This package implements the "shrinkage t" statistic introduced in Opgen-Rhein and Strimmer (2007) <DOI:10.2202/1544-6115.1252> and a shrinkage estimate of the "correlation-adjusted t-score" (CAT score) described in Zuber and Strimmer (2009) <DOI:10.1093/bioinformatics/btp460>. It also offers a convenient interface to a number of other regularized t-statistics commonly employed in high-dimensional case-control studies.

This package provides functions to estimate the insertion and deletion rates of transposable element (TE) families. The estimation of insertion rate consists of an improved estimate of the age distribution that takes into account random mutations, and an adjustment by the deletion rate. A hypothesis test for a uniform insertion rate is also implemented. This package implements the methods proposed in Dai et al (2018).

An enhanced implementation of Whittaker-Henderson smoothing for the graduation of one-dimensional and two-dimensional actuarial tables used to quantify Life Insurance risks. WH is based on the methods described in Biessy (2025) <doi:10.48550/arXiv.2306.06932>. Among other features, it generalizes the original smoothing algorithm to maximum likelihood estimation, automatically selects the smoothing parameter(s) and extrapolates beyond the range of data.

The computation of quadratic form (QF) distributions is often not trivial and it requires numerical routines. The package contains functions aimed at evaluating the exact distribution of quadratic forms (QFs) and ratios of QFs. In particular, we propose to evaluate density, quantile and distribution functions of positive definite QFs and ratio of independent positive QFs by means of an algorithm based on the numerical inversion of Mellin transforms.

re2c generates minimalistic hard-coded state machine (as opposed to full-featured table-based lexers). A flexible API allows generated code to be wired into virtually any environment. Instead of exposing a traditional yylex() style API, re2c exposes its internals. Be sure to take a look at the examples, as they cover a lot of real-world cases and shed some light on dark corners of the re2c API.

Empirical likelihood (EL) inference for two-sample problems. The following statistics are included: the difference of two-sample means, smooth Huber estimators, quantile (qdiff) and cumulative distribution functions (ddiff), probability-probability (P-P) and quantile-quantile (Q-Q) plots as well as receiver operating characteristic (ROC) curves. EL calculations are based on J. Valeinis, E. Cers (2011) <http://home.lu.lv/~valeinis/lv/petnieciba/EL_TwoSample_2011.pdf>.

This package provides a minimal R and C++ API for parsing well-known binary and well-known text representation of geometries to and from R-native formats. Well-known binary is compact and fast to parse; well-known text is human-readable and is useful for writing tests. These formats are only useful in R if the information they contain can be accessed in R, for which high-performance functions are provided here.

Comprehensive data analysis software, and the name "cg" stands for "compare groups." Its genesis and evolution are driven by common needs to compare administrations, conditions, etc. in medicine research and development. The current version provides comparisons of unpaired samples, i.e. a linear model with one factor of at least two levels. It also provides comparisons of two paired samples. Good data graphs, modern statistical methods, and useful displays of results are emphasized.

Defines S3 vector data types for vectors of functional data (grid-based, spline-based or functional principal components-based) with all arithmetic and summary methods, derivation, integration and smoothing, plotting, data import and export, and data wrangling, such as re-evaluating, subsetting, sub-assigning, zooming into sub-domains, or extracting functional features like minima/maxima and their locations. The implementation allows including such vectors in data frames for joint analysis of functional and scalar variables.

RSEM is a software package for estimating gene and isoform expression levels from RNA-Seq data. The RSEM package provides a user-friendly interface, supports threads for parallel computation of the EM algorithm, single-end and paired-end read data, quality scores, variable-length reads and RSPD estimation. In addition, it provides posterior mean and 95% credibility interval estimates for expression levels. For visualization, it can generate BAM and Wiggle files in both transcript-coordinate and genomic-coordinate.

Build display tables from tabular data with an easy-to-use set of functions. With its progressive approach, we can construct display tables with a cohesive set of table parts. Table values can be formatted using any of the included formatting functions. Footnotes and cell styles can be precisely added through a location targeting system. The way in which gt handles things for you means that you don't often have to worry about the fine details.

Estimates the attributable fraction in different sampling designs adjusted for measured confounders using logistic regression (cross-sectional and case-control designs), conditional logistic regression (matched case-control design), Cox proportional hazard regression (cohort design with time-to- event outcome), gamma-frailty model with a Weibull baseline hazard and instrumental variables analysis. An exploration of the AF with a genetic exposure can be found in the package AFheritability Dahlqwist E et al. (2019) <doi:10.1007/s00439-019-02006-8>.

This package provides functions to estimate the parameters of the generalized Poisson distribution with or without covariates using maximum likelihood. The references include Nikoloulopoulos A.K. & Karlis D. (2008). "On modeling count data: a comparison of some well-known discrete distributions". Journal of Statistical Computation and Simulation, 78(3): 437--457, <doi:10.1080/10629360601010760> and Consul P.C. & Famoye F. (1992). "Generalized Poisson regression model". Communications in Statistics - Theory and Methods, 21(1): 89--109, <doi:10.1080/03610929208830766>.

This package provides a "tabular-data-resource" (<https://specs.frictionlessdata.io/tabular-data-resource/>) is a simple format to describe a singular tabular data resource such as a CSV file. It includes support both for metadata such as author and title and a schema to describe the data, for example the types of the fields/columns in the data. Create a tabular-data-resource by providing a data.frame and specifying metadata. Write and read tabular-data-resources to and from disk.

