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Useful functions to analyze proteomic workflows including number of identifications, data completeness, missed cleavages, quantitative and retention time precision etc. Various software outputs are supported such as ProteomeDiscoverer', Spectronaut', DIA-NN and MaxQuant'.
Multivariate estimation and testing, currently a package for testing parametric data. To deal with parametric data, various multivariate normality tests and outlier detection are performed and visualized using the ggplot2 package. Homogeneity tests for covariance matrices are also possible, as well as the Hotelling's T-square test and the multivariate analysis of variance test. We are exploring additional tests and visualization techniques, such as profile analysis and randomized complete block design, to be made available in the future and making them easily accessible to users.
Flexible and informed regression with Multiple Change Points. mcp can infer change points in means, variances, autocorrelation structure, and any combination of these, as well as the parameters of the segments in between. All parameters are estimated with uncertainty and prediction intervals are supported - also near the change points. mcp supports hypothesis testing via Savage-Dickey density ratio, posterior contrasts, and cross-validation. mcp is described in Lindeløv (submitted) <doi:10.31219/osf.io/fzqxv> and generalizes the approach described in Carlin, Gelfand, & Smith (1992) <doi:10.2307/2347570> and Stephens (1994) <doi:10.2307/2986119>.
Automate the explanatory analysis of machine learning predictive models. Generate advanced interactive model explanations in the form of a serverless HTML site with only one line of code. This tool is model-agnostic, therefore compatible with most of the black-box predictive models and frameworks. The main function computes various (instance and model-level) explanations and produces a customisable dashboard, which consists of multiple panels for plots with their short descriptions. It is possible to easily save the dashboard and share it with others. modelStudio facilitates the process of Interactive Explanatory Model Analysis introduced in Baniecki et al. (2023) <doi:10.1007/s10618-023-00924-w>.
Estimation, inference and diagnostics for Univariate Autoregressive Markov Switching Models for Linear and Generalized Models. Distributions for the series include gaussian, Poisson, binomial and gamma cases. The EM algorithm is used for estimation (see Perlin (2012) <doi:10.2139/ssrn.1714016>).
Create tile grid maps, which are like choropleth maps except each region is represented with equal visual space.
Work with Microsoft Access .mdb and .accdb files using the open source MDB Tools library <https://github.com/mdbtools/mdbtools/>. The library is compiled and bundled with the package, so no external installation is required. Provides high-level helpers for reading tables, exporting to CSV or JSON, inspecting table definitions, and running SQL queries. Also exposes a full read-only DBI interface for use with standard database workflows.
This package provides a novel framework to estimate mixed models via gradient boosting. The implemented functions are based on the mboost and lme4 packages, and the family range is therefore determined by lme4'. A correction mechanism for cluster-constant covariates is implemented, as well as estimation of the covariance of random effects. These methods are described in the accompanying publication; see <doi:10.1007/s11222-025-10612-y> for details.
Efficiently estimates single- and multilevel latent class models with covariates, allowing for output visualization in all specifications. For more technical details, see Lyrvall et al. (2025) <doi:10.1080/00273171.2025.2473935>.
This package performs Multiple Factor Analysis method for quantitative, categorical, frequency and mixed data, in addition to generating a lot of graphics, also has other useful functions.
Estimation and inference for multiple kink quantile regression for longitudinal data and the i.i.d data. A bootstrap restarting iterative segmented quantile algorithm is proposed to estimate the multiple kink quantile regression model conditional on a given number of change points. The number of kinks is also allowed to be unknown. In such case, the backward elimination algorithm and the bootstrap restarting iterative segmented quantile algorithm are combined to select the number of change points based on a quantile BIC. For longitudinal data, we also develop the GEE estimator to incorporate the within-subject correlations. A score-type based test statistic is also developed for testing the existence of kink effect. The package is based on the paper, ``Wei Zhong, Chuang Wan and Wenyang Zhang (2022). Estimation and inference for multikink quantile regression, JBES and ``Chuang Wan, Wei Zhong, Wenyang Zhang and Changliang Zou (2022). Multi-kink quantile regression for longitudinal data with application to progesterone data analysis, Biometrics".
Generate multivariate discrete data with generalized Poisson, negative binomial and binomial marginal distributions using user-specified distribution parameters and a target correlation matrix. The method is described in Cheng and Demirtas (2026) <doi:10.48550/arXiv.2602.07707>.
