This package provides a toolkit of high-level functions for DNA motif scanning and enrichment analysis built upon Biostrings. The main functionality is PWM enrichment analysis of already known PWMs (e.g. from databases such as MotifDb), but the package also implements high-level functions for PWM scanning and visualisation. The package does not perform "de novo" motif discovery, but is instead focused on using motifs that are either experimentally derived or computationally constructed by other tools.

This package performs a Gene Set Analysis with the approach adopted by PADOG on the genes that are reported as translationally regulated (ie. exhibit a significant change in TE) by the DeltaTE package. It can be used on its own to see the impact of translation regulation on gene sets, but it is also integrated as an additional analysis method within ReactomeGSA, where results are further contextualised in terms of pathways and directionality of the change.

This package provides functions for animations in statistics, covering topics in probability theory, mathematical statistics, multivariate statistics, non-parametric statistics, sampling survey, linear models, time series, computational statistics, data mining and machine learning. These functions may be helpful in teaching statistics and data analysis. Also provided in this package are a series of functions to save animations to various formats, e.g. GIF, HTML pages, PDF, and videos. PDF animations can be inserted into Sweave / knitr easily.

This package provides tools for working with rotational data, including simulation from the most commonly used distributions on SO(3), methods for different Bayes, mean and median type estimators for the central orientation of a sample, confidence/credible regions for the central orientation based on those estimators and a novel visualization technique for rotation data. Most recently, functions to identify potentially discordant (outlying) values have been added. References: Bingham, Melissa A. and Nordman, Dan J. and Vardeman, Steve B. (2009), Bingham, Melissa A and Vardeman, Stephen B and Nordman, Daniel J (2009), Bingham, Melissa A and Nordman, Daniel J and Vardeman, Stephen B (2010), Leon, C.A. and Masse, J.C. and Rivest, L.P. (2006), Hartley, R and Aftab, K and Trumpf, J. (2011), Stanfill, Bryan and Genschel, Ulrike and Hofmann, Heike (2013), Maonton, Jonathan (2004), Mardia, KV and Jupp, PE (2000, ISBN:9780471953333), Rancourt, D. and Rivest, L.P. and Asselin, J. (2000), Chang, Ted and Rivest, Louis-Paul (2001), Fisher, Nicholas I. (1996, ISBN:0521568900).

Extends ACER ConQuest through a family of functions designed to improve graphical outputs and help with advanced analysis (e.g., differential item functioning). Allows R users to call ACER ConQuest from within R and read ACER ConQuest System Files (generated by the command `put` <https://conquestmanual.acer.org/s4-00.html#put>). Requires ACER ConQuest version 5.40 or later. A demonstration version can be downloaded from <https://shop.acer.org/acer-conquest-5.html>.

This package provides R bindings to the dockview JavaScript library <https://dockview.dev/>. Create fully customizable grid layouts (docks) in seconds to include in interactive R reports with R Markdown or Quarto or in shiny apps <https://shiny.posit.co/>. In shiny mode, modify docks by dynamically adding, removing or moving panels or groups of panels from the server function. Choose among 8 stunning themes (dark and light), serialise the state of a dock to restore it later.

Using variational techniques we address some epidemiological problems as the incidence curve decomposition by inverting the renewal equation as described in Alvarez et al. (2021) <doi:10.1073/pnas.2105112118> and Alvarez et al. (2022) <doi:10.3390/biology11040540> or the estimation of the functional relationship between epidemiological indicators. We also propose a learning method for the short time forecast of the trend incidence curve as described in Morel et al. (2022) <doi:10.1101/2022.11.05.22281904>.

This package contains four main functions (i.e., four pieces of furniture): table1() which produces a well-formatted table of descriptive statistics common as Table 1 in research articles, tableC() which produces a well-formatted table of correlations, tableF() which provides frequency counts, and washer() which is helpful in cleaning up the data. These furniture-themed functions are designed to simplify common tasks in quantitative analysis. Other data summary and cleaning tools are also available.

When you prepare a presentation or a report, you often need to manage a large number of ggplot figures. You need to change the figure size, modify the title, label, themes, etc. It is inconvenient to go back to the original code to make these changes. This package provides a simple way to manage ggplot figures. You can easily add the figure to the database and update them later using CLI (command line interface) or GUI (graphical user interface).

This package creates presentation-ready tables summarizing data sets, regression models, and more. The code to create the tables is concise and highly customizable. Data frames can be summarized with any function, e.g. mean(), median(), even user-written functions. Regression models are summarized and include the reference rows for categorical variables. Common regression models, such as logistic regression and Cox proportional hazards regression, are automatically identified and the tables are pre-filled with appropriate column headers.

Offers an easy and automated way to scale up individual-level space use analysis to that of groups. Contains a function from the move package to calculate a dynamic Brownian bridge movement model from movement data for individual animals, as well as functions to visualize and quantify space use for individuals aggregated in groups. Originally written with passive acoustic telemetry in mind, this package also provides functionality to account for unbalanced acoustic receiver array designs, and satellite tag data.

Bayesian inference analysis for bivariate meta-analysis of diagnostic test studies using integrated nested Laplace approximation with INLA. A purpose built graphic user interface is available. The installation of R package INLA is compulsory for successful usage. The INLA package can be obtained from <https://www.r-inla.org>. We recommend the testing version, which can be downloaded by running: install.packages("INLA", repos=c(getOption("repos"), INLA="https://inla.r-inla-download.org/R/testing"), dep=TRUE).

This package provides a set of functions to build a scoring model from beginning to end, leading the user to follow an efficient and organized development process, reducing significantly the time spent on data exploration, variable selection, feature engineering, binning and model selection among other recurrent tasks. The package also incorporates monotonic and customized binning, scaling capabilities that transforms logistic coefficients into points for a better business understanding and calculates and visualizes classic performance metrics of a classification model.

