Joint distribution of number of crossings and the longest run in a series of independent Bernoulli trials. The computations uses an iterative procedure where computations are based on results from shorter series. The procedure conditions on the start value and partitions by further conditioning on the position of the first crossing (or none).

This package provides a collection of tools to easily analyze clinical data, including functions for correlation analysis, and statistical testing. The package facilitates the integration of clinical metadata with other omics layers, enabling exploration of quantitative variables. It also includes the utility for frequency matching samples across a dataset based on patient variables.

Estimates a lasso penalized precision matrix via blockwise coordinate descent (BCD). This package is a simple wrapper around the popular glasso package and extends and enhances its capabilities. These enhancements include built-in cross validation and visualizations. See Friedman et al. (2008) <doi:10.1093/biostatistics/kxm045> for details regarding the estimation method.

This package provides routines for fitting Cox models by likelihood based boosting for single event survival data with right censoring or in the presence of competing risks. The methodology is described in Binder and Schumacher (2008) <doi:10.1186/1471-2105-9-14> and Binder et al. (2009) <doi:10.1093/bioinformatics/btp088>.

Providing a cluster allocation for n samples, either with an $n \times p$ data matrix or an $n \times n$ distance matrix, a bootstrap procedure is performed. The proportion of bootstrap replicates where a pair of samples cluster in the same cluster indicates who tightly the samples in a particular cluster clusters together.

This package provides a set of utility tools to inspect spatial objects, facilitate handling and reporting of topology errors and geometry validity issue with sp objects. Finally, it provides a geometry cleaner that will fix all geometry problems, and eliminate (at least reduce) the likelihood of having issues when doing spatial data processing.

Use emailjs API easily in R'. This package is not official. <https://www.emailjs.com/docs/rest-api/send/>. You can send e-mail with emailjs with function, based on httr'. You can also make a shiny ui and server function. It can be used for making feedback form, inquiry, and so on.

Calculates the cost of crossing in terms of the number of individuals and generations, which is theoretically formulated by Servin et al. (2004) <DOI:10.1534/genetics.103.023358>. This package has been designed for selecting appropriate parental genotypes and find the most efficient crossing scheme for gene pyramiding, especially for plant breeding.

Imputation (replacement) of missing values in univariate time series. Offers several imputation functions and missing data plots. Available imputation algorithms include: Mean', LOCF', Interpolation', Moving Average', Seasonal Decomposition', Kalman Smoothing on Structural Time Series models', Kalman Smoothing on ARIMA models'. Published in Moritz and Bartz-Beielstein (2017) <doi:10.32614/RJ-2017-009>.

Generates three inter-related genomic datasets: methylation, gene expression and protein expression having user specified cluster patterns. The simulation utilizes the realistic inter- and intra- relationships from real DNA methylation, mRNA expression and protein expression data from the TCGA ovarian cancer study, Chalise (2016) <doi:10.1016/j.cmpb.2016.02.011>.

An adaption of the consensus clustering approach from ConsensusClusterPlus for longitudinal data. The longitudinal data is clustered with flexible mixture models from flexmix', while the consensus matrices are hierarchically clustered as in ConsensusClusterPlus'. By using the flexibility from flexmix and FactoMineR', one can use mixed data types for the clustering.

Principal component analysis (PCA) is one of the most widely used data analysis techniques. This package provides a series of vignettes explaining PCA starting from basic concepts. The primary purpose is to serve as a self-study resource for anyone wishing to understand PCA better. A few convenience functions are provided as well.

Supplies a LazyData facility for packages which have data sets but do not provide LazyData: true. A single function is is included, requireData, which is a drop-in replacement for base::require, but carrying the additional functionality. By default, it suppresses package startup messages as well. See argument reallyQuitely'.

This package provides functions for multivariate and propensity score matching and for finding optimal balance based on a genetic search algorithm. A variety of univariate and multivariate metrics to determine if balance has been obtained are also provided. For details, see the paper by Jasjeet Sekhon (2007, <doi:10.18637/jss.v042.i07>).

This package provides functions for calculating the point and interval estimates of the natural indirect effect (NIE), total effect (TE), and mediation proportion (MP), based on the product approach. We perform the methods considered in Cheng, Spiegelman, and Li (2021) Estimating the natural indirect effect and the mediation proportion via the product method.

This package implements Progressive Regularized Vine Copula (Prog-Vine) frameworks for high-dimensional dependent competing risks with masked failure causes under Progressive Type-II Censoring. Fits Weibull marginals, estimates pair-copula trees using Expectation-Maximization (EM) algorithms, computes Louis observed information confidence intervals, and implements Data Augmentation Gibbs Samplers for Bayesian credible intervals.

Quantitative trait loci (QTL) analysis and exploration of meiotic patterns in autopolyploid bi-parental F1 populations. For all ploidy levels, identity-by-descent (IBD) probabilities can be estimated. Significance thresholds, exploring QTL allele effects and visualising results are provided. For more background and to reference the package see <doi:10.1093/bioinformatics/btab574>.

This package provides stability selection with Lasso and two diagnostic plots for assessing selection stability. The Regustab plot shows stability across the regularisation parameter grid, while the Convstab plot shows stability as a function of the number of subsamples. Methods are described in Nouraie and Muller (2026) <doi:10.1080/03610926.2026.2715517>.

This package provides flexible hazard ratio curves allowing non-linear relationships between continuous predictors and survival. To better understand the effects that each continuous covariate has on the outcome, results are expressed in terms of hazard ratio curves, taking a specific covariate value as reference. Confidence bands for these curves are also derived.

Renders plots to a temporary image using the ragg graphics device and returns knitr::include_graphics() output. Optionally saves the image to a specified path. This helps ensure consistent appearance across interactive sessions, saved files, and knitted documents. For more details see Pedersen and Shemanarev (2025) <doi: 10.32614/CRAN.package.ragg>.

Implementation of small area estimation using Hierarchical Bayesian (HB) Method when auxiliary variable measured with error. The rjags package is employed to obtain parameter estimates. For the references, see Rao and Molina (2015) <doi:10.1002/9781118735855>, Ybarra and Lohr (2008) <doi:10.1093/biomet/asn048>, and Ntzoufras (2009, ISBN-10: 1118210352).

This package provides a comprehensive suite of functions designed for constructing and managing ShinyItemAnalysis modules, supplemented with detailed guides, ready-to-use templates, linters, and tests. This package allows developers to seamlessly create and integrate one or more modules into their existing packages or to start a new module project from scratch.

Stores the data associated with your amplicon sequence analysis. This includes nucleotide sequences, abundance, sample and treatment assignments, taxonomic classifications, asv, otu and phylotype clusters, metadata, trees and various reports. It is designed to facilitate data analysis across multiple R packages with utility functions to read / write from mothur', qiime2', dada2', and phyloseq'.

This package provides a set of functions to: (1) perform fuzzy clustering of vegetation data (De Caceres et al, 2010) <doi:10.1111/j.1654-1103.2010.01211.x>; (2) to assess ecological community similarity on the basis of structure and composition (De Caceres et al, 2013) <doi:10.1111/2041-210X.12116>.