This package provides a quantile-quantile plot can be used to compare a sample of p-values to the uniform distribution. But when the dataset is big (i.e. > 1e4 p-values), plotting the quantile-quantile plot can be slow. geom_QQ uses all the data to calculate the quantiles, but thins it out in a way that focuses on points near zero before plotting to speed up plotting and decrease file size, when vector graphics are stored.

This package provides methods to test whether time series is consistent with white noise. Two new tests based on Haar wavelets and general wavelets described by Nason and Savchev (2014) <doi:10.1002/sta4.69> are provided and, for comparison purposes this package also implements the B test of Bartlett (1967) <doi:10.2307/2333850>. Functionality is provided to compute an approximation to the theoretical power of the general wavelet test in the case of general ARMA alternatives.

Carry out comparative authorship analysis of disputed and undisputed texts within the Likelihood Ratio Framework for expressing evidence in forensic science. This package contains implementations of well-known algorithms for comparative authorship analysis, such as Smith and Aldridge's (2011) Cosine Delta <doi:10.1080/09296174.2011.533591> or Koppel and Winter's (2014) Impostors Method <doi:10.1002/asi.22954>, as well as functions to measure their performance and to calibrate their outputs into Log-Likelihood Ratios.

This package implements the Model Context Protocol (MCP). Users can start R'-based servers, serving functions as tools for large language models to call before responding to the user in MCP-compatible apps like Claude Desktop and Claude Code', with options to run those tools inside of interactive R sessions. On the other end, when R is the client via the ellmer package, users can register tools from third-party MCP servers to integrate additional context into chats.

This package provides tools to solve real-world problems with multiple classes classifications by computing the areas under ROC and PR curve via micro-averaging and macro-averaging. The vignettes of this package can be found via <https://github.com/WandeRum/multiROC>. The methodology is described in V. Van Asch (2013) <https://www.clips.uantwerpen.be/~vincent/pdf/microaverage.pdf> and Pedregosa et al. (2011) <http://scikit-learn.org/stable/auto_examples/model_selection/plot_roc.html>.

This package provides tools to segment fire scars and assess severity and vegetation regeneration using Otsu thresholding on Relative Burn Ratio (RBR) and differenced Normalized Burn Ratio (dNBR) image composites. Includes support for mosaic handling, polygon metrics, post-fire regeneration detection, day-of-year flagging, and validation against reference datasets. Designed for analysis of fire history in the Iberian Peninsula. Input Landsat composites follow the methodology described in Quintero et al. (2025) <doi:10.2139/ssrn.4929831>.

Implementations of a large number of tests for symmetry and their bootstrap variants, which can be used for testing the symmetry of random samples around a known or unknown mean. Functions are also there for testing the symmetry of model residuals around zero. Currently, the supported models are linear models and generalized autoregressive conditional heteroskedasticity (GARCH) models (fitted with the fGarch package). All tests are implemented using the Rcpp package which ensures great performance of the code.

The total deviation index (TDI) is an unscaled statistical measure used to evaluate the deviation between paired quantitative measurements when assessing the extent of agreement between different raters. It describes a boundary such that a large specified proportion of the differences in paired measurements are within the boundary (Lin, 2000) <https://pubmed.ncbi.nlm.nih.gov/10641028/>. This R package implements some methodologies existing in the literature for TDI estimation and inference in the case of two raters.

This package provides a method to visualize pharmacometric analyses which are impacted by covariate effects. Variability-aligned covariate harmonized-effects and time-transformation equivalent ('vachette') facilitates intuitive overlays of data and model predictions, allowing for comprehensive comparison without dilution effects. vachette improves upon previous methods Lommerse et al. (2021) <doi:10.1002/psp4.12679>, enabling its application to all pharmacometric models and enhancing Visual Predictive Checks (VPC) by integrating data into cohesive plots that can highlight model misspecification.

Given a set of genomic sites/regions (e.g. ChIP-seq peaks, CpGs, differentially methylated CpGs or regions, SNPs, etc.) it is often of interest to investigate the intersecting genomic annotations. Such annotations include those relating to gene models (promoters, 5'UTRs, exons, introns, and 3'UTRs), CpGs (CpG islands, CpG shores, CpG shelves), or regulatory sequences such as enhancers. The annotatr package provides an easy way to summarize and visualize the intersection of genomic sites/regions with genomic annotations.

The package contains functions to infer and visualize cell cycle process using Single-cell RNA-Seq data. It exploits the idea of transfer learning, projecting new data to the previous learned biologically interpretable space. The tricycle provides a pre-learned cell cycle space, which could be used to infer cell cycle time of human and mouse single cell samples. In addition, it also offer functions to visualize cell cycle time on different embeddings and functions to build new reference.

This package provides a small collection of interesting and educational machine learning data sets which are used as examples in the mlr3 book Applied machine learning using mlr3 in R https://mlr3book.mlr-org.com, the use case gallery https://mlr3gallery.mlr-org.com, or in other examples. All data sets are properly preprocessed and ready to be analyzed by most machine learning algorithms. Data sets are automatically added to the dictionary of tasks if mlr3 is loaded.

