This package provides a local haplotyping visualization toolbox to capture major patterns of co-inheritance between clusters of linked variants, whilst connecting findings to phenotypic and demographic traits across individuals. crosshap enables users to explore and understand genomic variation across a trait-associated region. For an example of successful local haplotype analysis, see Marsh et al. (2022) <doi:10.1007/s00122-022-04045-8>.

Visualize the connectedness of factors in two-way tables. Perform two-way filtering to improve the degree of connectedness. See Weeks & Williams (1964) <doi:10.1080/00401706.1964.10490188>.

Design functions for DCMs and other types of choice studies (including MaxDiff and other tradeoffs).

Core visualizations and summaries for the CRAN package database. The package provides comprehensive methods for cleaning up and organizing the information in the CRAN package database, for building package directives networks (depends, imports, suggests, enhances, linking to) and collaboration networks, producing package dependence trees, and for computing useful summaries and producing interactive visualizations from the resulting networks and summaries. The resulting networks can be coerced to igraph <https://CRAN.R-project.org/package=igraph> objects for further analyses and modelling.

This package implements the three-step workflow for robust analysis of change in two repeated measurements of continuous outcomes, described in Ning et al. (in press), "Robust estimation of the effect of an exposure on the change in a continuous outcome", BMC Medical Research Methodology.

The issue of overlapping regions in multidimensional data arises when different classes or clusters share similar feature representations, making it challenging to delineate distinct boundaries between them accurately. This package provides methods for detecting and visualizing these overlapping regions using partitional clustering techniques based on nearest neighbor distances.

Create rich command line applications, with colors, headings, lists, alerts, progress bars, etc. It uses CSS for custom themes. This package is now superseded by the cli package. Please use cli instead in new projects.

In many cases, experiments must be repeated across multiple seasons or locations to ensure applicability of findings. A single experiment conducted in one location and season may yield limited conclusions, as results can vary under different environmental conditions. In agricultural research, treatment à location and treatment à season interactions play a crucial role. Analyzing a series of experiments across diverse conditions allows for more generalized and reliable recommendations. The CANE package facilitates the pooled analysis of experiments conducted over multiple years, seasons, or locations. It is designed to assess treatment interactions with environmental factors (such as location and season) using various experimental designs. The package supports pooled analysis of variance (ANOVA) for the following designs: (1) PooledCRD()': completely randomized design; (2) PooledRBD()': randomized block design; (3) PooledLSD()': Latin square design; (4) PooledSPD()': split plot design; and (5) PooledStPD()': strip plot design. Each function provides the following outputs: (i) Individual ANOVA tables based on independent analysis for each location or year; (ii) Testing of homogeneity of error variances among distinct locations using Bartlettâ s Chi-Square test; (iii) If Bartlettâ s test is significant, Aitkenâ s transformation, defined as the ratio of the response to the square root of the error mean square, is applied to the response variable; otherwise, the data is used as is; (iv) Combined analysis to obtain a pooled ANOVA table; (v) Multiple comparison tests, including Tukey's honestly significant difference (Tukey's HSD) test, Duncanâ s multiple range test (DMRT), and the least significant difference (LSD) test, for treatment comparisons. The statistical theory and steps of analysis of these designs are available in Dean et al. (2017)<doi:10.1007/978-3-319-52250-0> and Ruà z et al. (2024)<doi:10.1007/978-3-031-65575-3>. By broadening the scope of experimental conclusions, CANE enables researchers to derive robust, widely applicable recommendations. This package is particularly valuable in agricultural research, where accounting for treatment à location and treatment à season interactions is essential for ensuring the validity of findings across multiple settings.

Computes the coverage correlation coefficient introduced in <doi:10.48550/arXiv.2508.06402> , a statistical measure that quantifies dependence between two random vectors by computing the union volume of data-centered hypercubes in a uniform space.

