Collection of tools to automate the processing of data collected though the IDEA4 method (see Zahm et al. (2018) <doi:10.1051/cagri/2019004> ). Starting from the original data collecting files this packages provides functions to compute IDEA indicators, draw modern and aesthetic plots, and produce a wide range of reporting materials.

This package provides a pipeline to annotate a number of peaks from the IDSL.IPA peaklists using an exhaustive chemical enumeration-based approach. This package can perform elemental composition calculations using the following 15 elements : C, B, Br, Cl, K, S, Si, N, H, As, F, I, Na, O, and P.

Simulate and implement early phase two-stage adaptive dose-finding design for binary and quasi-continuous toxicity endpoints. See Chiuzan et al. (2018) for further reading <DOI:10.1080/19466315.2018.1462727>.

Calculates insulin secretion rates from C-peptide values based on the methods described in Van Cauter et al. (1992) <doi:10.2337/diab.41.3.368>. Includes functions to calculate estimated insulin secretion rates using linear or cubic spline interpolation of c-peptide values (see Eaton et al., 1980 <doi:10.1210/jcem-51-3-520> and Polonsky et al., 1986 <doi:10.1172/JCI112308>) and to calculate estimates of input coefficients (volume of distribution, short half life, long half life, and fraction attributed to short half life) as described by Van Cauter. Although the generated coefficients are specific to insulin secretion, the two-compartment secretion model used here is useful for certain applications beyond insulin.

This package contains functions that allow Bayesian inference on a parameter of some widely-used exponential models. The functions can generate independent samples from the closed-form posterior distribution using the inverse stable prior. Inverse stable is a non-conjugate prior for a parameter of an exponential subclass of discrete and continuous data distributions (e.g. Poisson, exponential, inverse gamma, double exponential (Laplace), half-normal/half-Gaussian, etc.). The prior class provides flexibility in capturing a wide array of prior beliefs (right-skewed and left-skewed) as modulated by a parameter that is bounded in (0,1). The generated samples can be used to simulate the prior and posterior predictive distributions. More details can be found in Cahoy and Sedransk (2019) <doi:10.1007/s42519-018-0027-2>. The package can also be used as a teaching demo for introductory Bayesian courses.

Estimation of joint models for multivariate longitudinal markers (with various distributions available) and survival outcomes (possibly accounting for competing risks) with Integrated Nested Laplace Approximations (INLA). The flexible and user friendly function joint() facilitates the use of the fast and reliable inference technique implemented in the INLA package for joint modeling. More details are given in the help page of the joint() function (accessible via ?joint in the R console) and the vignette associated to the joint() function (accessible via vignette("INLAjoint") in the R console).

Simulation of the random evolution of heterogeneous populations using stochastic Individual-Based Models (IBMs) <doi:10.48550/arXiv.2303.06183>. The package enables users to simulate population evolution, in which individuals are characterized by their age and some characteristics, and the population is modified by different types of events, including births/arrivals, death/exit events, or changes of characteristics. The frequency at which an event can occur to an individual can depend on their age and characteristics, but also on the characteristics of other individuals (interactions). Such models have a wide range of applications. For instance, IBMs can be used for simulating the evolution of a heterogeneous insurance portfolio with selection or for validating mortality forecasts. This package overcomes the limitations of time-consuming IBMs simulations by implementing new efficient algorithms based on thinning methods, which are compiled using the Rcpp package while providing a user-friendly interface.

It performs interlaboratory studies (ILS) to detect those laboratories that provide non-consistent results when comparing to others. It permits to work simultaneously with various testing materials, from standard univariate, and functional data analysis (FDA) perspectives. The univariate approach based on ASTM E691-08 consist of estimating the Mandel's h and k statistics to identify those laboratories that provide more significant different results, testing also the presence of outliers by Cochran and Grubbs tests, Analysis of variance (ANOVA) techniques are provided (F and Tuckey tests) to test differences in means corresponding to different laboratories per each material. Taking into account the functional nature of data retrieved in analytical chemistry, applied physics and engineering (spectra, thermograms, etc.). ILS package provides a FDA approach for finding the Mandel's k and h statistics distribution by smoothing bootstrap resampling.

Boxplots adapted to the happenstance of missing observations where drop-out probabilities can be given by the practitioner or modelled using auxiliary covariates. The paper of "Zhang, Z., Chen, Z., Troendle, J. F. and Zhang, J.(2012) <doi:10.1111/j.1541-0420.2011.01712.x>", proposes estimators of marginal quantiles based on the Inverse Probability Weighting method.

Multi-data type subtyping, which is data type agnostic and accepts missing data. Subtyping is performed using intermediary assessments created with autoencoders and similarity calculations.

Generates random numbers corresponding to the events on a Poisson point process with changing event rates. This includes the possibility to incorporate additional information such as the number of events occurring or the location of an already known event. It can also generate the probability density functions of specific events in the cases where additional information is available. Based on Hohmann (2019) <arXiv:1901.10754>.

