Since the early 1970s eyewitness testimony researchers have recognised the importance of estimating properties such as lineup bias (is the lineup biased against the suspect, leading to a rate of choosing higher than one would expect by chance?), and lineup size (how many reasonable choices are in fact available to the witness? A lineup is supposed to consist of a suspect and a number of additional members, or foils, whom a poor-quality witness might mistake for the perpetrator). Lineup measures are descriptive, in the first instance, but since the earliest articles in the literature researchers have recognised the importance of reasoning inferentially about them. This package contains functions to compute various properties of laboratory or police lineups, and is intended for use by researchers in forensic psychology and/or eyewitness testimony research. Among others, the r4lineups package includes functions for calculating lineup proportion, functional size, various estimates of effective size, diagnosticity ratio, homogeneity of the diagnosticity ratio, ROC curves for confidence x accuracy data and the degree of similarity of faces in a lineup.

The commonly used methods for relative quantification of gene expression levels obtained in real-time PCR (Polymerase Chain Reaction) experiments are the delta Ct methods, encompassing 2^-dCt and 2^-ddCt methods, originally proposed by Kenneth J. Livak and Thomas D. Schmittgen (2001) <doi:10.1006/meth.2001.1262>. The main idea is to normalise gene expression values using endogenous control gene, present gene expression levels in linear form by using the 2^-(value)^ transformation, and calculate differences in gene expression levels between groups of samples (or technical replicates of a single sample). The RQdeltaCT package offers functions that cover both methods for comparison of either independent groups of samples or groups with paired samples, together with importing expression datasets, performing multi-step quality control of data, enabling numerous data visualisations, enrichment of the standard workflow with additional useful analyses (correlation analysis, Receiver Operating Characteristic analysis, logistic regression), and conveniently export obtained results in table and image formats. The package has been designed to be friendly to non-experts in R programming.

Capture Hi-C is a set of techniques that enable the detection of genomic interactions involving regions of interest, known as baits. By focusing on selected loci, these approaches reduce sequencing costs while maintaining high resolution at the level of restriction fragments. HiCaptuRe provides tools to import, annotate, manipulate, and export Capture Hi-C data. The package accounts for the specific structure of bait–otherEnd interactions, facilitates integration with other omics datasets, and enables comparison across samples and conditions.

pathlinkR is an R package designed to facilitate analysis of RNA-Seq results. Specifically, our aim with pathlinkR was to provide a number of tools which take a list of DE genes and perform different analyses on them, aiding with the interpretation of results. Functions are included to perform pathway enrichment, with muliplte databases supported, and tools for visualizing these results. Genes can also be used to create and plot protein-protein interaction networks, all from inside of R.

Image segmentation is the process of identifying the borders of individual objects (in this case cells) within an image. This allows for the features of cells such as marker expression and morphology to be extracted, stored and analysed. simpleSeg provides functionality for user friendly, watershed based segmentation on multiplexed cellular images in R based on the intensity of user specified protein marker channels. simpleSeg can also be used for the normalization of single cell data obtained from multiple images.

This package performs CACE (Complier Average Causal Effect analysis) on either a single study or meta-analysis of datasets with binary outcomes, using either complete or incomplete noncompliance information. Our package implements the Bayesian methods proposed in Zhou et al. (2019) <doi:10.1111/biom.13028>, which introduces a Bayesian hierarchical model for estimating CACE in meta-analysis of clinical trials with noncompliance, and Zhou et al. (2021) <doi:10.1080/01621459.2021.1900859>, with an application example on Epidural Analgesia.

This package provides a new robust principal component analysis algorithm is implemented that relies upon the Cauchy Distribution. The algorithm is suitable for high dimensional data even if the sample size is less than the number of variables. The methodology is described in this paper: Fayomi A., Pantazis Y., Tsagris M. and Wood A.T.A. (2024). "Cauchy robust principal component analysis with applications to high-dimensional data sets". Statistics and Computing, 34: 26. <doi:10.1007/s11222-023-10328-x>.

