This package facilitates the analysis of single-cell RNA-seq UMI matrices. It does this by computing partitions of a cell similarity graph into small homogeneous groups of cells, which are defined as metacells (MCs). The derived MCs are then used for building different representations of the data, allowing matrix or 2D graph visualization forming a basis for analysis of cell types, subtypes, transcriptional gradients,cell-cycle variation, gene modules and their regulatory models and more.
R-based access to a large set of data variables relevant to forest ecology in British Columbia (BC), Canada. Layers are in raster format at 100m resolution in the BC Albers projection, hosted at the Federated Research Data Repository (FRDR) with <doi:10.20383/101.0283>. The collection includes: elevation; biogeoclimatic zone; wildfire; cutblocks; forest attributes from Hansen et al. (2013) <doi:10.1139/cjfr-2013-0401> and Beaudoin et al. (2017) <doi:10.1139/cjfr-2017-0184>; and rasterized Forest Insect and Disease Survey (FIDS) maps for a number of insect pest species, all covering the period 2001-2018. Users supply a polygon or point location in the province of BC, and rasterbc will download the overlapping raster tiles hosted at FRDR, merging them as needed and returning the result in R as a SpatRaster object. Metadata associated with these layers, and code for downloading them from their original sources can be found in the github repository <https://github.com/deankoch/rasterbc_src>.
RNA-sense tool compares RNA-seq time curves in two experimental conditions, i.e. wild-type and mutant, and works in three steps. At Step 1, it builds expression profile for each transcript in one condition (i.e. wild-type) and tests if the transcript abundance grows or decays significantly. Dynamic transcripts are then sorted to non-overlapping groups (time profiles) by the time point of switch up or down. At Step 2, RNA-sense outputs the groups of differentially expressed transcripts, which are up- or downregulated in the mutant compared to the wild-type at each time point. At Step 3, Correlations (Fisher's exact test) between the outputs of Step 1 (switch up- and switch down- time profile groups) and the outputs of Step2 (differentially expressed transcript groups) are calculated. The results of the correlation analysis are printed as two-dimensional color plot, with time profiles and differential expression groups at y- and x-axis, respectively, and facilitates the biological interpretation of the data.
PCA done by eigenvalue decomposition of a data correlation matrix, here it automatically determines the number of factors by eigenvalue greater than 1 and it gives the uncorrelated variables based on the rotated component scores, Such that in each principal component variable which has the high variance are selected. It will be useful for non-statisticians in selection of variables. For more information, see the <http://www.ijcem.org/papers032013/ijcem_032013_06.pdf> web page.
Color palettes for all people, including those with color vision deficiency. Popular color palette series have been organized by type and have been scored on several properties such as color-blind-friendliness and fairness (i.e. do colors stand out equally?). Own palettes can also be loaded and analysed. Besides the common palette types (categorical, sequential, and diverging) it also includes cyclic and bivariate color palettes. Furthermore, a color for missing values is assigned to each palette.
Use spectrophotometry measurements performed on insects as a way to infer pathogens virulence. Insect movements cause fluctuations in fluorescence signal, and functions are provided to estimate when the insect has died as the moment when variance in autofluorescence signal drops to zero. The package provides functions to obtain this estimate together with functions to import spectrophotometry data from a Biotek microplate reader. Details of the method are given in Parthuisot et al. (2018) <doi:10.1101/297929>.
This package provides functions to have visualization and clean-up of enriched gene ontologies (GO) terms, protein complexes and pathways (obtained from multiple databases) using ConsensusPathDB from gene set over-expression analysis. Performs clustering of pathway based on similarity of over-expressed gene sets and visualizations similar to Ingenuity Pathway Analysis (IPA) when up and down regulated genes are known. The methods are described in a paper currently submitted by Orecchioni et al, 2020 in Nanoscale.
Implementation of a parametric joint model for modelling recurrent and competing event processes using generalised survival models as described in Entrop et al., (2005) <doi:10.1002/bimj.70038>. The joint model can subsequently be used to predict the mean number of events in the presence of competing risks at different time points. Comparisons of the mean number of event functions, e.g. the differences in mean number of events between two exposure groups, are also available.
Measures different aspects of page content, structure and performance for SEO (Search Engine Optimization). Aspects covered include HTML tags used in SEO, duplicate and near-duplicate content, structured data, on-site linking structure and popularity transfer, and many other amazing things. This package can be used to generate a real, full SEO audit report, which serves to detect errors or inefficiencies on a page that can be corrected in order to optimise its performance on search engines.
Build your own universe of packages similar to the tidyverse package <https://tidyverse.org/> with this meta-package creator. Create a package-verse, or meta package, by supplying a custom name for the collection of packages and the vector of desired package names to includeâ and optionally supply a destination directory, an indicator of whether to keep the created package directory, and/or a vector of verbs implement via the usethis <http://usethis.r-lib.org/> package.
This package provides a lightweight yet powerful framework for building robust data analysis pipelines. With pipeflow', you initialize a pipeline with your dataset and construct workflows step by step by adding R functions. You can modify, remove, or insert steps and parameters at any stage, while pipeflow ensures the pipeline's integrity. Overall, this package offers a beginner-friendly framework that simplifies and streamlines the development of data analysis pipelines by making them modular, intuitive, and adaptable.
