This package assists in demultiplexing scRNAseq data using both cell hashing and SNPs data. The SNP profile of each group os learned using high confidence assignments from the cell hashing data. Cells which cannot be assigned with high confidence from the cell hashing data are assigned to their most similar group based on their SNPs. We also provide some helper function to optimise SNP selection, create training data and merge SNP data into the SingleCellExperiment framework.

The missRows package implements the MI-MFA method to deal with missing individuals ('biological units') in multi-omics data integration. The MI-MFA method generates multiple imputed datasets from a Multiple Factor Analysis model, then the yield results are combined in a single consensus solution. The package provides functions for estimating coordinates of individuals and variables, imputing missing individuals, and various diagnostic plots to inspect the pattern of missingness and visualize the uncertainty due to missing values.

Explore calcium (Ca) and phosphate (Pi) homeostasis with two novel Shiny apps, building upon on a previously published mathematical model written in C, to ensure efficient computations. The underlying model is accessible here <https://pubmed.ncbi.nlm.nih.gov/28747359/)>. The first application explores the fundamentals of Ca-Pi homeostasis, while the second provides interactive case studies for in-depth exploration of the topic, thereby seeking to foster student engagement and an integrative understanding of Ca-Pi regulation.

Analysis of network community objects with applications to neuroimaging data. There are two main components to this package. The first is the hierarchical multimodal spinglass (HMS) algorithm, which is a novel community detection algorithm specifically tailored to the unique issues within brain connectivity. The other is a suite of semiparametric kernel machine methods that allow for statistical inference to be performed to test for potential associations between these community structures and an outcome of interest (binary or continuous).

This package creates a 3D data cube view of a RasterStack/Brick, typically a collection/array of RasterLayers (along z-axis) with the same geographical extent (x and y dimensions) and resolution, provided by package raster'. Slices through each dimension (x/y/z), freely adjustable in location, are mapped to the visible sides of the cube. The cube can be freely rotated. Zooming and panning can be used to focus on different areas of the cube.

Makes it easy to engage with the Application Program Interface (API) of the TCdata360 and Govdata360 platforms at <https://tcdata360.worldbank.org/> and <https://govdata360.worldbank.org/>, respectively. These application program interfaces provide access to over 5000 trade, competitiveness, and governance indicator data, metadata, and related information from sources both inside and outside the World Bank Group. Package functions include easier download of data sets, metadata, and related information, as well as searching based on user-inputted query.

An implementation of major general-purpose mechanisms for privatizing statistics, models, and machine learners, within the framework of differential privacy of Dwork et al. (2006) <doi:10.1007/11681878_14>. Example mechanisms include the Laplace mechanism for releasing numeric aggregates, and the exponential mechanism for releasing set elements. A sensitivity sampler (Rubinstein & Alda, 2017) <arXiv:1706.02562> permits sampling target non-private function sensitivity; combined with the generic mechanisms, it permits turn-key privatization of arbitrary programs.

Implementation of frequency tables and bar charts for qualitative variables and checkbox fields. This package implements tables and charts used in reports at Funarte (National Arts Foundation) and OBEC (Culture and Creative Economy Observatory) in Brazil, and its main purpose is to simplify the use of R for people with a background in the humanities and arts. Examples and details can be viewed in this presentation from 2026: <https://formacao2026.netlify.app/assets/modulo_3/modulo3#/title-slide>.

This package provides a quantile-quantile plot can be used to compare a sample of p-values to the uniform distribution. But when the dataset is big (i.e. > 1e4 p-values), plotting the quantile-quantile plot can be slow. geom_QQ uses all the data to calculate the quantiles, but thins it out in a way that focuses on points near zero before plotting to speed up plotting and decrease file size, when vector graphics are stored.

This package provides methods to test whether time series is consistent with white noise. Two new tests based on Haar wavelets and general wavelets described by Nason and Savchev (2014) <doi:10.1002/sta4.69> are provided and, for comparison purposes this package also implements the B test of Bartlett (1967) <doi:10.2307/2333850>. Functionality is provided to compute an approximation to the theoretical power of the general wavelet test in the case of general ARMA alternatives.

Carry out comparative authorship analysis of disputed and undisputed texts within the Likelihood Ratio Framework for expressing evidence in forensic science. This package contains implementations of well-known algorithms for comparative authorship analysis, such as Smith and Aldridge's (2011) Cosine Delta <doi:10.1080/09296174.2011.533591> or Koppel and Winter's (2014) Impostors Method <doi:10.1002/asi.22954>, as well as functions to measure their performance and to calibrate their outputs into Log-Likelihood Ratios.

Convert historical monetary values into their present-day equivalents using bundled CPI (Consumer Price Index) and GDP deflator data sourced from the World Bank Development Indicators. Supports British pounds (GBP), Australian dollars (AUD), US dollars (USD), Euro (EUR), Canadian dollars (CAD), Japanese yen (JPY), Chinese yuan (CNY), Swiss francs (CHF), New Zealand dollars (NZD), Indian rupees (INR), South Korean won (KRW), Brazilian reais (BRL), and Norwegian krone (NOK). Currency codes and country names are both accepted as input.

