The standard Difference-in-Differences (DID) setup involves two periods and two groups -- a treated group and untreated group. Many applications of DID methods involve more than two periods and have individuals that are treated at different points in time. This package contains tools for computing average treatment effect parameters in Difference in Differences setups with more than two periods and with variation in treatment timing using the methods developed in Callaway and Sant'Anna (2021) <doi:10.1016/j.jeconom.2020.12.001>. The main parameters are group-time average treatment effects which are the average treatment effect for a particular group at a a particular time. These can be aggregated into a fewer number of treatment effect parameters, and the package deals with the cases where there is selective treatment timing, dynamic treatment effects, calendar time effects, or combinations of these. There are also functions for testing the Difference in Differences assumption, and plotting group-time average treatment effects.

Implementation of the double/debiased machine learning framework of Chernozhukov et al. (2018) <doi:10.1111/ectj.12097> for partially linear regression models, partially linear instrumental variable regression models, interactive regression models and interactive instrumental variable regression models. DoubleML allows estimation of the nuisance parts in these models by machine learning methods and computation of the Neyman orthogonal score functions. DoubleML is built on top of mlr3 and the mlr3 ecosystem. The object-oriented implementation of DoubleML based on the R6 package is very flexible. More information available in the publication in the Journal of Statistical Software: <doi:10.18637/jss.v108.i03>.

This package provides statistical tests and support functions for detecting irregular digit patterns in numerical data. The package includes tools for extracting digits at various locations in a number, tests for repeated values, and (Bayesian) tests of digit distributions.

Generates simulated data representing the LOX drop testing process (also known as impact testing). A simulated process allows for accelerated study of test behavior. Functions are provided to simulate trials, test series, and groups of test series. Functions for creating plots specific to this process are also included. Test attributes and criteria can be set arbitrarily. This work is not endorsed by or affiliated with NASA. See "ASTM G86-17, Standard Test Method for Determining Ignition Sensitivity of Materials to Mechanical Impact in Ambient Liquid Oxygen and Pressurized Liquid and Gaseous Oxygen Environments" <doi:10.1520/G0086-17>.

Double constrained correspondence analysis (dc-CA) analyzes (multi-)trait (multi-)environment ecological data by using the vegan package and native R code. Throughout the two step algorithm of ter Braak et al. (2018) is used. This algorithm combines and extends community- (sample-) and species-level analyses, i.e. the usual community weighted means (CWM)-based regression analysis and the species-level analysis of species-niche centroids (SNC)-based regression analysis. The two steps use canonical correspondence analysis to regress the abundance data on to the traits and (weighted) redundancy analysis to regress the CWM of the orthonormalized traits on to the environmental predictors. The function dc_CA() has an option to divide the abundance data of a site by the site total, giving equal site weights. This division has the advantage that the multivariate analysis corresponds with an unweighted (multi-trait) community-level analysis, instead of being weighted. The first step of the algorithm uses vegan::cca(). The second step uses wrda() but vegan::rda() if the site weights are equal. This version has a predict() function. For details see ter Braak et al. 2018 <doi:10.1007/s10651-017-0395-x>. and ter Braak & van Rossum 2025 <doi:10.1016/j.ecoinf.2025.103143>.

Functionality for analyzing dose-volume histograms (DVH) in radiation oncology: Read DVH text files, calculate DVH metrics as well as generalized equivalent uniform dose (gEUD), biologically effective dose (BED), equivalent dose in 2 Gy fractions (EQD2), normal tissue complication probability (NTCP), and tumor control probability (TCP). Show DVH diagrams, check and visualize quality assurance constraints for the DVH. Includes web-based graphical user interface.

Scripting of structural equation models via lavaan for Dyadic Data Analysis, and helper functions for supplemental calculations, tabling, and model visualization. Current models supported include Dyadic Confirmatory Factor Analysis, the Actorâ Partner Interdependence Model (observed and latent), the Common Fate Model (observed and latent), Mutual Influence Model (latent), and the Bifactor Dyadic Model (latent).

Dynamic Reservoir Simulation Model (DYRESM) and Computational Aquatic Ecosystem Dynamics Model (CAEDYM) model development, including assisting with calibrating selected model parameters and visualising model output through time series plot, profile plot, contour plot, and scatter plot. For more details, see Yu et al. (2023) <https://journal.r-project.org/articles/RJ-2023-008/>.

To calculate the sensitivity and specificity in the absence of gold standard using the Bayesian method. The Bayesian method can be referenced at Haiyan Gu and Qiguang Chen (1999) <doi:10.3969/j.issn.1002-3674.1999.04.004>.

