The knockoff filter is a general procedure for controlling the false discovery rate (FDR) when performing variable selection. For more information, see the website below and the accompanying paper: Candes et al., "Panning for gold: model-X knockoffs for high-dimensional controlled variable selection", J. R. Statist. Soc. B (2018) 80, 3, pp. 551-577.
Linear dimension reduction subspaces can be uniquely defined using orthogonal projection matrices. This package provides tools to compute distances between such subspaces and to compute the average subspace. For details see Liski, E.Nordhausen K., Oja H., Ruiz-Gazen A. (2016) Combining Linear Dimension Reduction Subspaces <doi:10.1007/978-81-322-3643-6_7>.
An implementation of the Nonparametric Predictive Inference approach in R. It provides tools for quantifying uncertainty via lower and upper probabilities. It includes useful functions for pairwise and multiple comparisons: comparing two groups with and without terminated tails, selecting the best group, selecting the subset of best groups, selecting the subset including the best group.
This package provides a dynamic timer control (DTC) is a shiny widget that enables time-based processes in applications. It allows users to execute these processes manually in individual steps or at customizable speeds. The timer can be paused, resumed, or restarted. This control is particularly well-suited for simulations, animations, countdowns, or interactive visualizations.
Standard error adjusted adaptive lasso (SEA-lasso) is a version of the adaptive lasso, which incorporates OLS standard error to the L1 penalty weight. This method is intended for variable selection under linear regression settings (n > p). This new weight assignment strategy is especially useful when the collinearity of the design matrix is a concern.
The implementation to perform the geometric spatial point analysis developed in Hernández & Solàs (2022) <doi:10.1007/s00180-022-01244-1>. It estimates the geometric goodness-of-fit index for a set of variables against a response one based on the sf package. The package has methods to print and plot the results.
Projection pursuit is used to find interesting low-dimensional projections of high-dimensional data by optimizing an index over all possible projections. The spinebil package contains methods to evaluate the performance of projection pursuit index functions using tour methods. A paper describing the methods can be found at <doi:10.1007/s00180-020-00954-8>.
Sensitivity analysis in unmatched observational studies, with or without strata. The main functions are sen2sample() and senstrat(). See Rosenbaum, P. R. and Krieger, A. M. (1990), JASA, 85, 493-498, <doi:10.1080/01621459.1990.10476226> and Gastwirth, Krieger and Rosenbaum (2000), JRSS-B, 62, 545â 555 <doi:10.1111/1467-9868.00249> .
Inference on panel data using spatiotemporal partially-observed Markov process (SpatPOMP) models. The spatPomp package extends pomp to include algorithms taking advantage of the spatial structure in order to assist with handling high dimensional processes. See Asfaw et al. (2024) <doi:10.48550/arXiv.2101.01157> for further description of the package.
Datasets detailing the results, castaways, and events of each season of Survivor for the US, Australia, South Africa, New Zealand, and the UK. This includes details on the cast, voting history, immunity and reward challenges, jury votes, boot order, advantage details, and episode ratings. Use this for analysis of trends and statistics of the game.
Improves the predictive performance of ridge and lasso regression exploiting one or more sources of prior information on the importance and direction of effects (Rauschenberger and others 2023, <doi:10.1093/bioinformatics/btad680>). For running the vignette (optional), install fwelnet and ecpc from <https://github.com/kjytay/fwelnet> and <https://github.com/Mirrelijn/ecpc>, respectively.
This package provides access to the complete Pali Canon, or Tipitaka, the canonical scripture for Theravadin Buddhists worldwide. Based on the Chattha Sangayana Tipitaka version 4 (Vipassana Research Institute, 1990). Includes word frequency data and tools for Pali string sorting. For a lemmatized critical edition with sutta-level granularity, see the companion package tipitaka.critical'.