Fits convolution-based nonstationary Gaussian process models to point-referenced spatial data. The nonstationary covariance function allows the user to specify the underlying correlation structure and which spatial dependence parameters should be allowed to vary over space: the anisotropy, nugget variance, and process variance. The parameters are estimated via maximum likelihood, using a local likelihood approach. Also provided are functions to fit stationary spatial models for comparison, calculate the Kriging predictor and standard errors, and create various plots to visualize nonstationarity.

Produce Kaplanâ Meier plots in the style recommended following the KMunicate study by Morris et al. (2019) <doi:10.1136/bmjopen-2019-030215>. The KMunicate style consists of Kaplan-Meier curves with confidence intervals to quantify uncertainty and an extended risk table (per treatment arm) depicting the number of study subjects at risk, events, and censored observations over time. The resulting plots are built using ggplot2 and can be further customised to a certain extent, including themes, fonts, and colour scales.

This package implements the Lilliefors-corrected Kolmogorov-Smirnov test for use in goodness-of-fit tests, suitable when population parameters are unknown and must be estimated by sample statistics. P-values are estimated by simulation. Can be used with a variety of continuous distributions, including normal, lognormal, univariate mixtures of normals, uniform, loguniform, exponential, gamma, and Weibull distributions. Functions to generate random numbers and calculate density, distribution, and quantile functions are provided for use with the log uniform and mixture distributions.

Engaging the private sector in contraceptive method supply is critical for equitable, sustainable, and accessible healthcare systems. This package implements Bayesian hierarchical models to estimate public and private contraceptive supply shares over time at national and subnational levels, using Demographic and Health Survey (DHS) data. Penalized splines are used to track supply shares over time, and spatial correlation structures link national and subnational estimates in data- sparse settings. For more details see Comiskey (2025) <doi:10.48550/arXiv.2510.25153>.

This package provides tools to import, clean, and visualize movement data, particularly from motion capture systems such as Optitrack's Motive', the Straw Lab's Flydra', or from other sources. We provide functions to remove artifacts, standardize tunnel position and tunnel axes, select a region of interest, isolate specific trajectories, fill gaps in trajectory data, and calculate 3D and per-axis velocity. For experiments of visual guidance, we also provide functions that use subject position to estimate perception of visual stimuli.

Aligns irregularly timed longitudinal observations to regular panel schedules. Each observation on a subject serves as a potential baseline, and all later observations are aligned to the nearest panel with minimal delay. The package provides tools to: (1) build a panel book documenting alignments and delays, (2) organize variables in longitudinal data to wide-format panel matrices, (3) summarize alignment quality and panel coverage. Ideal for cross-lagged panel analysis, clinical trials with variable visit schedules, and Electronic Health Record harmonization.

This package implements a spatial extension of the random forest algorithm (Georganos et al. (2019) <doi:10.1080/10106049.2019.1595177>). Provides a Geographically Weighted Random Forest regression and a routine to find the optimal bandwidth (Georganos and Kalogirou (2022) <doi:10.3390/ijgi11090471>). A lightweight cross-validation helper for tuning the mtry parameter of a random forest and a generator of synthetic spatial test data are also included. The package depends on ranger as its single random-forest back-end.

Propose an area-level, non-parametric regression estimator based on Nadaraya-Watson kernel on small area mean. Adopt a two-stage estimation approach proposed by Prasad and Rao (1990). Mean Squared Error (MSE) estimators are not readily available, so resampling method that called bootstrap is applied. This package are based on the model proposed in Two stage non-parametric approach for small area estimation by Pushpal Mukhopadhyay and Tapabrata Maiti(2004) <http://www.asasrms.org/Proceedings/y2004/files/Jsm2004-000737.pdf>.

This package provides a framework for text cleansing and analysis. Conveniently prepare and process large amounts of text for analysis. Includes various metrics for word counts/frequencies that scale efficiently. Quickly analyze large amounts of text data using a text.table (a data.table created with one word (or unit of text analysis) per row, similar to the tidytext format). Offers flexibility to efficiently work with text data stored in vectors as well as text data formatted as a text.table.

