DoReMiTra is an R data package providing access to curated transcriptomic datasets related to blood radiation, with a focus on neutron, x-ray, and gamma ray studies. It is designed to facilitate radiation biology research and support data exploration and reproducibility in radiation transcriptomics. All datasets are provided as SummarizedExperiment objects, allowing seamless integration with the Bioconductor ecosystem.
Pathifier is an algorithm that infers pathway deregulation scores for each tumor sample on the basis of expression data. This score is determined, in a context-specific manner, for every particular dataset and type of cancer that is being investigated. The algorithm transforms gene-level information into pathway-level information, generating a compact and biologically relevant representation of each sample.
The complexity of high-throughput quantitative omics experiments often leads to low replicates numbers and many missing values. We implemented a new test to simultaneously consider missing values and quantitative changes, which we combined with well-performing statistical tests for high confidence detection of differentially regulated features. The package contains functions to run the test and to visualize the results.
Obtain overlapping clustering models for object-by-variable data matrices using the Additive Profile Clustering (ADPROCLUS) method. Also contains the low dimensional ADPROCLUS method for simultaneous dimension reduction and overlapping clustering. For reference see Depril, Van Mechelen, Mirkin (2008) <doi:10.1016/j.csda.2008.04.014> and Depril, Van Mechelen, Wilderjans (2012) <doi:10.1007/s00357-012-9112-5>.
Read and process brand.yml YAML files. brand.yml is a simple, portable YAML file that codifies your company's brand guidelines into a format that can be used by Quarto', Shiny and R tooling to create branded outputs. Maintain unified, branded theming for web applications to printed reports to dashboards and presentations with a consistent look and feel.
Transform newswire and earnings call transcripts as PDF obtained from Nexis Uni to R data frames. Various newswires and FairDisclosure earnings call formats are supported. Further, users can apply several pre-defined dictionaries on the data based on Graffin et al. (2016)<doi:10.5465/amj.2013.0288> and Gamache et al. (2015)<doi:10.5465/amj.2013.0377>.
This extension of the pattern-oriented modeling framework of the poems package provides a collection of modules and functions customized for modeling disease transmission on a population scale in a spatiotemporally explicit manner. This includes seasonal time steps, dispersal functions that track disease state of dispersers, results objects that store disease states, and a population simulator that includes disease dynamics.
This package provides dual-stroke and contrast-aware extensions to ggplot2', designed for improved visibility and accessibility in complex visualizations. Includes geoms for dual-stroke segments, regression lines, curved annotations, function plots, paths, and adaptive text. Also includes utility functions for computing contrast-aware color pairs and perceptually distinct highlight palettes using Web Content Accessibility Guidelines (WCAG)-based contrast logic.
This package implements the Leunbach test equating method, following the DIGRAM software written by Svend Kreiner. Both direct and indirect equating are available, with parametric bootstrap standard errors and diagnostic statistics including the Goodman-Kruskal gamma test and orbit analysis for person fit. See Adroher et al. (2019) <doi:10.1186/s12874-019-0768-y> for details of the method.
Long non-coding RNAs identification and analysis. Default models are trained with human, mouse and wheat datasets by employing SVM. Features are based on intrinsic composition of sequence, EIIP value (electron-ion interaction pseudopotential), and secondary structure. This package can also extract other classic features and build new classifiers. Reference: Han S., et al. (2019) <doi:10.1093/bib/bby065>.
Stand-alone HTTP capable R-package repository, that fully supports R's install.packages() and available.packages(). It also contains API endpoints for end-users to add/update packages. This package can supplement miniCRAN', which has functions for maintaining a local (partial) copy of CRAN'. Current version is bare-minimum without any access-control or much security.
Set of utility functions to interact with WeMo Switch', a smart plug that can be remotely controlled via wifi. The provided functions make it possible to turn one or more WeMo Switch plugs on and off in a scriptable fashion. More information about WeMo Switch can be found at <http://www.belkin.com/us/p/P-F7C027/>.