This package provides a simple countdown timer for slides and HTML documents written in R Markdown or Quarto'. Integrates fully into Shiny apps. Countdown to something amazing.

This package provides a genome-wide survival framework that integrates sequential conditional independent tuples and saddlepoint approximation method, to provide SNP-level false discovery rate control while improving power, particularly for biobank-scale survival analyses with low event rates. The method is based on model-X knockoffs as described in Barber and Candes (2015) <doi:10.1214/15-AOS1337> and fast survival analysis methods from Bi et al. (2020) <doi:10.1016/j.ajhg.2020.06.003>. A shrinkage algorithmic leveraging accelerates multiple knockoffs generation in large genetic cohorts. This CRAN version uses standard Cox regression for association testing. For enhanced performance on very large datasets, users may optionally install the SPACox package from GitHub which provides saddlepoint approximation methods for survival analysis.

This package provides four variants of three-way correspondence analysis (ca): three-way symmetrical ca, three-way non-symmetrical ca, three-way ordered symmetrical ca and three-way ordered non-symmetrical ca.

Fit continuous-time correlated random walk models with time indexed covariates to animal telemetry data. The model is fit using the Kalman-filter on a state space version of the continuous-time stochastic movement process.

In statistical modeling, multiple models need to be compared based on certain criteria. The method described here uses eight metrics from AllMetrics package. â input_dfâ is the data frame (at least two columns for comparison) containing metrics values in different rows of a column (which denotes a particular modelâ s performance). First five metrics are expected to be minimum and last three metrics are expected to be maximum for a model to be considered good. Firstly, every metric value (among first five) is searched in every columns and minimum values are denoted as â MINâ and other values are denoted as â NAâ . Secondly, every metric (among last three) is searched in every columns and maximum values are denoted as â MAXâ and other values are denoted as â NAâ . â output_dfâ contains the similar number of rows (which is 8) and columns (which is number of models to be compared) as of â input_dfâ . Values in â output_dfâ are corresponding â NAâ , â MINâ or â MAXâ . Finally, the column containing minimum number of â NAâ values is denoted as the best column. â min_NA_colâ gives the name of the best column (model). â min_NA_valuesâ are the corresponding metrics values. âBestColumn_metricsâ is the data frame (dimension: 1*8) containing different metrics of the best column (model). â best_column_resultsâ is the final result (a list) containing all of these output elements. In special case, if two columns having equal NA', it will be checked among these two column which one is having least NA in first five rows and will be inferred as the best. More details about AllMetrics can be found in Garai (2023) <doi:10.13140/RG.2.2.18688.30723>.

Unifying an inconsistently coded categorical variable between two different time points in accordance with a mapping table. The main rule is to replicate the observation if it could be assigned to a few categories. Then using frequencies or statistical methods to approximate the probabilities of being assigned to each of them. This procedure was invented and implemented in the paper by Nasinski, Majchrowska, and Broniatowska (2020) <doi:10.24425/cejeme.2020.134747>.

Estimate bivariate common mean vector under copula models with known correlation. In the current version, available copulas are the Clayton, Gumbel, Frank, Farlie-Gumbel-Morgenstern (FGM), and normal copulas. See Shih et al. (2019) <doi:10.1080/02331888.2019.1581782> and Shih et al. (2021) <under review> for details under the FGM and general copulas, respectively.

The Concordance Test is a non-parametric method for testing whether two o more samples originate from the same distribution. It extends the Kendall Tau correlation coefficient when there are only two groups. For details, see Alcaraz J., Anton-Sanchez L., Monge J.F. (2022) The Concordance Test, an Alternative to Kruskal-Wallis Based on the Kendall-tau Distance: An R Package. The R Journal 14, 26â 53 <doi:10.32614/RJ-2022-039>.

