The user first provides design vectors n, a and b as well as null (p0) and alternative (p1) benchmark values for the probability of success. The key function "mv.plots.SM()" calculates mean values of exact upper and lower limits based on four different rank ordering methods. These plots form the basis of selecting a rank ordering. The function "inference()" calculates exact limits from a provided realisation and ordering choice. For more information, see "Exact confidence limits after a group sequential single arm binary trial" by Lloyd, C.J. (2020), Statistics in Medicine, Volume 38, 2389-2399, <doi:10.1002/sim.8909>.

Analyzes data from a Conconi et al. (1996) <doi:10.1055/s-2007-972887> treadmill fitness test where speed is augmented by a constant amount every set number of seconds to estimate the anaerobic (lactate) threshold speed and heart rate. It reads a TCX file, allows optional removal observations from before and after the actual test, fits a change-point linear model where the change-point is the estimate of the lactate threshold, and plots the data points and fit model. Details of administering the fitness test are provided in the package vignette. Functions work by default for Garmin Connect TCX exports but may require additional data preparation for heart rate, time, and speed data from other sources.

Process command line arguments, as part of a data analysis workflow. command makes it easier to construct a workflow consisting of lots of small, self-contained scripts, all run from a Makefile or shell script. The aim is a workflow that is modular, transparent, and reliable.

This package provides R users with direct access to genomic and clinical data from the cBioPortal web resource via user-friendly functions that wrap cBioPortal's existing API endpoints <https://www.cbioportal.org/api/swagger-ui/index.html>. Users can browse and query genomic data on mutations, copy number alterations and fusions, as well as data on tumor mutational burden ('TMB'), microsatellite instability status ('MSI'), FACETS and select clinical data points (depending on the study). See <https://www.cbioportal.org/> and Gao et al., (2013) <doi:10.1126/scisignal.2004088> for more information on the cBioPortal web resource.

The caroline R library contains dozens of functions useful for: database migration (dbWriteTable2), database style joins & aggregation (nerge, groupBy, & bestBy), data structure conversion (nv, tab2df), legend table making (sstable & leghead), automatic legend positioning for scatter and box plots (), plot annotation (labsegs & mvlabs), data visualization (pies, sparge, confound.grid & raPlot), character string manipulation (m & pad), file I/O (write.delim), batch scripting, data exploration, and more. The package's greatest contributions lie in the database style merge, aggregation and interface functions as well as in it's extensive use and propagation of row, column and vector names in most functions.

This package provides a comprehensive framework for time series omics analysis, integrating changepoint detection, smooth and shape-constrained trends, and uncertainty quantification. It supports gene- and transcript-level inferences, p-value aggregation for improved power, and both case-only and case-control designs. It includes an interactive shiny interface. The methods are described in Yates et al. (2024) <doi:10.1101/2024.12.22.630003>.

Calculation of consensus values for atomic weights, isotope amount ratios, and isotopic abundances with the associated uncertainties using multivariate meta-regression approach for consensus building.

Encode and decode c-squares, from and to simple feature (sf) or spatiotemporal arrays (stars) objects. Use c-squares codes to quickly join or query spatial data.

An investigative tool designed to help users visualize correlations between variables in their datasets. This package aims to provide an easy and effective way to explore and visualize these correlations, making it easier to interpret and communicate results.

Multidimensional scaling (MDS) methods that aim at pronouncing the clustered appearance of the configuration (Rusch, Mair & Hornik, 2021, <doi:10.1080/10618600.2020.1869027>). They achieve this by transforming proximities/distances with explicit power functions and penalizing the fitting criterion with a clusteredness index, the OPTICS Cordillera (Rusch, Hornik & Mair, 2018, <doi:10.1080/10618600.2017.1349664>). There are two variants: One for finding the configuration directly (COPS-C) with given explicit power transformations and implicit ratio, interval and non-metric optimal scaling transformations (Borg & Groenen, 2005, ISBN:978-0-387-28981-6), and one for using the augmented fitting criterion to find optimal hyperparameters for the explicit transformations (P-COPS). The package contains various functions, wrappers, methods and classes for fitting, plotting and displaying a large number of different MDS models (most of the functionality in smacofx) in the COPS framework. The package further contains a function for pattern search optimization, the ``Adaptive Luus-Jaakola Algorithm (Rusch, Mair & Hornik, 2021,<doi:10.1080/10618600.2020.1869027>) and a functions to calculate the phi-distances for count data or histograms.

This package provides functions to perform statistical inference of data organized in contingency tables. This package is a companion to the "Statistical Analysis of Contingency Tables" book by Fagerland et al. <ISBN 9781466588172>.

Provide functions for reading and writing CSVW - i.e. CSV tables and JSON metadata. The metadata helps interpret CSV by setting the types and variable names.

