This package provides tools to import transcript-level abundance, estimated counts and transcript lengths, and to summarize them into matrices for use with downstream gene-level analysis packages. Average transcript length, weighted by sample-specific transcript abundance estimates, is provided as a matrix which can be used as an offset for different expression of gene-level counts.

This package contains methods for converting standard objects constructed by bioinformatics packages, especially those in Bioconductor, and converting them to tidy data. It thus serves as a complement to the broom package, and follows the same tidy, augment, glance division of tidying methods. Tidying data makes it easy to recombine, reshape and visualize bioinformatics analyses.

This package aims to bring the power and flexibility of AnnData to the R ecosystem, allowing you to effortlessly manipulate and analyze your single-cell data. This package lets you work with backed h5ad and zarr files, directly access various slots (e.g. X, obs, var), or convert the data into SingleCellExperiment and Seurat objects.

This package provides flexible parametric models for time-to-event data, including the Royston-Parmar spline model, generalized gamma and generalized F distributions. Any user-defined parametric distribution can be fitted, given at least an R function defining the probability density or hazard. There are also tools for fitting and predicting from fully parametric multi-state models.

Tool to help debug / hack at the BCM283x GPIO. You can dump the state of a GPIO (or all GPIOs). You can change a GPIO mode and pulls (and level, if set as an output). Beware that this tool writes directly to the BCM283x GPIO registers, ignoring anything else that may be using them (like Linux drivers).

Open Cancer TherApeutic Discovery (OCTAD) package implies sRGES approach for the drug discovery. The essential idea is to identify drugs that reverse the gene expression signature of a disease by tamping down over-expressed genes and stimulating weakly expressed ones. The following package contains all required precomputed data for whole OCTAD pipeline computation.

This contains helpful functions for parsing, managing, plotting, and visualizing activities, most often from GPX (GPS Exchange Format) files recorded by GPS devices. It allows easy parsing of the source files into standard R data formats, along with functions to compute derived data for the activity, and to plot the activity in a variety of ways.

Animation of observed trajectories using spline-based interpolation (see for example, Buderman, F. E., Hooten, M. B., Ivan, J. S. and Shenk, T. M. (2016), <doi:10.1111/2041-210X.12465> "A functional model for characterizing long-distance movement behaviour". Methods Ecol Evol). Intended to be used exploratory data analysis, and perhaps for preparation of presentations.

Multivariate tools to analyze comparative data, i.e. a phylogeny and some traits measured for each taxa. The package contains functions to represent comparative data, compute phylogenetic proximities, perform multivariate analysis with phylogenetic constraints and test for the presence of phylogenetic autocorrelation. The package is described in Jombart et al (2010) <doi:10.1093/bioinformatics/btq292>.

This package provides tools to generate unique identifier codes and printable barcoded labels for the management of biological samples. The creation of unique ID codes and printable PDF files can be initiated by standard commands, user prompts, or through a GUI addin for R Studio. Biologically informative codes can be included for hierarchically structured sampling designs.

This package provides similar functionality to Microsoft Excel CUMPRINC function <https://support.microsoft.com/en-us/office/cumprinc-function-94a4516d-bd65-41a1-bc16-053a6af4c04d>. Returns principal remaining at a given month, principal paid in a month, and accumulated principal paid at a given month based on original loan amount, monthly interest rate, and term of loan.

Tests whether multivariate ordinal data may stem from discretizing a multivariate normal distribution. The test is described by Foldnes and Grønneberg (2019) <doi:10.1080/10705511.2019.1673168>. In addition, an adjusted polychoric correlation estimator is provided that takes marginal knowledge into account, as described by Grønneberg and Foldnes (2022) <doi:10.1037/met0000495>.

Fast procedures for small set of commonly-used, design-appropriate estimators with robust standard errors and confidence intervals. Includes estimators for linear regression, instrumental variables regression, difference-in-means, Horvitz-Thompson estimation, and regression improving precision of experimental estimates by interacting treatment with centered pre-treatment covariates introduced by Lin (2013) <doi:10.1214/12-AOAS583>.

This package provides a collection of utility functions for manipulating and analyzing factor vectors in R. It offers tools for filtering, splitting, combining, and reordering factor levels based on various criteria. The package is designed to simplify common tasks in categorical data analysis, making it easier to work with factors in a flexible and efficient manner.

This package provides a voxel is a representation of a value on a regular, three-dimensional grid; it is the 3D equivalent of a 2D pixel. Voxel data can be visualised with this package using fixed viewpoint isometric cubes for each data point. This package also provides sample voxel data and tools for transforming the data.

This package provides an interface to the financial data platform <https://datahub.limex.com/>., enabling users to retrieve real-time and historical financial data. Functions within the package allow access to instruments, candlestick charts, fundamentals, news, events, models, and trading signals. Authentication is managed through user-specific API tokens, which are securely handled via environment variables.

Simulate, manage, visualize, and analyze spatially and temporally explicit datasets of mating potential. Implements methods to calculate synchrony, proximity, and compatibility.Synchrony calculations are based on methods described in Augspurger (1983) <doi:10.2307/2387650>, Kempenaers (1993) <doi:10.2307/3676415>, Ison et al. (2014) <doi:10.3732/ajb.1300065>, and variations on these, as described.

This package provides methods for extracting results from mixed-effect model objects fit with the lme4 package. Allows construction of prediction intervals efficiently from large scale linear and generalized linear mixed-effects models. This method draws from the simulation framework used in the Gelman and Hill (2007) textbook: Data Analysis Using Regression and Multilevel/Hierarchical Models.

Given a data matrix with rows representing data vectors and columns representing variables, produces a directed polytree for the underlying causal structure. Based on the algorithm developed in Chatterjee and Vidyasagar (2022) <arxiv:2209.07028>. The method is fully nonparametric, making no use of linearity assumptions, and especially useful when the number of variables is large.

This package contains a graphical user interface to generate the diagnostic plots proposed by Bauer (2005; <doi:10.1207/s15328007sem1204_1>), Pek & Chalmers (2015; <doi:10.1080/10705511.2014.937790>), and Pek, Chalmers, R. Kok, & Losardo (2015; <doi:10.3102/1076998615589129>) to investigate nonlinear bivariate relationships in latent regression models using structural equation mixture models (SEMMs).

This package provides a no-frills open-source solution for designing plot labels affixed with QR codes. It features EasyQrlabelr', a BrAPI-compliant shiny app that simplifies the process of plot label design for non-R users. It builds on the methods described by Wu et al. (2020) <doi:10.1111/2041-210X.13405>.

An implementation of sensitivity analysis for phylogenetic comparative methods. The package is an umbrella of statistical and graphical methods that estimate and report different types of uncertainty in PCM: (i) Species Sampling uncertainty (sample size; influential species and clades). (ii) Phylogenetic uncertainty (different topologies and/or branch lengths). (iii) Data uncertainty (intraspecific variation and measurement error).

Generate knockoffs for genetic data and hidden Markov models. For more information, see the website below and the accompanying papers: "Gene hunting with hidden Markov model knockoffs", Sesia et al., Biometrika, 2019, (<doi:10.1093/biomet/asy033>). "Multi-resolution localization of causal variants across the genome", Sesia et al., bioRxiv, 2019, (<doi:10.1101/631390>).

This package provides a tool for bootstrapping new packages with useful defaults, including a test suite outline that passes checks and helpers for running tests, checking test coverage, building vignettes, and more. Package skeletons it creates are set up for pushing your package to GitHub and using other hosted services for building and test automation.