Confidence intervals and point estimation for R under various parametric model assumptions; likelihood inference based on classical first-order approximations and higher-order asymptotic procedures.

Fast and Accurate Randomized Singular Value Decomposition (RSVD) methods proposed in the PCAone paper by Li (2023) <https://genome.cshlp.org/content/33/9/1599>.

Utility functions for the handling, analysis and visualisation of data from portable emissions measurement systems ('PEMS') and other similar mobile activity monitoring devices. The package includes a dedicated pems data class that manages many of the quality control, unit handling and data archiving issues that can hinder efforts to standardise PEMS research.

This package implements a Bayesian profile regression using a generalized linear mixed model as output model. The package allows for binary (probit mixed model) and continuous (linear mixed model) outcomes and both continuous and categorical clustering variables. The package utilizes RcppArmadillo and RcppDist for high-performance statistical computing in C++. For more details see Amestoy & al. (2025) <doi:10.48550/arXiv.2510.08304>.

Displays provenance graphically for provenance collected by the rdt or rdtLite packages, or other tools providing compatible PROV JSON output. The exact format of the JSON created by rdt and rdtLite is described in <https://github.com/End-to-end-provenance/ExtendedProvJson>. More information about rdtLite and associated tools is available at <https://github.com/End-to-end-provenance/> and Barbara Lerner, Emery Boose, and Luis Perez (2018), Using Introspection to Collect Provenance in R, Informatics, <doi: 10.3390/informatics5010012>.

An API wrapper around the ProPublica API <https://projects.propublica.org/api-docs/congress-api/> for U.S. Congressional Bills. Users can include their API key, U.S. Congress, branch, and offset ranges, to return a dataframe of all results within those parameters. This package is different from the RPublica package because it is for the ProPublica U.S. Congress data API, and the RPublica package is for the Nonprofit Explorer, Forensics, and Free the Files data APIs.

Text mining of PubMed Abstracts (text and XML) from <https://pubmed.ncbi.nlm.nih.gov/>.

Analysis of terms in linear, generalized and mixed linear models, on the basis of multiple comparisons of factor contrasts. Specially suited for the analysis of interaction terms.

This package provides tools for transforming, a posteriori time-scaling, and modifying phylogenies containing extinct (i.e. fossil) lineages. In particular, most users are interested in the functions timePaleoPhy, bin_timePaleoPhy, cal3TimePaleoPhy and bin_cal3TimePaleoPhy, which date cladograms of fossil taxa using stratigraphic data. This package also contains a large number of likelihood functions for estimating sampling and diversification rates from different types of data available from the fossil record (e.g. range data, occurrence data, etc). paleotree users can also simulate diversification and sampling in the fossil record using the function simFossilRecord, which is a detailed simulator for branching birth-death-sampling processes composed of discrete taxonomic units arranged in ancestor-descendant relationships. Users can use simFossilRecord to simulate diversification in incompletely sampled fossil records, under various models of morphological differentiation (i.e. the various patterns by which morphotaxa originate from one another), and with time-dependent, longevity-dependent and/or diversity-dependent rates of diversification, extinction and sampling. Additional functions allow users to translate simulated ancestor-descendant data from simFossilRecord into standard time-scaled phylogenies or unscaled cladograms that reflect the relationships among taxon units.

This is a data only package, that provides distances from a paper plane experiment.

This is an implementation of model-based trees with global model parameters (PALM trees). The PALM tree algorithm is an extension to the MOB algorithm (implemented in the partykit package), where some parameters are fixed across all groups. Details about the method can be found in Seibold, Hothorn, Zeileis (2016) <arXiv:1612.07498>. The package offers coef(), logLik(), plot(), and predict() functions for PALM trees.

This package provides a framework for building enterprise, scalable and UI-standardized shiny applications. It brings enhanced features such as bootstrap v4 <https://getbootstrap.com/docs/4.0/getting-started/introduction/>, additional and enhanced shiny modules, customizable UI features, as well as an enhanced application file organization paradigm. This update allows developers to harness the ability to build powerful applications and enriches the shiny developers experience when building and maintaining applications.

