Convert BCD (raw bytes) to decimal numbers and vice versa. BCD format is used to preserve decimals exactly, as opposed to the binary rounding errors inherent in "numeric" or "floating-point" formats.

This package contains the Multi-Species Acute Toxicity Database (CAS & SMILES columns only) [United States (US) Department of Health and Human Services (DHHS) National Institutes of Health (NIH) National Cancer Institute (NCI), "Multi-Species Acute Toxicity Database", <https://cactus.nci.nih.gov/download/acute-toxicity-db/>] combined with the Toxic Substances Control Act (TSCA) Inventory [United States Environmental Protection Agency (US EPA), "Toxic Substances Control Act (TSCA) Chemical Substance Inventory", <https://www.epa.gov/tsca-inventory/how-access-tsca-inventory

This package provides a wrapper for circlize'. All components are based on classes and objects. Users can use the addition symbol (+) to combine components for a circular visualization with ggplot2 style.The package is described in Zhang Z, Cao T, Huang Y and Xia Y (2025) <doi:10.3389/fgene.2025.1535368>.

This package provides functions for performing experimental comparisons of algorithms using adequate sample sizes for power and accuracy. Implements the methodology originally presented in Campelo and Takahashi (2019) <doi:10.1007/s10732-018-9396-7> for the comparison of two algorithms, and later generalised in Campelo and Wanner (Submitted, 2019) <arxiv:1908.01720>.

Simple functions for plotting linear calibration functions and estimating standard errors for measurements according to the Handbook of Chemometrics and Qualimetrics: Part A by Massart et al. (1997) There are also functions estimating the limit of detection (LOD) and limit of quantification (LOQ). The functions work on model objects from - optionally weighted - linear regression (lm) or robust linear regression ('rlm from the MASS package).

The level-dependent cross-validation method is implemented for the selection of thresholding value in wavelet shrinkage. This procedure is implemented by coupling a conventional cross validation with an imputation method due to a limitation of data length, a power of 2. It can be easily applied to classical leave-one-out and k-fold cross validation. Since the procedure is computationally fast, a level-dependent cross validation can be performed for wavelet shrinkage of various data such as a data with correlated errors.

Covariance is of universal prevalence across various disciplines within statistics. We provide a rich collection of geometric and inferential tools for convenient analysis of covariance structures, topics including distance measures, mean covariance estimator, covariance hypothesis test for one-sample and two-sample cases, and covariance estimation. For an introduction to covariance in multivariate statistical analysis, see Schervish (1987) <doi:10.1214/ss/1177013111>.

Uses a calibrated model fusion approach to optimally combine multiple surrogate markers. Specifically, two initial estimates of optimal composite scores of the markers are obtained; the optimal calibrated combination of the two estimated scores is then constructed which ensures both validity of the final combined score and optimality with respect to the proportion of treatment effect explained (PTE) by the final combined score. The primary function, pte.estimate.multiple(), estimates the PTE of the identified combination of multiple surrogate markers. Details are described in Wang et al (2022) <doi:10.1111/biom.13677>. A tutorial for the package is available at <https://www.laylaparast.com/cmfsurrogate> and a Shiny App is available at <https://parastlab.shinyapps.io/CMFsurrogateApp/>.

Perform additional multiple testing procedure methods to p.adjust(), such as weighted Hochberg (Tamhane, A. C., & Liu, L., 2008) <doi:10.1093/biomet/asn018>, ICC adjusted Bonferroni method (Shi, Q., Pavey, E. S., & Carter, R. E., 2012) <doi:10.1002/pst.1514> and a new correlation corrected weighted Hochberg for correlated endpoints.

This package provides a method for determining groups in multiple curves with an automatic selection of their number based on k-means or k-medians algorithms. The selection of the optimal number is provided by bootstrap methods or other approaches with lower computational cost. The methodology can be applied both in regression and survival framework. Implemented methods are: Grouping multiple survival curves described by Villanueva et al. (2018) <doi:10.1002/sim.8016>.

This package provides methods for estimating circular graphical models using maximum likelihood estimation (MLE) and circular mean squared error (CMSE) approaches. The package includes tools for model fitting, network construction, network evaluation, and visualization. The CMSE-based methodology is related to Dar (2023) <https://open.metu.edu.tr/handle/11511/102577>. The package supports both simulated circular data and real-world applications, including gene-expression network analysis.

