This package provides a set of functions to extract results from regression models and plot the effect size using ggplot2 seamlessly. While broom is useful to convert statistical analysis objects into tidy data frames, coefplot is adept at showing multivariate regression results. With specific outcome, this package could build regression models automatically, extract results into a data frame and provide a quicker way to summarize models statistical findings using ggplot2'.

Provide estimation and data generation tools for the skew-unit family discussed based on Mukhopadhyay and Brani (1995) <doi:10.2307/2348710>. The family contains extensions for popular distributions such as the ArcSin discussed in Arnold and Groeneveld (1980) <doi:10.1080/01621459.1980.10477449>, triangular, U-quadratic and Johnson-SB proposed in Cortina-Borja (2006) <doi:10.1111/j.1467-985X.2006.00446_12.x> distributions, among others.

This package provides a very nice interface to Princeton's WordNet without rJava dependency. WordNet data is not included. Princeton University makes WordNet available to research and commercial users free of charge provided the terms of their license (<https://wordnet.princeton.edu/license-and-commercial-use>) are followed, and proper reference is made to the project using an appropriate citation (<https://wordnet.princeton.edu/citing-wordnet>).

This package provides a novel spatial topic model to integrate both cell type and spatial information to identify the complex spatial tissue architecture on multiplexed tissue images without human intervention. The Package implements a collapsed Gibbs sampling algorithm for inference. SpaTopic is scalable to large-scale image datasets without extracting neighborhood information for every single cell. For more details on the methodology, see <https://xiyupeng.github.io/SpaTopic/>.

This package provides a general framework for statistical simulation, which allows researchers to make use of a wide range of simulation designs with minimal programming effort. The package provides functionality for drawing samples from a distribution or a finite population, for adding outliers and missing values, as well as for visualization of the simulation results. It follows a clear object-oriented design and supports parallel computing to increase computational performance.

Includes built-in methods for generating long SQL CASE statements, and other SQL statements that may otherwise be arduous to construct by hand. The generated statement can easily be concatenated to string literals to form queries to SQL'-like databases, such as when using the RODBC package. The current methods include casewhen() for building CASE statements, inlist() for building IN statements, and updatetable() for building UPDATE statements.

Identification of aberrant gene expression in RNA-seq data. Read count expectations are modeled by an autoencoder to control for confounders in the data. Given these expectations, the RNA-seq read counts are assumed to follow a negative binomial distribution with a gene-specific dispersion. Outliers are then identified as read counts that significantly deviate from this distribution. Furthermore, OUTRIDER provides useful plotting functions to analyze and visualize the results.

Starting from one SBML file, it extracts information from each listOfCompartments, listOfSpecies and listOfReactions element by saving them into data frames. Each table provides one row for each entity (i.e. either compartment, species, reaction or speciesReference) and one set of columns for the attributes, one column for the content of the notes subelement and one set of columns for the content of the annotation subelement.

This package provides a lightweight but powerful R interface to the Azure Resource Manager REST API. The package exposes a comprehensive class framework and related tools for creating, updating and deleting Azure resource groups, resources and templates. While AzureRMR can be used to manage any Azure service, it can also be extended by other packages to provide extra functionality for specific services. Part of the AzureR family of packages.

Implementation of the bunching estimator for kinks and notches. Allows for flexible estimation of counterfactual (e.g. controlling for round number bunching, accounting for other bunching masses within bunching window, fixing bunching point to be minimum, maximum or median value in its bin, etc.). It produces publication-ready plots in the style followed since Chetty et al. (2011) <doi:10.1093/qje/qjr013>, with lots of functionality to set plot options.

Fit Bayesian models using brms'/'Stan with parsnip'/'tidymodels via bayesian <doi:10.5281/zenodo.4426836>. tidymodels is a collection of packages for machine learning; see Kuhn and Wickham (2020) <https://www.tidymodels.org>). The technical details of brms and Stan are described in Bürkner (2017) <doi:10.18637/jss.v080.i01>, Bürkner (2018) <doi:10.32614/RJ-2018-017>, and Carpenter et al. (2017) <doi:10.18637/jss.v076.i01>.

This package provides functions to align curves and to compute mean curves based on the elastic distance defined in the square-root-velocity framework. For more details on this framework see Srivastava and Klassen (2016, <doi:10.1007/978-1-4939-4020-2>). For more theoretical details on our methods and algorithms see Steyer et al. (2023, <doi:10.1111/biom.13706>) and Steyer et al. (2023, <arXiv:2305.02075>).

