Maximum likelihood estimation of nonlinear mixed effects models of epidemic growth using Template Model Builder ('TMB'). Enables joint estimation for collections of disease incidence time series, including time series that describe multiple epidemic waves. Supports a set of widely used phenomenological models: exponential, logistic, Richards (generalized logistic), subexponential, and Gompertz. Provides methods for interrogating model objects and several auxiliary functions, including one for computing basic reproduction numbers from fitted values of the initial exponential growth rate. Preliminary versions of this software were applied in Ma et al. (2014) <doi:10.1007/s11538-013-9918-2> and in Earn et al. (2020) <doi:10.1073/pnas.2004904117>.

Current layout algorithms such as Kamada Kawai do not take into consideration disjoint clusters in a network, often resulting in a high overlap among the clusters, resulting in a visual â hairballâ that often is uninterpretable. The ExplodeLayout algorithm takes as input (1) an edge list of a unipartite or bipartite network, (2) node layout coordinates (x, y) generated by a layout algorithm such as Kamada Kawai, (3) node cluster membership generated from a clustering algorithm such as modularity maximization, and (4) a radius to enable the node clusters to be â explodedâ to reduce their overlap. The algorithm uses these inputs to generate new layout coordinates of the nodes which â explodesâ the clusters apart, such that the edge lengths within the clusters are preserved, while the edge lengths between clusters are recalculated. The modified network layout with nodes and edges are displayed in two dimensions. The user can experiment with different explode radii to generate a layout which has sufficient separation of clusters, while reducing the overall layout size of the network. This package is a basic version of an earlier version called [epl]<https://github.com/UTMB-DIVA-Lab/epl> that searched for an optimal explode radius, and offered multiple ways to separate clusters in a network (Bhavnani et al(2017) <https://pmc.ncbi.nlm.nih.gov/articles/PMC5543384/>). The example dataset is for a bipartite network, but the algorithm can work also for unipartite networks.

This SVG elements generator can easily generate SVG elements such as rect, line, circle, ellipse, polygon, polyline, text and group. Also, it can combine and output SVG elements into a SVG file.

Analyzing censored variables usually requires the use of optimization algorithms. This package provides an alternative algebraic approach to the task of determining the expected value of a random censored variable with a known censoring point. Likewise this approach allows for the determination of the censoring point if the expected value is known. These results are derived under the assumption that the variable follows an Epanechnikov kernel distribution with known mean and range prior to censoring. Statistical functions related to the uncensored Epanechnikov distribution are also provided by this package.

By overloading the R help() function, this package allows users to use "docstring" style comments within their own defined functions. The package also provides additional functions to mimic the R basic example() function and the prototyping of packages.

Because fungicide resistance is an important phenotypic trait for fungi and oomycetes, it is necessary to have a standardized method of statistically analyzing the Effective Concentration (EC) values. This package is designed for those who are not terribly familiar with R to be able to analyze and plot an entire set of isolates using the drc package.

Support functions for R-based "EQUALencrypt - Encrypt and decrypt whole files" and "EQUALencrypt - Encrypt and decrypt columns of data" shiny applications which allow researchers without coding skills or expertise in encryption algorithms to share data after encryption. Gurusamy,K (2025)<doi:10.5281/zenodo.16743676> and Gurusamy,K (2025)<doi:10.5281/zenodo.16744058>.

This package provides statistical and visualization tools for the analysis of demographic indicators, and spatio-temporal behavior and characterization of outbreaks of vector-borne diseases (VBDs) in Colombia. It implements travel times estimated in Bravo-Vega C., Santos-Vega M., & Cordovez J.M. (2022), and the endemic channel method (Bortman, M. (1999) <https://iris.paho.org/handle/10665.2/8562>).

This package provides a collection of functions that allows for easy and consistent use of environment variables. This includes setting, checking, retrieving, transforming, and validating values stored in environment variables.

Fits a state-space mass-balance model for marine ecosystems, which implements dynamics derived from Ecopath with Ecosim ('EwE') <https://ecopath.org/> while fitting to time-series of fishery catch, biomass indices, age-composition samples, and weight-at-age data. Ecostate fits biological parameters (e.g., equilibrium mass) and measurement parameters (e.g., catchability coefficients) jointly with residual variation in process errors, and can include Bayesian priors for parameters.

Fits Leroux model in spectral domain to estimate causal spatial effect as detailed in Guan, Y; Page, G.L.; Reich, B.J.; Ventrucci, M.; Yang, S; (2020) <arXiv:2012.11767>. Both the parametric and semi-parametric models are available. The semi-parametric model relies on INLA'. The INLA package can be obtained from <https://www.r-inla.org/>.

Empirical likelihood (EL) inference for two-sample problems. The following statistics are included: the difference of two-sample means, smooth Huber estimators, quantile (qdiff) and cumulative distribution functions (ddiff), probability-probability (P-P) and quantile-quantile (Q-Q) plots as well as receiver operating characteristic (ROC) curves. EL calculations are based on J. Valeinis, E. Cers (2011) <http://home.lu.lv/~valeinis/lv/petnieciba/EL_TwoSample_2011.pdf>.

