This package provides a consistent interface for connecting R to various data sources including file systems and databases. Designed for clinical research, connector streamlines access to ADAM', SDTM for example. It helps to deal with multiple data formats through a standardized API and centralized configuration.

This package performs Bayesian non-parametric calibration of multiple related radiocarbon determinations, and summarises the calendar age information to plot their joint calendar age density (see Heaton (2022) <doi:10.1111/rssc.12599>). Also models the occurrence of radiocarbon samples as a variable-rate (inhomogeneous) Poisson process, plotting the posterior estimate for the occurrence rate of the samples over calendar time, and providing information about potential change points.

Enhances the ini package by adding the ability to interpolate variables. The INI configuration file is read into an R6 ConfigParser object (loosely inspired by Pythons ConfigParser module) and the keys can be read, where %(....)s instances are interpolated by other included options or outside variables.

Given a patient-sharing network, calculate either the classic care density as proposed by Pollack et al. (2013) <doi:10.1007/s11606-012-2104-7> or the fragmented care density as proposed by Engels et al. (2024) <doi:10.1186/s12874-023-02106-0>. By utilizing the igraph and data.table packages, the provided functions scale well for very large graphs.

This package provides functions for hit gene identification and quantification of sgRNA (single-guided RNA) abundances for CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) pooled screen data analysis. Details are in Jeong et al. (2019) <doi:10.1101/gr.245571.118> and Baggerly et al. (2003) <doi:10.1093/bioinformatics/btg173>.

Function using lemmatization to classify educational programs according to the CINE(Classification International Normalized of Education) for Peru.

CGAL is a C++ library that aims to provide easy access to efficient and reliable algorithms in computational geometry. Since its version 4, CGAL can be used as standalone header-only library and is available under a double GPL-3|LGPL license. <https://www.cgal.org/>.

Retorna detalhes de dados de CEPs brasileiros, bairros, logradouros e tal. (Returns info of Brazilian postal codes, city names, addresses and so on.).

Also abbreviates to "CCSeq". Finds clusters of colocalized sequences in .bed annotation files up to a specified cut-off distance. Two sequences are colocalized if they are within the cut-off distance of each other, and clusters are sets of sequences where each sequence is colocalized to at least one other sequence in the cluster. For a set of .bed annotation tables provided in a list along with a cut-off distance, the program will output a file containing the locations of each cluster. Annotated .bed files are from the pwmscan application at <https://ccg.epfl.ch/pwmtools/pwmscan.php>. Personal machines might crash or take excessively long depending on the number of annotated sequences in each file and whether chromsearch() or gensearch() is used.

This package provides functions to construct finite-sample calibrated predictive intervals for Bayesian models, following the approach in Barber et al. (2021) <doi:10.1214/20-AOS1965>. These intervals are calculated efficiently using importance sampling for the leave-one-out residuals. By default, the intervals will also reflect the relative uncertainty in the Bayesian model, using the locally-weighted conformal methods of Lei et al. (2018) <doi:10.1080/01621459.2017.1307116>.

Doubly robust methods for evaluating surrogate markers as outlined in: Agniel D, Hejblum BP, Thiebaut R & Parast L (2022). "Doubly robust evaluation of high-dimensional surrogate markers", Biostatistics <doi:10.1093/biostatistics/kxac020>. You can use these methods to determine how much of the overall treatment effect is explained by a (possibly high-dimensional) set of surrogate markers.

Reduction-based techniques for cost-sensitive multi-class classification, in which each observation has a different cost for classifying it into one class, and the goal is to predict the class with the minimum expected cost for each new observation. Implements Weighted All-Pairs (Beygelzimer, A., Langford, J., & Zadrozny, B., 2008, <doi:10.1007/978-0-387-79361-0_1>), Weighted One-Vs-Rest (Beygelzimer, A., Dani, V., Hayes, T., Langford, J., & Zadrozny, B., 2005, <https://dl.acm.org/citation.cfm?id=1102358>) and Regression One-Vs-Rest. Works with arbitrary classifiers taking observation weights, or with regressors. Also implements cost-proportionate rejection sampling for working with classifiers that don't accept observation weights.

