This package provides tools to conduct Bayesian multivariate network meta-analysis providing - the single correlation coefficient model by Efthimiou et al. (2015) <doi:10.1093/biostatistics/kxu030>; - per-outcome treatment hierarchies using the surface under the cumulative ranking curve (SUCRA), the probability of best value, or median (or mean) ranks (Salanti et al., 2011) <doi:10.1016/j.jclinepi.2010.03.016>; - across-outcomes benefit-risk assessment using the ViÅ¡eKriterijumska Optimizacija I Kompromisno ReÅ¡enje (VIKOR) method (Opricovic & Tzeng, 2004) <doi:10.1016/S0377-2217(03)00020-1>; - convergence checks using trace plots, density plots, or the R-hat statistic; - forest plots of treatment estimates, scatter plots of per-outcome rankings, Hasse diagrams (Carlsen & Bruggemann, 2014) <doi:10.1002/cem.2569> to visualize the partial order of the treatments across all outcomes.

This package implements bivariate and Multivariate Quantile-on-Quantile Granger causality tests building on the Quantile-on-Quantile regression framework of Sim and Zhou (2015) <doi:10.1016/j.jbankfin.2015.01.013> and the quantile Granger causality test of Troster (2018) <doi:10.1080/07474938.2016.1172400>. The bivariate test estimates the local-linear slope in the quantile regression of y_t on lagged x_t with lagged y_t as control, using Gaussian kernel weights, and tests it against zero by paired bootstrap. The multivariate (conditional) test additionally conditions on a set of moderators Z and optional x times Z interaction terms, in the spirit of Sinha, Ghosh, Hussain, Nguyen and Das (2023) <doi:10.1016/j.eneco.2023.107021>. A Sup-Wald summary across the quantile grid is also provided. Heatmaps and 3D surfaces default to the MATLAB Parula colour map.

This package provides a collection of helper functions for analyzing Second Primary Cancer data, including functions to reshape data, to calculate patient states and analyze cancer incidence.

This package provides a comprehensive toolkit for conducting Multilevel Analysis of Individual Heterogeneity and Discriminatory Accuracy (MAIHDA). Methods are described in Merlo (2018) <doi:10.1016/j.socscimed.2017.12.026> and Evans et al. (2018) <doi:10.1016/j.socscimed.2017.11.011>. Automatically generates intersectional strata, fits analytical models, extracts statistics, and produces visualizations.

This package implements functional principal component analysis (FPCA) for univariate and multivariate sparse functional data. The package estimates eigenfunctions, eigenvalues, and error variance simultaneously via maximum likelihood estimation (MLE), using a spline basis representation of the eigenfunctions. Orthonormality of the estimated eigenfunctions is enforced through a modified Gram-Schmidt (MGS) orthogonalization procedure applied iteratively during estimation, avoiding direct optimization over the Stiefel manifold and improving numerical stability. The optimal number of basis functions and principal components is selected via an Akaike Information Criterion (AIC)-type criterion, supporting both a full grid-search strategy and a computationally efficient sequential selection approach. Principal component scores are estimated by conditional expectation, enabling reconstruction of individual trajectories over the entire domain from sparse observations. Pointwise confidence intervals for reconstructed trajectories are also provided. Methods are described in Mbaka, Cao and Carey (2026) <doi:10.48550/arXiv.2603.18833> and Mbaka and Carey (2026) <doi:10.48550/arXiv.2603.19799>.

Access to different Spanish meteorological stations data services and APIs (AEMET, SMC, MG, Meteoclimatic...).

Encodes several methods for performing Mendelian randomization analyses with summarized data. Similar to the MendelianRandomization package, but with fewer bells and whistles, and less frequent updates. As described in Yavorska (2017) <doi:10.1093/ije/dyx034> and Broadbent (2020) <doi:10.12688/wellcomeopenres.16374.2>.

Multi-omic (or any multi-view) spectral clustering methods often assume the same number of clusters across all datasets. We supply methods for multi-omic spectral clustering when the number of distinct clusters differs among the omics profiles (views).

Allows the user to estimate transition probabilities for migratory animals between any two phases of the annual cycle, using a variety of different data types. Also quantifies the strength of migratory connectivity (MC), a standardized metric to quantify the extent to which populations co-occur between two phases of the annual cycle. Includes functions to estimate MC and the more traditional metric of migratory connectivity strength (Mantel correlation) incorporating uncertainty from multiple sources of sampling error. For cross-species comparisons, methods are provided to estimate differences in migratory connectivity strength, incorporating uncertainty. See Cohen et al. (2018) <doi:10.1111/2041-210X.12916>, Cohen et al. (2019) <doi:10.1111/ecog.03974>, Roberts et al. (2023) <doi:10.1002/eap.2788>, and Hostetler et al. (2025) <doi:10.1111/2041-210X.14467> for details on some of these methods.

Read a table of fixed width formatted data of different types into a data.frame for each type.

This package creates interactive maps using MapLibre GL and deck.gl via htmlwidgets'. Provides GPU-accelerated layers for points, lines and polygons, plus linked user interface components such as filters, views and summary cards for exploratory analysis and production dashboards.

Computes densities, probabilities, and random deviates of the Matrix Normal (Pocuca et al. (2019) <doi:10.48550/arXiv.1910.02859>). Also includes simple but useful matrix functions. See the vignette for more information.

