Umbrella for the alabaster suite, providing a single-line import for all alabaster.* packages. Installing this package ensures that all known alabaster.* packages are also installed, avoiding problems with missing packages when a staging method or loading function is dynamically requested. Obviously, this comes at the cost of needing to install more packages, so advanced users and application developers may prefer to install the required alabaster.* packages individually.

This package can generate a synthetic map with reads covering the nucleosome regions as well as a synthetic map with forward and reverse reads emulating next-generation sequencing. The synthetic hybridization data of “Tiling Arrays” can also be generated. The user has choice between three different distributions for the read positioning: Normal, Student and Uniform. In addition, a visualization tool is provided to explore the synthetic nucleosome maps.

Dot plots of single-cell RNA-seq data allow for an examination of the relationships between cell groupings (e.g. clusters) and marker gene expression. The scDotPlot package offers a unified approach to perform a hierarchical clustering analysis and add annotations to the columns and/or rows of a scRNA-seq dot plot. It works with SingleCellExperiment and Seurat objects as well as data frames.

Differential expression analysis of RNA-seq using the Poisson-Tweedie (PT) family of distributions. PT distributions are described by a mean, a dispersion and a shape parameter and include Poisson and NB distributions, among others, as particular cases. An important feature of this family is that, while the Negative Binomial (NB) distribution only allows a quadratic mean-variance relationship, the PT distributions generalizes this relationship to any orde.

One and two sample mean and variance tests (differences and ratios) are considered. The test statistics are all expressed in the same form as the Student t-test, which facilitates their presentation in the classroom. This contribution also fills the gap of a robust (to non-normality) alternative to the chi-square single variance test for large samples, since no such procedure is implemented in standard statistical software.

This package provides the ability to display something analogous to Python's docstrings within R. By allowing the user to document their functions as comments at the beginning of their function without requiring putting the function into a package we allow more users to easily provide documentation for their functions. The documentation can be viewed just like any other help files for functions provided by packages as well.

Calculation and plotting of instantaneous unavailabilities of basic events along with the top event of fault trees are issues important in reliability analysis of complex systems. Here, a fault tree is provided in terms of its minimal cut sets, along with reliability and maintainability distribution functions of the basic events. All the methods are derived from Horton (2002, ISBN: 3-936150-21-4), Niloofar and Lazarova-Molnar (2022).

It provides an effective, efficient, and fast way to explore the Gene Ontology (GO). Given a set of genes, the package contains functions to assess the GO and obtain the terms associated with the genes and the levels of the GO terms. The package provides functions for the three different GO ontology. We discussed the methods explicitly in the following article <doi:10.1038/s41598-020-73326-3>.

This package provides utility functions that are simply, frequently used, but may require higher performance that what can be obtained from base R. Incidentally provides support for reverse geocoding', such as matching a point with its nearest neighbour in another array. Used as a complement to package hutils by sacrificing compilation or installation time for higher running speeds. The name is a portmanteau of the author and Rcpp'.

This package provides a systematic framework for integrating multiple modalities of assays profiled on the same set of samples. The goal is to identify genes that are altered in cancer either marginally or consistently across different assays. The heterogeneity among different platforms and different samples are automatically adjusted so that the overall alteration magnitude can be accurately inferred. See Tong and Coombes (2012) <doi:10.1093/bioinformatics/bts561>.

This package provides tools for easily and flexibly creating ggplot2 maps with inset maps. One crucial feature of maps is that they have fixed coordinate ratios, i.e., they cannot be distorted, which makes it difficult to manually place inset maps. This package provides functions to automatically position inset maps based on user-defined parameters, making it extremely easy to create maps with inset maps with minimal code.

This package provides a convenience tool to create HTML with inline styles using juicyjuice and markdown packages. It is particularly useful when working on a content management system (CMS) whose code editor eliminates style and link tags. The main use case of the package is the learning management system, Moodle'. Additional helper functions for teaching purposes are provided. Learn more about juicedown at <https://kenjisato.github.io/juicedown/>.

Estimate agreement of a group of raters with a gold standard rating on a nominal scale. For a single gold standard rater the average pairwise agreement of raters with this gold standard is provided. For a group of (gold standard) raters the approach of S. Vanbelle, A. Albert (2009) <doi:10.1007/s11336-009-9116-1> is implemented. Bias and standard error are estimated via delete-1 jackknife.

