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Analyses gene expression data derived from experiments to detect differentially expressed genes by employing the concept of majority voting with five different statistical models. It includes functions for differential expression analysis, significance testing, etc. It simplifies the process of uncovering meaningful patterns and trends within gene expression data, aiding researchers in downstream analysis. Boyer, R.S., Moore, J.S. (1991) <doi:10.1007/978-94-011-3488-0_5>.
Data screening is an important first step of any statistical analysis. dataMaid auto generates a customizable data report with a thorough summary of the checks and the results that a human can use to identify possible errors. It provides an extendable suite of test for common potential errors in a dataset.
This package creates discretised versions of continuous distribution functions by mapping continuous values to an underlying discrete grid, based on a (uniform) frequency of discretisation, a valid discretisation point, and an integration range. For a review of discretisation methods, see Chakraborty (2015) <doi:10.1186/s40488-015-0028-6>.
This package implements a likelihood-based method for genome polarization, identifying which alleles of SNV markers belong to either side of a barrier to gene flow. The approach co-estimates individual assignment, barrier strength, and divergence between sides, with direct application to studies of hybridization. Includes VCF-to-diem conversion and input checks, support for mixed ploidy and parallelization, and tools for visualization and diagnostic outputs. Based on diagnostic index expectation maximization as described in Baird et al. (2023) <doi:10.1111/2041-210X.14010>.
This package implements the deflist class, a read-only list-like object that accesses its elements via a function. The deflist class can be used to model deferred access to data or computations by routing indexed list access to a function. This approach is particularly useful when sequential list-like access to data is required but holding all the data in memory at once is not feasible. The package also provides utilities for memoisation and caching to optimize access to frequently requested elements.
This package provides several data sets for use with discrete statistical tests and discrete multiple testing procedures. Some of them are also available as a four-column version, so that each row represents a 2x2 table.
Extremely fast and memory efficient computation of the DER (or PaF) income polarization index as proposed by Duclos J. Y., Esteban, J. and Ray D. (2004). "Polarization: concepts, measurement, estimation". Econometrica, 72(6): 1737--1772. <doi:10.1111/j.1468-0262.2004.00552.x>. The index may be computed for a single or for a range of values of the alpha-parameter and bootstrapping is also available.
Extends package distr by functionals, distances, and conditional distributions.
Data cleaning scripts typically contain a lot of if this change that type of statements. Such statements are typically condensed expert knowledge. With this package, such data modifying rules are taken out of the code and become in stead parameters to the work flow. This allows one to maintain, document, and reason about data modification rules as separate entities.
Spatial analyses involving binning require that every bin have the same area, but this is impossible using a rectangular grid laid over the Earth or over any projection of the Earth. Discrete global grids use hexagons, triangles, and diamonds to overcome this issue, overlaying the Earth with equally-sized bins. This package provides utilities for working with discrete global grids, along with utilities to aid in plotting such data.
Integrated differential expression (DE) and differential co-expression (DC) analysis on gene expression data based on DECODE (DifferEntial CO-expression and Differential Expression) algorithm.
DataSHIELD is an infrastructure and series of R packages that enables the remote and non-disclosive analysis of sensitive research data. This package is the DataSHIELD interface implementation to analyze data shared on a MOLGENIS Armadillo server. MOLGENIS Armadillo is a light-weight DataSHIELD server using a file store and an RServe server.
Likelihood-based inference for skewed count distributions, typically of degrees used in network modeling. "degreenet" is a part of the "statnet" suite of packages for network analysis. See Jones and Handcock <doi:10.1098/rspb.2003.2369>.
The debar sequence processing pipeline is designed for denoising high throughput sequencing data for the animal DNA barcode marker cytochrome c oxidase I (COI). The package is designed to detect and correct insertion and deletion errors within sequencer outputs. This is accomplished through comparison of input sequences against a profile hidden Markov model (PHMM) using the Viterbi algorithm (for algorithm details see Durbin et al. 1998, ISBN: 9780521629713). Inserted base pairs are removed and deleted base pairs are accounted for through the introduction of a placeholder character. Since the PHMM is a probabilistic representation of the COI barcode, corrections are not always perfect. For this reason debar censors base pairs adjacent to reported indel sites, turning them into placeholder characters (default is 7 base pairs in either direction, this feature can be disabled). Testing has shown that this censorship results in the correct sequence length being restored, and erroneous base pairs being masked the vast majority of the time (>95%).
Using these tools to simplify the research process of political science and other social sciences. The current version can create folder system for academic project in political science, calculate psychological trait scores, visualize experimental and spatial data, and set up color-blind palette, functions used in academic research of political psychology or political science in general.
DEploid (Zhu et.al. 2018 <doi:10.1093/bioinformatics/btx530>) is designed for deconvoluting mixed genomes with unknown proportions. Traditional phasing programs are limited to diploid organisms. Our method modifies Li and Stephenâ s algorithm with Markov chain Monte Carlo (MCMC) approaches, and builds a generic framework that allows haloptype searches in a multiple infection setting. This package provides R functions to support data analysis and results interpretation.
This package provides flexible examples of LLN and CLT for teaching purposes in secondary school.
Fit a Poisson regression to carcass distance data and integrate over the searched area at a wind farm to estimate the fraction of carcasses falling in the searched area and format the output for use as the dwp parameter in the GenEst or eoa package for estimating bird and bat mortality, following Dalthorp, et al. (2022) <arXiv:2201.10064>.
This package provides a R driver for Apache Drill<https://drill.apache.org>, which could connect to the Apache Drill cluster<https://drill.apache.org/docs/installing-drill-on-the-cluster> or drillbit<https://drill.apache.org/docs/embedded-mode-prerequisites> and get result(in data frame) from the SQL query and check the current configuration status. This link <https://drill.apache.org/docs> contains more information about Apache Drill.
Represents the content of a directory as an interactive collapsible tree. Offers the possibility to assign a text (e.g., a Readme.txt') to each folder (represented as a clickable node), so that when the user hovers the pointer over a node, the corresponding text is displayed as a tooltip.
Several tools for handling block-matrix diagonals and similar constructs are implemented. Block-diagonal matrices can be extracted or removed using two small functions implemented here. In addition, non-square matrices are supported. Block diagonal matrices occur when two dimensions of a data set are combined along one edge of a matrix. For example, trade-flow data in the decompr and gvc packages have each country-industry combination occur along both edges of the matrix.
In-line functions for multivariate optimization via desirability functions (Derringer and Suich, 1980, <doi:10.1080/00224065.1980.11980968>) with easy use within dplyr pipelines.
The load estimation method is based on a general factor model to solve the estimates of load and specific variance. The philosophy of the package is described in Guangbao Guo. (2022). <doi:10.1007/s00180-022-01270-z>.
Streamlines analysis of qualitative data exported from Dedoose <https://www.dedoose.com>. Supports monitoring thematic saturation, calculating code frequencies, organizing excerpts, generating dynamic codebooks, and producing code network maps within R'.