Test for cluster tendency (clusterability) of a data set. The methods implemented - reducing the data set to a single dimension using principal component analysis or computing pairwise distances, and performing a multimodality test like the Dip Test or Silverman's Critical Bandwidth Test - are described in Adolfsson, Ackerman, and Brownstein (2019) <doi:10.1016/j.patcog.2018.10.026>. Such methods can inform whether clustering algorithms are appropriate for a data set.

Chemical analysis of proteins based on their amino acid compositions. Amino acid compositions can be read from FASTA files and used to calculate chemical metrics including carbon oxidation state and stoichiometric hydration state, as described in Dick et al. (2020) <doi:10.5194/bg-17-6145-2020>. Other properties that can be calculated include protein length, grand average of hydropathy (GRAVY), isoelectric point (pI), molecular weight (MW), standard molal volume (V0), and metabolic costs (Akashi and Gojobori, 2002 <doi:10.1073/pnas.062526999>; Wagner, 2005 <doi:10.1093/molbev/msi126>; Zhang et al., 2018 <doi:10.1038/s41467-018-06461-1>). A database of amino acid compositions of human proteins derived from UniProt is provided.

It is assumed that psychological distances between the categories are equal for the measurement instruments consisted of polytomously scored items. According to Muraki, this assumption must be tested. In the examination process of this assumption, the fit indexes are obtained and evaluated. This package provides that this assumption is removed. By with this package, the converted scale values of all items in a measurement instrument can be calculated by estimating a category parameter set for each item. Thus, the calculations can be made without any need to usage of the common category parameter set. Through this package, the psychological distances of the items are scaled. The scaling of a category parameter set for each item cause differentiation of score of the categories will be got from items. Also, the total measurement instrument score of an individual can be calculated according to the scaling of item score categories by with this package.This package provides that the place of individuals related to the structure to be measured with a measurement instrument consisted of polytomously scored items can be reveal more accurately. In this way, it is thought that the results obtained about individuals can be made more sensitive, and the differences between individuals can be revealed more accurately. On the other hand, it can be argued that more accurate evidences can be obtained regarding the psychometric properties of the measurement instruments.

This package contains the prepared data that is needed for the shiny application examples in the canvasXpress package. This package also includes datasets used for automated testthat tests. Scotto L, Narayan G, Nandula SV, Arias-Pulido H et al. (2008) <doi:10.1002/gcc.20577>. Davis S, Meltzer PS (2007) <doi:10.1093/bioinformatics/btm254>.

The Clinical Trials Network (CTN) of the U.S. National Institute of Drug Abuse sponsored the CTN-0094 research team to harmonize data sets from three nationally-representative clinical trials for opioid use disorder (OUD). The CTN-0094 team herein provides a coded collection of trial outcomes and endpoints used in various OUD clinical trials over the past 50 years. These coded outcome functions are used to contrast and cluster different clinical outcome functions based on daily or weekly patient urine screenings. Note that we abbreviate urine drug screen as "UDS" and urine opioid screen as "UOS". For the example data sets (based on clinical trials data harmonized by the CTN-0094 research team), UDS and UOS are largely interchangeable.

This package provides a cascade select widget for usage in Shiny applications. This is useful for selection of hierarchical choices (e.g. continent, country, city). It is taken from the JavaScript library PrimeReact'.

This package provides a specialized tool is designed for assessing contextual bandit algorithms, particularly those aimed at handling overdispersed and zero-inflated count data. It offers a simulated testing environment that includes various models like Poisson, Overdispersed Poisson, Zero-inflated Poisson, and Zero-inflated Overdispersed Poisson. The package is capable of executing five specific algorithms: Linear Thompson sampling with log transformation on the outcome, Thompson sampling Poisson, Thompson sampling Negative Binomial, Thompson sampling Zero-inflated Poisson, and Thompson sampling Zero-inflated Negative Binomial. Additionally, it can generate regret plots to evaluate the performance of contextual bandit algorithms. This package is based on the algorithms by Liu et al. (2023) <arXiv:2311.14359>.