Algorithms implementing populations of agents that interact with one another and sense their environment may exhibit emergent behavior such as self-organization and swarm intelligence. Here, a swarm system called Databionic swarm (DBS) is introduced which was published in Thrun, M.C., Ultsch A.: "Swarm Intelligence for Self-Organized Clustering" (2020), Artificial Intelligence, <DOI:10.1016/j.artint.2020.103237>. DBS is able to adapt itself to structures of high-dimensional data such as natural clusters characterized by distance and/or density based structures in the data space. The first module is the parameter-free projection method called Pswarm (Pswarm()), which exploits the concepts of self-organization and emergence, game theory, swarm intelligence and symmetry considerations. The second module is the parameter-free high-dimensional data visualization technique, which generates projected points on the topographic map with hypsometric tints defined by the generalized U-matrix (GeneratePswarmVisualization()). The third module is the clustering method itself with non-critical parameters (DBSclustering()). Clustering can be verified by the visualization and vice versa. The term DBS refers to the method as a whole. It enables even a non-professional in the field of data mining to apply its algorithms for visualization and/or clustering to data sets with completely different structures drawn from diverse research fields. The comparison to common projection methods can be found in the book of Thrun, M.C.: "Projection Based Clustering through Self-Organization and Swarm Intelligence" (2018) <DOI:10.1007/978-3-658-20540-9>.

Implementation of the Density Ratio Permutation Test for testing the goodness-of-fit of a hypothesised ratio of two densities, as described in Bordino and Berrett (2025) <doi:10.48550/arXiv.2505.24529>.

This package provides data transformations, estimation utilities, predictive evaluation measures and simulation functions for discrete time survival analysis.

For estimation of a variable of interest using Kalman filter by incorporating results from previous assessments, i.e. through development weighted estimates where weights are assigned inversely proportional to the variance of existing and new estimates. For reference see Ehlers et al. (2017) <doi:10.20944/preprints201710.0098.v1>.

Produce publication quality graphics from output of GGobi describe display plugin.

Tests whether multivariate ordinal data may stem from discretizing a multivariate normal distribution. The test is described by Foldnes and Grønneberg (2019) <doi:10.1080/10705511.2019.1673168>. In addition, an adjusted polychoric correlation estimator is provided that takes marginal knowledge into account, as described by Grønneberg and Foldnes (2022) <doi:10.1037/met0000495>.

Computations of Fisher's z-tests concerning different kinds of correlation differences. The diffpwr family entails approaches to estimating statistical power via Monte Carlo simulations. Important to note, the Pearson correlation coefficient is sensitive to linear association, but also to a host of statistical issues such as univariate and bivariate outliers, range restrictions, and heteroscedasticity (e.g., Duncan & Layard, 1973 <doi:10.1093/BIOMET/60.3.551>; Wilcox, 2013 <doi:10.1016/C2010-0-67044-1>). Thus, every power analysis requires that specific statistical prerequisites are fulfilled and can be invalid if the prerequisites do not hold. To this end, the bootcor family provides bootstrapping confidence intervals for the incorporated correlation difference tests.

Construction and analysis of matrix population models in R.

This package provides functions to accompany Wayne W. Daniel's Biostatistics: A Foundation for Analysis in the Health Sciences, Tenth Edition.

This package provides a comprehensive visualization toolkit built with coders of all skill levels and color-vision impaired audiences in mind. It allows creation of finely-tuned, publication-quality figures from single function calls. Visualizations include scatter plots, compositional bar plots, violin, box, and ridge plots, and more. Customization ranges from size and title adjustments to discrete-group circling and labeling, hidden data overlay upon cursor hovering via ggplotly() conversion, and many more, all with simple, discrete inputs. Color blindness friendliness is powered by legend adjustments (enlarged keys), and by allowing the use of shapes or letter-overlay in addition to the carefully selected dittoColors().

Differential Analysis of short RNA transcripts that can be modeled by either Poisson or Negative binomial distribution. The statistical methodology implemented in this package is based on the random selection of references genes (Desaulle et al. (2021) <arXiv:2103.09872>).

This package provides robustness checks driven by directed acyclic graphs (DAGs). Given a dagitty DAG object and a model specification, DAGassist classifies variables by causal roles, flags problematic controls, and generates a report comparing the original model with minimal and canonical adjustment sets. Exports publication-grade reports in LaTeX', Word', Excel', or plain text. DAGassist is built on dagitty', an R package that uses the DAGitty web tool (<https://dagitty.net/>) for creating and analyzing DAGs. Methods draw on Pearl (2009) <doi:10.1017/CBO9780511803161> and Textor et al. (2016) <doi:10.1093/ije/dyw341>.

The load estimation method is based on a general factor model to solve the estimates of load and specific variance. The philosophy of the package is described in Guangbao Guo. (2022). <doi:10.1007/s00180-022-01270-z>.

Allows users to quickly and easily detect data containing Personally Identifiable Information (PII) through convenience functions.

Statistical inference for the regression coefficients in high-dimensional linear models with hidden confounders. The Doubly Debiased Lasso method was proposed in <arXiv:2004.03758>.