This is a shape preserving spline <doi:10.1137/0720057> which is guaranteed to be monotonic and concave or convex if the data is monotonic and concave or convex. It does not use any optimisation and is therefore quick and smoothly converges to a fixed point in economic dynamics problems including value function iteration. It also automatically gives the first two derivatives of the spline and options for determining behaviour when evaluated outside the interpolation domain.

Wavelet decomposes a series into multiple sub series called detailed and smooth components which helps to capture volatility at multi resolution level by various models. Two hybrid Machine Learning (ML) models (Artificial Neural Network and Support Vector Regression have been used) have been developed in combination with stochastic models, feature selection, and optimization algorithms for prediction of the data. The algorithms have been developed following Paul and Garai (2021) <doi:10.1007/s00500-021-06087-4>.

This package provides tools for working with rotational data, including simulation from the most commonly used distributions on SO(3), methods for different Bayes, mean and median type estimators for the central orientation of a sample, confidence/credible regions for the central orientation based on those estimators and a novel visualization technique for rotation data. Most recently, functions to identify potentially discordant (outlying) values have been added. References: Bingham, Melissa A. and Nordman, Dan J. and Vardeman, Steve B. (2009), Bingham, Melissa A and Vardeman, Stephen B and Nordman, Daniel J (2009), Bingham, Melissa A and Nordman, Daniel J and Vardeman, Stephen B (2010), Leon, C.A. and Masse, J.C. and Rivest, L.P. (2006), Hartley, R and Aftab, K and Trumpf, J. (2011), Stanfill, Bryan and Genschel, Ulrike and Hofmann, Heike (2013), Maonton, Jonathan (2004), Mardia, KV and Jupp, PE (2000, ISBN:9780471953333), Rancourt, D. and Rivest, L.P. and Asselin, J. (2000), Chang, Ted and Rivest, Louis-Paul (2001), Fisher, Nicholas I. (1996, ISBN:0521568900).

This package contains simple routines for finding roots, or zeros, of scalar functions of a single real variable using floating-point math. The find_zero function provides the primary interface. The basic call is find_zero(f, x0, [M], [p]; kws...) where, typically, f is a function, x0 a starting point or bracketing interval, M is used to adjust the default algorithms used, and p can be used to pass in parameters.

This package provides functions for animations in statistics, covering topics in probability theory, mathematical statistics, multivariate statistics, non-parametric statistics, sampling survey, linear models, time series, computational statistics, data mining and machine learning. These functions may be helpful in teaching statistics and data analysis. Also provided in this package are a series of functions to save animations to various formats, e.g. GIF, HTML pages, PDF, and videos. PDF animations can be inserted into Sweave / knitr easily.

This package aims to integrate GWAS-derived SNPs and coexpression networks to mine candidate genes associated with a particular phenotype. For that, users must define a set of guide genes, which are known genes involved in the studied phenotype. Additionally, the mined candidates can be given a score that favor candidates that are hubs and/or transcription factors. The scores can then be used to rank and select the top n most promising genes for downstream experiments.

The mixed model for repeated measures (MMRM) is a popular model for longitudinal clinical trial data with continuous endpoints, and brms is a powerful and versatile package for fitting Bayesian regression models. The brms.mmrm R package leverages brms to run MMRMs, and it supports a simplified interfaced to reduce difficulty and align with the best practices of the life sciences. References: Bürkner (2017) <doi:10.18637/jss.v080.i01>, Mallinckrodt (2008) <doi:10.1177/009286150804200402>.

This package provides a data package with 2 main package variables: signature and etiology'. The signature variable contains the latest mutational signature profiles released on COSMIC <https://cancer.sanger.ac.uk/signatures/> for 3 mutation types: * Single base substitutions in the context of preceding and following bases, * Doublet base substitutions, and * Small insertions and deletions. The etiology variable provides the known or hypothesized causes of signatures. cosmicsig stands for COSMIC signatures. Please run ?'cosmicsig for more information.

Calculate with spectral properties of light sources, materials, cameras, eyes, and scanners. Build complex systems from simpler parts using a spectral product algebra. For light sources, compute CCT, CRI, SSI, and IES TM-30 reports. For object colors, compute optimal colors and Logvinenko coordinates. Work with the standard CIE illuminants and color matching functions, and read spectra from text files, including CGATS files. Estimate a spectrum from its response. A user guide and 9 vignettes are included.

In clinical practice and research settings in medicine and the behavioral sciences, it is often of interest to quantify the correlation of a continuous endpoint that was repeatedly measured (e.g., test-retest correlations, ICC, etc.). This package allows for estimating these correlations based on mixed-effects models. Part of this software has been developed using funding provided from the European Union's 7th Framework Programme for research, technological development and demonstration under Grant Agreement no 602552.

This package provides a systematic biology tool was developed to repurpose drugs via a subpathway crosstalk network. The operation modes include 1) calculating centrality scores of SPs in the context of gene expression data to reflect the influence of SP crosstalk, 2) evaluating drug-disease reverse association based on disease- and drug-induced SPs weighted by the SP crosstalk, 3) identifying cancer candidate drugs through perturbation analysis. There are also several functions used to visualize the results.

This package provides a comprehensive collection of utility functions for data analysis and visualization in R. The package provides 60+ functions for data manipulation, file handling, color palette management, bioinformatics workflows, statistical analysis, plotting, and package management. Features include void value handling, custom infix operators, flexible file I/O, and publication-ready visualizations with sensible defaults. Implementation follows tidyverse principles (Wickham et al. (2019) <doi:10.21105/joss.01686>) and incorporates best practices from the R community.