Producing the time-dependent receiver operating characteristic (ROC) curve through parametric approaches. Tools for generating random data, fitting, predicting and check goodness of fit are prepared. The methods are developed from the theoretical framework of proportional hazard model and copula functions. Using this package, users can now simulate parametric time-dependent ROC and run experiment to understand the behavior of the curve under different scenario.

PROMETHEE (Preference Ranking Organisation METHod for Enrichment of Evaluations) based method assesses alternatives to obtain partial and complete rankings. The package also provides the GLNF (Global Local Net Flow) sorting algorithm to classify alternatives into ordered categories, as well as an index function to measure the classification quality. Barrera, F., Segura, M., & Maroto, C. (2023) <doi:10.1111/itor.13288>. Brans, J.P.; De Smet, Y., (2016) <doi:10.1007/978-1-4939-3094-4_6>.

Set of functions that implement the PoDBAY method, described in the publication A method to estimate probability of disease and vaccine efficacy from clinical trial immunogenicity data by Julie Dudasova, Regina Laube, Chandni Valiathan, Matthew C. Wiener, Ferdous Gheyas, Pavel Fiser, Justina Ivanauskaite, Frank Liu and Jeffrey R. Sachs (NPJ Vaccines, 2021), <doi:10.1038/s41541-021-00377-6>.

This package performs minimax linkage hierarchical clustering. Every cluster has an associated prototype element that represents that cluster as described in Bien, J., and Tibshirani, R. (2011), "Hierarchical Clustering with Prototypes via Minimax Linkage," The Journal of the American Statistical Association, 106(495), 1075-1084.

Can be used to carry out permutation based gene expression pathway analysis. This work was supported by a National Institute of Allergy and Infectious Disease/National Institutes of Health contract (No. HHSN272200900059C).

This takes in a series of multi-layer raster files and returns a phenology projection raster, following methodologies described in John (2016) <https://etda.libraries.psu.edu/catalog/13521clj5135>.

Leading/lagging a panel, creating dummy variables, taking panel differences, looking for panel autocorrelations, and more. Implemented via a data.table back end.

This package provides a unified framework for generating, submitting, and analyzing pairwise comparisons of writing quality using large language models (LLMs). The package supports live and/or batch evaluation workflows across multiple providers ('OpenAI', Anthropic', Google Gemini', Together AI', and locally-hosted Ollama models), includes bias-tested prompt templates and a flexible template registry, and offers tools for constructing forward and reversed comparison sets to analyze consistency and positional bias. Results can be modeled using Bradleyâ Terry (1952) <doi:10.2307/2334029> or Elo rating methods to derive writing quality scores. For information on the method of pairwise comparisons, see Thurstone (1927) <doi:10.1037/h0070288> and Heldsinger & Humphry (2010) <doi:10.1007/BF03216919>. For information on Elo ratings, see Clark et al. (2018) <doi:10.1371/journal.pone.0190393>.

All PubChem compounds are downloaded to a local computer, but for each compound, only partial records are used. The data are organized into small files referenced by PubChem CID. This package also contains functions to parse the biologically relevant compounds from all PubChem compounds, using biological database sources, pathway presence, and taxonomic relationships. Taxonomy is used to generate a lowest common ancestor taxonomy ID (NCBI) for each biological metabolite, which then enables creation of taxonomically specific metabolome databases for any taxon.

This package provides a simple interface for extracting various elements from the publicly available PubMed XML files, incorporating PubMed's regular updates, and combining the data with the NIH Open Citation Collection. See Schoenbachler and Hughey (2021) <doi:10.7717/peerj.11071>.

Portfolio optimization and analysis routines and graphics.

This package provides a suite of empirical Bayes methods to use in pharmacovigilance. Contains various model fitting and post-processing functions. For more details see Tan et al. (2025) <doi:10.48550/arXiv.2502.09816>, <doi:10.48550/arXiv.2512.01057>; Koenker and Mizera (2014) <doi:10.1080/01621459.2013.869224>; Efron (2016) <doi:10.1093/biomet/asv068>.