Compressed spatial vector data originally from <https://dawadocs.dataforsyningen.dk/> saved as Simple Features, SF, objects with data on population, age and gender from Statistics Denmark <https://www.dst.dk/da/>.

This package provides a collection of supervised discretization algorithms. It can also be grouped in terms of top-down or bottom-up, implementing the discretization algorithms.

Fast & memory-efficient functions to analyze and manipulate large spatial data data sets. It leverages the fast analytical capabilities of DuckDB and its spatial extension (see <https://duckdb.org/docs/stable/core_extensions/spatial/overview>) while maintaining compatibility with Râ s spatial data ecosystem to work with spatial vector data.

Data frame, tibble, or tbl objects are converted to data package objects using specific metadata labels (name, version, title, homepage, description). A data package object ('dpkg') can be written to disk as a parquet file or released to a GitHub repository. Data package objects can be read into R from online repositories and downloaded files are cached locally across R sessions.

Similarity of dissolution profiles is assessed using the similarity factor f2 according to the EMA guideline (European Medicines Agency 2010) "On the investigation of bioequivalence". Dissolution profiles are regarded as similar if the f2 value is between 50 and 100. For the applicability of the similarity factor f2, the variability between profiles needs to be within certain limits. Often, this constraint is violated. One possibility in this situation is to resample the measured profiles in order to obtain a bootstrap estimate of f2 (Shah et al. (1998) <doi:10.1023/A:1011976615750>). Other alternatives are the model-independent non-parametric multivariate confidence region (MCR) procedure (Tsong et al. (1996) <doi:10.1177/009286159603000427>) or the T2-test for equivalence procedure (Hoffelder (2016) <https://www.ecv.de/suse_item.php?suseId=Z|pi|8430>). Functions for estimation of f1, f2, bootstrap f2, MCR / T2-test for equivalence procedure are implemented.

S4-distribution classes based on package distr for distributions from packages fBasics and fGarch'.

This package provides tools for working with a new versatile discrete distribution, the db ("discretised Beta") distribution. This package provides density (probability), distribution, inverse distribution (quantile) and random data generation functions for the db family. It provides functions to effect conveniently maximum likelihood estimation of parameters, and a variety of useful plotting functions. It provides goodness of fit tests and functions to calculate the Fisher information, different estimates of the hessian of the log likelihood and Monte Carlo estimation of the covariance matrix of the maximum likelihood parameter estimates. In addition it provides analogous tools for working with the beta-binomial distribution which has been proposed as a competitor to the db distribution.

Provide a Dens-based method for estimating functional connection in large scale brain networks using partial correlation.

An extension to the DPQ package with computations for DPQ (Density (pdf), Probability (cdf) and Quantile) functions, where the functions here partly use the Rmpfr package and hence the underlying MPFR and GMP C libraries.

This package implements the de-biased estimator for low-rank matrix completion and provides confidence intervals for entries of interest. See: by Chen et al. (2019) <doi:10.1073/pnas.1910053116>, Mai (2021) <arXiv:2103.11749>.

This package provides functions for fitting Cox proportional hazards models for grouped time-to-event data, where the shared group-specific frailties have a discrete nonparametric distribution. The methods proposed in the package is described by Gasperoni, F., Ieva, F., Paganoni, A. M., Jackson, C. H., Sharples, L. (2018) <doi:10.1093/biostatistics/kxy071>. There are also functions for simulating from these models, with a nonparametric or a parametric baseline hazard function.

This package provides a common interface for applying dimensionality reduction methods, such as Principal Component Analysis ('PCA'), Independent Component Analysis ('ICA'), diffusion maps, Locally-Linear Embedding ('LLE'), t-distributed Stochastic Neighbor Embedding ('t-SNE'), and Uniform Manifold Approximation and Projection ('UMAP'). Has built-in support for sparse matrices.

Perform tree-ring analyses such as detrending, chronology building, and cross dating. Read and write standard file formats used in dendrochronology.

