Simplifies functions to conduct univariate, bivariate, and multivariate statistical techniques. Includes functions designed to replicate plots and tables that would result from similar calls in SPSS', including hst(), box(), qq(), tab(), cormat(), and residplot(). Also includes simplified formulae, such as mode(), scatter(), p.corr(), ow.anova(), and rm.anova().

Full model selection (detection of the relevant features and estimation of the number of clusters) for model-based clustering (see reference here <doi:10.1007/s11222-016-9670-1>). Data to analyze can be continuous, categorical, integer or mixed. Moreover, missing values can occur and do not necessitate any pre-processing. Shiny application permits an easy interpretation of the results.

The goal of NicheNet is to study intercellular communication from a computational perspective. NicheNet uses human or mouse gene expression data of interacting cells as input and combines this with a prior model that integrates existing knowledge on ligand-to-target signaling paths. This allows to predict ligand-receptor interactions that might drive gene expression changes in cells of interest.

RegulonDB has collected, harmonized and centralized data from hundreds of experiments for nearly two decades and is considered a point of reference for transcriptional regulation in Escherichia coli K12. Here, we present the regutools R package to facilitate programmatic access to RegulonDB data in computational biology. regutools provides researchers with the possibility of writing reproducible workflows with automated queries to RegulonDB. The regutools package serves as a bridge between RegulonDB data and the Bioconductor ecosystem by reusing the data structures and statistical methods powered by other Bioconductor packages. We demonstrate the integration of regutools with Bioconductor by analyzing transcription factor DNA binding sites and transcriptional regulatory networks from RegulonDB. We anticipate that regutools will serve as a useful building block in our progress to further our understanding of gene regulatory networks.

This package provides ggplot2 geoms filled with various patterns. It includes a patterned version of every ggplot2 geom that has a region that can be filled with a pattern. It provides a suite of ggplot2 aesthetics and scales for controlling pattern appearances. It supports over a dozen builtin patterns (every pattern implemented by gridpattern) as well as allowing custom user-defined patterns.

Provides implementations of functions which have been introduced in R since version 3.0.0. The backports are conditionally exported which results in R resolving the function names to the version shipped with R (if available) and uses the implemented backports as fallback. This way package developers can make use of the new functions without worrying about the minimum required R version.

This package provides functions to build tables with advanced layout elements such as row spanners, column spanners, table spanners, zebra striping, and more. While allowing advanced layout, the underlying CSS-structure is simple in order to maximize compatibility with word processors such as LibreOffice. The package also contains a few text formatting functions that help outputting text compatible with HTML or LaTeX.

OOMPA offers R packages for gene expression and proteomics analysis. OOMPA uses S4 classes to construct object-oriented tools with a consistent user interface. All higher level analysis tools in OOMPA are compatible with the eSet classes defined in BioConductor. The lower level processing tools offer an alternative to parts of BioConductor, but can also be used to enhance existing BioConductor packages.

RawTherapee is a raw image processing suite. It comprises a subset of image editing operations specifically aimed at non-destructive raw photo post-production and is primarily focused on improving a photographer's workflow by facilitating the handling of large numbers of images. Most raw formats are supported, including Pentax Pixel Shift, Canon Dual-Pixel, and those from Foveon and X-Trans sensors.

ClonalSim generates realistic mutational profiles of tumor samples with hierarchical clonal structure. It simulates founder, shared, and private mutations with biologically realistic noise models including intra-tumor heterogeneity (Beta distribution) and technical sequencing noise (negative binomial depth variation, binomial read sampling, base errors). The package is designed for benchmarking variant callers, testing clonal deconvolution algorithms, and teaching tumor heterogeneity concepts.

This package is an extension to CellNOptR. It contains additional functionality needed to simulate and train a prior knowledge network to experimental data using constrained fuzzy logic (cFL, rather than Boolean logic as is the case in CellNOptR). Additionally, this package will contain functions to use for the compilation of multiple optimization results (either Boolean or cFL).

gINTomics is an R package for Multi-Omics data integration and visualization. gINTomics is designed to detect the association between the expression of a target and of its regulators, taking into account also their genomics modifications such as Copy Number Variations (CNV) and methylation. What is more, gINTomics allows integration results visualization via a Shiny-based interactive app.

