Analysis and visualization of plant disease progress curve data. Functions for fitting two-parameter population dynamics models (exponential, monomolecular, logistic and Gompertz) to proportion data for single or multiple epidemics using either linear or no-linear regression. Statistical and visual outputs are provided to aid in model selection. Synthetic curves can be simulated for any of the models given the parameters. See Laurence V. Madden, Gareth Hughes, and Frank van den Bosch (2007) <doi:10.1094/9780890545058> for further information on the methods.

Comparisons of floating point numbers are problematic due to errors associated with the binary representation of decimal numbers. Despite being aware of these problems, people still use numerical methods that fail to account for these and other rounding errors (this pitfall is the first to be highlighted in Circle 1 of Burns (2012) The R Inferno <https://www.burns-stat.com/pages/Tutor/R_inferno.pdf>). This package provides new relational operators useful for performing floating point number comparisons with a set tolerance.

This package provides classes and functions to calculate various distance measures and routes in heterogeneous geographic spaces represented as grids. The package implements measures to model dispersal histories first presented by van Etten and Hijmans (2010) <doi:10.1371/journal.pone.0012060>. Least-cost distances as well as more complex distances based on (constrained) random walks can be calculated. The distances implemented in the package are used in geographical genetics, accessibility indicators, and may also have applications in other fields of geospatial analysis.

High level functions for hyperplane fitting (hyper.fit()) and visualising (hyper.plot2d() / hyper.plot3d()). In simple terms this allows the user to produce robust 1D linear fits for 2D x vs y type data, and robust 2D plane fits to 3D x vs y vs z type data. This hyperplane fitting works generically for any N-1 hyperplane model being fit to a N dimension dataset. All fits include intrinsic scatter in the generative model orthogonal to the hyperplane.

In order to improve performance for HTTP API clients, httpcache provides simple tools for caching and invalidating cache. It includes the HTTP verb functions GET, PUT, PATCH, POST, and DELETE, which are drop-in replacements for those in the httr package. These functions are cache-aware and provide default settings for cache invalidation suitable for RESTful APIs; the package also enables custom cache-management strategies. Finally, httpcache includes a basic logging framework to facilitate the measurement of HTTP request time and cache performance.

It provides a generic set of tools for initializing a synthetic population with each individual in specific disease states, and making transitions between those disease states according to the rates calculated on each timestep. The new version 1.0.0 has C++ code integration to make the functions run faster. It has also a higher level function to actually run the transitions for the number of timesteps that users specify. Additional functions will follow for changing attributes on demographic, health belief and movement.

This package provides a joint mixture model has been developed by Majumdar et al. (2025) <doi:10.48550/arXiv.2412.17511> that integrates information from gene expression data and methylation data at the modelling stage to capture their inherent dependency structure, enabling simultaneous identification of differentially methylated cytosine-guanine dinucleotide (CpG) sites and differentially expressed genes. The model leverages a joint likelihood function that accounts for the nested structure in the data, with parameter estimation performed using an expectation-maximisation algorithm.

Knowledge space theory by Doignon and Falmagne (1999) <doi:10.1007/978-3-642-58625-5> is a set- and order-theoretical framework, which proposes mathematical formalisms to operationalize knowledge structures in a particular domain. The kstMatrix package provides basic functionalities to generate, handle, and manipulate knowledge structures and knowledge spaces. Opposed to the kst package, kstMatrix uses matrix representations for knowledge structures. Furthermore, kstMatrix contains several knowledge spaces developed by the research group around Cornelia Dowling through querying experts.

Lights Out is a puzzle game consisting of a grid of lights that are either on or off. Pressing any light will toggle it and its adjacent lights. The goal of the game is to switch all the lights off. This package provides an interface to play the game on different board sizes, both through the command line or with a visual application. Puzzles can also be solved using the automatic solver included. View a demo online at <https://daattali.com/shiny/lightsout/>.

Alternate font rendering is useful when rendering text to novel graphics outputs where modern font rendering is not available or where bespoke text positioning is required. Bitmap and vector fonts allow for custom layout and rendering using pixel coordinates and line drawing. Formatted text is created as a data.frame of pixel coordinates (for bitmap fonts) or stroke coordinates (for vector fonts). All text can be easily previewed as a matrix or raster image. A selection of fonts is included with this package.

Fast approximate methods for mixed logistic regression in genome-wide analysis studies (GWAS). Two computationnally efficient methods are proposed for obtaining effect size estimates (beta) in Mixed Logistic Regression in GWAS: the Approximate Maximum Likelihood Estimate (AMLE), and the Offset method. The wald test obtained with AMLE is identical to the score test. Data can be genotype matrices in plink format, or dosage (VCF files). The methods are described in details in Milet et al (2020) <doi:10.1101/2020.01.17.910109>.

This package provides a suite of functions for performing analyses, based on a multiverse approach, for conditioning data. Specifically, given the appropriate data, the functions are able to perform t-tests, analyses of variance, and mixed models for the provided data and return summary statistics and plots. The function is also able to return for all those tests p-values, confidence intervals, and Bayes factors. The methods are described in Lonsdorf, Gerlicher, Klingelhofer-Jens, & Krypotos (2022) <doi:10.1016/j.brat.2022.104072>.

