survClust is an outcome weighted integrative clustering algorithm used to classify multi-omic samples on their available time to event information. The resulting clusters are cross-validated to avoid over overfitting and output classification of samples that are molecularly distinct and clinically meaningful. It takes in binary (mutation) as well as continuous data (other omic types).

ChemmineR is a cheminformatics package for analyzing drug-like small molecule data in R. It contains functions for efficient processing of large numbers of molecules, physicochemical/structural property predictions, structural similarity searching, classification and clustering of compound libraries with a wide spectrum of algorithms. In addition, it offers visualization functions for compound clustering results and chemical structures.

TFBSTools is a package for the analysis and manipulation of transcription factor binding sites. It includes matrices conversion between Position Frequency Matrix (PFM), Position Weight Matrix (PWM) and Information Content Matrix (ICM). It can also scan putative TFBS from sequence/alignment, query JASPAR database and provides a wrapper of de novo motif discovery software.

The wordspace package turns R into an interactive laboratory for empirical research on distributional semantic models (DSM). It consists of a small set of carefully designed functions, most of which

• encapsulate non-trivial R operations in a user-friendly manner or

• provide efficient and memory-lean C implementations of key operations.

Rudel is a collaborative editing environment for GNU Emacs. Its purpose is to share buffers with other users in order to edit the contents of those buffers collaboratively. Rudel supports multiple backends to enable communication with other collaborative editors using different protocols, though currently Obby (for use with the Gobby editor) is the only fully-functional one.

This package provides a method for modeling genetic data as a combination of discrete layers, within each of which relatedness may decay continuously with geographic distance. This package contains code for running analyses (which are implemented in the modeling language rstan') and visualizing and interpreting output. See the paper for more details on the model and its utility.

Quality control and formatting tools developed for the Copernicus Data Rescue Service. The package includes functions to handle the Station Exchange Format (SEF), various statistical tests for climate data at daily and sub-daily resolution, as well as functions to plot the data. For more information and documentation see <https://datarescue.climate.copernicus.eu/st_data-quality-control>.

This package implements an estimation method for Hawkes processes when count data are only observed in discrete time, using a spectral approach derived from the Bartlett spectrum, see Cheysson and Lang (2020) <arXiv:2003.04314>. Some general use functions for Hawkes processes are also included: simulation of (in)homogeneous Hawkes process, maximum likelihood estimation, residual analysis, etc.

Generates Hadamard matrices using different construction methods. For those who want to generate Hadamard matrix, a generic function, Hadamard_matrix() is provided. For those who want to generate Hadamard matrix using a particular method, separate functions are available. See Horadam (2007, ISBN:9780691119212) Hadamard Matrices and their applications, Princeton University Press for more information on Hadamard Matrices.

Includes support for Mapbox Navigation APIs, including directions, isochrones, and route optimization; the Search API for forward and reverse geocoding; the Maps API for interacting with Mapbox vector tilesets and visualizing Mapbox maps in R; and Mapbox Tiling Service and tippecanoe for generating map tiles. See <https://docs.mapbox.com/api/> for more information about the Mapbox APIs.

This package provides a lightweight package designed to facilitate statistical simulations through functional programming. It centralizes the simulation process into a single higher-order function, enhancing manageability and usability without adding overhead from external dependencies. The package includes ready-to-use functions for common simulation targets. A detailed example can be found on <https://github.com/ielbadisy/mcstatsim>.

Dataset and functions from the meta-analysis published in Medicine & Science in Sports & Exercise. It contains all the data and functions to reproduce the analysis. "Effectiveness of HIIE versus MICT in Improving Cardiometabolic Risk Factors in Health and Disease: A Meta-analysis". Felipe Mattioni Maturana, Peter Martus, Stephan Zipfel, Andreas M Nieà (2020) <doi:10.1249/MSS.0000000000002506>.

This package provides a set of commands to manage an abstract optimization method. The goal is to provide a building block for a large class of specialized optimization methods. This package manages: the number of variables, the minimum and maximum bounds, the number of non linear inequality constraints, the cost function, the logging system, various termination criteria, etc...

This package implements novel tools for estimating sample sizes needed for phylogenetic studies, including studies focused on estimating the probability of true pathogen transmission between two cases given phylogenetic linkage and studies focused on tracking pathogen variants at a population level. Methods described in Wohl, Giles, and Lessler (2021) and in Wohl, Lee, DiPrete, and Lessler (2023).

Fast computation of the required sample size or the achieved power, for GWAS studies with different types of covariate effects and different types of covariate-gene dependency structure. For the detailed description of the methodology, see Zhang (2022) "Power and Sample Size Computation for Genetic Association Studies of Binary Traits: Accounting for Covariate Effects" <arXiv:2203.15641>.

This package provides functions for converting among CIE XYZ, xyY, Lab, and Luv. Calculate Correlated Color Temperature (CCT) and the Planckian and daylight loci. The XYZs of some standard illuminants and some standard linear chromatic adaptation transforms (CATs) are included. Three standard color difference metrics are included, plus the forward direction of the CIECAM02 color appearance model.

This package provides a facility to generate sliced (orthogonal) Latin hypercube designs with four and five slices. For details about sliced and orthogonal Latin hypercube designs, see Yang, J. F., Lin, C. D., Qian, P. Z., and Lin, D. K. (2013). "Construction of sliced orthogonal Latin hypercube designs". Statistica Sinica, 1117-1130, <doi:10.5705/ss.2012.037>.

Create highly customized tables with this simple and dependency-free package. Data frames can be converted to HTML', LaTeX', Markdown', Word', PNG', PDF', or Typst tables. The user interface is minimalist and easy to learn. The syntax is concise. HTML tables can be customized using the flexible Bootstrap framework, and LaTeX code with the tabularray package.

Bindings for the Tabula <https://tabula.technology/> Java library, which can extract tables from PDF files. This tool can reduce time and effort in data extraction processes in fields like investigative journalism. It allows for automatic and manual table extraction, the latter facilitated through a Shiny interface, enabling manual areas selection\ with a computer mouse for data retrieval.

This package provides a set of wrappers intended to check, read and download information from the Wikimedia sources. It is specifically created to work with names of celebrities, in which case their information and statistics can be downloaded. Additionally, it also builds links and snippets to use in combination with the function gallery() in netCoin package.

MethylSig is a package for testing for differentially methylated cytosines (DMCs) or regions (DMRs) in whole-genome bisulfite sequencing (WGBS) or reduced representation bisulfite sequencing (RRBS) experiments. MethylSig uses a beta binomial model to test for significant differences between groups of samples. Several options exist for either site-specific or sliding window tests, and variance estimation.

This package contains data required to run examples in prebs package. The data files include: 1) Small sample bam files for demonstration purposes 2) Probe sequence mappings for Custom CDF (taken from http://brainarray.mbni.med.umich.edu/brainarray/Database/CustomCDF/genomic_curated_CDF.asp) 3) Probe sequence mappings for manufacturer's CDF (manually created using bowtie).

This package implements several functions useful for analysis of gene expression data by sequencing tags as done in SAGE (Serial Analysis of Gene Expressen) data, i.e. extraction of a SAGE library from sequence files, sequence error correction, library comparison. Sequencing error correction is implementing using an Expectation Maximization Algorithm based on a Mixture Model of tag counts.

The main function kcca implements a general framework for k-centroids cluster analysis supporting arbitrary distance measures and centroid computation. Further cluster methods include hard competitive learning, neural gas, and QT clustering. There are numerous visualization methods for cluster results (neighborhood graphs, convex cluster hulls, barcharts of centroids, ...), and bootstrap methods for the analysis of cluster stability.