This package provides pure C++ implementations for reading and writing several common data formats based on Google protocol-buffers. It currently supports rexp.proto for serialized R objects, geobuf.proto for binary geojson, and mvt.proto for vector tiles. This package uses the auto-generated C++ code by protobuf-compiler, hence the entire serialization is optimized at compile time. The RProtoBuf package on the other hand uses the protobuf runtime library to provide a general-purpose toolkit for reading and writing arbitrary protocol-buffer data in R.

Manage storage in Microsoft's Azure cloud: <https://azure.microsoft.com/en-us/product-categories/storage/>. On the admin side, AzureStor includes features to create, modify and delete storage accounts. On the client side, it includes an interface to blob storage, file storage, and Azure Data Lake Storage Gen2': upload and download files and blobs; list containers and files/blobs; create containers; and so on. Authenticated access to storage is supported, via either a shared access key or a shared access signature (SAS). Part of the AzureR family of packages.

Generates confidence intervals for standardized regression coefficients using delta method standard errors for models fitted by lm() as described in Yuan and Chan (2011) <doi:10.1007/s11336-011-9224-6> and Jones and Waller (2015) <doi:10.1007/s11336-013-9380-y>. The package can also be used to generate confidence intervals for differences of standardized regression coefficients and as a general approach to performing the delta method. A description of the package and code examples are presented in Pesigan, Sun, and Cheung (2023) <doi:10.1080/00273171.2023.2201277>.

Typical morphological profiling datasets have millions of cells and hundreds of features per cell. When working with this data, you must clean the data, normalize the features to make them comparable across experiments, transform the features, select features based on their quality, and aggregate the single-cell data, if needed. cytominer makes these steps fast and easy. Methods used in practice in the field are discussed in Caicedo (2017) <doi:10.1038/nmeth.4397>. An overview of the field is presented in Caicedo (2016) <doi:10.1016/j.copbio.2016.04.003>.

We provide a comprehensive software to estimate general K-stage DTRs from SMARTs with Q-learning and a variety of outcome-weighted learning methods. Penalizations are allowed for variable selection and model regularization. With the outcome-weighted learning scheme, different loss functions - SVM hinge loss, SVM ramp loss, binomial deviance loss, and L2 loss - are adopted to solve the weighted classification problem at each stage; augmentation in the outcomes is allowed to improve efficiency. The estimated DTR can be easily applied to a new sample for individualized treatment recommendations or DTR evaluation.

Allows for the specification of deep conditional transformation models (DCTMs) and ordinal neural network transformation models, as described in Baumann et al (2021) <doi:10.1007/978-3-030-86523-8_1> and Kook et al (2022) <doi:10.1016/j.patcog.2021.108263>. Extensions such as autoregressive DCTMs (Ruegamer et al, 2023, <doi:10.1007/s11222-023-10212-8>) and transformation ensembles (Kook et al, 2022, <doi:10.48550/arXiv.2205.12729>) are implemented. The software package is described in Kook et al (2024, <doi:10.18637/jss.v111.i10>).

This package provides a flexible framework for Agent-Based Models (ABM), the epiworldR package provides methods for prototyping disease outbreaks and transmission models using a C++ backend, making it very fast. It supports multiple epidemiological models, including the Susceptible-Infected-Susceptible (SIS), Susceptible-Infected-Removed (SIR), Susceptible-Exposed-Infected-Removed (SEIR), and others, involving arbitrary mitigation policies and multiple-disease models. Users can specify infectiousness/susceptibility rates as a function of agents features, providing great complexity for the model dynamics. Furthermore, epiworldR is ideal for simulation studies featuring large populations.

Quantifies the provenance of the sediments in a catchment or study area. Based on a comprehensive characterization of the sediment sources and the end sediment mixtures a mixing model algorithm is applied to the sediment mixtures in order to estimate the relative contribution of each potential source. The package includes several statistical methods such as Kruskal-Wallis test, discriminant function analysis ('DFA'), principal component plot ('PCA') to select the optimal subset of tracer properties. The variability within each sediment source is also considered to estimate the statistical distribution of the sources contribution.

