This package provides a flexible tool for enrichment analysis based on user-defined sets. It allows users to perform over-representation analysis of the custom sets among any specified ranked feature list, hence making enrichment analysis applicable to various types of data from different scientific fields. EnrichIntersect also enables an interactive means to visualize identified associations based on, for example, the mix-lasso model (Zhao et al., 2022 <doi:10.1016/j.isci.2022.104767>) or similar methods.

This package provides functions for estimating plant pathogen parameters from access period (AP) experiments. Separate functions are implemented for semi-persistently transmitted (SPT) and persistently transmitted (PT) pathogens. The common AP experiment exposes insect cohorts to infected source plants, healthy test plants, and intermediate plants (for PT pathogens). The package allows estimation of acquisition and inoculation rates during feeding, recovery rates, and latent progression rates (for PT pathogens). Additional functions support inference of epidemic risk from pathogen and local parameters, and also simulate AP experiment data. The functions implement probability models for epidemiological analysis, as derived in Donnelly et al. (2025), <doi:10.32942/X29K9P>. These models were originally implemented in the EpiPv GitHub package.

This package provides a variety of methods are provided to estimate and visualize distributional differences in terms of effect sizes. Particular emphasis is upon evaluating differences between two or more distributions across the entire scale, rather than at a single point (e.g., differences in means). For example, Probability-Probability (PP) plots display the difference between two or more distributions, matched by their empirical CDFs (see Ho and Reardon, 2012; <doi:10.3102/1076998611411918>), allowing for examinations of where on the scale distributional differences are largest or smallest. The area under the PP curve (AUC) is an effect-size metric, corresponding to the probability that a randomly selected observation from the x-axis distribution will have a higher value than a randomly selected observation from the y-axis distribution. Binned effect size plots are also available, in which the distributions are split into bins (set by the user) and separate effect sizes (Cohen's d) are produced for each bin - again providing a means to evaluate the consistency (or lack thereof) of the difference between two or more distributions at different points on the scale. Evaluation of empirical CDFs is also provided, with built-in arguments for providing annotations to help evaluate distributional differences at specific points (e.g., semi-transparent shading). All function take a consistent argument structure. Calculation of specific effect sizes is also possible. The following effect sizes are estimable: (a) Cohen's d, (b) Hedges g, (c) percentage above a cut, (d) transformed (normalized) percentage above a cut, (e) area under the PP curve, and (f) the V statistic (see Ho, 2009; <doi:10.3102/1076998609332755>), which essentially transforms the area under the curve to standard deviation units. By default, effect sizes are calculated for all possible pairwise comparisons, but a reference group (distribution) can be specified.

This is a collection of assorted functions and examples collected from various projects. Currently we have functionalities for simplifying overlapping time intervals, Charlson comorbidity score constructors for Danish data, getting frequency for multiple variables, getting standardized output from logistic and log-linear regressions, sibling design linear regression functionalities a method for calculating the confidence intervals for functions of parameters from a GLM, Bayes equivalent for hypothesis testing with asymptotic Bayes factor, and several help functions for generalized random forest analysis using grf'.

Experiences studies are an integral component of the actuarial control cycle. Regardless of the decrement or policyholder behavior of interest, the analyses conducted is often the same. Ultimately, this package aims to reduce time spent writing the same code used for different experience studies, therefore increasing the time for to uncover new insights inherit within the relevant experience.

Expert Algorithm Verbal Autopsy assigns causes of death to 2016 WHO Verbal Autopsy Questionnaire data. odk2EAVA() converts data to a standard input format for cause of death determination building on the work of Thomas (2021) <https://cran.r-project.org/src/contrib/Archive/CrossVA/>. codEAVA() uses the presence and absence of signs and symptoms reported in the Verbal Autopsy interview to diagnose common causes of death. A deterministic algorithm assigns a single cause of death to each Verbal Autopsy interview record using a hierarchy of all common causes for neonates or children 1 to 59 months of age.

Maximum likelihood estimation of nonlinear mixed effects models of epidemic growth using Template Model Builder ('TMB'). Enables joint estimation for collections of disease incidence time series, including time series that describe multiple epidemic waves. Supports a set of widely used phenomenological models: exponential, logistic, Richards (generalized logistic), subexponential, and Gompertz. Provides methods for interrogating model objects and several auxiliary functions, including one for computing basic reproduction numbers from fitted values of the initial exponential growth rate. Preliminary versions of this software were applied in Ma et al. (2014) <doi:10.1007/s11538-013-9918-2> and in Earn et al. (2020) <doi:10.1073/pnas.2004904117>.

Import data from Epidata XML files .epx and convert it to R data structures.

EM algorithms and several efficient initialization methods for model-based clustering of finite mixture Gaussian distribution with unstructured dispersion in both of unsupervised and semi-supervised learning.

