Helps you determine the analysis window to use when analyzing densely-sampled time-series data, such as EEG data, using permutation testing (Maris & Oostenveld, 2007) <doi:10.1016/j.jneumeth.2007.03.024>. These permutation tests can help identify the timepoints where significance of an effect begins and ends, and the results can be plotted in various types of heatmap for reporting. Mixed-effects models are supported using an implementation of the approach by Lee & Braun (2012) <doi:10.1111/j.1541-0420.2011.01675.x>.

The permubiome R package was created to perform a permutation-based non-parametric analysis on microbiome data for biomarker discovery aims. This test executes thousands of comparisons in a pairwise manner, after a random shuffling of data into the different groups of study with a prior selection of the microbiome features with the largest variation among groups. Previous to the permutation test itself, data can be normalized according to different methods proposed to handle microbiome data ('proportions or Anders'). The median-based differences between groups resulting from the multiple simulations are fitted to a normal distribution with the aim to calculate their significance. A multiple testing correction based on Benjamini-Hochberg method (fdr) is finally applied to extract the differentially presented features between groups of your dataset. LATEST UPDATES: v1.1 and olders incorporates function to parse COLUMN format; v1.2 and olders incorporates -optimize- function to maximize evaluation of features with largest inter-class variation; v1.3 and olders includes the -size.effect- function to perform estimation statistics using the bootstrap-coupled approach implemented in the dabestr (>=0.3.0) R package. Current v1.3.2 fixed bug with "Class" recognition and updated dabestr functions.

Currently incorporate the generalized odds-rate model (a type of linear transformation model) for interval-censored data based on penalized monotonic B-Spline. More methods under other semiparametric models such as cure model or additive model will be included in future versions. For more details see Lu, M., Liu, Y., Li, C. and Sun, J. (2019) <arXiv:1912.11703>.

This package contains the functions for construction and visualization of various families of the proximity catch digraphs (PCDs), see (Ceyhan (2005) ISBN:978-3-639-19063-2), for computing the graph invariants for testing the patterns of segregation and association against complete spatial randomness (CSR) or uniformity in one, two and three dimensional cases. The package also has tools for generating points from these spatial patterns. The graph invariants used in testing spatial point data are the domination number (Ceyhan (2011) <doi:10.1080/03610921003597211>) and arc density (Ceyhan et al. (2006) <doi:10.1016/j.csda.2005.03.002>; Ceyhan et al. (2007) <doi:10.1002/cjs.5550350106>). The PCD families considered are Arc-Slice PCDs, Proportional-Edge PCDs, and Central Similarity PCDs.

This package provides a toolbox for writing knitr', Sweave or other LaTeX'- or markdown'-based reports and to prettify the output of various estimated models.

The main attribute of PopVar is the prediction of genetic variance in bi-parental populations, from which the package derives its name. PopVar contains a set of functions that use phenotypic and genotypic data from a set of candidate parents to 1) predict the mean, genetic variance, and superior progeny value of all, or a defined set of pairwise bi-parental crosses, and 2) perform cross-validation to estimate genome-wide prediction accuracy of multiple statistical models. More details are available in Mohammadi, Tiede, and Smith (2015, <doi:10.2135/cropsci2015.01.0030>). A dataset think_barley.rda is included for reference and examples.

This package provides a collection of tools to handle microsatellite data of any ploidy (and samples of mixed ploidy) where allele copy number is not known in partially heterozygous genotypes. It can import and export data in ABI GeneMapper', Structure', ATetra', Tetrasat'/'Tetra', GenoDive', SPAGeDi', POPDIST', STRand', and binary presence/absence formats. It can calculate pairwise distances between individuals using a stepwise mutation model or infinite alleles model, with or without taking ploidies and allele frequencies into account. These distances can be used for the calculation of clonal diversity statistics or used for further analysis in R. Allelic diversity statistics and Polymorphic Information Content are also available. polysat can assist the user in estimating the ploidy of samples, and it can estimate allele frequencies in populations, calculate pairwise or global differentiation statistics based on those frequencies, and export allele frequencies to SPAGeDi and adegenet'. Functions are also included for assigning alleles to isoloci in cases where one pair of microsatellite primers amplifies alleles from two or more independently segregating isoloci. polysat is described by Clark and Jasieniuk (2011) <doi:10.1111/j.1755-0998.2011.02985.x> and Clark and Schreier (2017) <doi:10.1111/1755-0998.12639>.

