Browser cookies are name-value pairs that are saved in a user's browser by a website. Cookies allow websites to persist information about the user and their use of the website. Here we provide tools for working with cookies in shiny apps, in part by wrapping the js-cookie JavaScript library <https://github.com/js-cookie/js-cookie>.

Reconstruct networks from multi-omics data sets with the collaborative graphical lasso (coglasso) algorithm described in Albanese, A., Kohlen, W., and Behrouzi, P. (2024) <doi:10.48550/arXiv.2403.18602>. Use the main wrapper function `bs()` to build and select a multi-omics network.

Computes the maximum likelihood estimator, the smoothed maximum likelihood estimator and pointwise bootstrap confidence intervals for the distribution function under current status data. Groeneboom and Hendrickx (2017) <doi:10.1214/17-EJS1345>.

Calculations of "EP15-A3 document. A manual for user verification of precision and estimation of bias" CLSI (2014, ISBN:1-56238-966-1).

Fast and memory-efficient (or cheap') tools to facilitate efficient programming, saving time and memory. It aims to provide cheaper alternatives to common base R functions, as well as some additional functions.

Modeling periodic mortality (or other time-to event) processes from right-censored data. Given observations of a process with a known period (e.g. 365 days, 24 hours), functions determine the number, intensity, timing, and duration of peaks of periods of elevated hazard within a period. The underlying model is a mixed wrapped Cauchy function fitted using maximum likelihoods (details in Gurarie et al. (2020) <doi:10.1111/2041-210X.13305>). The development of these tools was motivated by the strongly seasonal mortality patterns observed in many wild animal populations. Thus, the respective periods of higher mortality can be identified as "mortality seasons".

Utilities that support the usage of pyDarwin (<https://certara.github.io/pyDarwin/>) for ease of setup and execution of a machine learning based pharmacometric model search with Certara's Non-Linear Mixed Effects (NLME) modeling engine.

This package implements the three-step workflow for robust analysis of change in two repeated measurements of continuous outcomes, described in Ning et al. (in press), "Robust estimation of the effect of an exposure on the change in a continuous outcome", BMC Medical Research Methodology.

This package implements Cramer-von Mises Statistics for testing fit to (1) fully specified discrete distributions as described in Choulakian, Lockhart and Stephens (1994) <doi:10.2307/3315828> (2) discrete distributions with unknown parameters that must be estimated from the sample data, see Spinelli & Stephens (1997) <doi:10.2307/3315735> and Lockhart, Spinelli and Stephens (2007) <doi:10.1002/cjs.5550350111> (3) grouped continuous distributions with Unknown Parameters, see Spinelli (2001) <doi:10.2307/3316040>. Maximum likelihood estimation (MLE) is used to estimate the parameters. The package computes the Cramer-von Mises Statistics, Anderson-Darling Statistics and the Watson-Stephens Statistics and their p-values.

Integrated, convenient, and uniform access to Canadian Census data and geography retrieved using the CensusMapper API. This package produces analysis-ready tidy data frames and spatial data in multiple formats, as well as convenience functions for working with Census variables, variable hierarchies, and region selection. API keys are freely available with free registration at <https://censusmapper.ca/api>. Census data and boundary geometries are reproduced and distributed on an "as is" basis with the permission of Statistics Canada (Statistics Canada 1996; 2001; 2006; 2011; 2016; 2021).

Manipulate and analyze 3-D structural geometry of Protein Data Bank (PDB) files.

Enables creation of visualizations using the CanvasXpress framework in R. CanvasXpress is a standalone JavaScript library for reproducible research with complete tracking of data and end-user modifications stored in a single PNG image that can be played back. See <https://www.canvasxpress.org> for more information.

Provide a series of functions to conduct a meta analysis of factor analysis based on co-occurrence matrices. The tool can be used to solve the factor structure (i.e. inner structure of a construct, or scale) debate in several disciplines, such as psychology, psychiatry, management, education so on. References: Shafer (2005) <doi:10.1037/1040-3590.17.3.324>; Shafer (2006) <doi:10.1002/jclp.20213>; Loeber and Schmaling (1985) <doi:10.1007/BF00910652>.

Generate a candidate code list for the Observational Medical Outcomes Partnership (OMOP) common data model based on string matching. For a given search strategy, a candidate code list will be returned.

This package provides functions for hit gene identification and quantification of sgRNA (single-guided RNA) abundances for CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) pooled screen data analysis. Details are in Jeong et al. (2019) <doi:10.1101/gr.245571.118> and Baggerly et al. (2003) <doi:10.1093/bioinformatics/btg173>.

This package provides functions to perform comparative causal mediation analysis to compare the mediation effects of different treatments via a common mediator. Results contain the estimates and confidence intervals for the two comparative causal mediation analysis estimands, as well as the ATE and ACME for each treatment. Functions provided in the package will automatically assess the comparative causal mediation analysis scope conditions (i.e. for each comparative causal mediation estimand, a numerator and denominator that are both estimated with the desired statistical significance and of the same sign). Results will be returned for each comparative causal mediation estimand only if scope conditions are met for it. See details in Bansak(2020)<doi:10.1017/pan.2019.31>.

Contrast analysis for factorial designs provides an alternative to the traditional ANOVA approach, offering the distinct advantage of testing targeted hypotheses. The foundation of this package is primarily rooted in the works of Rosenthal, Rosnow, and Rubin (2000, ISBN: 978-0521659802) as well as Sedlmeier and Renkewitz (2018, ISBN: 978-3868943214).

Infrastructure for task views to CRAN-style repositories: Querying task views and installing the associated packages (client-side tools), generating HTML pages and storing task view information in the repository (server-side tools).

In computer experiments space-filling designs are having great impact. Most popularly used space-filling designs are Uniform designs (UDs), Latin hypercube designs (LHDs) etc. For further references one can see Mckay (1979) <DOI:10.1080/00401706.1979.10489755> and Fang (1980) <https://cir.nii.ac.jp/crid/1570291225616774784>. In this package, we have provided algorithms for generate efficient LHDs and UDs. Here, generated LHDs are efficient as they possess lower value of Maxpro measure, Phi_p value and Maximum Absolute Correlation (MAC) value based on the weightage given to each criterion. On the other hand, the produced UDs are having good space-filling property as they always attain the lower bound of Discrete Discrepancy measure. Further, some useful functions added in this package for adding more value to this package.

Google's Compact Language Detector 3 is a neural network model for language identification and the successor of cld2 (available from CRAN). The algorithm is still experimental and takes a novel approach to language detection with different properties and outcomes. It can be useful to combine this with the Bayesian classifier results from cld2'. See <https://github.com/google/cld3#readme> for more information.

Allows clinicians to predict survival probabilities over the next two years for cystic fibrosis patients, based on the clinical prediction models published in Stanojevic et al. (2019) <doi:10.1183/13993003.00224-2019>.

Integrates two numerical omics data sets from the same samples using partial correlations. The output can be represented as a network, bipartite graph or a hypergraph structure. The method used in the package refers to Klaus et al (2021) <doi:10.1016/j.molmet.2021.101295>.

Support for import from and export to the CSVY file format. CSVY is a file format that combines the simplicity of CSV (comma-separated values) with the metadata of other plain text and binary formats (JSON, XML, Stata, etc.) by placing a YAML header on top of a regular CSV.

This package provides tools to interface with Cytobank's API via R, organized by endpoints that represent various areas of Cytobank functionality. Learn more about Cytobank at <https://www.beckman.com/flow-cytometry/software>.