Fast and efficient computation of rolling and expanding eigenanalysis for time-series data. The rolleigen package decomposes the covariance matrix of the explanatory variables into eigenvalues and eigenvectors to perform principal component analysis (Pearson, 1901, <doi:10.1080/14786440109462720>; Hotelling, 1933, <doi:10.1037/h0071325>) and principal component regression (Massy, 1965, <doi:10.1080/01621459.1965.10480787>) over rolling and expanding windows. For each window, the eigenvalues and eigenvectors are computed from the covariance matrix and, optionally, ordered from largest to smallest to summarize the directions of greatest variation in the data. A subset of leading components is then used to fit a regression that mitigates collinearity in the explanatory variables. Use cases include dimensionality reduction, factor extraction, and regression on collinear explanatory variables. The package supports rolling and expanding windows, weights, and handling of missing values via the min_obs, complete_obs, and na_restore arguments. The implementation uses the online and offline algorithms from the roll package to compute rolling and expanding cross-products efficiently, with parallelism across columns and windows provided by RcppParallel'.

This package provides an efficient implementation of the K-Means++ algorithm. For more information see (1) "kmeans++ the advantages of the k-means++ algorithm" by David Arthur and Sergei Vassilvitskii (2007), Proceedings of the eighteenth annual ACM-SIAM symposium on Discrete algorithms, Society for Industrial and Applied Mathematics, Philadelphia, PA, USA, pp. 1027-1035, and (2) "The Effectiveness of Lloyd-Type Methods for the k-Means Problem" by Rafail Ostrovsky, Yuval Rabani, Leonard J. Schulman and Chaitanya Swamy <doi:10.1145/2395116.2395117>.

Genomic analysis can be utilised to identify differences between RNA populations in two conditions, both in production and abundance. This includes the identification of RNAs produced by multiple genomes within a biological system. For example, RNA produced by pathogens within a host or mobile RNAs in plant graft systems. The mobileRNA package provides methods to pre-process, analyse and visualise the sRNA and mRNA populations based on the premise of mapping reads to all genotypes at the same time.

scRecover is an R package for imputation of single-cell RNA-seq (scRNA-seq) data. It will detect and impute dropout values in a scRNA-seq raw read counts matrix while keeping the real zeros unchanged, since there are both dropout zeros and real zeros in scRNA-seq data. By combination with scImpute, SAVER and MAGIC, scRecover not only detects dropout and real zeros at higher accuracy, but also improve the downstream clustering and visualization results.

Probability surveys often use auxiliary continuous data from administrative records, but the utility of this data is diminished when it is discretized for confidentiality. We provide a set of survey estimators to make full use of information from the discretized variables. See Williams, S.Z., Zou, J., Liu, Y., Si, Y., Galea, S. and Chen, Q. (2024), Improving Survey Inference Using Administrative Records Without Releasing Individual-Level Continuous Data. Statistics in Medicine, 43: 5803-5813. <doi:10.1002/sim.10270> for details.

This package provides a tabular data manipulation, exploration and validation toolkit with a base R-style interface (subset, transform, aggregate, merge, split) and no external computation dependency. Grouping, joins, ordering, filtering, reshaping and delimited-file reading run in a bundled C++ engine that uses multiple threads for the heavier operations. Grouped reducers accumulate in compiled code without materialising intermediate columns, so grouped aggregation and counting allocate close to nothing. Results are returned as an ordinary data frame with a light basetable class.

Every research team have their own script for data management, statistics and most importantly hemodynamic indices. The purpose is to standardize scripts utilized in clinical research. The hemodynamic indices can be used in a long-format dataframe, and add both periods of interest (trigger-periods), and delete artifacts with deleter-files. Transfer function analysis (Claassen et al. (2016) <doi:10.1177/0271678X15626425>) and Mx (Czosnyka et al. (1996) <doi:10.1161/01.str.27.10.1829>) can be calculated using this package.

This package provides a unified toolkit for cointegration testing including Fourier-based cointegration tests (FADL, FEG, FEG2, Tsong) that accommodate smooth structural breaks via flexible Fourier terms, and panel CADF cointegration tests with structural breaks using the Common Correlated Effects (CCE) estimator following Banerjee, Arcabic and Lee (2017) <doi:10.1016/j.econmod.2016.11.004>, Tsong, Lee, Tsai and Hu (2016) <doi:10.1007/s00181-015-1028-6>, and Banerjee and Carrion-i-Silvestre (2025) <doi:10.1080/07350015.2024.2327844>.