Dual Wavelet based Nonlinear Autoregressive Distributed Lag model has been developed for noisy time series analysis. This package is designed to capture both short-run and long-run relationships in time series data, while incorporating wavelet transformations. The methodology combines the NARDL model with wavelet decomposition to better capture the nonlinear dynamics of the series and exogenous variables. The package is useful for analyzing economic and financial time series data that exhibit both long-term trends and short-term fluctuations. This package has been developed using algorithm of Jammazi et al. <doi:10.1016/j.intfin.2014.11.011>.

This package provides new types of omnibus tests which are generally much more powerful than traditional tests (including the Kolmogorov-Smirnov, Cramer-von Mises and Anderson-Darling tests),see Zhang (2002) <doi:10.1111/1467-9868.00337>.

It is used to identify dysregulated pathways based on a pre-ranked gene pair list. A fast algorithm is used to make the computation really fast. The data in package DysPIAData is needed.

Dynamic slicing is a method designed for dependency detection between a categorical variable and a continuous variable. It could be applied for non-parametric hypothesis testing and gene set enrichment analysis.

S4 classes around infrastructure provided by the coda and dclone packages to make package development easy as a breeze with data cloning for hierarchical models.

This package provides methods for (auto)covariance/correlation function estimation in change point regression with stationary errors circumventing the pre-estimation of the underlying signal of the observations. Generic, first-order, (m+1)-gapped, difference-based autocovariance function estimator is based on M. Levine and I. Tecuapetla-Gómez (2023) <doi:10.48550/arXiv.1905.04578>. Bias-reducing, second-order, (m+1)-gapped, difference-based estimator is based on I. Tecuapetla-Gómez and A. Munk (2017) <doi:10.1111/sjos.12256>. Robust autocovariance estimator for change point regression with autoregressive errors is based on S. Chakar et al. (2017) <doi:10.3150/15-BEJ782>. It also includes a general projection-based method for covariance matrix estimation.

Bayesian networks with continuous and/or discrete variables can be learned and compared from data. The method is described in Boettcher and Dethlefsen (2003), <doi:10.18637/jss.v008.i20>.

Piecewise linear segmentation of ordered data by a dynamic programming algorithm. The algorithm was developed for time series data, e.g. growth curves, and for genome-wide read-count data from next generation sequencing, but is broadly applicable. Generic implementations of dynamic programming routines allow to scan for optimal segmentation parameters and test custom segmentation criteria ("scoring functions").

The Ditwah storm began impacting Sri Lanka on 25 November 2025. Ditwah provides a collection of tidy, well-structured datasets to support storm data management, monitoring, and early warning applications in Sri Lanka. The publicly available data were converted to tidy data format for easy analysis. The package processes weather data, flood data and situation report data (families affected, etc.). The package also includes functions for analyzing river level progression and load dashboard visualizations to enhance situational awareness. This is also developed for educational purposes to support learning in data wrangling, visualization, and disaster analytics.

This package provides functions for direct surrogate variable analysis, which can identify hidden factors in high-dimensional biomedical data.

Cancer genomes contain large numbers of somatic alterations but few genes drive tumor development. Identifying cancer driver genes is critical for precision oncology. Most of current approaches either identify driver genes based on mutational recurrence or using estimated scores predicting the functional consequences of mutations. driveR is a tool for personalized or batch analysis of genomic data for driver gene prioritization by combining genomic information and prior biological knowledge. As features, driveR uses coding impact metaprediction scores, non-coding impact scores, somatic copy number alteration scores, hotspot gene/double-hit gene condition, phenolyzer gene scores and memberships to cancer-related KEGG pathways. It uses these features to estimate cancer-type-specific probability for each gene of being a cancer driver using the related task of a multi-task learning classification model. The method is described in detail in Ulgen E, Sezerman OU. 2021. driveR: driveR: a novel method for prioritizing cancer driver genes using somatic genomics data. BMC Bioinformatics <doi:10.1186/s12859-021-04203-7>.