This package provides standardized effect decomposition (direct, indirect, and total effects) for three major structural equation modeling frameworks: lavaan', piecewiseSEM', and plspm'. Automatically handles zero-effect variables, generates publication-ready ggplot2 visualizations, and returns both wide-format and long-format effect tables. Supports effect filtering, multi-model object inputs, and customizable visualization parameters. For a general overview of the methods used in this package, see Rosseel (2012) <doi:10.18637/jss.v048.i02> and Lefcheck (2016) <doi:10.1111/2041-210X.12512>.

Calculate the statistical power to detect clusters using kernel-based spatial relative risk functions that are estimated using the sparr package. Details about the sparr package methods can be found in the tutorial: Davies et al. (2018) <doi:10.1002/sim.7577>. Details about kernel density estimation can be found in J. F. Bithell (1990) <doi:10.1002/sim.4780090616>. More information about relative risk functions using kernel density estimation can be found in J. F. Bithell (1991) <doi:10.1002/sim.4780101112>.

This package provides a URL-safe base64 encoder and decoder. In contrast to RFC3548, the 62nd character (+) is replaced with -, the 63rd character (/) is replaced with _. Furthermore, the encoder does not fill the string with trailing =. The resulting encoded strings comply to the regular expression pattern [A-Za-z0-9_-] and thus are safe to use in URLs or for file names. The package also comes with a simple base32 encoder/decoder suited for case insensitive file systems.

This package implements parametric and non-parametric mediation analysis. This package performs the methods and suggestions in Imai, Keele and Yamamoto (2010) <DOI:10.1214/10-STS321>, Imai, Keele and Tingley (2010) <DOI:10.1037/a0020761>, Imai, Tingley and Yamamoto (2013) <DOI:10.1111/j.1467-985X.2012.01032.x>, Imai and Yamamoto (2013) <DOI:10.1093/pan/mps040> and Yamamoto (2013). In addition to the estimation of causal mediation effects, the software also allows researchers to conduct sensitivity analysis for certain parametric models.

Create beautiful and interactive visualizations in a single function call. The data.table package is utilized to perform the data wrangling necessary to prepare your data for the plot types you wish to build, along with allowing fast processing for big data. There are two broad classes of plots available: standard plots and machine learning evaluation plots. There are lots of parameters available in each plot type function for customizing the plots (such as faceting) and data wrangling (such as variable transformations and aggregation).

Identify and visualize individuals with unusual association patterns of genetics and geography using the approach of Chang and Schmid (2023) <doi:10.1101/2023.04.06.535838>. It detects potential outliers that violate the isolation-by-distance assumption using the K-nearest neighbor approach. You can obtain a table of outliers with statistics and visualize unusual geo-genetic patterns on a geographical map. This is useful for landscape genomics studies to discover individuals with unusual geography and genetics associations from a large biological sample.

This package implements our Bayesian phase I repeated measurement design that accounts for multidimensional toxicity endpoints from multiple treatment cycles. The package also provides a novel design to account for both multidimensional toxicity endpoints and early-stage efficacy endpoints in the phase I design. For both designs, functions are provided to recommend the next dosage selection based on the data collected in the available patient cohorts and to simulate trial characteristics given design parameters. Yin, Jun, et al. (2017) <doi:10.1002/sim.7134>.

Recent years have seen an increased interest in novel methods for analyzing quantitative data from experimental psychology. Currently, however, they lack an established and accessible software framework. Many existing implementations provide no guidelines, consisting of small code snippets, or sets of packages. In addition, the use of existing packages often requires advanced programming experience. PredPsych is a user-friendly toolbox based on machine learning predictive algorithms. It comprises of multiple functionalities for multivariate analyses of quantitative behavioral data based on machine learning models.

Traditional methods for analyzing single cell RNA-seq datasets focus solely on gene expression, but this package introduces a novel approach that goes beyond this limitation. Using Gene Ontology terms as features, the package allows for the functional profile of cell populations, and comparison within and between datasets from the same or different species. Our approach enables the discovery of previously unrecognized functional similarities and differences between cell types and has demonstrated success in identifying cell types functional correspondence even between evolutionarily distant species.

For multiple ranked input lists (full or partial) representing the same set of N objects, the package TopKLists <doi:10.1515/sagmb-2014-0093> offers (1) statistical inference on the lengths of informative top-k lists, (2) stochastic aggregation of full or partial lists, and (3) graphical tools for the statistical exploration of input lists, and for the visualization of aggregation results. Note that RGtk2 and gWidgets2RGtk2 have been archived on CRAN. See <https://github.com/pievos101/TopKLists> for installation instructions.

The Mass Spec Query Language (MassQL) is a domain-specific language enabling to express a query and retrieve mass spectrometry (MS) data in a more natural and understandable way for MS users. It is inspired by SQL and is by design programming language agnostic. The SpectraQL package adds support for the MassQL query language to R, in particular to MS data represented by Spectra objects. Users can thus apply MassQL expressions to analyze and retrieve specific data from Spectra objects.

Testing and documenting code that communicates with remote servers can be painful. This package helps with writing tests for packages that use httr2. It enables testing all of the logic on the R sides of the API without requiring access to the remote service, and it also allows recording real API responses to use as test fixtures. The ability to save responses and load them offline also enables writing vignettes and other dynamic documents that can be distributed without access to a live server.