The PP package includes estimation of (MLE, WLE, MAP, EAP, ROBUST) person parameters for the 1,2,3,4-PL model and the GPCM (generalized partial credit model). The parameters are estimated under the assumption that the item parameters are known and fixed. The package is useful e.g. in the case that items from an item pool / item bank with known item parameters are administered to a new population of test-takers and an ability estimation for every test-taker is needed.

Derives prediction rule ensembles (PREs). Largely follows the procedure for deriving PREs as described in Friedman & Popescu (2008; <DOI:10.1214/07-AOAS148>), with adjustments and improvements described in Fokkema (2020; <DOI:10.18637/jss.v092.i12>) and Fokkema & Strobl (2020; <DOI:10.1037/met0000256>). The main function pre() derives prediction rule ensembles consisting of rules and/or linear terms for continuous, binary, count, multinomial, survival and multivariate continuous responses. Function gpe() derives generalized prediction ensembles, consisting of rules, hinge and linear functions of the predictor variables.

This package provides methods to calculate and present PHENTHAUproc', an early warning and decision support system for hazard assessment and control of oak processionary moth (OPM) using local and spatial temperature data. It was created by Halbig et al. 2024 (<doi:10.1016/j.foreco.2023.121525>) at FVA (<https://www.fva-bw.de/en/homepage/>) Forest Research Institute Baden-Wuerttemberg, Germany and at BOKU - University of Natural Ressources and Life Sciences, Vienna, Austria.

This package provides a coding assistant using Perplexity's Large Language Models <https://www.perplexity.ai/> API. A set of functions and RStudio add-ins that aim to help R developers.

Build and manipulate partially ordered sets (posets), to perform some data analysis on them and to implement multi-criteria decision making procedures. Several efficient ways for generating linear extensions are implemented, together with functions for building mutual ranking probabilities, incomparability, dominance and separation scores (Fattore, M., De Capitani, L., Avellone, A., Suardi, A. (2024). A fuzzy posetic toolbox for multi-criteria evaluation on ordinal data systems. ANNALS OF OPERATIONS RESEARCH <doi:10.1007/s10479-024-06352-3>).

This package provides a RStudio addin allowing to paste the content of the clipboard as a comment block or as roxygen lines. This is very useful to insert an example in the roxygen block.

This tool computes the probability of detection (POD) curve and the limit of detection (LOD), i.e. the number of copies of the target DNA sequence required to ensure a 95 % probability of detection (LOD95). Other quantiles of the LOD can be specified. This is a reimplementation of the mathematical-statistical modelling of the validation of qualitative polymerase chain reaction (PCR) methods within a single laboratory as provided by the commercial tool PROLab <http://quodata.de/>. The modelling itself has been described by Uhlig et al. (2015) <doi:10.1007/s00769-015-1112-9>.