Computes p-values using the largest root test using an approximation to the null distribution by Johnstone (2008) <DOI:10.1214/08-AOS605>.

Solves for the mean parameters, the variance parameter, and their asymptotic variance in a conditional GEE for recurrent event gap times, as described by Clement and Strawderman (2009) in the journal Biostatistics. Makes a parametric assumption for the length of the censored gap time.

Cross-validation methods of regression models that exploit features of various modeling functions to improve speed. Some of the methods implemented in the package are novel, as described in the package vignettes; for general introductions to cross-validation, see, for example, Gareth James, Daniela Witten, Trevor Hastie, and Robert Tibshirani (2021, ISBN 978-1-0716-1417-4, Secs. 5.1, 5.3), "An Introduction to Statistical Learning with Applications in R, Second Edition", and Trevor Hastie, Robert Tibshirani, and Jerome Friedman (2009, ISBN 978-0-387-84857-0, Sec. 7.10), "The Elements of Statistical Learning, Second Edition".

An API wrapper for Cryptowatch to get prices and other information (e.g., volume, trades, order books, bid and ask prices, live quotes, and more) about cryptocurrencies and crypto exchanges. See <https://docs.cryptowat.ch/rest-api> for a detailed documentation.

This package contains Coverage Adjusted Standardized Mutual Information ('CASMI')-based functions. CASMI is a fundamental concept of a series of methods. For more information about CASMI and CASMI'-related methods, please refer to the corresponding publications (e.g., a feature selection method, Shi, J., Zhang, J., & Ge, Y. (2019) <doi:10.3390/e21121179>, and a dataset quality measurement method, Shi, J., Zhang, J., & Ge, Y. (2019) <doi:10.1109/ICHI.2019.8904553>) or contact the package author for the latest updates.

This code provides several different functions for cleaning and analyzing continuous glucose monitor data. Currently it works with Dexcom', iPro 2', Diasend', Libre', or Carelink data. The cleandata() function takes a directory of CGM data files and prepares them for analysis. cgmvariables() iterates through a directory of cleaned CGM data files and produces a single spreadsheet with data for each file in either rows or columns. The column format of this spreadsheet is compatible with REDCap data upload. cgmreport() also iterates through a directory of cleaned data, and produces PDFs of individual and aggregate AGP plots. Please visit <https://github.com/childhealthbiostatscore/R-Packages/> to download the new-user guide.

This package provides a dashboard supports the usage of cromwell'. Cromwell is a scientific workflow engine for command line users. This package utilizes cromwell REST APIs and provides these convenient functions: timing diagrams for running workflows, cromwell engine status, a tabular workflow list. For more information about cromwell', visit <http://cromwell.readthedocs.io>.

The goal of cvsem is to provide functions that allow for comparing Structural Equation Models (SEM) using cross-validation. Users can specify multiple SEMs using lavaan syntax. cvsem computes the Kullback Leibler (KL) Divergence between 1) the model implied covariance matrix estimated from the training data and 2) the sample covariance matrix estimated from the test data described in Cudeck, Robert & Browne (1983) <doi:10.18637/jss.v048.i02>. The KL Divergence is computed for each of the specified SEMs allowing for the models to be compared based on their prediction errors.

This package contains the Correlates of State Policy Project dataset (+ codebook) assembled by Marty P. Jordan and Matt Grossmann (2020) <http://ippsr.msu.edu/public-policy/correlates-state-policy> used by the cspp package. The Correlates data contains over 3000 variables across more than 100 years that pertain to state politics and policy in the United States.

Design, workflow and statistical analysis of Cluster Randomised Trials of (health) interventions where there may be spillover between the arms (see <https://thomasasmith.github.io/index.html>).

Optimization solver based on the Cross-Entropy method.

Computes solutions for linear and logistic regression models with potentially high-dimensional categorical predictors. This is done by applying a nonconvex penalty (SCOPE) and computing solutions in an efficient path-wise fashion. The scaling of the solution paths is selected automatically. Includes functionality for selecting tuning parameter lambda by k-fold cross-validation and early termination based on information criteria. Solutions are computed by cyclical block-coordinate descent, iterating an innovative dynamic programming algorithm to compute exact solutions for each block.