensive examples in HTML with R scripts. The package also supports the course Biostatistics III entitled "Survival analysis for epidemiologists in R".

An R interface for the Brown Dog which allows researchers to leverage Brown Dog Services that provides modules to identify the conversion options for a file, to convert file to appropriate format, or to extract data from a file. See <http://browndog.ncsa.illinois.edu/> for more information.

Helps automate Quarto website creation for small academic groups. Builds a database-like structure of people, projects and publications, linking them together with a string-based ID system. Then, provides functions to automate production of clean markdown for these structures, and in-built CSS formatting using CSS flexbox.

This package performs Correlated Meta-Analysis ('corrmeta') across multiple OMIC scans, accounting for hidden non-independencies between elements of the scans due to overlapping samples, related samples, or other information. For more information about the method, refer to the paper Province MA. (2013) <doi:10.1142/9789814447973_0023>.

This package provides friendly wrappers for creating duckdb'-backed connections to tabular datasets ('csv', parquet, etc) on local or remote file systems. This mimics the behaviour of "open_dataset" in the arrow package, but in addition to S3 file system also generalizes to any list of http URLs.

This package implements stochastic simulations of community assembly (ecological diversification) using customizable ecospace frameworks (functional trait spaces). Provides a wrapper to calculate common ecological disparity and functional ecology statistical dynamics as a function of species richness. Functions are written so they will work in a parallel-computing environment.

An RStudio addin for editing a data.frame or a tibble'. You can delete, add or update a data.frame without coding. You can get resultant data as a data.frame'. In the package, modularized shiny app codes are provided. These modules are intended for reuse across applications.

This package provides a collection of curated educational datasets for teaching ecology and agriculture concepts. Includes data on wildlife monitoring, plant treatments, and ecological observations with documentation and examples for educational use. All datasets are derived from published scientific studies and are available under CC0 or compatible licenses.

This package provides a tool for conducting exact parametric regression-based causal mediation analysis of binary outcomes as described in Samoilenko, Blais and Lefebvre (2018) <doi:10.1353/obs.2018.0013>; Samoilenko, Lefebvre (2021) <doi:10.1093/aje/kwab055>; and Samoilenko, Lefebvre (2023) <doi:10.1002/sim.9621>.

Simplifies some complicated and labor intensive processes involved in exploring and explaining data. Allows you to quickly and efficiently visualize the interaction between variables and simplifies the process of discovering covariation in your data. Also includes some convenience features designed to remove as much redundant typing as possible.

Computes the expectation of the number of transmissions and receptions considering an End-to-End transport model with limited number of retransmissions per packet. It provides theoretical results and also estimated values based on Monte Carlo simulations. It is also possible to consider random data and ACK probabilities.

Optimal experimental designs for functional linear and functional generalised linear models, for scalar responses and profile/dynamic factors. The designs are optimised using the coordinate exchange algorithm. The methods are discussed by Michaelides (2023) <https://eprints.soton.ac.uk/474982/1/Thesis_DamianosMichaelides_Final_pdfa_1_.pdf>.

This package provides a set of helper functions for constructing file paths relative to the root of various types of projects, such as R packages, Git repositories, and more. File paths are specified with function arguments, or `$` to navigate into folders to specific files supported by auto-completion.

An R interface to the GPTZero API (<https://gptzero.me/docs>). Allows users to classify text into human and computer written with probabilities. Formats the data into data frames where each sentence is an observation. Paragraph-level and document-level predictions are organized to align with the sentences.

This package provides features for searching, converting, analyzing, plotting, and exporting data effortlessly by inputting feature IDs. Enables easy retrieval of feature information, conversion of ID types, gene enrichment analysis, publication-level figures, group interaction plotting, and result export in one Excel file for seamless sharing and communication.

Facilitates fitting measurement error and missing data imputation models using integrated nested Laplace approximations, according to the method described in Skarstein, Martino and Muff (2023) <doi:10.1002/bimj.202300078>. See Skarstein and Muff (2024) <doi:10.48550/arXiv.2406.08172> for details on using the package.