This package provides tools for obtaining, processing, and visualizing spectral reflectance data for the user-defined land or water surface classes for visual exploring in which wavelength the classes differ. Input should be a shapefile with polygons of surface classes (it might be different habitat types, crops, vegetation, etc.). The Sentinel-2 L2A satellite mission optical bands pixel data are obtained through the Google Earth Engine service (<https://earthengine.google.com/>) and used as a source of spectral data.

The `scorecard` package makes the development of credit risk scorecard easier and efficient by providing functions for some common tasks, such as data partition, variable selection, woe binning, scorecard scaling, performance evaluation and report generation. These functions can also used in the development of machine learning models. The references including: 1. Refaat, M. (2011, ISBN: 9781447511199). Credit Risk Scorecard: Development and Implementation Using SAS. 2. Siddiqi, N. (2006, ISBN: 9780471754510). Credit risk scorecards. Developing and Implementing Intelligent Credit Scoring.

Collection of phylogenetic tree statistics, collected throughout the literature. All functions have been written to maximize computation speed. The package includes umbrella functions to calculate all statistics, all balance associated statistics, or all branching time related statistics. Furthermore, the treestats package supports summary statistic calculations on Ltables, provides speed-improved coding of branching times, Ltable conversion and includes algorithms to create intermediately balanced trees. Full description can be found in Janzen (2024) <doi:10.1016/j.ympev.2024.108168>.

An implementation of the 1-Sample Wilcoxon Sign rank test for medians. It includes 2 functions, W_stat(), which computes the exact probabilities of the Wilcoxon Sign Rank Test Statistic, W. The second function, Wilcox.m.test() allows the user to conduct the 1-Sample Wilcoxon Sign Rank hypothesis test for medians, this also allows the user to conduct the hypothesis test for the normal approximation, based on the techniques of Bickel and Doksum (1973, ISBN:013850363X).

This package produces metagene plots to compare coverages of sequencing experiments at selected groups of genomic regions. It can be used for such analyses as assessing the binding of DNA-interacting proteins at promoter regions or surveying antisense transcription over the length of a gene. The metagene2 package can manage all aspects of the analysis, from normalization of coverages to plot facetting according to experimental metadata. Bootstraping analysis is used to provide confidence intervals of per-sample mean coverages.

This package provides pathway enrichment techniques for miRNA expression data. Specifically, the set of methods handles the many-to-many relationship between miRNAs and the multiple genes they are predicted to target (and thus affect.) It also handles the gene-to-pathway relationships separately. Both steps are designed to preserve the additive effects of miRNAs on genes, many miRNAs affecting one gene, one miRNA affecting multiple genes, or many miRNAs affecting many genes.

seqsetvis enables the visualization and analysis of sets of genomic sites in next gen sequencing data. Although seqsetvis was designed for the comparison of mulitple ChIP-seq samples, this package is domain-agnostic and allows the processing of multiple genomic coordinate files (bed-like files) and signal files (bigwig files pileups from bam file). seqsetvis has multiple functions for fetching data from regions into a tidy format for analysis in data.table or tidyverse and visualization via ggplot2.

This package provides functions for estimating tolerance limits (intervals) for various univariate distributions (binomial, Cauchy, discrete Pareto, exponential, two-parameter exponential, extreme value, hypergeometric, Laplace, logistic, negative binomial, negative hypergeometric, normal, Pareto, Poisson-Lindley, Poisson, uniform, and Zipf-Mandelbrot), Bayesian normal tolerance limits, multivariate normal tolerance regions, nonparametric tolerance intervals, tolerance bands for regression settings (linear regression, nonlinear regression, nonparametric regression, and multivariate regression), and analysis of variance tolerance intervals. Visualizations are also available for most of these settings.

This package provides a collection of functions to compute the Rao-Stirling diversity index (Porter and Rafols, 2009) <DOI:10.1007/s11192-008-2197-2> and its extension to acknowledge missing data (i.e., uncategorized references) by calculating its interval of uncertainty using mathematical optimization as proposed in Calatrava et al. (2016) <DOI:10.1007/s11192-016-1842-4>. The Rao-Stirling diversity index is a well-established bibliometric indicator to measure the interdisciplinarity of scientific publications. Apart from the obligatory dataset of publications with their respective references and a taxonomy of disciplines that categorizes references as well as a measure of similarity between the disciplines, the Rao-Stirling diversity index requires a complete categorization of all references of a publication into disciplines. Thus, it fails for a incomplete categorization; in this case, the robust extension has to be used, which encodes the uncertainty caused by missing bibliographic data as an uncertainty interval. Classification / ACM - 2012: Information systems ~ Similarity measures, Theory of computation ~ Quadratic programming, Applied computing ~ Digital libraries and archives.

Computation of the alpha-shape and alpha-convex hull of a given sample of points in the plane. The concepts of alpha-shape and alpha-convex hull generalize the definition of the convex hull of a finite set of points. The programming is based on the duality between the Voronoi diagram and Delaunay triangulation. The package also includes a function that returns the Delaunay mesh of a given sample of points and its dual Voronoi diagram in one single object.

The AHP method (Analytic Hierarchy Process) is a multi-criteria decision-making method addressing choice and outranking problems. The method enables to perform the analysis of alternatives in each type of criterion and then provides a global performance of each alternative in the decision context. The main difference of this package is the possibility of evaluating the alternatives using quantitative data, by numerical representation, and qualitative data, using the Saaty scale, providing preference relation between variables by a pairwise evaluation.