This package provides portable tools to run system processes in the background. It can check if a background process is running; wait on a background process to finish; get the exit status of finished processes; kill background processes and their children; restart processes. It can read the standard output and error of the processes, using non-blocking connections. processx can poll a process for standard output or error, with a timeout. It can also poll several processes at once.

To implement disease ontology (DO) enrichment analysis, this package is designed and presents a double weighted model based on the latest annotations of the human genome with DO terms, by integrating the DO graph topology on a global scale. This package exhibits high accuracy that it can identify more specific DO terms, which alleviates the over enriched problem. The package includes various statistical models and visualization schemes for discovering the associations between genes and diseases from biological big data.

This package is a Shiny app for interactively analyzing and visualizing Nanostring GeoMX Whole Transcriptome Atlas data. Users have the option of exploring a sample data to explore this app's functionality. Regions of interest (ROIs) can be filtered based on any user-provided metadata. Upon taking two or more groups of interest, all pairwise and ANOVA-like testing are automatically performed. Available ouputs include PCA, Volcano plots, tables and heatmaps. Aesthetics of each output are highly customizable.

This package provides several methods for aggregating probabilistic forecasts. You have a group of people who have made probabilistic forecasts for the same event. You want to take advantage of the "wisdom of the crowd" and combine these forecasts in some sensible way. This package provides implementations of several strategies, including geometric mean of odds, an extremized aggregate (Neyman, Roughgarden (2021) <doi:10.1145/3490486.3538243>), and "high-density trimmed mean" (Powell et al. (2022) <doi:10.1037/dec0000191>).

Proposed by Harrell, the C index or concordance C, is considered an overall measure of discrimination in survival analysis between a survival outcome that is possibly right censored and a predictive-score variable, which can represent a measured biomarker or a composite-score output from an algorithm that combines multiple biomarkers. This package aims to statistically compare two C indices with right-censored survival outcome, which commonly arise from a paired design and thus resulting two correlated C indices.

This package provides methods and plotting functions for displaying categorical data on an interactive heatmap using plotly'. Provides functionality for strictly categorical heatmaps, heatmaps illustrating categorized continuous data and annotated heatmaps. Also, there are various options to interact with the x-axis to prevent overlapping axis labels, e.g. via simple sliders or range sliders. Besides the viewer pane, resulting plots can be saved as a standalone HTML file, embedded in R Markdown documents or in a Shiny app.

This package provides a simple algorithm to generate a continuous epidemiological week index from date variables in a dataframe. Weeks are computed as sequential 7-day intervals starting from the earliest observed date. They do not reset at calendar year boundaries and are not ISO 8601 nor MMWR calendar weeks. The approach is intended for epidemiological modeling and time-series analysis where temporal continuity is required. The generated weeks are sequential and do not reset at calendar year boundaries.

This package provides a lightweight fork of gMCP with functions for graphical described multiple test procedures introduced in Bretz et al. (2009) <doi:10.1002/sim.3495> and Bretz et al. (2011) <doi:10.1002/bimj.201000239>. Implements a flexible function using ggplot2 to create multiplicity graph visualizations. Contains instructions of multiplicity graph and graphical testing for group sequential design, described in Maurer and Bretz (2013) <doi:10.1080/19466315.2013.807748>, with necessary unit testing using testthat'.

Density function and generation of random variables from the Generalized Inverse Normal (GIN) distribution from Robert (1991) <doi:10.1016/0167-7152(91)90174-P>. Also provides density functions and generation from the GIN distribution truncated to positive or negative reals. Theoretical guarantees supporting the sampling algorithms and an application to Bayesian estimation of network formation models can be found in the working paper Ding, Estrada and Montoya-Blandón (2023) <https://www.smontoyablandon.com/publication/networks/network_externalities.pdf>.

An implementation of randomization-based hypothesis testing for three different estimands in a cluster-randomized encouragement experiment. The three estimands include (1) testing a cluster-level constant proportional treatment effect (Fisher's sharp null hypothesis), (2) pooled effect ratio, and (3) average cluster effect ratio. To test the third estimand, user needs to install Gurobi (>= 9.0.1) optimizer via its R API. Please refer to <https://www.gurobi.com/documentation/9.0/refman/ins_the_r_package.html>.

Semi-distance and mean-variance (MV) index are proposed to measure the dependence between a categorical random variable and a continuous variable. Test of independence and feature screening for classification problems can be implemented via the two dependence measures. For the details of the methods, see Zhong et al. (2023) <doi:10.1080/01621459.2023.2284988>; Cui and Zhong (2019) <doi:10.1016/j.csda.2019.05.004>; Cui, Li and Zhong (2015) <doi:10.1080/01621459.2014.920256>.

Calculates maximum likelihood estimate, exact and asymptotic confidence intervals, and exact and asymptotic goodness of fit p-values for concentration of infectious units from serial limiting dilution assays. This package uses the likelihood equation, exact goodness of fit p-values, and exact confidence intervals described in Meyers et al. (1994) <http://jcm.asm.org/content/32/3/732.full.pdf>. This software is also implemented as a web application through the Shiny R package <https://iupm.shinyapps.io/sldassay/>.