Evaluate a function across a grid of parameters. The function may be evaluated once, or many times for simulation. Parallel computing is facilitated. Utilities aim at performing analyses of power and sample size, allowing for easy search of minimum n (or min/max of any other parameter) to achieve a desired minimal level of power (or maximum of any other objective). Plotting functions are included that present the dependency of n and power in relation to further assumptions.

Find non-linear formulas that fits your input data. You can systematically explore and memorize the possible formulas and it's cross-validation performance, in an incremental fashion. Three main interoperable search functions are available: 1) random.search() performs a random exploration, 2) genetic.search() employs a genetic optimization algorithm, 3) comb.search() combines best results of the first two. For more details see Tomasoni et al. (2026) <doi:10.1208/s12248-026-01232-z>.

Create sets of variables based on a mutual information approach. In this context, a set is a collection of distinct elements (e.g., variables) that can also be treated as a single entity. Mutual information, a concept from probability theory, quantifies the dependence between two variables by expressing how much information about one variable can be gained from observing the other. Furthermore, you can analyze, and visualize these sets in order to better understand the relationships among variables.

Generates interactive plots for analysing and visualising three-class high dimensional data. It is particularly suited to visualising differences in continuous attributes such as gene/protein/biomarker expression levels between three groups. Differential gene/biomarker expression analysis between two classes is typically shown as a volcano plot. However, with three groups this type of visualisation is particularly difficult to interpret. This package generates 3D volcano plots and 3-way polar plots for easier interpretation of three-class data.

This package provides a collection of functions to compute the Rao-Stirling diversity index (Porter and Rafols, 2009) <DOI:10.1007/s11192-008-2197-2> and its extension to acknowledge missing data (i.e., uncategorized references) by calculating its interval of uncertainty using mathematical optimization as proposed in Calatrava et al. (2016) <DOI:10.1007/s11192-016-1842-4>. The Rao-Stirling diversity index is a well-established bibliometric indicator to measure the interdisciplinarity of scientific publications. Apart from the obligatory dataset of publications with their respective references and a taxonomy of disciplines that categorizes references as well as a measure of similarity between the disciplines, the Rao-Stirling diversity index requires a complete categorization of all references of a publication into disciplines. Thus, it fails for a incomplete categorization; in this case, the robust extension has to be used, which encodes the uncertainty caused by missing bibliographic data as an uncertainty interval. Classification / ACM - 2012: Information systems ~ Similarity measures, Theory of computation ~ Quadratic programming, Applied computing ~ Digital libraries and archives.

This package provides a wrapper for several FFTW functions. It provides access to the two-dimensional FFT, the multivariate FFT, and the one-dimensional real to complex FFT using the FFTW3 library. The package includes the functions fftw() and mvfftw() which are designed to mimic the functionality of the R functions fft() and mvfft(). The FFT functions have a parameter that allows them to not return the redundant complex conjugate when the input is real data.

Coralysis is an R package featuring a multi-level integration algorithm for sensitive integration, reference-mapping, and cell-state identification in single-cell data. The multi-level integration algorithm is inspired by the process of assembling a puzzle - where one begins by grouping pieces based on low-to high-level features, such as color and shading, before looking into shape and patterns. This approach progressively blends the batch effects and separates cell types across multiple rounds of divisive clustering.

This package produces metagene plots to compare coverages of sequencing experiments at selected groups of genomic regions. It can be used for such analyses as assessing the binding of DNA-interacting proteins at promoter regions or surveying antisense transcription over the length of a gene. The metagene2 package can manage all aspects of the analysis, from normalization of coverages to plot facetting according to experimental metadata. Bootstraping analysis is used to provide confidence intervals of per-sample mean coverages.

This package provides pathway enrichment techniques for miRNA expression data. Specifically, the set of methods handles the many-to-many relationship between miRNAs and the multiple genes they are predicted to target (and thus affect.) It also handles the gene-to-pathway relationships separately. Both steps are designed to preserve the additive effects of miRNAs on genes, many miRNAs affecting one gene, one miRNA affecting multiple genes, or many miRNAs affecting many genes.

seqsetvis enables the visualization and analysis of sets of genomic sites in next gen sequencing data. Although seqsetvis was designed for the comparison of mulitple ChIP-seq samples, this package is domain-agnostic and allows the processing of multiple genomic coordinate files (bed-like files) and signal files (bigwig files pileups from bam file). seqsetvis has multiple functions for fetching data from regions into a tidy format for analysis in data.table or tidyverse and visualization via ggplot2.

This package provides functions to conduct title and abstract screening in systematic reviews using large language models, such as the Generative Pre-trained Transformer (GPT) models from OpenAI <https://developers.openai.com/>. These functions can enhance the quality of title and abstract screenings while reducing the total screening time significantly. In addition, the package includes tools for quality assessment of title and abstract screenings, as described in Vembye, Christensen, Mølgaard, and Schytt (2025) <DOI:10.1037/met0000769>.

Computes Ball-codifference scores and performs sure independence screening for high-dimensional predictors. The score combines random-ball empirical probabilities with a bounded local codifference weight based on trigonometric characteristic-function contrasts. The functions are intended for marginal screening when moment-based dependence summaries may be unstable or undefined, such as in heavy-tailed data. The implemented methodology is described in Rezapour and Maroufy (2026) "Ball-Codifference Screening for Heavy-Tailed Predictors" <doi:10.48550/arXiv.2607.20821>.

