Assess the agreement in method comparison studies by tolerance intervals and errors-in-variables (EIV) regressions. The Ordinary Least Square regressions (OLSv and OLSh), the Deming Regression (DR), and the (Correlated)-Bivariate Least Square regressions (BLS and CBLS) can be used with unreplicated or replicated data. The BLS() and CBLS() are the two main functions to estimate a regression line, while XY.plot() and MD.plot() are the two main graphical functions to display, respectively an (X,Y) plot or (M,D) plot with the BLS or CBLS results. Four hyperbolic statistical intervals are provided: the Confidence Interval (CI), the Confidence Bands (CB), the Prediction Interval and the Generalized prediction Interval. Assuming no proportional bias, the (M,D) plot (Band-Altman plot) may be simplified by calculating univariate tolerance intervals (beta-expectation (type I) or beta-gamma content (type II)). Major updates from last version 1.0.0 are: title shortened, include the new functions BLS.fit() and CBLS.fit() as shortcut of the, respectively, functions BLS() and CBLS(). References: B.G. Francq, B. Govaerts (2016) <doi:10.1002/sim.6872>, B.G. Francq, B. Govaerts (2014) <doi:10.1016/j.chemolab.2014.03.006>, B.G. Francq, B. Govaerts (2014) <http://publications-sfds.fr/index.php/J-SFdS/article/view/262>, B.G. Francq (2013), PhD Thesis, UCLouvain, Errors-in-variables regressions to assess equivalence in method comparison studies, <https://dial.uclouvain.be/pr/boreal/object/boreal%3A135862/datastream/PDF_01/view>.

Bayesian purity model to estimate tumor purity using methylation array data (DNA methylation Infinium 450K array data) without reference samples.

Implementation of algorithms for cutting numerical values exhibiting a potentially highly skewed distribution into evenly distributed groups (bins). This functionality can be applied for binning discrete values, such as counts, as well as for discretization of continuous values, for example, during generation of features used in machine learning algorithms.

Assigns standardized diagnoses using the Banff Classification (Category 1 to 6 diagnoses, including Acute and Chronic active T-cell mediated rejection as well as Active, Chronic active, and Chronic antibody mediated rejection). The main function considers a minimal dataset containing biopsies information in a specific format (described by a data dictionary), verifies its content and format (based on the data dictionary), assigns diagnoses, and creates a summary report. The package is developed on the reference guide to the Banff classification of renal allograft pathology Roufosse C, Simmonds N, Clahsen-van Groningen M, et al. A (2018) <doi:10.1097/TP.0000000000002366>. The full description of the Banff classification is available at <https://banfffoundation.org/>.

Generates different posterior distributions of adjusted odds ratio under different priors of sensitivity and specificity, and plots the models for comparison. It also provides estimations for the specifications of the models using diagnostics of exposure status with a non-linear mixed effects model. It implements the methods that are first proposed in <doi:10.1016/j.annepidem.2006.04.001> and <doi:10.1177/0272989X09353452>.

Bayesian quantile regression using the asymmetric Laplace distribution, both continuous as well as binary dependent variables are supported. The package consists of implementations of the methods of Yu & Moyeed (2001) <doi:10.1016/S0167-7152(01)00124-9>, Benoit & Van den Poel (2012) <doi:10.1002/jae.1216> and Al-Hamzawi, Yu & Benoit (2012) <doi:10.1177/1471082X1101200304>. To speed up the calculations, the Markov Chain Monte Carlo core of all algorithms is programmed in Fortran and called from R.

This package provides a set of functions to allow analysis of count data (such as faecal egg count data) using Bayesian MCMC methods. Returns information on the possible values for mean count, coefficient of variation and zero inflation (true prevalence) present in the data. A complete faecal egg count reduction test (FECRT) model is implemented, which returns inference on the true efficacy of the drug from the pre- and post-treatment data provided, using non-parametric bootstrapping as well as using Bayesian MCMC. Functions to perform power analyses for faecal egg counts (including FECRT) are also provided.

This package implements optimal matching with near-fine balance in large observational studies with the use of optimal calipers to get a sparse network. The caliper is optimal in the sense that it is as small as possible such that a matching exists. The main functions in the bigmatch package are optcal() to find the optimal caliper, optconstant() to find the optimal number of nearest neighbors, and nfmatch() to find a near-fine balance match with a caliper and a restriction on the number of nearest neighbors. Yu, R., Silber, J. H., and Rosenbaum, P. R. (2020). <DOI:10.1214/19-sts699>.

Extends the BatchJobs package to run statistical experiments on batch computing clusters. For further details see the project web page.

Analyse single case analyses against a control group. Its purpose is to provide a flexible, with good power and low first type error approach that can manage at the same time controls and patient's data. The use of Bayesian statistics allows to test both the alternative and null hypothesis. Scandola, M., & Romano, D. (2020, August 3). <doi:10.31234/osf.io/sajdq> Scandola, M., & Romano, D. (2021). <doi:10.1016/j.neuropsychologia.2021.107834>.

Collection of tools to make R more convenient. Includes tools to summarize data using statistics not available with base R and manipulate objects for analyses.