An interface for performing climate matching using the Euclidean "Climatch" algorithm. Functions provide a vector of climatch scores (0-10) for each location (i.e., grid cell) within the recipient region, the percent of climatch scores >= a threshold value, and mean climatch score. Tools for parallelization and visualizations are also provided. Note that the floor function that rounds the climatch score down to the nearest integer has been removed in this implementation and the â Climatchâ algorithm, also referred to as the â Climateâ algorithm, is described in: Crombie, J., Brown, L., Lizzio, J., & Hood, G. (2008). â Climatch user manualâ . The method for the percent score is described in: Howeth, J.G., Gantz, C.A., Angermeier, P.L., Frimpong, E.A., Hoff, M.H., Keller, R.P., Mandrak, N.E., Marchetti, M.P., Olden, J.D., Romagosa, C.M., and Lodge, D.M. (2016). <doi:10.1111/ddi.12391>.

This package creates simple or stacked epidemic curves for hourly, daily, weekly or monthly outcome data.

This package provides statistical and visualization tools for the analysis of demographic indicators, and spatio-temporal behavior and characterization of outbreaks of vector-borne diseases (VBDs) in Colombia. It implements travel times estimated in Bravo-Vega C., Santos-Vega M., & Cordovez J.M. (2022), and the endemic channel method (Bortman, M. (1999) <https://iris.paho.org/handle/10665.2/8562>).

EB-PRS is a novel method that leverages information for effect sizes across all the markers to improve the prediction accuracy. No parameter tuning is needed in the method, and no external information is needed. This R-package provides the calculation of polygenic risk scores from the given training summary statistics and testing data. We can use EB-PRS to extract main information, estimate Empirical Bayes parameters, derive polygenic risk scores for each individual in testing data, and evaluate the PRS according to AUC and predictive r2. See Song et al. (2020) <doi:10.1371/journal.pcbi.1007565> for a detailed presentation of the method.

Perform a Bayesian estimation of the exploratory deterministic input, noisy and gate (EDINA) cognitive diagnostic model described by Chen et al. (2018) <doi:10.1007/s11336-017-9579-4>.

This package provides methods to deal with the free antiassociative algebra over the reals with an arbitrary number of indeterminates. Antiassociativity means that (xy)z = -x(yz). Antiassociative algebras are nilpotent with nilindex four (Remm, 2022, <doi:10.48550/arXiv.2202.10812>) and this drives the design and philosophy of the package. Methods are defined to create and manipulate arbitrary elements of the antiassociative algebra, and to extract and replace coefficients. A vignette is provided.

Software accompanying Gary King's book: A Solution to the Ecological Inference Problem. (1997). Princeton University Press. ISBN 978-0691012407.

This package provides easy access to tidy education finance data using Bellwether's methodology to combine NCES F-33 Survey, Census Bureau Small Area Income Poverty Estimates (SAIPE), and community data from the ACS 5-Year Estimates. The package simplifies downloading, caching, and filtering education finance data by year and state, enabling researchers and analysts to explore K-12 education funding patterns, revenue sources, expenditure categories, and demographic factors across U.S. school districts.

This package provides tools for integrated sensitivity analysis of evidence factors in observational studies. When an observational study allows for multiple independent or nearly independent inferences which, if vulnerable, are vulnerable to different biases, we have multiple evidence factors. This package provides methods that respect type I error rate control. Examples are provided of integrated evidence factors analysis in a longitudinal study with continuous outcome and in a case-control study. Karmakar, B., French, B., and Small, D. S. (2019)<DOI:10.1093/biomet/asz003>.

Reads, writes, and edits EXIF and other file metadata using ExifTool <https://exiftool.org/>, returning read results as a data frame. ExifTool supports many different metadata formats including EXIF, GPS, IPTC, XMP, JFIF, GeoTIFF, ICC Profile, Photoshop IRB, FlashPix, AFCP and ID3, Lyrics3, as well as the maker notes of many digital cameras by Canon, Casio, DJI, FLIR, FujiFilm, GE, GoPro, HP, JVC/Victor, Kodak, Leaf, Minolta/Konica-Minolta, Motorola, Nikon, Nintendo, Olympus/Epson, Panasonic/Leica, Pentax/Asahi, Phase One, Reconyx, Ricoh, Samsung, Sanyo, Sigma/Foveon and Sony.

Exploratory principal component analysis for large-scale dataset, including sparse principal component analysis and sparse matrix approximation.

Fast and easy computation of Euclidean Minimum Spanning Trees (EMST) from data, relying on the R API for mlpack - the C++ Machine Learning Library (Curtin et. al., 2013). emstreeR uses the Dual-Tree Boruvka (March, Ram, Gray, 2010, <doi:10.1145/1835804.1835882>), which is theoretically and empirically the fastest algorithm for computing an EMST. This package also provides functions and an S3 method for readily visualizing Minimum Spanning Trees (MST) using either the style of the base', scatterplot3d', or ggplot2 libraries; and functions to export the MST output to shapefiles.

Implementation of the Centre of Gravity method and the Extrapolated Centre of Gravity method. It supports replicated observations. Cameron, D.G., et al (1982) <doi:10.1366/0003702824638610> JCGM (2008) <doi:10.59161/JCGM100-2008E>.

Fits a variety of hidden Markov models, structured in an extended generalized linear model framework. See T. Rolf Turner, Murray A. Cameron, and Peter J. Thomson (1998) <doi:10.2307/3315677>, and Rolf Turner (2008) <doi:10.1016/j.csda.2008.01.029> and the references cited therein.

Some utility functions for validation and data manipulation. These functions can be helpful to reduce internal codes everywhere in package development.