This package provides an interactive wrapper for the tmpinv() function from the rtmpinv package with options extending its functionality to pre- and post-estimation processing and streamlined incorporation of prior cell information. The Tabular Matrix Problems via Pseudoinverse Estimation (TMPinv) is a two-stage estimation method that reformulates structured table-based systems - such as allocation problems, transaction matrices, and input-output tables - as structured least-squares problems. Based on the Convex Least Squares Programming (CLSP) framework, TMPinv solves systems with row and column constraints, block structure, and optionally reduced dimensionality by (1) constructing a canonical constraint form and applying a pseudoinverse-based projection, followed by (2) a convex-programming refinement stage to improve fit, coherence, and regularization (e.g., via Lasso, Ridge, or Elastic Net).
This package aims to bring the power and flexibility of AnnData to the R ecosystem, allowing you to effortlessly manipulate and analyze your single-cell data. This package lets you work with backed h5ad and zarr files, directly access various slots (e.g. X, obs, var), or convert the data into SingleCellExperiment and Seurat objects.
This package provides tools to import transcript-level abundance, estimated counts and transcript lengths, and to summarize them into matrices for use with downstream gene-level analysis packages. Average transcript length, weighted by sample-specific transcript abundance estimates, is provided as a matrix which can be used as an offset for different expression of gene-level counts.
This package contains methods for converting standard objects constructed by bioinformatics packages, especially those in Bioconductor, and converting them to tidy data. It thus serves as a complement to the broom package, and follows the same tidy, augment, glance division of tidying methods. Tidying data makes it easy to recombine, reshape and visualize bioinformatics analyses.
This package provides flexible parametric models for time-to-event data, including the Royston-Parmar spline model, generalized gamma and generalized F distributions. Any user-defined parametric distribution can be fitted, given at least an R function defining the probability density or hazard. There are also tools for fitting and predicting from fully parametric multi-state models.
Tool to help debug / hack at the BCM283x GPIO. You can dump the state of a GPIO (or all GPIOs). You can change a GPIO mode and pulls (and level, if set as an output). Beware that this tool writes directly to the BCM283x GPIO registers, ignoring anything else that may be using them (like Linux drivers).
Open Cancer TherApeutic Discovery (OCTAD) package implies sRGES approach for the drug discovery. The essential idea is to identify drugs that reverse the gene expression signature of a disease by tamping down over-expressed genes and stimulating weakly expressed ones. The following package contains all required precomputed data for whole OCTAD pipeline computation.
Multivariate tools to analyze comparative data, i.e. a phylogeny and some traits measured for each taxa. The package contains functions to represent comparative data, compute phylogenetic proximities, perform multivariate analysis with phylogenetic constraints and test for the presence of phylogenetic autocorrelation. The package is described in Jombart et al (2010) <doi:10.1093/bioinformatics/btq292>.
This package provides a WebSocket-based implementation of the automerge-repo synchronization protocol used by sync.automerge.org'. Acts as a sync server, enabling R to serve as a synchronization hub for Automerge clients in JavaScript', Rust', and other languages, and as a client for fetching, editing, and synchronizing documents hosted on remote servers.
Animation of observed trajectories using spline-based interpolation (see for example, Buderman, F. E., Hooten, M. B., Ivan, J. S. and Shenk, T. M. (2016), <doi:10.1111/2041-210X.12465> "A functional model for characterizing long-distance movement behaviour". Methods Ecol Evol). Intended to be used exploratory data analysis, and perhaps for preparation of presentations.
This contains helpful functions for parsing, managing, plotting, and visualizing activities, most often from GPX (GPS Exchange Format) files recorded by GPS devices. It allows easy parsing of the source files into standard R data formats, along with functions to compute derived data for the activity, and to plot the activity in a variety of ways.
This package provides tools to generate unique identifier codes and printable barcoded labels for the management of biological samples. The creation of unique ID codes and printable PDF files can be initiated by standard commands, user prompts, or through a GUI addin for R Studio. Biologically informative codes can be included for hierarchically structured sampling designs.