The Bayesian optimal interval (BOIN) design is a novel phase I clinical trial design for finding the maximum tolerated dose (MTD). It can be used to design both single-agent and drug-combination trials. The BOIN design is motivated by the top priority and concern of clinicians when testing a new drug, which is to effectively treat patients and minimize the chance of exposing them to subtherapeutic or overly toxic doses. The prominent advantage of the BOIN design is that it achieves simplicity and superior performance at the same time. The BOIN design is algorithm-based and can be implemented in a simple way similar to the traditional 3+3 design. The BOIN design yields an average performance that is comparable to that of the continual reassessment method (CRM, one of the best model-based designs) in terms of selecting the MTD, but has a substantially lower risk of assigning patients to subtherapeutic or overly toxic doses. For tutorial, please check Yan et al. (2020) <doi:10.18637/jss.v094.i13>.

Statistical methods for analyzing binary replicates, which are noisy binary measurements of latent binary states. Provides scoring functions (average, median, likelihood-based, and Bayesian) to estimate the probability that an individual is in the positive state. Includes maximum a posteriori estimation via the EM algorithm and full Bayesian inference via Stan. Supports classification with inconclusive decisions and prevalence estimation.

An interface for the Neo4j database providing mapping between different identifiers of biological entities. This Biological Entity Dictionary (BED) has been developed to address three main challenges. The first one is related to the completeness of identifier mappings. Indeed, direct mapping information provided by the different systems are not always complete and can be enriched by mappings provided by other resources. More interestingly, direct mappings not identified by any of these resources can be indirectly inferred by using mappings to a third reference. For example, many human Ensembl gene ID are not directly mapped to any Entrez gene ID but such mappings can be inferred using respective mappings to HGNC ID. The second challenge is related to the mapping of deprecated identifiers. Indeed, entity identifiers can change from one resource release to another. The identifier history is provided by some resources, such as Ensembl or the NCBI, but it is generally not used by mapping tools. The third challenge is related to the automation of the mapping process according to the relationships between the biological entities of interest. Indeed, mapping between gene and protein ID scopes should not be done the same way than between two scopes regarding gene ID. Also, converting identifiers from different organisms should be possible using gene orthologs information. The method has been published by Godard and van Eyll (2018) <doi:10.12688/f1000research.13925.3>.

Bayes factors and posterior probabilities in Linear models, aimed at provide a formal Bayesian answer to testing and variable selection problems.

Distributes Gaussian process calculations across nodes in a distributed memory setting, using Rmpi. The bigGP class provides high-level methods for maximum likelihood with normal data, prediction, calculation of uncertainty (i.e., posterior covariance calculations), and simulation of realizations. In addition, bigGP provides an API for basic matrix calculations with distributed covariance matrices, including Cholesky decomposition, back/forwardsolve, crossproduct, and matrix multiplication.

Generalization of the Bayesian classification and regression tree (CART) model that partitions subjects into terminal nodes and tailors regression model to each terminal node.

The BAGofT assesses the goodness-of-fit of binary classifiers. Details can be found in Zhang, Ding and Yang (2021) <arXiv:1911.03063v2>.

The goal of the package is to provide an easy-to-use method for estimating degrees of relatedness (up to the second degree) for extreme low-coverage data. The package also allows users to quantify and visualise the level of confidence in the estimated degrees of relatedness.

Select balanced and spatially balanced probability samples in multi-dimensional spaces with any prescribed inclusion probabilities. It contains fast (C++ via Rcpp) implementations of the included sampling methods. The local pivotal method by Grafström, Lundström and Schelin (2012) <doi:10.1111/j.1541-0420.2011.01699.x> and spatially correlated Poisson sampling by Grafström (2012) <doi:10.1016/j.jspi.2011.07.003> are included. Also the cube method (for balanced sampling) and the local cube method (for doubly balanced sampling) are included, see Grafström and Tillé (2013) <doi:10.1002/env.2194>.

R functions to read EURING data and analyse re-encounter data of birds marked by metal rings. For a tutorial, go to <doi:10.1080/03078698.2014.933053>.

This package provides a lightweight modelling syntax for defining likelihoods and priors and for computing Bayes factors for simple one parameter models. It includes functionality for computing and plotting priors, likelihoods, and model predictions. Additional functionality is included for computing and plotting posteriors.

This package contains data sets regarding songs on the Billboard Hot 100 list from 1960 to 2016. The data sets include the ranks for the given year, musical features of a lot of the songs and lyrics for several of the songs as well.

Computes approximated adjusted fractional Bayes factors for equality, inequality, and about equality constrained hypotheses. For a tutorial on this method, see Hoijtink, Mulder, van Lissa, & Gu, (2019) <doi:10.1037/met0000201>. For applications in structural equation modeling, see: Van Lissa, Gu, Mulder, Rosseel, Van Zundert, & Hoijtink, (2021) <doi:10.1080/10705511.2020.1745644>. For the statistical underpinnings, see Gu, Mulder, and Hoijtink (2018) <doi:10.1111/bmsp.12110>; Hoijtink, Gu, & Mulder, J. (2019) <doi:10.1111/bmsp.12145>; Hoijtink, Gu, Mulder, & Rosseel, (2019) <doi:10.31234/osf.io/q6h5w>.