Efficient implementation of sparse group lasso with optional bound constraints on the coefficients; see <doi:10.18637/jss.v110.i06>. It supports the use of a sparse design matrix as well as returning coefficient estimates in a sparse matrix. Furthermore, it correctly calculates the degrees of freedom to allow for information criteria rather than cross-validation with very large data. Finally, the interface to compiled code avoids unnecessary copies and allows for the use of long integers.
Easy-to-use interface to X-13-ARIMA-SEATS, the seasonal adjustment software by the US Census Bureau. It offers full access to almost all options and outputs of X-13, including X-11 and SEATS, automatic ARIMA model search, outlier detection and support for user defined holiday variables, such as Chinese New Year or Indian Diwali. A graphical user interface can be used through the seasonalview package. Uses the X-13-binaries from the x13binary package.
This package provides a set of convenient functions for calculating sun-related information, including the sun's position (elevation and azimuth), and the times of sunrise, sunset, solar noon, and twilight for any given geographical location on Earth. These calculations are based on equations provided by the National Oceanic & Atmospheric Administration (NOAA) as described in "Astronomical Algorithms" by Jean Meeus (1991). A resource for researchers and professionals working in fields such as climatology, biology, and renewable energy.
A slightly modified version of rivertile layout generator for river.
Compared to rivertile, rivercarro adds:
Monocle layout, views will takes all the usable area on the screen.
Gaps instead of padding around views or layout area.
Modify gaps size at runtime.
Smart gaps, if there is only one view, gaps will be disable.
Limit the width of the usable area of the screen.
Per tag configurations.
Cycle through layout
Analysis of network community objects with applications to neuroimaging data. There are two main components to this package. The first is the hierarchical multimodal spinglass (HMS) algorithm, which is a novel community detection algorithm specifically tailored to the unique issues within brain connectivity. The other is a suite of semiparametric kernel machine methods that allow for statistical inference to be performed to test for potential associations between these community structures and an outcome of interest (binary or continuous).
This package creates a 3D data cube view of a RasterStack/Brick, typically a collection/array of RasterLayers (along z-axis) with the same geographical extent (x and y dimensions) and resolution, provided by package raster'. Slices through each dimension (x/y/z), freely adjustable in location, are mapped to the visible sides of the cube. The cube can be freely rotated. Zooming and panning can be used to focus on different areas of the cube.
Explore calcium (Ca) and phosphate (Pi) homeostasis with two novel Shiny apps, building upon on a previously published mathematical model written in C, to ensure efficient computations. The underlying model is accessible here <https://pubmed.ncbi.nlm.nih.gov/28747359/)>. The first application explores the fundamentals of Ca-Pi homeostasis, while the second provides interactive case studies for in-depth exploration of the topic, thereby seeking to foster student engagement and an integrative understanding of Ca-Pi regulation.
Makes it easy to engage with the Application Program Interface (API) of the TCdata360 and Govdata360 platforms at <https://tcdata360.worldbank.org/> and <https://govdata360.worldbank.org/>, respectively. These application program interfaces provide access to over 5000 trade, competitiveness, and governance indicator data, metadata, and related information from sources both inside and outside the World Bank Group. Package functions include easier download of data sets, metadata, and related information, as well as searching based on user-inputted query.
An implementation of major general-purpose mechanisms for privatizing statistics, models, and machine learners, within the framework of differential privacy of Dwork et al. (2006) <doi:10.1007/11681878_14>. Example mechanisms include the Laplace mechanism for releasing numeric aggregates, and the exponential mechanism for releasing set elements. A sensitivity sampler (Rubinstein & Alda, 2017) <arXiv:1706.02562> permits sampling target non-private function sensitivity; combined with the generic mechanisms, it permits turn-key privatization of arbitrary programs.
This package provides several functions to create and manipulate fuzzy cognitive maps. It is based on FCMapper for Excel, distributed at <http:// www.fcmappers.net/joomla/>, developed by Michael Bachhofer and Martin Wildenberg. Maps are inputted as adjacency matrices. Attributes of the maps and the equilibrium values of the concepts (including with user-defined constrained values) can be calculated. The maps can be graphed with a function that calls igraph'. Multiple maps with shared concepts can be aggregated.
This package provides a quantile-quantile plot can be used to compare a sample of p-values to the uniform distribution. But when the dataset is big (i.e. > 1e4 p-values), plotting the quantile-quantile plot can be slow. geom_QQ uses all the data to calculate the quantiles, but thins it out in a way that focuses on points near zero before plotting to speed up plotting and decrease file size, when vector graphics are stored.
This package provides methods to test whether time series is consistent with white noise. Two new tests based on Haar wavelets and general wavelets described by Nason and Savchev (2014) <doi:10.1002/sta4.69> are provided and, for comparison purposes this package also implements the B test of Bartlett (1967) <doi:10.2307/2333850>. Functionality is provided to compute an approximation to the theoretical power of the general wavelet test in the case of general ARMA alternatives.
Carry out comparative authorship analysis of disputed and undisputed texts within the Likelihood Ratio Framework for expressing evidence in forensic science. This package contains implementations of well-known algorithms for comparative authorship analysis, such as Smith and Aldridge's (2011) Cosine Delta <doi:10.1080/09296174.2011.533591> or Koppel and Winter's (2014) Impostors Method <doi:10.1002/asi.22954>, as well as functions to measure their performance and to calibrate their outputs into Log-Likelihood Ratios.