Energy-Vorticity theory (EVT) is the fundamental theory to describe processes in the atmosphere by combining conserved quantities from hydrodynamics and thermodynamics. The package meteoEVT provides functions to calculate many energetic and vortical quantities, like potential vorticity, Bernoulli function and dynamic state index (DSI) [e.g. Weber and Nevir, 2008, <doi:10.1111/j.1600-0870.2007.00272.x>], for given gridded data, like ERA5 reanalyses. These quantities can be studied directly or can be used for many applications in meteorology, e.g., the objective identification of atmospheric fronts. For this purpose, separate function are provided that allow the detection of fronts based on the thermic front parameter [Hewson, 1998, <doi:10.1017/S1350482798000553>], the F diagnostic [Parfitt et al., 2017, <doi:10.1002/2017GL073662>] and the DSI [Mack et al., 2022, <arXiv:2208.11438>].
Constructing matrices for quick prototyping can be a nuisance, requiring the user to think about how to fill the matrix with values using the matrix() function. The %<-% operator solves that issue by allowing the user to construct matrices using code that shows the actual matrices.
The time series forecasting framework for use with the tidymodels ecosystem. Models include ARIMA, Exponential Smoothing, and additional time series models from the forecast and prophet packages. Refer to "Forecasting Principles & Practice, Second edition" (<https://otexts.com/fpp2/>). Refer to "Prophet: forecasting at scale" (<https://research.facebook.com/blog/2017/02/prophet-forecasting-at-scale/>.).
This package provides mailmerge methods for reading spreadsheets of addresses and other relevant information to create standardized but customizable letters. Provides a method for mapping US ZIP codes, including those of letter recipients. Provides a method for parsing and processing html code from online job postings of the American Political Science Association.
Given a set of models for which a measure of model (mis)fit and model complexity is provided, CHull(), developed by Ceulemans and Kiers (2006) <doi:10.1348/000711005X64817>, determines the models that are located on the boundary of the convex hull and selects an optimal model by means of the scree test values.
It can be used to create/encode molecular "license-plates" from sequences and to also decode the "license-plates" back to sequences. While initially created for transfer RNA-derived small fragments (tRFs), this tool can be used for any genomic sequences including but not limited to: tRFs, microRNAs, etc. The detailed information can reference to Pliatsika V, Loher P, Telonis AG, Rigoutsos I (2016) <doi:10.1093/bioinformatics/btw194>. It can also be used to annotate tRFs. The detailed information can reference to Loher P, Telonis AG, Rigoutsos I (2017) <doi:10.1038/srep41184>.
This package provides a custom imputation method for the mice package based on distributional random forests. The package implements the mice.impute.DRF method, which can be used within the standard mice workflow. Missing values are imputed by estimating conditional distributions with distributional random forests and sampling observed responses using forest weights.
This package provides functions for fitting monotone polynomials to data. Detailed discussion of the methodologies used can be found in Murray, Mueller and Turlach (2013) <doi:10.1007/s00180-012-0390-5> and Murray, Mueller and Turlach (2016) <doi:10.1080/00949655.2016.1139582>.
Flexible time classes for time series analysis and forecasting with mixed temporal granularities. Supports linear and cyclical time representations in discrete and continuous forms, with timezone support, across multiple calendar systems including Gregorian and ISO week date calendars. Time points are stored numerically relative to a chronon; an atomic time granule defined by time units of a calendar. Calendrical arithmetic enables conversion between time granules (e.g. days to months) and calendar systems. Multi-unit arithmetic allows for temporal analysis with other granules of common calendars (e.g. fortnights are 2-week units). Time vectors of different granularities (e.g. monthly and quarterly) can be combined in a single vector, making mixtime ideal for data that changes observation frequency over time or requires temporal reconciliation across scales. The package is extensible, allowing users to define custom calendars that build upon civil and astronomical time systems.
To perform main effect matrix factor model (MEFM) estimation for a given matrix time series as described in Lam and Cen (2024) <doi:10.48550/arXiv.2406.00128>. Estimation of traditional matrix factor models is also supported. Supplementary functions for testing MEFM over factor models are included.
This package performs Modal Clustering (MAC) including Hierarchical Modal Clustering (HMAC) along with their parallel implementation (PHMAC) over several processors. These model-based non-parametric clustering techniques can extract clusters in very high dimensions with arbitrary density shapes. By default clustering is performed over several resolutions and the results are summarised as a hierarchical tree. Associated plot functions are also provided. There is a package vignette that provides many examples. This version adheres to CRAN policy of not spanning more than two child processes by default.
An interactive document on the topic of multidimensional scaling and principal component analysis using rmarkdown and shiny packages. Runtime examples are provided in the package function as well as at <https://kartikeyabolar.shinyapps.io/MDS_PCAShiny/>.