Estimates and provides inference for quantities that assess high dimensional mediation and potential surrogate markers including the direct effect of treatment, indirect effect of treatment, and the proportion of treatment effect explained by a surrogate/mediator; details are described in Zhou et al (2022) <doi:10.1002/sim.9352> and Zhou et al (2020) <doi:10.1093/biomet/asaa016>. This package relies on the optimization software MOSEK', <https://www.mosek.com>.

The genridge package introduces generalizations of the standard univariate ridge trace plot used in ridge regression and related methods. These graphical methods show both bias (actually, shrinkage) and precision, by plotting the covariance ellipsoids of the estimated coefficients, rather than just the estimates themselves. 2D and 3D plotting methods are provided, both in the space of the predictor variables and in the transformed space of the PCA/SVD of the predictors.

This algorithm is described in detail in the paper "Hedging Forecast Combinations With an Application to the Random Forest" by Beck et al. (2024) <https://papers.ssrn.com/sol3/papers.cfm?abstract_id=5032102>. The package provides a function hedgedrf() that can be used to train a Hedged Random Forest model on a dataset, and a function predict.hedgedrf() that can be used to make predictions with the model.

The wiDB...() functions provide an interface to the public API of the wiDB <https://github.com/SPATIAL-Lab/isoWater/blob/master/Protocol.md>: build, check and submit queries, and receive and unpack responses. Data analysis functions support Bayesian inference of the source and source isotope composition of water samples that may have experienced evaporation. Algorithms adapted from Bowen et al. (2018, <doi:10.1007/s00442-018-4192-5>).

The app will calculate the ICER (incremental cost-effectiveness ratio) Rawlins (2012) <doi:10.1016/B978-0-7020-4084-9.00044-6> from the mean costs and quality-adjusted life years (QALY) Torrance and Feeny (2009) <doi:10.1017/S0266462300008461> for a set of treatment options, and draw the efficiency frontier in the costs-effectiveness plane. The app automatically identifies and excludes dominated and extended-dominated options from the ICER calculation.

Variational Expectation-Maximization algorithm to fit the noisy stochastic block model to an observed dense graph and to perform a node clustering. Moreover, a graph inference procedure to recover the underlying binary graph. This procedure comes with a control of the false discovery rate. The method is described in the article "Powerful graph inference with false discovery rate control" by T. Rebafka, E. Roquain, F. Villers (2020) <arXiv:1907.10176>.

Simplifies MCMC setup by automatically looping through sampling functions and saving the results. Reduces the memory footprint of running MCMC and saves samples to disk as the chain runs. Allows samples from the chain to be analyzed while the MCMC is still running. Provides functions for commonly performed operations such as calculating Metropolis acceptance ratios and creating adaptive Metropolis samplers. References: Roberts and Rosenthal (2009) <doi:10.1198/jcgs.2009.06134>.

This package provides functions to compute split generalized linear models. The approach fits generalized linear models that split the covariates into groups. The optimal split of the variables into groups and the regularized estimation of the coefficients are performed by minimizing an objective function that encourages sparsity within each group and diversity among them. Example applications can be found in Christidis et al. (2021) <doi:10.48550/arXiv.2102.08591>.

This package provides a Package for selecting variables for the joint modeling of mean and dispersion (including models for mixture experiments) based on hypothesis testing and the quality of model's fit. In each iteration of the selection process, a criterion for checking the goodness of fit is used as a filter for choosing the terms that will be evaluated by a hypothesis test. Pinto & Pereira (2021) <arXiv:2109.07978>.

Complete work flow for the analysis of pharmacokinetic pharmacodynamic (PKPD), physiologically-based pharmacokinetic (PBPK) and systems pharmacology models including: creation of ordinary differential equation-based models, pooled parameter estimation, individual/population based simulations, rule-based simulations for clinical trial design and modeling assays, deployment with a customizable Shiny app, and non-compartmental analysis. System-specific analysis templates can be generated and each element includes integrated reporting with PowerPoint and Word'.

Perform the analysis of the World Health Organization (WHO) Pharmacovigilance database VigiBase (Extract Case Level version), <https://who-umc.org/> e.g., load data, perform data management, disproportionality analysis, and descriptive statistics. Intended for pharmacovigilance routine use or studies. This package is NOT supported nor reflect the opinion of the WHO, or the Uppsala Monitoring Centre. Disproportionality methods are described by Norén et al (2013) <doi:10.1177/0962280211403604>.

This package provides a multi-objective optimization algorithm for disease sub-type discovery based on a non-dominated sorting genetic algorithm. The Galgo framework combines the advantages of clustering algorithms for grouping heterogeneous omics data and the searching properties of genetic algorithms for feature selection. The algorithm search for the optimal number of clusters determination considering the features that maximize the survival difference between sub-types while keeping cluster consistency high.