This package implements the Model Context Protocol (MCP). Users can start R'-based servers, serving functions as tools for large language models to call before responding to the user in MCP-compatible apps like Claude Desktop and Claude Code', with options to run those tools inside of interactive R sessions. On the other end, when R is the client via the ellmer package, users can register tools from third-party MCP servers to integrate additional context into chats.

This package provides tools to solve real-world problems with multiple classes classifications by computing the areas under ROC and PR curve via micro-averaging and macro-averaging. The vignettes of this package can be found via <https://github.com/WandeRum/multiROC>. The methodology is described in V. Van Asch (2013) <https://www.clips.uantwerpen.be/~vincent/pdf/microaverage.pdf> and Pedregosa et al. (2011) <http://scikit-learn.org/stable/auto_examples/model_selection/plot_roc.html>.

This package provides tools to segment fire scars and assess severity and vegetation regeneration using Otsu thresholding on Relative Burn Ratio (RBR) and differenced Normalized Burn Ratio (dNBR) image composites. Includes support for mosaic handling, polygon metrics, post-fire regeneration detection, day-of-year flagging, and validation against reference datasets. Designed for analysis of fire history in the Iberian Peninsula. Input Landsat composites follow the methodology described in Quintero et al. (2025) <doi:10.2139/ssrn.4929831>.

Implementations of a large number of tests for symmetry and their bootstrap variants, which can be used for testing the symmetry of random samples around a known or unknown mean. Functions are also there for testing the symmetry of model residuals around zero. Currently, the supported models are linear models and generalized autoregressive conditional heteroskedasticity (GARCH) models (fitted with the fGarch package). All tests are implemented using the Rcpp package which ensures great performance of the code.

The total deviation index (TDI) is an unscaled statistical measure used to evaluate the deviation between paired quantitative measurements when assessing the extent of agreement between different raters. It describes a boundary such that a large specified proportion of the differences in paired measurements are within the boundary (Lin, 2000) <https://pubmed.ncbi.nlm.nih.gov/10641028/>. This R package implements some methodologies existing in the literature for TDI estimation and inference in the case of two raters.

This package provides a method to visualize pharmacometric analyses which are impacted by covariate effects. Variability-aligned covariate harmonized-effects and time-transformation equivalent ('vachette') facilitates intuitive overlays of data and model predictions, allowing for comprehensive comparison without dilution effects. vachette improves upon previous methods Lommerse et al. (2021) <doi:10.1002/psp4.12679>, enabling its application to all pharmacometric models and enhancing Visual Predictive Checks (VPC) by integrating data into cohesive plots that can highlight model misspecification.

Given a set of genomic sites/regions (e.g. ChIP-seq peaks, CpGs, differentially methylated CpGs or regions, SNPs, etc.) it is often of interest to investigate the intersecting genomic annotations. Such annotations include those relating to gene models (promoters, 5'UTRs, exons, introns, and 3'UTRs), CpGs (CpG islands, CpG shores, CpG shelves), or regulatory sequences such as enhancers. The annotatr package provides an easy way to summarize and visualize the intersection of genomic sites/regions with genomic annotations.

The package contains functions to infer and visualize cell cycle process using Single-cell RNA-Seq data. It exploits the idea of transfer learning, projecting new data to the previous learned biologically interpretable space. The tricycle provides a pre-learned cell cycle space, which could be used to infer cell cycle time of human and mouse single cell samples. In addition, it also offer functions to visualize cell cycle time on different embeddings and functions to build new reference.

This package provides portable tools to run system processes in the background. It can check if a background process is running; wait on a background process to finish; get the exit status of finished processes; kill background processes and their children; restart processes. It can read the standard output and error of the processes, using non-blocking connections. processx can poll a process for standard output or error, with a timeout. It can also poll several processes at once.

This package provides a small collection of interesting and educational machine learning data sets which are used as examples in the mlr3 book Applied machine learning using mlr3 in R https://mlr3book.mlr-org.com, the use case gallery https://mlr3gallery.mlr-org.com, or in other examples. All data sets are properly preprocessed and ready to be analyzed by most machine learning algorithms. Data sets are automatically added to the dictionary of tasks if mlr3 is loaded.

To implement disease ontology (DO) enrichment analysis, this package is designed and presents a double weighted model based on the latest annotations of the human genome with DO terms, by integrating the DO graph topology on a global scale. This package exhibits high accuracy that it can identify more specific DO terms, which alleviates the over enriched problem. The package includes various statistical models and visualization schemes for discovering the associations between genes and diseases from biological big data.

This package is a Shiny app for interactively analyzing and visualizing Nanostring GeoMX Whole Transcriptome Atlas data. Users have the option of exploring a sample data to explore this app's functionality. Regions of interest (ROIs) can be filtered based on any user-provided metadata. Upon taking two or more groups of interest, all pairwise and ANOVA-like testing are automatically performed. Available ouputs include PCA, Volcano plots, tables and heatmaps. Aesthetics of each output are highly customizable.