Improves the predictive performance of ridge and lasso regression exploiting one or more sources of prior information on the importance and direction of effects (Rauschenberger and others 2023, <doi:10.1093/bioinformatics/btad680>). For running the vignette (optional), install fwelnet from GitHub <https://github.com/kjytay/fwelnet>.

Multiple ways to bin numeric columns with a tidy output. Wraps a variety of existing binning methods into one function, and includes a new method for binning by equal value, which is useful for sales data. Provides a function to automatically summarize the properties of the binned columns.

This package provides a set of tools to create a UK Biobank <http://www.ukbiobank.ac.uk/> dataset from a UKB fileset (.tab, .r, .html), visualize primary demographic data for a sample subset, query ICD diagnoses, retrieve genetic metadata, read and write standard file formats for genetic analyses.

This package performs clustering of quantitative variables, assuming that clusters lie in low-dimensional subspaces. Segmentation of variables, number of clusters and their dimensions are selected based on BIC. Candidate models are identified based on many runs of K-means algorithm with different random initializations of cluster centers.

Allow R users to interact with the Canvas Learning Management System (LMS) API (see <https://canvas.instructure.com/doc/api/all_resources.html> for details). It provides a set of functions to access and manipulate course data, assignments, grades, users, and other resources available through the Canvas API.

Data driven strategy to find hidden groups of patients with complex diseases using clinical data. ClustAll facilitates the unsupervised identification of multiple robust stratifications. ClustAll, is able to overcome the most common limitations found when dealing with clinical data (missing values, correlated data, mixed data types).

HMP2Data is a Bioconductor package of the Human Microbiome Project 2 (HMP2) 16S rRNA sequencing data. Processed data is provided as phyloseq, SummarizedExperiment, and MultiAssayExperiment class objects. Individual matrices and data.frames used for building these S4 class objects are also provided in the package.

svaRetro contains functions for detecting retrotransposed transcripts (RTs) from structural variant calls. It takes structural variant calls in GRanges of breakend notation and identifies RTs by exon-exon junctions and insertion sites. The candidate RTs are reported by events and annotated with information of the inserted transcripts.

`tomoseqr` is an R package for analyzing Tomo-seq data. Tomo-seq is a genome-wide RNA tomography method that combines combining high-throughput RNA sequencing with cryosectioning for spatially resolved transcriptomics. `tomoseqr` reconstructs 3D expression patterns from tomo-seq data and visualizes the reconstructed 3D expression patterns.

MaAsLin2 is comprehensive R package for efficiently determining multivariable association between clinical metadata and microbial meta'omic features. This package relies on general linear models to accommodate most modern epidemiological study designs, including cross-sectional and longitudinal, and offers a variety of data exploration, normalization, and transformation methods.

This package can be used to normalize cytometry samples when a control sample is taken along in each of the batches. This is done by first identifying multiple clusters/cell types, learning the batch effects from the control samples and applying quantile normalization on all markers of interest.

This package provides functions for interacting directly with the ALTADATA API. With this R package, developers can build applications around the ALTADATA API without having to deal with accessing and managing requests and responses. ALTADATA is a curated data marketplace for more information go to <https://www.altadata.io>.

Fit Generalized Additive Models (GAM) using mgcv with parsnip'/'tidymodels via additive <doi:10.5281/zenodo.4784245>. tidymodels is a collection of packages for machine learning; see Kuhn and Wickham (2020) <https://www.tidymodels.org>). The technical details of mgcv are described in Wood (2017) <doi:10.1201/9781315370279>.

Computation of large covariance matrices having a block structure up to a permutation of their columns and rows from a small number of samples with respect to the dimension of the matrix. The method is described in the paper Perrot-Dockès et al. (2019) <arXiv:1806.10093>.

Wraps cytoscape.js as a shiny widget. cytoscape.js <https://js.cytoscape.org/> is a Javascript-based graph theory (network) library for visualization and analysis. This package supports the visualization of networks with custom visual styles and several available layouts. Demo Shiny applications are provided in the package code.

Cleaning and standardizing tabular data package, tailored specifically for curating epidemiological data. It streamlines various data cleaning tasks that are typically expected when working with datasets in epidemiology. It returns the processed data in the same format, and generates a comprehensive report detailing the outcomes of each cleaning task.

Estimation of sparse nonlinear functions in nonparametric regression using component selection and smoothing. Designed for the analysis of high-dimensional data, the models support various data types, including exponential family models and Cox proportional hazards models. The methodology is based on Lin and Zhang (2006) <doi:10.1214/009053606000000722>.

Utility functions that allow checking the basic validity of a function argument or any other value, including generating an error and assigning a default in a single line of code. The main purpose of the package is to provide simple and easily readable argument checking to improve code robustness.

Data are essential in statistical analysis. This data package consists of four datasets for descriptive statistics, two datasets for statistical hypothesis testing, and two datasets for regression analysis. All of the datasets are based on Rattanalertnusorn, A. (2024) <https://www.researchgate.net/publication/371944275_porkaermxarlaeakarprayuktchingan_R_and_its_applications>.

Supports the process of applying a cut to Standard Data Tabulation Model (SDTM), as part of the analysis of specific points in time of the data, normally as part of investigation into clinical trials. The functions support different approaches of cutting to the different domains of SDTM normally observed.

For estimation of a variable of interest using Kalman filter by incorporating results from previous assessments, i.e. through development weighted estimates where weights are assigned inversely proportional to the variance of existing and new estimates. For reference see Ehlers et al. (2017) <doi:10.20944/preprints201710.0098.v1>.

Inspect survival data, plot Kaplan-Meier curves, assess the proportional hazards assumption, fit parametric survival models, predict and plot survival and hazards, and export the outputs to Excel. A simple interface for fitting survival models using flexsurv::flexsurvreg()', flexsurv::flexsurvspline()', flexsurvcure::flexsurvcure()', and survival::survreg()'.

This package provides a native R implementation of grammatical evolution (GE). GE facilitates the discovery of programs that can achieve a desired goal. This is done by performing an evolutionary optimisation over a population of R expressions generated via a user-defined context-free grammar (CFG) and cost function.

This package provides tools for simulating from spatial modeling of individual level of infectious disease transmission when co-variates measured with error, and carrying out infectious disease data analyses with the same models. The epidemic models considered are distance-based model within Susceptible-Infectious-Removed (SIR) compartmental frameworks.