Proposed by Harrell, the C index or concordance C, is considered an overall measure of discrimination in survival analysis between a survival outcome that is possibly right censored and a predictive-score variable, which can represent a measured biomarker or a composite-score output from an algorithm that combines multiple biomarkers. This package aims to statistically compare two C indices with right-censored survival outcome, which commonly arise from a paired design and thus resulting two correlated C indices.

This package provides a wrapper for the Clockify API <https://docs.clockify.me/>, making it possible to query, insert and update time keeping data.

This package provides a method for pattern discovery in weighted graphs as outlined in Thistlethwaite et al. (2021) <doi:10.1371/journal.pcbi.1008550>. Two use cases are achieved: 1) Given a weighted graph and a subset of its nodes, do the nodes show significant connectedness? 2) Given a weighted graph and two subsets of its nodes, are the subsets close neighbors or distant?

An interactive document on the topic of classification tree analysis using rmarkdown and shiny packages. Runtime examples are provided in the package function as well as at <https://kartikeyab.shinyapps.io/CTShiny/>.

Utility functions to facilitate the import, the reporting and analysis of clinical data. Example datasets in SDTM and ADaM format, containing a subset of patients/domains from the CDISC Pilot 01 study are also available as R datasets to demonstrate the package functionalities.

Calculates confidence intervals after variable selection using repeated data splits. The package offers methods to address the challenges of post-selection inference, ensuring more accurate confidence intervals in models involving variable selection. The two main functions are lmps', which records the different models selected across multiple data splits as well as the corresponding coefficient estimates, and cips', which takes the lmps object as input to select variables and perform inferences using two types of voting.

This package provides the ability to create interaction maps, discover CNV map domains (edges), gene annotate interactions, and create interactive visualizations of these CNV interaction maps.

Connect to the California Irrigation Management Information System (CIMIS) Web API. See the CIMIS main page <https://cimis.water.ca.gov> and web API documentation <https://et.water.ca.gov> for more information.

Implementation of the d/p/q/r family of functions for a continuous analog to the standard discrete beta-binomial with continuous size parameter and continuous support with x in [0, size + 1].

With the development of new cross-cultural methods this package is intended to combine multiple functions automating and simplifying functions providing a unified analysis approach for commonly employed methods.

This package provides an implementation of â Curricular Analyticsâ , a framework for analyzing and quantifying the complexity of academic curricula. Curricula are modelled as directed acyclic graphs and analytics are provided based on path lengths and edge density. This work directly comes from Heileman et al. (2018) <doi:10.48550/arXiv.1811.09676>.

After using this, a publication-ready correlation table with p-values indicated will be created. The input can be a full data frame; any string and Boolean terms will be dropped as part of functionality. Correlations and p-values are calculated using the Hmisc framework. Output of the correlation_matrix() function is a table of strings; this gets saved out to a .csv2 with the save_correlation_matrix() function for easy insertion into a paper. For more details about the process, consult <https://paulvanderlaken.com/2020/07/28/publication-ready-correlation-matrix-significance-r/>.

Client for CKAN API (<https://ckan.org/>). Includes interface to CKAN APIs for search, list, show for packages, organizations, and resources. In addition, provides an interface to the datastore API.

Evaluates the stability and significance of clusters on igraph graphs. Supports weighted and unweighted graphs. Implements the cluster evaluation methods defined by Arratia A, Renedo M (2021) <doi:10.7717/peerj-cs.600>. Also includes an implementation of the Reduced Mutual Information introduced by Newman et al. (2020) <doi:10.1103/PhysRevE.101.042304>.

Evaluation of default probability of sovereign and corporate entities based on structural or intensity based models and calibration on market Credit Default Swap quotes. References: Damiano Brigo, Massimo Morini, Andrea Pallavicini (2013) <doi:10.1002/9781118818589>. Print ISBN: 9780470748466, Online ISBN: 9781118818589. © 2013 John Wiley & Sons Ltd.

Cluster analysis is performed using pairwise distance information and a random partition distribution. The method is implemented for two random partition distributions. It draws samples and then obtains and plots clustering estimates. An implementation of a selection algorithm is provided for the mass parameter of the partition distribution. Since pairwise distances are the principal input to this procedure, it is most comparable to the hierarchical and k-medoids clustering methods. The method is Dahl, Andros, Carter (2022+) <doi:10.1002/sam.11602>.

Chemical analysis of proteins based on their amino acid compositions. Amino acid compositions can be read from FASTA files and used to calculate chemical metrics including carbon oxidation state and stoichiometric hydration state, as described in Dick et al. (2020) <doi:10.5194/bg-17-6145-2020>. Other properties that can be calculated include protein length, grand average of hydropathy (GRAVY), isoelectric point (pI), molecular weight (MW), standard molal volume (V0), and metabolic costs (Akashi and Gojobori, 2002 <doi:10.1073/pnas.062526999>; Wagner, 2005 <doi:10.1093/molbev/msi126>; Zhang et al., 2018 <doi:10.1038/s41467-018-06461-1>). A database of amino acid compositions of human proteins derived from UniProt is provided.

Inference with control function methods for nonlinear outcome models when the model is known ('Guo and Small (2016) <arXiv:1602.01051>) and when unknown but semiparametric ('Li and Guo (2021) <arXiv:2010.09922>).

In searching for research articles, we often want to obtain lists of references from across studies, and also obtain lists of articles that cite a particular study. In systematic reviews, this supplementary search technique is known as citation chasing': forward citation chasing looks for all records citing one or more articles of known relevance; backward citation chasing looks for all records referenced in one or more articles. Traditionally, this process would be done manually, and the resulting records would need to be checked one-by-one against included studies in a review to identify potentially relevant records that should be included in a review. This package contains functions to automate this process by making use of the Lens.org API. An input article list can be used to return a list of all referenced records, and/or all citing records in the Lens.org database (consisting of PubMed, PubMed Central, CrossRef, Microsoft Academic Graph and CORE; <https://www.lens.org>).

These functions implement collocation-inference for continuous-time and discrete-time stochastic processes. They provide model-based smoothing, gradient-matching, generalized profiling and forwards prediction error methods.

This package provides a framework is provided to develop R packages using Rust <https://www.rust-lang.org/> with minimal overhead, and more wrappers are easily added. Help is provided to use Cargo <https://doc.rust-lang.org/cargo/> in a manner consistent with CRAN policies. Rust code can also be embedded directly in an R script. The package is not official, affiliated with, nor endorsed by the Rust project.

An exact and a variational inference for coupled Hidden Markov Models applied to the joint detection of copy number variations.

This package provides tools for the analysis, visualization, and manipulation of dynamical, social (Saqr et al. (2024) <doi:10.1007/978-3-031-54464-4_10>) and complex networks (Saqr et al. (2025) <doi:10.1145/3706468.3706513>). The package supports multiple network formats and offers flexible tools for heterogeneous, multi-layer, and hierarchical network analysis with simple syntax and extensive toolset.

This package provides a set of tools for evaluating clustering robustness using proportion of ambiguously clustered pairs (Senbabaoglu et al. (2014) <doi:10.1038/srep06207>), as well as similarity across methods and method stability using element-centric clustering comparison (Gates et al. (2019) <doi:10.1038/s41598-019-44892-y>). Additionally, this package enables stability-based parameter assessment for graph-based clustering pipelines typical in single-cell data analysis.