This package provides a comprehensive suite of functions for processing and visualizing taxonomic data. It includes functionality to clean and transform taxonomic data, categorize it into hierarchical ranks (such as Phylum, Class, Order, Family, and Genus), and calculate the relative abundance of each category. The package also generates a color palette for visual representation of the taxonomic data, allowing users to easily identify and differentiate between various taxonomic groups. Additionally, it features a river plot visualization to effectively display the distribution of individuals across different taxonomic ranks, facilitating insights into taxonomic visualization.

This package contains miscellaneous functions useful for managing NetCDF files (see <https://en.wikipedia.org/wiki/NetCDF>), get moon phase and time for sun rise and fall, tide level, analyse and reconstruct periodic time series of temperature with irregular sinusoidal pattern, show scales and wind rose in plot with change of color of text, Metropolis-Hastings algorithm for Bayesian MCMC analysis, plot graphs or boxplot with error bars, search files in disk by there names or their content, read the contents of all files from a folder at one time.

Automate the detection of gaps and elevations in mapped sequencing read coverage using a 2D pattern-matching algorithm. ProActive detects, characterizes and visualizes read coverage patterns in both genomes and metagenomes. Optionally, users may provide gene annotations associated with their genome or metagenome in the form of a .gff file. In this case, ProActive will generate an additional output table containing the gene annotations found within the detected regions of gapped and elevated read coverage. Additionally, users can search for gene annotations of interest in the output read coverage plots.

This package provides tools for profiling a user-supplied log-likelihood function to calculate confidence intervals for model parameters. Speed of computation can be improved by adjusting the step sizes in the profiling and/or starting the profiling from limits based on the approximate large sample normal distribution for the maximum likelihood estimator of a parameter. The accuracy of the limits can be set by the user. A plot method visualises the log-likelihood and confidence interval. Only convex log-likelihoods are supported, that is, disjoint confidence intervals will not be found.

It estimates the parameters of a censored or missing data in spatio-temporal models using the SAEM algorithm (Delyon et al., 1999). This algorithm is a stochastic approximation of the widely used EM algorithm and an important tool for models in which the E-step does not have an analytic form. Besides the expressions obtained to estimate the parameters to the proposed model, we include the calculations for the observed information matrix using the method developed by Louis (1982). To examine the performance of the fitted model, case-deletion measure are provided.

Efficient Markov chain Monte Carlo (MCMC) algorithms for fully Bayesian estimation of time-varying parameter models with shrinkage priors, both dynamic and static. Details on the algorithms used are provided in Bitto and Frühwirth-Schnatter (2019) <doi:10.1016/j.jeconom.2018.11.006> and Cadonna et al. (2020) <doi:10.3390/econometrics8020020> and Knaus and Frühwirth-Schnatter (2023) <doi:10.48550/arXiv.2312.10487>. For details on the package, please see Knaus et al. (2021) <doi:10.18637/jss.v100.i13>. For the multivariate extension, see the shrinkTVPVAR package.

Machine learning provides algorithms that can learn from data and make inferences or predictions. Stochastic automata is a class of input/output devices which can model components. This work provides implementation an inference algorithm for stochastic automata which is similar to the Viterbi algorithm. Moreover, we specify a learning algorithm using the expectation-maximization technique and provide a more efficient implementation of the Baum-Welch algorithm for stochastic automata. This work is based on Inference and learning in stochastic automata was by Karl-Heinz Zimmermann(2017) <doi:10.12732/ijpam.v115i3.15>.

This package provides a Shiny app for visual exploration of omic datasets as compositions, and differential abundance analysis using ALDEx2. Useful for exploring RNA-seq, meta-RNA-seq, 16s rRNA gene sequencing with visualizations such as principal component analysis biplots (coloured using metadata for visualizing each variable), dendrograms and stacked bar plots, and effect plots (ALDEx2). Input is a table of counts and metadata file (if metadata exists), with options to filter data by count or by metadata to remove low counts, or to visualize select samples according to selected metadata.

