This package provides tools for wrapping DataSHIELD analyses into RO-Crate (Research Object Crate) objects. Provides functions to create structured metadata for federated data analysis projects, enabling governance tracking of data access, project membership, analysis execution and output validation across distributed data sources.

This package provides a set of algorithms based on Quinn et al. (1991) <doi:10.1002/hyp.3360050106> for processing river network and digital elevation data to build implementations of Dynamic TOPMODEL, a semi-distributed hydrological model proposed in Beven and Freer (2001) <doi:10.1002/hyp.252>. The dynatop package implements simulation code for Dynamic TOPMODEL based on the output of dynatopGIS'.

This package provides a framework for the identification and analysis of Differentially Expressed Single Nucleotide Polymorphisms (deSNPs) using high-throughput sequencing data. It enables users to import SNP count data from variant files, perform allele-specific read count extraction, and statistically detect SNPs showing significant differences in allele expression between biological conditions or sample groups. This package contains tools for calculating SNP-index and Delta SNP-index from VCF-derived allele depth data with statistical testing and filtering, including sliding-window analysis of genomic regions.

This package performs an exploratory data analysis through a shiny interface. It includes basic methods such as the mean, median, mode, normality test, among others. It also includes clustering techniques such as Principal Components Analysis, Hierarchical Clustering and the K-Means Method.

Summarizes data frames by calculating various statistics including central tendency, dispersion, shape, and normality diagnostics. Handles numeric, character, and factor columns with NA-aware computations.

Access the Google Data Commons API V2 <https://docs.datacommons.org/api/rest/v2/>. Data Commons provides programmatic access to statistical and demographic data from dozens of sources organized in a knowledge graph.

Calculates key indicators such as fertility rates (Total Fertility Rate (TFR), General Fertility Rate (GFR), and Age Specific Fertility Rate (ASFR)) using Demographic and Health Survey (DHS) women/individual data, childhood mortality probabilities and rates such as Neonatal Mortality Rate (NNMR), Post-neonatal Mortality Rate (PNNMR), Infant Mortality Rate (IMR), Child Mortality Rate (CMR), and Under-five Mortality Rate (U5MR), and adult mortality indicators such as the Age Specific Mortality Rate (ASMR), Age Adjusted Mortality Rate (AAMR), Age Specific Maternal Mortality Rate (ASMMR), Age Adjusted Maternal Mortality Rate (AAMMR), Age Specific Pregnancy Related Mortality Rate (ASPRMR), Age Adjusted Pregnancy Related Mortality Rate (AAPRMR), Maternal Mortality Ratio (MMR) and Pregnancy Related Mortality Ratio (PRMR). In addition to the indicators, the DHS.rates package estimates sampling errors indicators such as Standard Error (SE), Design Effect (DEFT), Relative Standard Error (RSE) and Confidence Interval (CI). The package is developed according to the DHS methodology of calculating the fertility indicators and the childhood mortality rates outlined in the "Guide to DHS Statistics" (Croft, Trevor N., Aileen M. J. Marshall, Courtney K. Allen, et al. 2018, <https://dhsprogram.com/Data/Guide-to-DHS-Statistics/index.cfm>) and the DHS methodology of estimating the sampling errors indicators outlined in the "DHS Sampling and Household Listing Manual" (ICF International 2012, <https://dhsprogram.com/pubs/pdf/DHSM4/DHS6_Sampling_Manual_Sept2012_DHSM4.pdf>).

Graphical interface for loading datasets in RStudio from all installed (including unloaded) packages, also includes command line interfaces.

Estimation of distributed lag models (DLMs) based on a Bayesian additive regression trees framework. Includes several extensions of DLMs: treed DLMs and distributed lag mixture models (Mork and Wilson, 2023) <doi:10.1111/biom.13568>; treed distributed lag nonlinear models (Mork and Wilson, 2022) <doi:10.1093/biostatistics/kxaa051>; heterogeneous DLMs (Mork, et. al., 2024) <doi:10.1080/01621459.2023.2258595>; monotone DLMs (Mork and Wilson, 2024) <doi:10.1214/23-BA1412>. The package also includes visualization tools and a shiny interface to check model convergence and to help interpret results.

This package provides a management tool for specimen data ranging from public museum collections to private specimen repositories. The main types of data addressed are spatial (coordinates, longitude and latitude) and taxonomic data (ranking and nomenclature validity) with some additional options for user-determined dataset refinement. Combined or individual calls to the online repositories of the Global Biodiversity Information Facility (GBIF) via rgbif and the Integrated Taxonomic Information System (ITIS) via taxize enable built-in taxonomic checks.