This package provides routines to estimate the Mixture Transition Distribution Model based on Raftery (1985) <http://www.jstor.org/stable/2345788> and Nicolau (2014) <doi:10.1111/sjos.12087> specifications, for multivariate data. Additionally, provides a function for the estimation of a new model for multivariate non-homogeneous Markov chains. This new specification, Generalized Multivariate Markov Chains (GMMC) was proposed by Carolina Vasconcelos and Bruno Damasio and considers (continuous or discrete) covariates exogenous to the Markov chain.

This package provides a collection of gold price data in various currencies in the form of USD, EUR, JPY, GBP, CAD, CHF, INR, CNY, TRY, SAR, IDR, AED, THB, VND, EGP, KRW, RUB, ZAR, and AUD. This data comes from the World Gold Council. In addition, the data is in the form of daily, weekly, monthly (average and the end of period), quarterly (average and the end of period), and yearly (average and the end of period).

This package implements key features of Gephi for network visualization, including ForceAtlas2 (with LinLog mode), network scaling, and network rotations. It also includes easy network visualization tools such as edge and node color assignment for recreating Gephi'-style graphs in R. The package references layout algorithms developed by Jacomy, M., Venturini T., Heymann S., and Bastian M. (2014) <doi:10.1371/journal.pone.0098679> and Noack, A. (2009) <doi:10.48550/arXiv.0807.4052>.

This package implements maximum likelihood estimation for Gaussian processes, supporting both isotropic and separable models with predictive capabilities. Includes penalized likelihood estimation following Li and Sudjianto (2005, <doi:10.1198/004017004000000671>), with cross-validation guided by decorrelated prediction error (DPE) metric. DPE metric, motivated by Mahalanobis distance, serves as evaluation criteria that accounts for predictive uncertainty in tuning parameter selection (Mutoh, Booth, and Stallrich, 2025, <doi:10.48550/arXiv.2511.18111>). Designed specifically for small datasets.

Graphical visualization tools for analyzing the data produced by irace'. The iraceplot package enables users to analyze the performance and the parameter space data sampled by the configuration during the search process. It provides a set of functions that generate different plots to visualize the configurations sampled during the execution of irace and their performance. The functions just require the log file generated by irace and, in some cases, they can be used with user-provided data.

An implementation of the correction methods proposed by Shu and Yi (2017) <doi:10.1177/0962280217743777> for the inverse probability weighted (IPW) estimation of average treatment effect (ATE) with misclassified binary outcomes. Logistic regression model is assumed for treatment model for all implemented correction methods, and is assumed for the outcome model for the implemented doubly robust correction method. Misclassification probability given a true value of the outcome is assumed to be the same for all individuals.

Estimate the mean of a Gaussian vector, by choosing among a large collection of estimators, following the method developed by Y. Baraud, C. Giraud and S. Huet (2014) <doi:10.1214/13-AIHP539>. In particular it solves the problem of variable selection by choosing the best predictor among predictors emanating from different methods as lasso, elastic-net, adaptive lasso, pls, randomForest. Moreover, it can be applied for choosing the tuning parameter in a Gauss-lasso procedure.

This package provides tools for training, selecting, and evaluating maximum entropy (and standard logistic regression) distribution models. This package provides tools for user-controlled transformation of explanatory variables, selection of variables by nested model comparison, and flexible model evaluation and projection. It follows principles based on the maximum- likelihood interpretation of maximum entropy modeling, and uses infinitely- weighted logistic regression for model fitting. The package is described in Vollering et al. (2019; <doi:10.1002/ece3.5654>).

Perform a mail merge (mass email) using the message defined in markdown, the recipients in a csv file, and gmail as the mailing engine. With this package you can parse markdown documents as the body of email, and the yaml header to specify the subject line of the email. Any braces in the email will be encoded with glue::glue()'. You can preview the email in the RStudio viewer pane, and send (draft) email using gmailr'.

This package provides a simple R interface to the OPUS Miner algorithm (implemented in C++) for finding the top-k productive, non-redundant itemsets from transaction data. The OPUS Miner algorithm uses the OPUS search algorithm to efficiently discover the key associations in transaction data, in the form of self-sufficient itemsets, using either leverage or lift. See <http://i.giwebb.com/index.php/research/association-discovery/> for more information in relation to the OPUS Miner algorithm.

Simplifies the manufacturing, analysis and display of pressure volume and leaf drying curves. From the progression of the curves turgor loss point, osmotic potential, apoplastic fraction as well as minimum conductance and stomatal closure can be derived. Methods adapted from Bartlett, Scoffoni, Sack (2012) <doi:10.1111/j.1461-0248.2012.01751.x> and Sack, Scoffoni, PrometheusWikiContributors (2011) <http://prometheuswiki.org/tiki-index.php?page=Minimum+epidermal+conductance+%28gmin%2C+a.k.a.+cuticular+conductance%29>.

Topological data analysis is a powerful tool for finding non-linear global structure in whole datasets. The main tool of topological data analysis is persistent homology, which computes a topological shape descriptor of a dataset called a persistence diagram. TDApplied provides useful and efficient methods for analyzing groups of persistence diagrams with machine learning and statistical inference, and these functions can also interface with other data science packages to form flexible and integrated topological data analysis pipelines.