This package provides Partial least squares Regression for (weighted) beta regression models (Bertrand 2013, <https://ojs-test.apps.ocp.math.cnrs.fr/index.php/J-SFdS/article/view/215>) and k-fold cross-validation of such models using various criteria. It allows for missing data in the explanatory variables. Bootstrap confidence intervals constructions are also available.

Generalized Least Squares (GLS) estimation of Seemingly Unrelated Regression (SUR) systems on unbalanced panel in the one/two-way cases also taking into account the possibility of cross equation restrictions. Methodological details can be found in Biørn (2004) <doi:10.1016/j.jeconom.2003.10.023> and Platoni, Sckokai, Moro (2012) <doi:10.1080/07474938.2011.607098>.

This package provides a port of the Scarabee toolkit originally written as a Matlab-based application. scaRabee provides a framework for simulation and optimization of pharmacokinetic-pharmacodynamic models at the individual and population level. It is built on top of the neldermead package, which provides the direct search algorithm proposed by Nelder and Mead for model optimization.

Takes one or more fitted Cox proportional hazards models and writes a shiny application to a directory specified by the user. The shiny application displays predicted survival curves based on user input, and contains none of the original data used to create the Cox model or models. The goal is towards visualization and presentation of predicted survival curves.

Uses parametric and nonparametric methods to quantify the proportion of the estimated selection bias (SB) explained by each observed confounder when estimating propensity score weighted treatment effects. Parast, L and Griffin, BA (2020). "Quantifying the Bias due to Observed Individual Confounders in Causal Treatment Effect Estimates". Statistics in Medicine, 39(18): 2447- 2476 <doi: 10.1002/sim.8549>.

Develop spatial interaction models (SIMs). SIMs predict the amount of interaction, for example number of trips per day, between geographic entities representing trip origins and destinations. Contains functions for creating origin-destination datasets from geographic input datasets and calculating movement between origin-destination pairs with constrained, production-constrained, and attraction-constrained models (Wilson 1979) <doi:10.1068/a030001>.

This package provides functions for validating the structure and properties of data frames. Answers essential questions about a data set after initial import or modification. What are the unique or missing values? What columns form a primary key? What are the properties of the numeric or categorical columns? What kind of overlap or mapping exists between 2 columns?

Assess Water Quality Trends for Long-Term Monitoring Data in Estuaries using Generalized Additive Models following Wood (2017) <doi:10.1201/9781315370279> and Error Propagation with Mixed-Effects Meta-Analysis following Sera et al. (2019) <doi:10.1002/sim.8362>. Methods are available for model fitting, assessment of fit, annual and seasonal trend tests, and visualization of results.

Has various functions designed to implement the Hermite-Gaussian Radial Velocity (HGRV) estimation approach of Holzer et al. (2020) <arXiv:2005.14083>, which is a particular application of the radial velocity method for detecting exoplanets. The overall approach consists of four sequential steps, each of which has a function in this package: (1) estimate the template spectrum with the function estimate_template(), (2) find absorption features in the estimated template with the function findabsorptionfeatures(), (3) fit Gaussians to the absorption features with the function Gaussfit(), (4) apply the HGRV with simple linear regression by calling the function hgrv(). This package is meant to be open source. But please cite the paper Holzer et al. (2020) <arXiv:2005.14083> when publishing results that use this package.

Automatic coding of open-ended responses to the Cognitive Reflection Test (CRT), a widely used class of tests in cognitive science and psychology that assess the tendency to override an initial intuitive (but incorrect) answer and engage in reflection to reach a correct solution. The package standardizes CRT response coding across datasets in cognitive psychology, decision-making, and related fields. Automated coding reduces manual effort and improves reproducibility by limiting variability from subjective interpretation of open-ended responses. The package supports automatic coding and machine scoring for the original English-language CRT (Frederick, 2005) <doi:10.1257/089533005775196732>, CRT4 and CRT7 (Toplak et al., 2014) <doi:10.1080/13546783.2013.844729>, CRT-long (Primi et al., 2016) <doi:10.1002/bdm.1883>, and CRT-2 (Thomson & Oppenheimer, 2016) <doi:10.1017/s1930297500007622>.

