This package implements distributional cost-effectiveness analysis (DCEA) as described in Cookson et al. (2020, ISBN:9780198838197) and the methods endorsed by NICE (2025) for health technology evaluation. Provides functions for both aggregate and full-form DCEA, inequality measurement (Atkinson index, Gini coefficient, slope index of inequality, relative index of inequality), social welfare function evaluation, equity-efficiency impact plane visualisation, and sensitivity analysis over inequality aversion parameters. Includes baseline health distributions for England (by IMD quintile), Canada (income quintile), and global WHO regions. Suitable for academic research, health technology assessment submissions, and public health policy analysis.

This package provides a `.` object which can be used for unpacking assignments. For example, `.[rows, columns] <- dim(cars)` could be used to pull the number of rows and number of columns from `dim(cars)` into individual variables `rows` and `columns` in a single step.

The framework provides functions to generate ODEs of reaction networks, parameter transformations, observation functions, residual functions, etc. The framework follows the paradigm that derivative information should be used for optimization whenever possible. Therefore, all major functions produce and can handle expressions for symbolic derivatives. The methods used in dMod were published in Kaschek et al, 2019, <doi:10.18637/jss.v088.i10>.

Data whitening is a widely used preprocessing step to remove correlation structure since statistical models often assume independence. Here we use a probabilistic model of the observed data to apply a whitening transformation. This Gaussian Inverse Wishart Empirical Bayes model substantially reduces computational complexity, and regularizes the eigen-values of the sample covariance matrix to improve out-of-sample performance.

This package provides tools for downloading and processing microdata from the PNAD Contà nua (PNADC, Continuous National Household Sample Survey), a rotating panel survey published quarterly by IBGE (Brazilian Institute of Geography and Statistics). Includes panel identification algorithms for linking individuals across survey waves.

Measurement and partitioning of diversity, based on Tsallis entropy, following Marcon and Herault (2015) <doi:10.18637/jss.v067.i08>. divent provides functions to estimate alpha, beta and gamma diversity of communities, including phylogenetic and functional diversity.

Estimation of incidence and case fatality for a chronic disease, given partial information, using a multi-state model. Given data on age-specific mortality and either incidence or prevalence, Bayesian inference is used to estimate the posterior distributions of incidence, case fatality, and functions of these such as prevalence. The methods are described in Jackson et al. (2023) <doi:10.1093/jrsssa/qnac015>.

This package provides a statistically and computationally efficient debiasing method for conducting valid inference on the high-dimensional linear regression function with missing outcomes. The reference paper is Zhang, Giessing, and Chen (2023) <doi:10.48550/arXiv.2309.06429>.

DataSHIELD is an infrastructure and series of R packages that enables the remote and non-disclosive analysis of sensitive research data. This DataSHIELD Interface implementation is for analyzing datasets living in the current R session. The purpose of this is primarily for lightweight DataSHIELD analysis package development.

This R function implements the nonstationary Kriging model proposed by Tuo, Wu and Yu (2014) <DOI:10.1080/00401706.2013.842935> for analyzing multi-fidelity computer outputs. This function computes the maximum likelihood estimates for the model parameters as well as the predictive means and variances of the exact solution.

Useful functions for various DDI (Data Documentation Initiative) related inputs and outputs. Converts data files to and from DDI, SPSS, Stata, SAS, R and Excel, including user declared missing values.

This package provides a systematic biology tool was developed to repurpose drugs via a drug-drug functional similarity network. DrugSim2DR first predict drug-drug functional similarity in the context of specific disease, and then using the similarity constructed a weighted drug similarity network. Finally, it used a network propagation algorithm on the network to identify drugs with significant target abnormalities as candidate drugs.

This package provides functionality for users who are learning R or the techniques of data analysis. Written as a collection of wrapper functions, the DTwrapper package facilitates many core operations of data processing. This is achieved with relatively few requirements about the order of the processing steps or knowledge of specialized syntax. DTwrappers creates coding results along with translations to data.table's code. This enables users to benefit from the speed and efficiency of data.table's calculations. Furthermore, the package also provides the translated code for educational purposes so that users can review working examples of coding syntax and calculations.

Computations of Fisher's z-tests concerning different kinds of correlation differences. The diffpwr family entails approaches to estimating statistical power via Monte Carlo simulations. Important to note, the Pearson correlation coefficient is sensitive to linear association, but also to a host of statistical issues such as univariate and bivariate outliers, range restrictions, and heteroscedasticity (e.g., Duncan & Layard, 1973 <doi:10.1093/BIOMET/60.3.551>; Wilcox, 2013 <doi:10.1016/C2010-0-67044-1>). Thus, every power analysis requires that specific statistical prerequisites are fulfilled and can be invalid if the prerequisites do not hold. To this end, the bootcor family provides bootstrapping confidence intervals for the incorporated correlation difference tests.

Draws stylized choropleth maps -- hexagonal maps and triangular multiclass hex maps -- for New Zealand District Health Boards and Regional Council areas. These allow faceted, coloured displays of quantitative information for comparison across District Health Boards or Regional Councils. The preprint Lumley (2019) <arXiv:1912.04435> is based on the methods in this package.

Fit a mixture of Discrete Laplace distributions using plain numerical optimisation. This package has similar applications as the disclapmix package that uses an EM algorithm.

This package provides tools for converting and imputing date values to the ISO 8601 standard format and for reconciling differences between two versions of a data set. The package automatically detects date patterns within data frame columns and converts them to consistent ISO-formatted dates, with optional imputation of missing day or month components based on user-defined rules. It also includes functionality to identify inserted, deleted, and updated records, as well as column- and value-level changes, when comparing old and new versions of a data frame. Only one date format may be applied within a single column.

Estimates Two-way Fixed Effects difference-in-differences/event-study models using the imputation-based approach proposed by Borusyak, Jaravel, and Spiess (2021).

Geologic pattern data from <https://ngmdb.usgs.gov/fgdc_gds/geolsymstd.php>. Access functions are provided in the accompanying package deeptime'.

Independent component analysis based on distance correlation, including a robust variant using the bowl transformation. The package provides user-facing implementations of distance covariance and distance correlation, including memory-efficient blockwise computations for large data sets. It includes a sequential ICA estimator based on minimizing distance correlation, as well as tools for analyzing serial dependence via distance autocorrelation, dependograms, and permutation-based tests. In addition, it provides functions for testing serial dependence based on distance correlation and the Hilbertâ Schmidt independence criterion. The methodology is related to Matteson and Tsay (2017) <doi:10.1080/01621459.2016.1150851> and to the robust framework of Leyder et al. (2026) <doi:10.1007/s11634-026-00674-9>.

Fit logistic functions to observed dose-response continuous data and evaluate goodness-of-fit measures. See Malyutina A., Tang J., and Pessia A. (2023) <doi:10.18637/jss.v106.i04>.

This package provides a set of pricing and expository functions that should be useful in teaching a course on financial derivatives.

Scientific and technical article format for the web. Distill articles feature attractive, reader-friendly typography, flexible layout options for visualizations, and full support for footnotes and citations.

This package provides a unified framework to building Area Deprivation Index (ADI), Social Vulnerability Index (SVI), and Neighborhood Deprivation Index (NDI) deprivation measures and accessing related data from the U.S. Census Bureau such as Gini coefficient data. Tools are also available for calculating percentiles, quantiles, and for creating clear map breaks for data visualization.