SpotClean is a computational method to adjust for spot swapping in spatial transcriptomics data. Recent spatial transcriptomics experiments utilize slides containing thousands of spots with spot-specific barcodes that bind mRNA. Ideally, unique molecular identifiers at a spot measure spot-specific expression, but this is often not the case due to bleed from nearby spots, an artifact we refer to as spot swapping. SpotClean is able to estimate the contamination rate in observed data and decontaminate the spot swapping effect, thus increase the sensitivity and precision of downstream analyses.

This package provides a simple tool to quantify the amount of transmission of an infectious disease of interest occurring within and between population groups. bumblebee uses counts of observed directed transmission pairs, identified phylogenetically from deep-sequence data or from epidemiological contacts, to quantify transmission flows within and between population groups accounting for sampling heterogeneity. Population groups might include: geographical areas (e.g. communities, regions), demographic groups (e.g. age, gender) or arms of a randomized clinical trial. See the bumblebee website for statistical theory, documentation and examples <https://magosil86.github.io/bumblebee/>.

Color values in R are often represented as strings of hexadecimal colors or named colors. This package offers fast conversion of these color representations to either an array of red/green/blue/alpha values or to the packed integer format used in native raster objects. Functions for conversion are also exported at the C level for use in other packages. This fast conversion of colors is implemented using an order-preserving minimal perfect hash derived from Majewski et al (1996) "A Family of Perfect Hashing Methods" <doi:10.1093/comjnl/39.6.547>.

Grey zones locally occur in an agreement table due to the subjective evaluation of raters based on various factors such as not having uniform guidelines, the differences between the raters level of expertise or low variability among the level of the categorical variable. It is important to detect grey zones since they cause a negative bias in the estimate of the agreement level. This package provides a function for detecting the existence of grey zones in two-way inter-rater agreement tables (Demirhan and Yilmaz (2023) <doi:10.1186/s12874-022-01759-7>).

The purpose is to account for the random displacements (jittering) of true survey household cluster center coordinates in geostatistical analyses of Demographic and Health Surveys program (DHS) data. Adjustment for jittering can be implemented either in the spatial random effect, or in the raster/distance based covariates, or in both. Detailed information about the methods behind the package functionality can be found in two preprints. Umut Altay, John Paige, Andrea Riebler, Geir-Arne Fuglstad (2022) <arXiv:2202.11035v2>. Umut Altay, John Paige, Andrea Riebler, Geir-Arne Fuglstad (2022) <arXiv:2211.07442v1>.

Class imbalance usually damages the performance of classifiers. Thus, it is important to treat data before applying a classifier algorithm. This package includes recent resampling algorithms in the literature: (Barua et al. 2014) <doi:10.1109/tkde.2012.232>; (Das et al. 2015) <doi:10.1109/tkde.2014.2324567>, (Zhang et al. 2014) <doi:10.1016/j.inffus.2013.12.003>; (Gao et al. 2014) <doi:10.1016/j.neucom.2014.02.006>; (Almogahed et al. 2014) <doi:10.1007/s00500-014-1484-5>. It also includes an useful interface to perform oversampling.

Analysis of dichotomous and continuous response data using latent factor by both 1PL LSIRM and 2PL LSIRM as described in Jeon et al. (2021) <doi:10.1007/s11336-021-09762-5>. It includes original 1PL LSIRM and 2PL LSIRM provided for binary response data and its extension for continuous response data. Bayesian model selection with spike-and-slab prior and method for dealing data with missing value under missing at random, missing completely at random are also supported. Various diagnostic plots are available to inspect the latent space and summary of estimated parameters.

Vitamin and mineral deficiencies continue to be a significant public health problem. This is particularly critical in developing countries where deficiencies to vitamin A, iron, iodine, and other micronutrients lead to adverse health consequences. Cross-sectional surveys are helpful in answering questions related to the magnitude and distribution of deficiencies of selected vitamins and minerals. This package provides tools for calculating and determining select vitamin and mineral deficiencies based on World Health Organization (WHO) guidelines found at <https://www.who.int/teams/nutrition-and-food-safety/databases/vitamin-and-mineral-nutrition-information-system>.