Extends ACER ConQuest through a family of functions designed to improve graphical outputs and help with advanced analysis (e.g., differential item functioning). Allows R users to call ACER ConQuest from within R and read ACER ConQuest System Files (generated by the command `put` <https://conquestmanual.acer.org/s4-00.html#put>). Requires ACER ConQuest version 5.40 or later. A demonstration version can be downloaded from <https://shop.acer.org/acer-conquest-5.html>.

This package provides R bindings to the dockview JavaScript library <https://dockview.dev/>. Create fully customizable grid layouts (docks) in seconds to include in interactive R reports with R Markdown or Quarto or in shiny apps <https://shiny.posit.co/>. In shiny mode, modify docks by dynamically adding, removing or moving panels or groups of panels from the server function. Choose among 8 stunning themes (dark and light), serialise the state of a dock to restore it later.

Using variational techniques we address some epidemiological problems as the incidence curve decomposition by inverting the renewal equation as described in Alvarez et al. (2021) <doi:10.1073/pnas.2105112118> and Alvarez et al. (2022) <doi:10.3390/biology11040540> or the estimation of the functional relationship between epidemiological indicators. We also propose a learning method for the short time forecast of the trend incidence curve as described in Morel et al. (2022) <doi:10.1101/2022.11.05.22281904>.

This package provides tools for analysis, visualization, and simulation of plant disease progress curves. Includes functions to calculate area-under-the-curve summaries, fit and compare exponential, monomolecular, logistic, and Gompertz models using linear or nonlinear regression, work with single or multiple epidemics, and produce ggplot2'-based visualizations. Also includes an experimental powdery mildew dataset for reproducible teaching and research workflows. See Madden, Hughes, and van den Bosch (2007) <doi:10.1094/9780890545058> for background on the epidemiological methods.

This package contains four main functions (i.e., four pieces of furniture): table1() which produces a well-formatted table of descriptive statistics common as Table 1 in research articles, tableC() which produces a well-formatted table of correlations, tableF() which provides frequency counts, and washer() which is helpful in cleaning up the data. These furniture-themed functions are designed to simplify common tasks in quantitative analysis. Other data summary and cleaning tools are also available.

This package creates presentation-ready tables summarizing data sets, regression models, and more. The code to create the tables is concise and highly customizable. Data frames can be summarized with any function, e.g. mean(), median(), even user-written functions. Regression models are summarized and include the reference rows for categorical variables. Common regression models, such as logistic regression and Cox proportional hazards regression, are automatically identified and the tables are pre-filled with appropriate column headers.

When you prepare a presentation or a report, you often need to manage a large number of ggplot figures. You need to change the figure size, modify the title, label, themes, etc. It is inconvenient to go back to the original code to make these changes. This package provides a simple way to manage ggplot figures. You can easily add the figure to the database and update them later using CLI (command line interface) or GUI (graphical user interface).

Bayesian inference analysis for bivariate meta-analysis of diagnostic test studies using integrated nested Laplace approximation with INLA. A purpose built graphic user interface is available. The installation of R package INLA is compulsory for successful usage. The INLA package can be obtained from <https://www.r-inla.org>. We recommend the testing version, which can be downloaded by running: install.packages("INLA", repos=c(getOption("repos"), INLA="https://inla.r-inla-download.org/R/testing"), dep=TRUE).

Splits initial strata into refined strata that optimize covariate balance. For more information, please see Brumberg, Small, and Rosenbaum (2024) <doi:10.1093/biomtc/ujae061>. To solve the linear program, the Gurobi commercial optimization software is recommended, but not required. The gurobi R package can be installed following the instructions at <https://docs.gurobi.com/projects/optimizer/en/current/reference/r/setup.html> after claiming your free academic license at <https://www.gurobi.com/academia/academic-program-and-licenses/>.

Fits a semiparametric spatiotemporal model for data with mixed frequencies, specifically where the response variable is observed at a lower frequency than some covariates. The estimation uses an iterative backfitting algorithm that combines a non-parametric smoothing spline for high-frequency data, parametric estimation for low-frequency and spatial neighborhood effects, and an autoregressive error structure. Methodology based on Malabanan, Lansangan, and Barrios (2022) <https://scienggj.org/2022/SciEnggJ%202022-vol15-no02-p90-107-Malabanan%20et%20al.pdf>.

Finds the vertex partition of an undirected graph that maximises a persistence-based objective, using the Milano local-search algorithm. Three related quality measures are supported: the persistence probability of a community, its null-adjusted persistence (NAP), and the scaled null-adjusted persistence (Scaled-NAP), which interpolates between NAP and modularity. The methods are described in Avellone et al. (2023) <doi:10.1007/s10288-023-00559-z> and Avellone et al. (2025) <doi:10.1016/j.ins.2025.123032>.

The `scorecard` package makes the development of credit risk scorecard easier and efficient by providing functions for some common tasks, such as data partition, variable selection, woe binning, scorecard scaling, performance evaluation and report generation. These functions can also used in the development of machine learning models. The references including: 1. Refaat, M. (2011, ISBN: 9781447511199). Credit Risk Scorecard: Development and Implementation Using SAS. 2. Siddiqi, N. (2006, ISBN: 9780471754510). Credit risk scorecards. Developing and Implementing Intelligent Credit Scoring.