Clinical reporting figures require to use consistent colors and configurations. As a part of the Roche open-source clinical reporting project, namely the NEST project, the nestcolor package specifies the color code and default theme with specifying ggplot2 theme parameters. Users can easily customize color and theme settings before using the reset of NEST packages to ensure consistent settings in both static and interactive output at the downstream.

Clinical reports generated by Oncomine Reporter software contain critical data in unstructured PDF format, making manual extraction time-consuming and error-prone. ORscraper provides a coherent suite of functions to automate this process, allowing researchers to parse reports, identify key biomarkers, extract genetic variant tables, and filter results. It also integrates with the NCBI ClinVar API <https://www.ncbi.nlm.nih.gov/clinvar/> to enrich extracted data.

Use optimization to estimate weights that balance covariates for binary, multi-category, continuous, and multivariate treatments in the spirit of Zubizarreta (2015) <doi:10.1080/01621459.2015.1023805>. The degree of balance can be specified for each covariate. In addition, sampling weights can be estimated that allow a sample to generalize to a population specified with given target moments of covariates, as in matching-adjusted indirect comparison (MAIC).

Perform user-friendly power analyses for the random intercept cross-lagged panel model (RI-CLPM) and the bivariate stable trait autoregressive trait state (STARTS) model. The strategy as proposed by Mulder (2023) <doi:10.1080/10705511.2022.2122467> is implemented. Extensions include the use of parameter constraints over time, bounded estimation, generation of data with skewness and kurtosis, and the option to setup the power analysis for Mplus.

Consists of custom wrapper functions using packages openxlsx', flextable', and officer to create highly formatted MS office friendly output of your data frames. These viewer friendly outputs are intended to match expectations of professional looking presentations in business and consulting scenarios. The functions are opinionated in the sense that they expect the input data frame to have certain properties in order to take advantage of the automated formatting.

Quick Response codes (QR codes) are a type of matrix bar code and can be used to authenticate transactions, provide access to multi-factor authentication services and enable general data transfer in an image. QR codes use four standardized encoding modes (numeric, alphanumeric, byte/binary, and kanji) to efficiently store data. Matrix barcode generation is performed efficiently in C via the included libqrencoder library created by Kentaro Fukuchi.

This package provides a compilation of fish stock assessment methods for the analysis of length-frequency data in the context of data-poor fisheries. Includes methods and examples included in the FAO Manual by P. Sparre and S.C. Venema (1998), "Introduction to tropical fish stock assessment" (<https://openknowledge.fao.org/server/api/core/bitstreams/bc7c37b6-30df-49c0-b5b4-8367a872c97e/content>), as well as other more recent methods.

Bayesian analysis of item-level hierarchical twin data using an integrated item response theory model. Analyses are based on Schwabe & van den Berg (2014) <doi:10.1007/s10519-014-9649-7>, Molenaar & Dolan (2014) <doi:10.1007/s10519-014-9647-9>, Schwabe, Jonker & van den Berg (2016) <doi:10.1007/s10519-015-9768-9> and Schwabe, Boomsma & van den Berg (2016) <doi:10.1016/j.lindif.2017.01.018>.

This package provides significance tests for second-order stationarity for time series using bootstrap wavelet packet tests. Provides functionality to visualize the time series with the results of the hypothesis tests superimposed. The methodology is described in Cardinali, A and Nason, G P (2016) "Practical powerful wavelet packet tests for second-order stationarity." Applied and Computational Harmonic Analysis, 44, 558-585 <doi:10.1016/j.acha.2016.06.006>.

Find the location of the code for an R package based on the package's name or string representation. Checks on CRAN based on information in the URL field or BioConductor and GitHub based on constructing a URL, and verifies all paths via testing for a successful response. This can be useful when automating static code analysis based on a list of package names, and similar tasks.

This package provides a suite of tools to help modelers and decision-makers effectively interpret and communicate decision risk when evaluating multiple policy options. It uses model outputs from uncertainty analysis for baseline scenarios and policy alternatives to generate visual representations of uncertainty and quantitative measures for assessing associated risks. For more details see Wiggins and colleagues (2025) <doi:10.1371/journal.pone.0332522> and <https://dut.ihe.ca/>.