Simulation and estimation for Neyman-Scott spatial cluster point process models and their extensions, based on the methodology in Tanaka, Ogata, and Stoyan (2008) <doi:10.1002/bimj.200610339>. To estimate parameters by the simplex method, parallel computation using OpenMP application programming interface is available. For more details see Tanaka, Saga and Nakano <doi:10.18637/jss.v098.i06>.
Ordnance Survey ('OS') is the national mapping agency for Great Britain and produces a large variety of mapping and geospatial products. Much of OS's data is available via the OS Data Hub <https://osdatahub.os.uk/>, a platform that hosts both free and premium data products. osdatahub provides a user-friendly way to access, query, and download these data.
For the problem of indirect treatment comparison with limited subject-level data, this package provides tools for model-based standardisation with several different computation approaches. See Remiroâ Azócar A, Heath A, Baio G (2022) ``Parametric Gâ computation for compatible indirect treatment comparisons with limited individual patient data'', Res. Synth. Methods, 1â 31. ISSN 1759-2879, <doi:10.1002/jrsm.1565>.
Social media sites often embed cards when links are shared, based on metadata in the Open Graph Protocol (<https://ogp.me/>). This supports extracting that metadata from a website. It further allows for the creation of tags to add to a website to support the Open Graph Protocol and provides a list of the standard tags and their required properties.
An R client for the PaddleOCR cloud service API <https://www.paddleocr.ai/latest/en/version3.x/inference_deployment/serving/paddleocr_official_api/overview.html>. Submit images, PDFs, or URLs for OCR processing using models like PaddleOCR-VL-1.6'. Supports job submission, polling, result retrieval, automatic image download, and streaming PDF-to-markdown conversion with batch processing.
Propagation of uncertainty using higher-order Taylor expansion and Monte Carlo simulation. Calculations of propagated uncertainties are based on matrix calculus including covariance structure according to Arras 1998 <doi:10.3929/ethz-a-010113668> (first order), Wang & Iyer 2005 <doi:10.1088/0026-1394/42/5/011> (second order) and BIPM Supplement 1 (Monte Carlo) <doi:10.59161/JCGM101-2008>.
This package implements the SelectSim methodology for identifying patterns of co-occurrence and mutual exclusivity between functional genomic alterations in cancer cohorts. The package processes mutation annotation data, constructs alteration matrices, estimates expected alteration-pair frequencies, and quantifies deviations associated with selective interactions. The methodology is described in Iyer et al. (2026) <doi:10.1038/s41588-026-02661-4>.
Fits semiparametric linear and multilevel models with non-parametric additive Bayesian additive regression tree (BART; Chipman, George, and McCulloch (2010) <doi:10.1214/09-AOAS285>) components and Stan (Stan Development Team (2021) <https://mc-stan.org/>) sampled parametric ones. Multilevel models can be expressed using lme4 syntax (Bates, Maechler, Bolker, and Walker (2015) <doi:10.18637/jss.v067.i01>).
This package provides an implementation of the Sparse ICA method in Wang et al. (2024) <doi:10.1080/01621459.2024.2370593> for estimating sparse independent source components of cortical surface functional MRI data, by addressing a non-smooth, non-convex optimization problem through the relax-and-split framework. This method effectively balances statistical independence and sparsity while maintaining computational efficiency.
This is a collection of various kinds of data with broad uses for teaching. My students, and academics like me who teach the same topics I teach, should find this useful if their teaching workflow is also built around the R programming language. The applications are multiple but mostly cluster on topics of statistical methodology, international relations, and political economy.
Standalone R implementation of habitat connectivity corridor optimization for raster and vector workflows. Supports scenario-based planning with budget-constrained optimization, optional impassable areas, packaged parity fixtures, and comparative before-and-after connectivity metrics. The package exposes structural, movement-oriented, and species-oriented strategies in a reproducible workflow aligned with a companion GIS plugin while avoiding a desktop GIS dependency.
This package provides a container for data used by the usmap package. The data used by usmap has been extracted into this package so that the file size of the usmap package can be reduced greatly. The data in this package will be updated roughly once per year as new map data files are provided by the US Census Bureau.