This package implements the Information Matrix test for regression models following Cameron, A. C., & Trivedi, P. K. (1990) <https://cameron.econ.ucdavis.edu/research/imtest_impliedalternatives_ucdwp372.pdf> Decomposes the test into components for heteroscedasticity, skewness, and kurtosis to diagnose specific forms of misspecification. Provides both overall and component-wise statistics for model assessment.

Simple plotting function(s) for exploratory data analysis with flexible options allowing for easy plot customisation. The goal is to make it easy for beginners to start exploring a dataset through simple R function calls, as well as provide a similar interface to summary statistics and inference information. Includes functionality to generate interactive HTML-driven graphs. Used by iNZight', a graphical user interface providing easy exploration and visualisation of data for students of statistics, available in both desktop and online versions.

The initial basic feasible solution (IBFS) is a significant step to achieve the minimal total cost (optimal solution) of the transportation problem. However, the existing methods of IBFS do not always provide a good feasible solution which can reduce the number of iterations to find the optimal solution. This initial basic feasible solution can be obtained by using any of the following methods. a) North West Corner Method. b) Least Cost Method. c) Row Minimum Method. d) Column Minimum Method. e) Vogel's Approximation Method. etc. For more technical details about the algorithms please refer below URLs. <https://theintactone.com/2018/05/24/ds-u2-topic-8-transportation-problems-initial-basic-feasible-solution/>. <https://www.brainkart.com/article/Methods-of-finding-initial-Basic-Feasible-Solutions_39037/>. <https://myhomeworkhelp.com/row-minima-method/>. <https://myhomeworkhelp.com/column-minima-method/>.

This package provides functions to calculate indices used to score immunoglobulin A (IgA) binding of bacteria in IgA sequencing (IgA-Seq) experiments. This includes the original Kau and Palm indices and more recent methods as described in Jackson et al. (2020) <doi:10.1101/2020.08.19.257501>. Additionally the package contains a function to simulate IgA-Seq data and an example experimental data set for method testing.

This package provides a collection of useful functions and datasets for the Data Science Course at IBAW.

Calculates various chance-corrected agreement coefficients (CAC) among 2 or more raters are provided. Among the CAC coefficients covered are Cohen's kappa, Conger's kappa, Fleiss kappa, Brennan-Prediger coefficient, Gwet's AC1/AC2 coefficients, and Krippendorff's alpha. Multiple sets of weights are proposed for computing weighted analyses. All of these statistical procedures are described in details in Gwet, K.L. (2014,ISBN:978-0970806284): "Handbook of Inter-Rater Reliability," 4th edition, Advanced Analytics, LLC.

Compute permutation- based performance measures and create partial dependence plots for (cross-validated) randomForest and ada models.

This package provides examples of code for analyzing data or accomplishing tasks that may be useful to institutional or educational researchers.

Automates the identification and comparative evaluation of item-removal strategies in exploratory factor analysis, producing transparent summaries (explained variance, loading ranges, reliability) to support comfortable, reproducible decisions. The criteria are based on best practices and established heuristics (e.g., Costello & Osborne (2005) <doi:10.7275/jyj1-4868>, Howard (2016) <doi:10.1080/10447318.2015.1087664>).

Some tools to assist with converting International Organization for Standardization (ISO) standard 11784 (ISO11784) animal ID codes between 4 recognised formats commonly displayed on Passive Integrated Transponder (PIT) tag readers. The most common formats are 15 digit decimal, e.g., 999123456789012, and 13 character hexadecimal dot format, e.g., 3E7.1CBE991A14. These are referred to in this package as isodecimal and isodothex. The other two formats are the raw hexadecimal representation of the ISO11784 binary structure (see <https://en.wikipedia.org/wiki/ISO_11784_and_ISO_11785>). There are two flavours of this format, a left and a right variation. Which flavour a reader happens to output depends on if the developers decided to reverse the binary number or not before converting to hexadecimal, a decision based on the fact that the PIT tags will transmit their binary code Least Significant Bit (LSB) first, or backwards basically.

We provide the collection of data-sets used in the book An Introduction to Statistical Learning with Applications in R'.

Implementation of the methodology proposed in Data-driven design of targeted gene panels for estimating immunotherapy biomarkers', Bradley and Cannings (2021) <arXiv:2102.04296>. This package allows the user to fit generative models of mutation from an annotated mutation dataset, and then further to produce tunable linear estimators of exome-wide biomarkers. It also contains functions to simulate mutation annotated format (MAF) data, as well as to analyse the output and performance of models.

Time series plain text conversion and data visualization. It allows to transform IDEAM (Instituto de Hidrologia, Meteorologia y Estudios Ambientales) daily series from plain text to CSV files or data frames in R. Additionally, it is possible to obtain exploratory graphs from times series. IDEAMâ s data is freely delivered under formal request through the official web page <http://www.ideam.gov.co/solicitud-de-informacion>.