This package provides unsupervised selection and clustering of microarray data using mixture models. Following the methods described in McLachlan, Bean and Peel (2002) <doi:10.1093/bioinformatics/18.3.413> a subset of genes are selected based one the likelihood ratio statistic for the test of one versus two components when fitting mixtures of t-distributions to the expression data for each gene. The dimensionality of this gene subset is further reduced through the use of mixtures of factor analyzers, allowing the tissue samples to be clustered by fitting mixtures of normal distributions.

An implementation for using efficient initials to compute the maximal eigenpair in R. It provides three algorithms to find the efficient initials under two cases: the tridiagonal matrix case and the general matrix case. Besides, it also provides two algorithms for the next to the maximal eigenpair under these two cases.

To run data analysis for enzyme-link immunosorbent assays (ELISAs). Either the five- or four-parameter logistic model will be fitted for data of single ELISA. Moreover, the batch effect correction/normalization will be carried out, when there are more than one batches of ELISAs. Feng (2018) <doi:10.1101/483800>.

Collection of functions to evaluate uncertainty of results from water quality analysis using the Weighted Regressions on Time Discharge and Season (WRTDS) method. This package is an add-on to the EGRET package that performs the WRTDS analysis. The WRTDS modeling method was initially introduced and discussed in Hirsch et al. (2010) <doi:10.1111/j.1752-1688.2010.00482.x>, and expanded in Hirsch and De Cicco (2015) <doi:10.3133/tm4A10>. The paper describing the uncertainty and confidence interval calculations is Hirsch et al. (2015) <doi:10.1016/j.envsoft.2015.07.017>.

Exploring time series for signal detection. It is specifically designed to detect possible outbreaks using infectious disease surveillance data at the European Union / European Economic Area or country level. Automatic detection tools used are presented in the paper "Monitoring count time series in R: aberration detection in public health surveillance", by Salmon (2016) <doi:10.18637/jss.v070.i10>. The package includes: - Signal Detection tool, an interactive shiny application in which the user can import external data and perform basic signal detection analyses; - An automated report in HTML format, presenting the results of the time series analysis in tables and graphs. This report can also be stratified by population characteristics (see Population variable). This project was funded by the European Centre for Disease Prevention and Control.

Package provides a set of tools for robust estimation and inference for probit model with endogenous covariates. The current version contains a robust two-step estimator. For technical details, see Naghi, Varadi and Zhelonkin (2022), <doi:10.1016/j.ecosta.2022.05.001>.

Reads EXIF data using ExifTool <https://exiftool.org> and returns results as a data frame. ExifTool is a platform-independent Perl library plus a command-line application for reading, writing and editing meta information in a wide variety of files. ExifTool supports many different metadata formats including EXIF, GPS, IPTC, XMP, JFIF, GeoTIFF, ICC Profile, Photoshop IRB, FlashPix, AFCP and ID3, as well as the maker notes of many digital cameras by Canon, Casio, FLIR, FujiFilm, GE, HP, JVC/Victor, Kodak, Leaf, Minolta/Konica-Minolta, Motorola, Nikon, Nintendo, Olympus/Epson, Panasonic/Leica, Pentax/Asahi, Phase One, Reconyx, Ricoh, Samsung, Sanyo, Sigma/Foveon and Sony.

Survival analysis is employed to model time-to-event data. This package examines the relationship between survival and one or more predictors, termed as covariates, which can include both treatment variables (e.g., season of birth, represented by indicator functions) and continuous variables. To this end, the Cox-proportional hazard (Cox-PH) model, introduced by Cox in 1972, is a widely applicable and commonly used method for survival analysis. This package enables the estimation of the effect of randomization for the treatment variable to account for potential confounders, providing adjustment when estimating the association with exposure. It accommodates both fixed and time-dependent covariates and computes survival probabilities for lactation periods in dairy animals. The package is built upon the algorithm developed by Klein and Moeschberger (2003) <DOI:10.1007/b97377>.

This package provides computational methods for detecting adverse high-order drug interactions from individual case safety reports using statistical techniques, allowing the exploration of higher-order interactions among drug cocktails.

This package provides utility functions for standardizing economic entity (economy, aggregate, institution, etc.) name and id in economic datasets such as those published by the International Monetary Fund and World Bank. Aims to facilitate consistent data analysis, reporting, and joining across datasets. Used as a foundational building block in the EconDataverse family of packages (<https://www.econdataverse.org>).

An implementation of the quantitative ethnobotany indices in R. The goal is to provide an easy-to-use platform for ethnobotanists to assess the cultural significance of plant species based on informant consensus. The package closely follows the paper by Tardio and Pardo-de-Santayana (2008). Tardio, J., and M. Pardo-de-Santayana, 2008. Cultural Importance Indices: A Comparative Analysis Based on the Useful Wild Plants of Southern Cantabria (Northern Spain) 1. Economic Botany, 62(1), 24-39. <doi:10.1007/s12231-007-9004-5>.

This package provides functions for the echelon analysis proposed by Myers et al. (1997) <doi:10.1023/A:1018518327329>, and the detection of spatial clusters using echelon scan method proposed by Kurihara (2003) <doi:10.20551/jscswabun.15.2_171>.