Various kinds of plots (observations, variables, correlations, weights, regression coefficients and Variable Importance in the Projection) and aids to interpretation (coefficients, Q2, correlations, redundancies) for partial least squares regressions computed with the pls package, following Tenenhaus (1998, ISBN:2-7108-0735-1).

Estimation of treatment hierarchies in network meta-analysis using a novel frequentist approach based on treatment choice criteria (TCC) and probabilistic ranking models, as described by Evrenoglou et al. (2024) <DOI:10.48550/arXiv.2406.10612>. The TCC are defined using a rule based on the smallest worthwhile difference (SWD). Using the defined TCC, the NMA estimates (i.e., treatment effects and standard errors) are first transformed into treatment preferences, indicating either a treatment preference (e.g., treatment A > treatment B) or a tie (treatment A = treatment B). These treatment preferences are then synthesized using a probabilistic ranking model, which estimates the latent ability parameter of each treatment and produces the final treatment hierarchy. This parameter represents each treatments ability to outperform all the other competing treatments in the network. Here the terms ability to outperform indicates the propensity of each treatment to yield clinically important and beneficial effects when compared to all the other treatments in the network. Consequently, larger ability estimates indicate higher positions in the ranking list.

Calculate the maximal fat oxidation, the exercise intensity that elicits the maximal fat oxidation and the SIN model to represent the fat oxidation kinetics. Three variables can be obtained from the SIN model: dilatation, symmetry and translation. Examples of these methods can be found in Montes de Oca et al (2021) <doi:10.1080/17461391.2020.1788650> and Chenevière et al. (2009) <doi:10.1249/MSS.0b013e31819e2f91>.

Framework for the Item Response Theory analysis of dichotomous and ordinal polytomous outcomes under the assumption of within-item multidimensionality and discreteness of the latent traits. The fitting algorithms allow for missing responses and for different item parametrizations and are based on the Expectation-Maximization paradigm. Individual covariates affecting the class weights may be included in the new version together with possibility of constraints on all model parameters.

Multi modality data matrices are factorized conjointly into the multiplication of a shared sub-matrix and multiple modality specific sub-matrices, group sparse constraint is applied to the shared sub-matrix to capture the homogeneous and heterogeneous information, respectively. Then the samples are classified by clustering the shared sub-matrix with kmeanspp(), a new version of kmeans() developed here to obtain concordant results. The package also provides the cluster number estimation by rotation cost. Moreover, cluster specific features could be retrieved using hypergeometric tests.

Bayesian multivariate age-period-cohort (MAPC) models for analyzing health data, with support for model fitting, visualization, stratification, and model comparison. Inference focuses on identifiable cross-strata differences, as described by Riebler and Held (2010) <doi:10.1093/biostatistics/kxp037>. Methods for handling complex survey data via the survey package are included, as described in Mercer et al. (2014) <doi:10.1016/j.spasta.2013.12.001>.

Access the Red List of Montane Tree Species of the Tropical Andes Tejedor Garavito et al.(2014, ISBN:978-1-905164-60-8). This package allows users to search for globally threatened tree species within the andean montane forests, including cloud forests and seasonal (wet) forests above 1500 m a.s.l.

This package provides spatially survey balanced designs using the quasi-random number method described Robinson et al. (2013) <doi:10.1111/biom.12059> and adjusted in Robinson et al. (2017) <doi:10.1016/j.spl.2017.05.004>. Designs using MBHdesign can: 1) accommodate, without substantial detrimental effects on spatial balance, legacy sites (Foster et al., 2017 <doi:10.1111/2041-210X.12782>); 2) be based on points or transects (foster et al. 2020 <doi:10.1111/2041-210X.13321> and produce clustered samples (Foster et al. (in press). Additional information about the package use itself is given in Foster (2021) <doi:10.1111/2041-210X.13535>.

Package with multivariate analysis methodologies for experiment evaluation. The package estimates dissimilarity measures, builds dendrograms, obtains MANOVA, principal components, canonical variables, etc. (Pacote com metodologias de analise multivariada para avaliação de experimentos. O pacote estima medidas de dissimilaridade, construi de dendogramas, obtem a MANOVA, componentes principais, variaveis canonicas, etc.).

An open-source implementation of latent variable methods and multivariate modeling tools. The focus is on exploratory analyses using dimensionality reduction methods including low dimensional embedding, classical multivariate statistical tools, and tools for enhanced interpretation of machine learning methods (i.e. intelligible models to provide important information for end-users). Target domains include extension to dedicated applications e.g. for manufacturing process modeling, spectroscopic analyses, and data mining.

This package provides functions for estimating structural equation models using instrumental variables.

This package provides tools for multiscale systematic conservation planning using the H3 hierarchical hexagonal grid system (Uber Technologies (2024) <https://h3geo.org>) and the prioritizr package (Hanson et al. (2025) <doi:10.1111/cobi.14376>). Supports the definition and solution of conservation problems across nested H3 resolutions with resolution-specific features, costs, and management attributes, including cross-scale connectivity penalties derived from parent-child relationships. Also includes utilities to evaluate solutions using multiscale-aware diagnostics and to post-process optimization outputs into alternative area-targeted conservation scenarios.