Assists in the set-up of algorithms for Bayesian inference of vector autoregressive (VAR) and error correction (VEC) models. Functions for posterior simulation, forecasting, impulse response analysis and forecast error variance decomposition are largely based on the introductory texts of Chan, Koop, Poirier and Tobias (2019, ISBN: 9781108437493), Koop and Korobilis (2010) <doi:10.1561/0800000013> and Luetkepohl (2006, ISBN: 9783540262398).

Designed to simplify the process of retrieving datasets from the Big Data PE platform using secure token-based authentication. It provides functions for securely storing, retrieving, and managing tokens associated with specific datasets, as well as fetching and processing data. The data-retrieval engine is provided by the generic apifetch package, which BigDataPE configures for the Big Data PE service.

Box-Cox-type transformations for linear and logistic models with random effects using non-parametric profile maximum likelihood estimation, as introduced in Almohaimeed (2018) <http://etheses.dur.ac.uk/12831/> and Almohaimeed and Einbeck (2022) <doi:10.1177/1471082X20966919>. The main functions are optim.boxcox() for linear models with random effects and boxcoxtype() for logistic models with random effects.

Compute ranking and rating based on competition results. Methods of different nature are implemented: with fixed Head-to-Head structure, with variable Head-to-Head structure and with iterative nature. All algorithms are taken from the book Whoâ s #1?: The science of rating and ranking by Amy N. Langville and Carl D. Meyer (2012, ISBN:978-0-691-15422-0).

Given a set of predictive quantiles from a distribution, estimate the distribution and create `d`, `p`, `q`, and `r` functions to evaluate its density function, distribution function, and quantile function, and generate random samples. On the interior of the provided quantiles, an interpolation method such as a monotonic cubic spline is used; the tails are approximated by a location-scale family.

This package provides an interactive viewer for data.frame', tibble and data.table objects using shiny <https://shiny.posit.co/> and DT <https://rstudio.github.io/DT/>. It supports complex filtering, column selection, and automatic generation of reproducible dplyr <https://dplyr.tidyverse.org/> code for data manipulation. The package is designed for ease of use in data exploration and reporting workflows.

Computes discrete fast Fourier transform of river discharge data and the derived metrics. The methods are described in J. L. Sabo, D. M. Post (2008) <doi:10.1890/06-1340.1> and J. L. Sabo, A. Ruhi, G. W. Holtgrieve, V. Elliott, M. E. Arias, P. B. Ngor, T. A. Räsänsen, S. Nam (2017) <doi:10.1126/science.aao1053>.

Test hypotheses and construct confidence intervals for AUC (area under Receiver Operating Characteristic curve) and pAUC (partial area under ROC curve), from the given two samples of test data with disease/healthy subjects. The method used is based on TWO SAMPLE empirical likelihood and PROFILE empirical likelihood, as described in <https://www.ms.uky.edu/~mai/research/eAUC1.pdf>.

An interactive shiny'-based tool for exploration and quality assurance and quality control (QA/QC) of eddy covariance flux tower data processing. It generates data-point removal code via user-directed selection from a scatterplot, and can export a cleaned .csv with removed points set to NA plus an R script for reproducibility. Reference: Key (2025) <DOI:10.5281/zenodo.15597159>.

Simulating single cell RNA-seq data with complicated structure. This package is developed based on the Splat method (Zappia, Phipson and Oshlack (2017) <doi:10.1186/s13059-017-1305-0>). GeneScape incorporates additional features to simulate single cell RNA-seq data with complicated differential expression and correlation structures, such as sub-cell-types, correlated genes (pathway genes) and hub genes.

Estimation of the cutpoint defined by the Generalized Symmetry point in a binary classification setting based on a continuous diagnostic test or marker. Two methods have been implemented to construct confidence intervals for this optimal cutpoint, one based on the Generalized Pivotal Quantity and the other based on Empirical Likelihood. Numerical and graphical outputs for these two methods are easily obtained.

Classifies hydraulic conditions into nominal fluvial mesohabitat categories using water depth and velocity. It implements the eight-class scheme in the preprint by Cordero and Harris <doi:10.2139/ssrn.7100727>, supports validated rectangular custom schemes, and works with tabular and spatial data through terra'. Outputs describe hydraulic classes and do not by themselves establish biological habitat quality or species occurrence.