This package provides a unified framework for optimizing basket trial designs. To this end, the package supplies several utility functions and also a function for executing optimization algorithms on basket trial designs. The considered utility functions are discussed in Sauer et al. (2025) <doi:10.1371/journal.pone.0323097>.

Computation of large covariance matrices having a block structure up to a permutation of their columns and rows from a small number of samples with respect to the dimension of the matrix. The method is described in the paper Perrot-Dockès et al. (2019) <arXiv:1806.10093>.

Wraps cytoscape.js as a shiny widget. cytoscape.js <https://js.cytoscape.org/> is a Javascript-based graph theory (network) library for visualization and analysis. This package supports the visualization of networks with custom visual styles and several available layouts. Demo Shiny applications are provided in the package code.

Cleaning and standardizing tabular data package, tailored specifically for curating epidemiological data. It streamlines various data cleaning tasks that are typically expected when working with datasets in epidemiology. It returns the processed data in the same format, and generates a comprehensive report detailing the outcomes of each cleaning task.

Utility functions that allow checking the basic validity of a function argument or any other value, including generating an error and assigning a default in a single line of code. The main purpose of the package is to provide simple and easily readable argument checking to improve code robustness.

Estimation of sparse nonlinear functions in nonparametric regression using component selection and smoothing. Designed for the analysis of high-dimensional data, the models support various data types, including exponential family models and Cox proportional hazards models. The methodology is based on Lin and Zhang (2006) <doi:10.1214/009053606000000722>.

Data are essential in statistical analysis. This data package consists of four datasets for descriptive statistics, two datasets for statistical hypothesis testing, and two datasets for regression analysis. All of the datasets are based on Rattanalertnusorn, A. (2024) <https://www.researchgate.net/publication/371944275_porkaermxarlaeakarprayuktchingan_R_and_its_applications>.

Supports the process of applying a cut to Standard Data Tabulation Model (SDTM), as part of the analysis of specific points in time of the data, normally as part of investigation into clinical trials. The functions support different approaches of cutting to the different domains of SDTM normally observed.

Inspect survival data, plot Kaplan-Meier curves, assess the proportional hazards assumption, fit parametric survival models, predict and plot survival and hazards, and export the outputs to Excel'. A simple interface for fitting survival models using flexsurv::flexsurvreg(), flexsurv::flexsurvspline(), flexsurvcure::flexsurvcure(), and survival::survreg().

This package provides a native R implementation of grammatical evolution (GE). GE facilitates the discovery of programs that can achieve a desired goal. This is done by performing an evolutionary optimisation over a population of R expressions generated via a user-defined context-free grammar (CFG) and cost function.

This package provides functions to fit geostatistical data. The data can be continuous, binary or count data and the models implemented are flexible. Conjugate priors are assumed on some parameters while inference on the other parameters can be done through a full Bayesian analysis of by empirical Bayes methods.

This package provides tools for simulating from spatial modeling of individual level of infectious disease transmission when co-variates measured with error, and carrying out infectious disease data analyses with the same models. The epidemic models considered are distance-based model within Susceptible-Infectious-Removed (SIR) compartmental frameworks.

Easily implement the checking of WHOIS information for a particular domain. IP2WHOIS supports the query for 1113 Top-level Domains(TLDs) and 634 Country Code Top-level Domains(ccTLDs). To get started with a free API key, you may sign up at here <https://www.ip2whois.com/register>.

This package implements inequality constrained inference. This includes parameter estimation in normal (linear) models under linear equality and inequality constraints, as well as normal likelihood ratio tests involving inequality-constrained hypotheses. For inequality-constrained linear models, averaging over R-squared for different orderings of regressors is also included.

Download Internet Protocol (IP) address location and more from the ip-api application programming interface (API) <https://ip-api.com/>. The package makes it easy to get the latitude, longitude, country, region, and organisation associated to the provided IP address. The information is conveniently returned in a rectangular format.

This package implements likelihood-based estimation and diagnostics for multi-type recurrent event data with dynamic risk that depends on prior events and accommodates terminating events. Methods are described in Ghosh, Chan, Younes and Davis (2023) "A Dynamic Risk Model for Multitype Recurrent Events" <doi:10.1093/aje/kwac213>.

Makes Mapbox GL JS <https://docs.mapbox.com/mapbox-gl-js/api/>, an open source JavaScript library that uses WebGL to render interactive maps, available within R via the htmlwidgets package. Visualizations can be used from the R console, in R Markdown documents and in Shiny apps.

Meta-CART integrates classification and regression trees (CART) into meta-analysis. Meta-CART is a flexible approach to identify interaction effects between moderators in meta-analysis. The method is described in Dusseldorp et al. (2014) <doi:10.1037/hea0000018> and Li et al. (2017) <doi:10.1111/bmsp.12088>.

Some functions for performing non-negative matrix factorization, non-negative CANDECOMP/PARAFAC (CP) decomposition, non-negative Tucker decomposition, and generating toy model data. See Andrzej Cichock et al (2009) and the reference section of GitHub README.md <https://github.com/rikenbit/nnTensor>, for details of the methods.

This package provides a shiny application for visualizing high-dimensional data using non-linear dimensionality reduction (NLDR) techniques such as t-SNE and UMAP. It provides an interactive platform to explore high-dimensional datasets, diagnose the quality of the embeddings using the quollr package, and compare different NLDR methods.

It creates a lattice plot to visualize panel or longitudinal data. The observed values are plotted as dots and the fitted values as lines, both against time. The plot is customizable and easy to edit, even if you do not know how to construct a lattice plot from scratch.

An implementation of sparse Gaussian Markov random field mixtures presented by Ide et al. (2016) <doi:10.1109/ICDM.2016.0119>. It provides a novel anomaly detection method for multivariate noisy sensor data. It can automatically handle multiple operational modes. And it can also compute variable-wise anomaly scores.

This package provides a generic framework for working with YAML (YAML Ain't Markup Language) configuration files. Uses ajv (Another JSON Schema Validator) via V8 to validate configurations against JSON Schema definitions. Configuration objects inherit from S7 classes and base lists, supporting downstream extension through custom classes and methods.

This package provides functions for the retrieval, manipulation, and visualization of geospatial data, with an aim towards producing 3D landscape visualizations in the Unity 3D rendering engine. Functions are also provided for retrieving elevation data and base map tiles from the USGS National Map <https://apps.nationalmap.gov/services/>.