This package provides functions to calculate Divisia monetary aggregates index as given in Barnett, W. A. (1980) (<DOI:10.1016/0304-4076(80)90070-6>).

Data Analysis using Bootstrap-Coupled ESTimation. Estimation statistics is a simple framework that avoids the pitfalls of significance testing. It uses familiar statistical concepts: means, mean differences, and error bars. More importantly, it focuses on the effect size of one's experiment/intervention, as opposed to a false dichotomy engendered by P values. An estimation plot has two key features: 1. It presents all datapoints as a swarmplot, which orders each point to display the underlying distribution. 2. It presents the effect size as a bootstrap 95% confidence interval on a separate but aligned axes. Estimation plots are introduced in Ho et al., Nature Methods 2019, 1548-7105. <doi:10.1038/s41592-019-0470-3>. The free-to-view PDF is located at <https://www.nature.com/articles/s41592-019-0470-3.epdf?author_access_token=Euy6APITxsYA3huBKOFBvNRgN0jAjWel9jnR3ZoTv0Pr6zJiJ3AA5aH4989gOJS_dajtNr1Wt17D0fh-t4GFcvqwMYN03qb8C33na_UrCUcGrt-Z0J9aPL6TPSbOxIC-pbHWKUDo2XsUOr3hQmlRew%3D%3D>.

Supports the process of applying a cut to Standard Data Tabulation Model (SDTM), as part of the analysis of specific points in time of the data, normally as part of investigation into clinical trials. The functions support different approaches of cutting to the different domains of SDTM normally observed.

Simultaneously detect the number and locations of change points in piecewise linear models under stationary Gaussian noise allowing autocorrelated random noise. The core idea is to transform the problem of detecting change points into the detection of local extrema (local maxima and local minima)through kernel smoothing and differentiation of the data sequence, see Cheng et al. (2020) <doi:10.1214/20-EJS1751>. A low-computational and fast algorithm call dSTEM is introduced to detect change points based on the STEM algorithm in D. Cheng and A. Schwartzman (2017) <doi:10.1214/16-AOS1458>.

Fit logistic functions to observed dose-response continuous data and evaluate goodness-of-fit measures. See Malyutina A., Tang J., and Pessia A. (2023) <doi:10.18637/jss.v106.i04>.

For checking the dataset from EDC(Electronic Data Capture) in clinical trials. dmtools reshape your dataset in a tidy view and check events. You can reshape the dataset and choose your target to check, for example, the laboratory reference range.

This package provides a full definition for Weibull tails and Full-Tails Gamma and tools for fitting these distributions to empirical tails. This package build upon the paper by del Castillo, Joan & Daoudi, Jalila & Serra, Isabel. (2012) <doi:10.1017/asb.2017.9>.

Data science methods used in wind energy applications. Current functionalities include creating a multi-dimensional power curve model, performing power curve function comparison, covariate matching, and energy decomposition. Relevant works for the developed functions are: funGP() - Prakash et al. (2022) <doi:10.1080/00401706.2021.1905073>, AMK() - Lee et al. (2015) <doi:10.1080/01621459.2014.977385>, tempGP() - Prakash et al. (2022) <doi:10.1080/00401706.2022.2069158>, ComparePCurve() - Ding et al. (2021) <doi:10.1016/j.renene.2021.02.136>, deltaEnergy() - Latiffianti et al. (2022) <doi:10.1002/we.2722>, syncSize() - Latiffianti et al. (2022) <doi:10.1002/we.2722>, imptPower() - Latiffianti et al. (2022) <doi:10.1002/we.2722>, All other functions - Ding (2019, ISBN:9780429956508).

Fits dose-response models utilizing a Bayesian model averaging approach as outlined in Gould (2019) <doi:10.1002/bimj.201700211> for both continuous and binary responses. Longitudinal dose-response modeling is also supported in a Bayesian model averaging framework as outlined in Payne, Ray, and Thomann (2024) <doi:10.1080/10543406.2023.2292214>. Functions for plotting and calculating various posterior quantities (e.g. posterior mean, quantiles, probability of minimum efficacious dose, etc.) are also implemented. Copyright Eli Lilly and Company (2019).

An interface to explore, analyze, and visualize droplet digital PCR (ddPCR) data in R. This is the first non-proprietary software for analyzing two-channel ddPCR data. An interactive tool was also created and is available online to facilitate this analysis for anyone who is not comfortable with using R.