This package provides a simple countdown timer for slides and HTML documents written in R Markdown or Quarto'. Integrates fully into Shiny apps. Countdown to something amazing.

This package provides functions for fitting univariate linear regression models under Scale Mixtures of Skew-Normal (SMSN) distributions, considering left, right or interval censoring and missing responses. Estimation is performed via an EM-type algorithm. Includes selection criteria, sample generation and envelope. For details, see Gil, Y.A., Garay, A.M., and Lachos, V.H. (2025) <doi:10.1007/s10260-025-00797-x>.

This package provides a new method for interpretable heterogeneous treatment effects characterization in terms of decision rules via an extensive exploration of heterogeneity patterns by an ensemble-of-trees approach, enforcing high stability in the discovery. It relies on a two-stage pseudo-outcome regression, and it is supported by theoretical convergence guarantees. Bargagli-Stoffi, F. J., Cadei, R., Lee, K., & Dominici, F. (2023) Causal rule ensemble: Interpretable Discovery and Inference of Heterogeneous Treatment Effects. arXiv preprint <doi:10.48550/arXiv.2009.09036>.

This package implements weighted estimation in Cox regression as proposed by Schemper, Wakounig and Heinze (Statistics in Medicine, 2009, <doi:10.1002/sim.3623>) and as described in Dunkler, Ploner, Schemper and Heinze (Journal of Statistical Software, 2018, <doi:10.18637/jss.v084.i02>). Weighted Cox regression provides unbiased average hazard ratio estimates also in case of non-proportional hazards. Approximated generalized concordance probability an effect size measure for clear-cut decisions can be obtained. The package provides options to estimate time-dependent effects conveniently by including interactions of covariates with arbitrary functions of time, with or without making use of the weighting option.

Iterate and repel visually similar colors away in various ggplot2 plots. When many groups are plotted at the same time on multiple axes, for instance stacked bars or scatter plots, effectively ordering colors becomes difficult. This tool iterates through color combinations to find the best solution to maximize visual distinctness of nearby groups, so plots are more friendly toward colorblind users. This is achieved by two distance measurements, distance between groups within the plot, and CIELAB color space distances between colors as described in Carter et al., (2018) <doi:10.25039/TR.015.2018>.

Ceteris Paribus Profiles (What-If Plots) are designed to present model responses around selected points in a feature space. For example around a single prediction for an interesting observation. Plots are designed to work in a model-agnostic fashion, they are working for any predictive Machine Learning model and allow for model comparisons. Ceteris Paribus Plots supplement the Break Down Plots from breakDown package.

This package provides measures of effect sizes for summarized continuous variables as well as diagnostic accuracy statistics for 2x2 table data. Includes functions for Cohen's d, robust effect size, Cohen's q, partial eta-squared, coefficient of variation, odds ratio, likelihood ratios, sensitivity, specificity, positive and negative predictive values, Youden index, number needed to treat, number needed to diagnose, and predictive summary index.

Render tables in text format in the terminal using ANSI strings thanks to the cli and crayon packages.

Detect and quantify community assembly processes using trait values of individuals or populations, the T-statistics and other metrics, and dedicated null models. Provides tools to analyse intraspecific trait variability and its consequences for community assembly. Implements a framework using individual-level trait data to decompose variance at the population, species, and community levels. Methods are described in Taudiere and Violle (2016) <doi:10.1111/ecog.01433>.

When causal quantities are not identifiable from the observed data, it still may be possible to bound these quantities using the observed data. We outline a class of problems for which the derivation of tight bounds is always a linear programming problem and can therefore, at least theoretically, be solved using a symbolic linear optimizer. We extend and generalize the approach of Balke and Pearl (1994) <doi:10.1016/B978-1-55860-332-5.50011-0> and we provide a user friendly graphical interface for setting up such problems via directed acyclic graphs (DAG), which only allow for problems within this class to be depicted. The user can then define linear constraints to further refine their assumptions to meet their specific problem, and then specify a causal query using a text interface. The program converts this user defined DAG, query, and constraints, and returns tight bounds. The bounds can be converted to R functions to evaluate them for specific datasets, and to latex code for publication. The methods and proofs of tightness and validity of the bounds are described in a paper by Sachs, Jonzon, Gabriel, and Sjölander (2022) <doi:10.1080/10618600.2022.2071905>.

This package provides a convenient interface for making requests directly to the Civis Platform API <https://www.civisanalytics.com/platform>. Full documentation available here <https://civisanalytics.github.io/civis-r/>.

Modeling under- and over-dispersed count data using extended Poisson process models as in the article Faddy and Smith (2011) <doi:10.18637/jss.v069.i06> .