RaySession is a session manager for audio programs such as Ardour, Carla, QTractor, Guitarix, Patroneo, Jack Mixer, etc. The principle is to load together audio programs, then be able to save or close all documents together. Its main purpose is to manage NSM compatible programs, but it also helps for other programs. It offers a patchbay for visualizing and editing connections.

The sparse nature of single cell epigenomics data can be overruled using probabilistic modelling methods such as Latent Dirichlet Allocation (LDA). This package allows the probabilistic modelling of cis-regulatory topics (cisTopics) from single cell epigenomics data, and includes functionalities to identify cell states based on the contribution of cisTopics and explore the nature and regulatory proteins driving them.

This package is a usability wrapper around snow for easier development of parallel R programs. This package offers e.g. extended error checks, and additional functions. All functions work in sequential mode, too, if no cluster is present or wished. The package is also designed as connector to the cluster management tool sfCluster, but can also used without it.

This package provides a toolkit for all URL-handling needs, including encoding and decoding, parsing, parameter extraction and modification. All functions are designed to be both fast and entirely vectorized. It is intended to be useful for people dealing with web-related datasets, such as server-side logs, although may be useful for other situations involving large sets of URLs.

This package provides a differential evolution (DE) stochastic algorithms for global optimization of problems with and without constraints. The aim is to curate a collection of its state-of-the-art variants that

1. do not sacrifice simplicity of design,

2. are essentially tuning-free, and

3. can be efficiently implemented directly in the R language.

Magrittr provides a mechanism for chaining commands with a new forward-pipe operator, %>%. This operator will forward a value, or the result of an expression, into the next function call/expression. There is flexible support for the type of right-hand side expressions. For more information, see package vignette. To quote Rene Magritte, "Ceci n'est pas un pipe."

This package conveniently wraps all functions needed to reproduce the figures in the IHW paper (https://www.nature.com/articles/nmeth.3885) and the data analysis in https://rss.onlinelibrary.wiley.com/doi/10.1111/rssb.12411, cf. the arXiv preprint (http://arxiv.org/abs/1701.05179). Thus it is a companion package to the Bioconductor IHW package.

The package facilitates implementation of workflows requiring miRNA predictions, it allows to integrate ranked miRNA target predictions from multiple sources available online and aggregate them with various methods which improves quality of predictions above any of the single sources. Currently predictions are available for Homo sapiens, Mus musculus and Rattus norvegicus (the last one through homology translation).

mitology allows to study the mitochondrial activity throught high-throughput RNA-seq data. It is based on a collection of genes whose proteins localize in to the mitochondria. From these, mitology provides a reorganization of the pathways related to mitochondria activity from Reactome and Gene Ontology. Further a ready-to-use implementation of MitoCarta3.0 pathways is included.

Support harvesting of diverse bioinformatic ontologies, making particular use of the ontologyIndex package on CRAN. We provide snapshots of key ontologies for terms about cells, cell lines, chemical compounds, and anatomy, to help analyze genome-scale experiments, particularly cell x compound screens. Another purpose is to strengthen development of compelling use cases for richer interfaces to emerging ontologies.

PhIPData defines an S4 class for phage-immunoprecipitation sequencing (PhIP-seq) experiments. Buliding upon the RangedSummarizedExperiment class, PhIPData enables users to coordinate metadata with experimental data in analyses. Additionally, PhIPData provides specialized methods to subset and identify beads-only samples, subset objects using virus aliases, and use existing peptide libraries to populate object parameters.

Automated Characterization of Health Information at Large-Scale Longitudinal Evidence Systems. Creates a descriptive statistics summary for an Observational Medical Outcomes Partnership Common Data Model standardized data source. This package includes functions for executing summary queries on the specified data source and exporting reporting content for use across a variety of Observational Health Data Sciences and Informatics community applications.

Currently, the package provides several functions for plotting and analyzing bibliometric data (JIF, Journal Impact Factor, and paper percentile values), beamplots with citations and percentiles, and three plot functions to visualize the result of a reference publication year spectroscopy (RPYS) analysis performed in the free software CRExplorer (see <http://crexplorer.net>). Further extension to more plot variants is planned.

Computes density function, cumulative distribution function, quantile function and random numbers for a multisection composite distribution specified by the user. Also fits the user specified distribution to a given data set. More details of the package can be found in the following paper submitted to the R journal Wiegand M and Nadarajah S (2017) CompDist: Multisection composite distributions.