This package provides a probabilistic framework that integrates Data Envelopment Analysis (DEA) (Banker et al., 1984) <doi:10.1287/mnsc.30.9.1078> with machine learning classifiers (Kuhn, 2008) <doi:10.18637/jss.v028.i05> to estimate both the (in)efficiency status and the probability of efficiency for decision-making units. The approach trains predictive models on DEA-derived efficiency labels (Charnes et al., 1985) <doi:10.1016/0304-4076(85)90133-2>, enabling explainable artificial intelligence (XAI) workflows with global and local interpretability tools, including permutation importance (Molnar et al., 2018) <doi:10.21105/joss.00786>, Shapley value explanations (Strumbelj & Kononenko, 2014) <doi:10.1007/s10115-013-0679-x>, and sensitivity analysis (Cortez, 2011) <https://CRAN.R-project.org/package=rminer>. The framework also supports probability-threshold peer selection and counterfactual improvement recommendations for benchmarking and policy evaluation. The probabilistic efficiency framework is detailed in González-Moyano et al. (2025) "Probability-based Technical Efficiency Analysis through Machine Learning", in review for publication.

This package provides a system for fast, accurate, and flexible whole genome bisulfite sequencing (WGBS) data analysis of two-condition comparisons. Principal Component BiSulfite, PCBS', assigns methylated loci eigenvector values from the treatment-delineating principal component in lieu of running millions of pairwise statistical tests, which dramatically increases analysis flexibility and reduces computational requirements. Methods: <https://katlande.github.io/PCBS/articles/Differential_Methylation.html>.

Statistical functions to describe a Pareto Positive Stable (PPS) distribution and fit it to real data. Graphical and statistical tools to validate the fits are included.

Simplifies the manufacturing, analysis and display of pressure volume and leaf drying curves. From the progression of the curves turgor loss point, osmotic potential, apoplastic fraction as well as minimum conductance and stomatal closure can be derived. Methods adapted from Bartlett, Scoffoni, Sack (2012) <doi:10.1111/j.1461-0248.2012.01751.x> and Sack, Scoffoni, PrometheusWikiContributors (2011) <http://prometheuswiki.org/tiki-index.php?page=Minimum+epidermal+conductance+%28gmin%2C+a.k.a.+cuticular+conductance%29>.

This package provides access to material from the book "Processing and Analyzing Financial Data with R" by Marcelo Perlin (2017) available at <https://sites.google.com/view/pafdr/home>.

Estimates power, minimum detectable effect size (MDES) and sample size requirements. The context is multilevel randomized experiments with multiple outcomes. The estimation takes into account the use of multiple testing procedures. Development of this package was supported by a grant from the Institute of Education Sciences (R305D170030). For a full package description, including a detailed technical appendix, see <doi:10.18637/jss.v108.i06>.

Parsimonious Ultrametric Gaussian Mixture Models via grouped coordinate ascent (equivalent to EM) algorithm characterized by the inspection of hierarchical relationships among variables via parsimonious extended ultrametric covariance structures. The methodologies are described in Cavicchia, Vichi, Zaccaria (2024) <doi:10.1007/s11222-024-10405-9>, (2022) <doi:10.1007/s11634-021-00488-x> and (2020) <doi:10.1007/s11634-020-00400-z>.

Extracts features from amplification curve data of quantitative Polymerase Chain Reactions (qPCR) according to Pabinger et al. 2014 <doi:10.1016/j.bdq.2014.08.002> for machine learning purposes. Helper functions prepare the amplification curve data for processing as functional data (e.g., Hausdorff distance) or enable the plotting of amplification curve classes (negative, ambiguous, positive). The hookreg() and hookregNL() functions of Burdukiewicz et al. (2018) <doi:10.1016/j.bdq.2018.08.001> can be used to predict amplification curves with an hook effect-like curvature. The pcrfit_single() function can be used to extract features from an amplification curve.

This package provides various functions for retrieving and interpreting information from Pubmed via the API, <https://www.ncbi.nlm.nih.gov/home/develop/api/>.

This package provides a collection of easy-to-use tools for regression analysis of survival data with a cure fraction proposed in Su et al. (2022) <doi:10.1177/09622802221108579>. The modeling framework is based on the Cox proportional hazards mixture cure model and the bounded cumulative hazard (promotion time cure) model. The pseudo-observations approach is utilized to assess covariate effects and embedded in the variable selection procedure.