The PP package includes estimation of (MLE, WLE, MAP, EAP, ROBUST) person parameters for the 1,2,3,4-PL model and the GPCM (generalized partial credit model). The parameters are estimated under the assumption that the item parameters are known and fixed. The package is useful e.g. in the case that items from an item pool / item bank with known item parameters are administered to a new population of test-takers and an ability estimation for every test-taker is needed.

Finds causal connections in precision data, finds lags and embeddings in time series, guides training of neural networks and other smooth models, evaluates their performance, gives a mathematically grounded answer to the over-training problem. Smooth regression is based on the Gamma test, which measures smoothness in a multivariate relationship. Causal relations are smooth, noise is not. sr includes the Gamma test and search techniques that use it. References: Evans & Jones (2002) <doi:10.1098/rspa.2002.1010>, AJ Jones (2004) <doi:10.1007/s10287-003-0006-1>.

Functions, methods, and datasets for fitting dimension reduction regression, using slicing (methods SAVE and SIR), Principal Hessian Directions (phd, using residuals and the response), and an iterative IRE. Partial methods, that condition on categorical predictors are also available. A variety of tests, and stepwise deletion of predictors, is also included. Also included is code for computing permutation tests of dimension. Adding additional methods of estimating dimension is straightforward. For documentation, see the vignette in the package. With version 3.0.4, the arguments for dr.step have been modified.

In Australia, a financial year (or fiscal year) is the period from 1 July to 30 June of the following calendar year. As such, many databases need to represent and validate financial years efficiently. While the use of integer years with a convention that they represent the year ending is common, it may lead to ambiguity with calendar years. On the other hand, string representations may be too inefficient and do not easily admit arithmetic operations. This package tries to make validation of financial years quicker while retaining clarity.

An implementation of the MaxLFQ algorithm by Cox et al. (2014) <doi:10.1074/mcp.M113.031591> in a comprehensive pipeline for processing proteomics data in data-independent acquisition mode (Pham et al. 2020 <doi:10.1093/bioinformatics/btz961>). It offers additional options for protein quantification using the N most intense fragment ions, using all fragment ions, the median polish algorithm by Tukey (1977, ISBN:0201076160), and a robust linear model. In general, the tool can be used to integrate multiple proportional observations into a single quantitative value.

This package implements functions to derive uncertainty intervals for (i) regression (linear and probit) parameters when outcome is missing not at random (non-ignorable missingness) introduced in Genbaeck, M., Stanghellini, E., de Luna, X. (2015) <doi:10.1007/s00362-014-0610-x> and Genbaeck, M., Ng, N., Stanghellini, E., de Luna, X. (2018) <doi:10.1007/s10433-017-0448-x>; and (ii) double robust and outcome regression estimators of average causal effects (on the treated) with possibly unobserved confounding introduced in Genbaeck, M., de Luna, X. (2018) <doi:10.1111/biom.13001>.

The quantity-intensity (Q/I) relationships, first introduced by Beckett (1964), can be employed to assess the K supplying capacity of different soils based on solid-solution exchange equilibria. Such relationships describe the changes in K+ concentration in the soil solution (or the intensity factor) in relation to the corresponding changes in K+ at exchange sites of the soil (or the capacity or quantity factor). Activity ratio of K to Ca or Ca+Mg is generally used as the variable denoting the intensity, whereas, change in exchangeable K is used to denote the quantity factor.

RCCL (pronounced "Rickle") is a stand-alone library of standard collective communication routines for GPUs, implementing all-reduce, all-gather, reduce, broadcast, reduce-scatter, gather, scatter, and all-to-all. There is also initial support for direct GPU-to-GPU send and receive operations. It has been optimized to achieve high bandwidth on platforms using PCIe, xGMI as well as networking using InfiniBand Verbs or TCP/IP sockets. RCCL supports an arbitrary number of GPUs installed in a single node or multiple nodes, and can be used in either single- or multi-process (e.g., MPI) applications.

Discriminant Analysis (DA) for evolutionary inference (Qin, X. et al, 2020, <doi:10.22541/au.159256808.83862168>), especially for population genetic structure and community structure inference. This package incorporates the commonly used linear and non-linear, local and global supervised learning approaches (discriminant analysis), including Linear Discriminant Analysis of Kernel Principal Components (LDAKPC), Local (Fisher) Linear Discriminant Analysis (LFDA), Local (Fisher) Discriminant Analysis of Kernel Principal Components (LFDAKPC) and Kernel Local (Fisher) Discriminant Analysis (KLFDA). These discriminant analyses can be used to do ecological and evolutionary inference, including demography inference, species identification, and population/community structure inference.

Cross-validation methods of regression models that exploit features of various modeling functions to improve speed. Some of the methods implemented in the package are novel, as described in the package vignettes; for general introductions to cross-validation, see, for example, Gareth James, Daniela Witten, Trevor Hastie, and Robert Tibshirani (2021, ISBN 978-1-0716-1417-4, Secs. 5.1, 5.3), "An Introduction to Statistical Learning with Applications in R, Second Edition", and Trevor Hastie, Robert Tibshirani, and Jerome Friedman (2009, ISBN 978-0-387-84857-0, Sec. 7.10), "The Elements of Statistical Learning, Second Edition".