Fits a pseudo Cox proprotional hazards model when survival times are missing for control groups.

Given response y, continuous predictor x, and covariate matrix, the relationship between E(y) and x is estimated with a shape constrained regression spline. Function outputs fits and various types of inference.

Allows users to seamlessly query several CDC PLACES APIs (<https://data.cdc.gov/browse?q=PLACES%20&sortBy=relevance>) by geography, state, measure, and release year. This package also contains a function to explore the available measures for each release year.

Download and analyse international merchandise and services trade data from the United Nations Comtrade database <https://comtradeplus.un.org/>. Retrieve bilateral trade flows, compute trade analytics (revealed comparative advantage, trade concentration, trade balance), and convert between commodity classifications (Harmonised System HS', Standard International Trade Classification SITC', Broad Economic Categories BEC'). Covers 200+ reporter countries, 60+ years of goods trade data (1962-present), and services trade via Extended Balance of Payments Services ('EBOPS'). Works without registration for basic queries. A free Application Programming Interface ('API') key from <https://comtradedeveloper.un.org/> unlocks full access.

Calculates the credit debt for the next period based on the available data using the cross-classification credibility model.

An interactive shiny training companion for people who are new to data, developed for World Health Organization data trainings. Bundles hands-on modules for importing data, missing values, outliers, text cleaning, merging, visualization, and basic statistics, plus a set of AI-skills pages (prompting levels, a prompt gallery, AI safety rules, and a methodology case study) and an interactive quiz with per-session topic filters. Launch the app with run_cata().

This package provides a user friendly function crrcbcv to compute bias-corrected variances for competing risks regression models using proportional subdistribution hazards with small-sample clustered data. Four types of bias correction are included: the MD-type bias correction by Mancl and DeRouen (2001) <doi:10.1111/j.0006-341X.2001.00126.x>, the KC-type bias correction by Kauermann and Carroll (2001) <doi:10.1198/016214501753382309>, the FG-type bias correction by Fay and Graubard (2001) <doi:10.1111/j.0006-341X.2001.01198.x>, and the MBN-type bias correction by Morel, Bokossa, and Neerchal (2003) <doi:10.1002/bimj.200390021>.

This package provides a framework that facilitates spatio-temporal analysis of climate dynamics through exploring and measuring different dimensions of climate change in space and time.

Simulation of the stochastic 3D structure model for the nanoporous binder-conductive additive phase in battery cathodes introduced in P. Gräfensteiner, M. Osenberg, A. Hilger, N. Bohn, J. R. Binder, I. Manke, V. Schmidt, M. Neumann (2024) <doi:10.48550/arXiv.2409.11080>. The model is developed for a binder-conductive additive phase of consisting of carbon black, polyvinylidene difluoride binder and graphite particles. For its stochastic 3D modeling, a three-step procedure based on methods from stochastic geometry is used. First, the graphite particles are described by a Boolean model with ellipsoidal grains. Second, the mixture of carbon black and binder is modeled by an excursion set of a Gaussian random field in the complement of the graphite particles. Third, large pore regions within the mixture of carbon black and binder are described by a Boolean model with spherical grains.

Use machine learning algorithms and advanced geographic information system tools to build Species Distribution Modeling in a extensible and modern fashion.

This package provides a set of functions to manage CRAN'-like repositories efficiently.

Generate a candidate code list for the Observational Medical Outcomes Partnership (OMOP) common data model based on string matching. For a given search strategy, a candidate code list will be returned.

Applies the change-in-effect estimate method to assess confounding effects in medical and epidemiological research (Greenland & Pearce (2016) <doi:10.1146/annurev-publhealth-031914-122559> ). It starts with a crude model including only the outcome and exposure variables. At each of the subsequent steps, one variable which creates the largest change among the remaining variables is selected. This process is repeated until all variables have been entered into the model (Wang Z. Stata Journal 2007; 7, Number 2, pp. 183â 196). Currently, the chest package has functions for linear regression, logistic regression, negative binomial regression, Cox proportional hazards model and conditional logistic regression.