This package provides a variety of methods to identify data quality issues in process-oriented data, which are useful to verify data quality in a process mining context. Builds on the class for activity logs implemented in the package bupaR'. Methods to identify data quality issues either consider each activity log entry independently (e.g. missing values, activity duration outliers,...), or focus on the relation amongst several activity log entries (e.g. batch registrations, violations of the expected activity order,...).

Data whitening is a widely used preprocessing step to remove correlation structure since statistical models often assume independence. Here we use a probabilistic model of the observed data to apply a whitening transformation. This Gaussian Inverse Wishart Empirical Bayes model substantially reduces computational complexity, and regularizes the eigen-values of the sample covariance matrix to improve out-of-sample performance.

This package provides a toolbox for descriptive statistics, based on the computation of frequency and contingency tables. Several statistical functions and plot methods are provided to describe univariate or bivariate distributions of factors, integer series and numerical series either provided as individual values or as bins.

Analysis of agreement for nominal data between two raters using the Delta model. This model is proposed as an alternative to the widespread measure Cohen kappa coefficient, which performs poorly when the marginal distributions are very asymmetric (Martin-Andres and Femia-Marzo (2004), <doi:10.1348/000711004849268>; Martin-Andres and Femia-Marzo (2008) <doi:10.1080/03610920701669884>). The package also contains a function to perform a massive analysis of multiple raters against a gold standard. A shiny app is also provided to obtain the measures of nominal agreement between two raters.

Supporting the quantitative analysis of binary welfare based decision making processes using Monte Carlo simulations. Decision support is given on two levels: (i) The actual decision level is to choose between two alternatives under probabilistic uncertainty. This package calculates the optimal decision based on maximizing expected welfare. (ii) The meta decision level is to allocate resources to reduce the uncertainty in the underlying decision problem, i.e to increase the current information to improve the actual decision making process. This problem is dealt with using the Value of Information Analysis. The Expected Value of Information for arbitrary prospective estimates can be calculated as well as Individual Expected Value of Perfect Information. The probabilistic calculations are done via Monte Carlo simulations. This Monte Carlo functionality can be used on its own.

An implementation by Chen, Li, and Zhang (2022) <doi: 10.1093/bioadv/vbac041> of the Depth Importance in Precision Medicine (DIPM) method in Chen and Zhang (2022) <doi:10.1093/biostatistics/kxaa021> and Chen and Zhang (2020) <doi:10.1007/978-3-030-46161-4_16>. The DIPM method is a classification tree that searches for subgroups with especially poor or strong performance in a given treatment group.

Manage your source code dependencies by decorating your existing R code with special, roxygen'-style comments.

This package provides a revision to the stats::ks.test() function and the associated ks.test.Rd help page. With one minor exception, it does not change the existing behavior of ks.test(), and it adds features necessary for doing one-sample tests with hypothesized discrete distributions. The package also contains cvm.test(), for doing one-sample Cramer-von Mises goodness-of-fit tests.

High-frequency time-series support via nanotime and data.table'.

Diffusion Weighted Imaging (DWI) is a Magnetic Resonance Imaging modality, that measures diffusion of water in tissues like the human brain. The package contains R-functions to process diffusion-weighted data. The functionality includes diffusion tensor imaging (DTI), diffusion kurtosis imaging (DKI), modeling for high angular resolution diffusion weighted imaging (HARDI) using Q-ball-reconstruction and tensor mixture models, several methods for structural adaptive smoothing including POAS and msPOAS, and a streamline fiber tracking for tensor and tensor mixture models. The package provides functionality to manipulate and visualize results in 2D and 3D.

Dynamic model averaging for binary and continuous outcomes.

In-line functions for multivariate optimization via desirability functions (Derringer and Suich, 1980, <doi:10.1080/00224065.1980.11980968>) with easy use within dplyr pipelines.

Load configuration from a .env file, that is in the current working directory, into environment variables.

DataSHIELD is an infrastructure and series of R packages that enables the remote and non-disclosive analysis of sensitive research data. This package is the DataSHIELD interface implementation to analyze data shared on a MOLGENIS Armadillo server. MOLGENIS Armadillo is a light-weight DataSHIELD server using a file store and an RServe server.