Leverages dplyr to process the calculations of a plot inside a database. This package provides helper functions that abstract the work at three levels: outputs a ggplot', outputs the calculations, outputs the formula needed to calculate bins.

Inference functionalities for distributed-lag linear structural equation models (DLSEMs). DLSEMs are Markovian structural causal models where each factor of the joint probability distribution is a distributed-lag linear regression with constrained lag shapes (Magrini, 2018 <doi:10.2478/bile-2018-0012>; Magrini et al., 2019 <doi:10.1007/s11135-019-00855-z>). DLSEMs account for temporal delays in the dependence relationships among the variables through a single parameter per covariate, thus allowing to perform dynamic causal inference in a feasible fashion. Endpoint-constrained quadratic, quadratic decreasing, linearly decreasing and gamma lag shapes are available.

An anonymization algorithm to resist neighbor label attack in a dynamic network.

This package provides a different way for calculating pdf/pmf, cdf, quantile and random data such that the user is able to consider the name of related distribution as an argument and so easily can changed by a changing argument by user. It must be mentioned that the core and computation base of package DISTRIB is package stats'. Although similar functions are introduced previously in package stats', but the package DISTRIB has some special applications in some special computational programs.

This package provides a framework for the replicable removal of personally identifiable data (PID) in data sets. The package implements a suite of methods to suit different data types based on the suggestions of Garfinkel (2015) <doi:10.6028/NIST.IR.8053> and the ICO "Guidelines on Anonymization" (2012) <https://ico.org.uk/media/1061/anonymisation-code.pdf>.

Builds interactive d3.js hierarchical visualisation easily. D3partitionR makes it easy to build and customize sunburst, circle treemap, treemap, partition chart, ...

Could be used to obtain spatial depths, spatial ranks and outliers of multivariate random variables. Could also be used to visualize DD-plots (a multivariate generalization of QQ-plots).

Prepare the results of a DCE to be analysed through choice models.'DCEmgmt reshapes DCE data from wide to long format considering the special characteristics of a DCE. DCEmgmt includes the function DCEestm which estimates choice models once the database has been reshaped with DCEmgmt'.

Implementation of Das Gupta's standardisation and decomposition of population rates, as set out "Standardization and decomposition of rates: A userâ s manual", Das Gupta (1993) <https://www2.census.gov/library/publications/1993/demographics/p23-186.pdf>. The goal of these methods is to calculate adjusted rates based on compositional factors and quantify the contribution of each factor to the difference in crude rates between populations. The package offers functionality to handle various scenarios for any number of factors and populations, where said factors can be comprised of vectors across sub-populations (including cross-classified population breakdowns), and with the option to specify user-defined rate functions.

Compressed spatial vector data originally from <https://dawadocs.dataforsyningen.dk/> saved as Simple Features, SF, objects with data on population, age and gender from Statistics Denmark <https://www.dst.dk/da/>.

While it has been well established that drugs affect and help patients differently, personalized drug response predictions remain challenging. Solutions based on single omics measurements have been proposed, and networks provide means to incorporate molecular interactions into reasoning. However, how to integrate the wealth of information contained in multiple omics layers still poses a complex problem. We present a novel network analysis pipeline, DrDimont, Drug response prediction from Differential analysis of multi-omics networks. It allows for comparative conclusions between two conditions and translates them into differential drug response predictions. DrDimont focuses on molecular interactions. It establishes condition-specific networks from correlation within an omics layer that are then reduced and combined into heterogeneous, multi-omics molecular networks. A novel semi-local, path-based integration step ensures integrative conclusions. Differential predictions are derived from comparing the condition-specific integrated networks. DrDimont's predictions are explainable, i.e., molecular differences that are the source of high differential drug scores can be retrieved. Our proposed pipeline leverages multi-omics data for differential predictions, e.g. on drug response, and includes prior information on interactions. The case study presented in the vignette uses data published by Krug (2020) <doi:10.1016/j.cell.2020.10.036>. The package license applies only to the software and explicitly not to the included data.

Plots dependency logos from a set of aligned input sequences.

Summarise patient-level drug utilisation cohorts using data mapped to the Observational Medical Outcomes Partnership (OMOP) common data model. New users and prevalent users cohorts can be generated and their characteristics, indication and drug use summarised.

Discrete factor analysis for dependent Poisson and negative binomial models with truncation, zero inflation, and zero inflated truncation.