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Two papers published in the early 2000's (Zeeberg, B.R., Feng, W., Wang, G. et al. (2003) <doi:10.1186/gb-2003-4-4-r28>) and (Zeeberg, B.R., Qin, H., Narashimhan, S., et al. (2005) <doi:10.1186/1471-2105-6-168>) implement GoMiner and High Throughput GoMiner ('HTGM') to map lists of genes to the Gene Ontology (GO) <https://geneontology.org>. Until recently, these were hosted on a server at The National Cancer Institute (NCI). In order to continue providing these services to the bio-medical community, I have developed stand-alone versions. The current package HTGM builds upon my recent package GoMiner'. The output of GoMiner is a heatmap showing the relationship of a single list of genes and the significant categories into which they map. High Throughput GoMiner ('HTGM') integrates the results of the individual GoMiner analyses. The output of HTGM is a heatmap showing the relationship of the significant categories derived from each gene list. The heatmap has only 2 axes, so the identity of the genes are unfortunately "integrated out of the equation." Because the graphic for the heatmap is implemented in Scalable Vector Graphics (SVG) technology, it is relatively easy to hyperlink each picture element to the relevant list of genes. By clicking on the desired picture element, the user can recover the "lost" genes.
Hospital data analysis workflow tools, modeling, and automations. This library provides many useful tools to review common administrative hospital data. Some of these include average length of stay, readmission rates, average net pay amounts by service lines just to name a few. The aim is to provide a simple and consistent verb framework that takes the guesswork out of everything.
S3 functions for management, analysis, interpolation and plotting of time series used in hydrology and related environmental sciences. In particular, this package is highly oriented to hydrological modelling tasks. The focus of this package has been put in providing a collection of tools useful for the daily work of hydrologists (although an effort was made to optimise each function as much as possible, functionality has had priority over speed). Bugs / comments / questions / collaboration of any kind are very welcomed, and in particular, datasets that can be included in this package for academic purposes.
This package provides a protocol that facilitates the processing and analysis of Hydrogen-Deuterium Exchange Mass Spectrometry data using p-value statistics and Critical Interval analysis. It provides a pipeline for analyzing data from HDXExaminer (Sierra Analytics, Trajan Scientific), automating matching and comparison of protein states through Welch's T-test and the Critical Interval statistical framework. Additionally, it simplifies data export, generates PyMol scripts, and ensures calculations meet publication standards. HDXBoxeR assists in various aspects of hydrogen-deuterium exchange data analysis, including reprocessing data, calculating parameters, identifying significant peptides, generating plots, and facilitating comparison between protein states. For details check papers by Hageman and Weis (2019) <doi:10.1021/acs.analchem.9b01325> and Masson et al. (2019) <doi:10.1038/s41592-019-0459-y>. HDXBoxeR citation: Janowska et al. (2024) <doi:10.1093/bioinformatics/btae479>.
Plot an R package's recursive dependency graph and tabulate the number of unique downstream dependencies added by top-level dependencies. This helps R package developers identify which of their declared dependencies add the most downstream dependencies in order to prioritize them for removal if needed. Uses graph stress minimization adapted from Schoch (2023) <doi:10.21105/joss.05238> and originally reported in Gansner et al. (2004) <doi:10.1007/978-3-540-31843-9_25>.
We present this package for fitting structural equation models using the hierarchical likelihood method. This package allows extended structural equation model, including dynamic structural equation model. We illustrate the use of our packages with well-known data sets. Therefore, this package are able to handle two serious problems inadmissible solution and factor indeterminacy <doi:10.3390/sym13040657>.
Maintenance has been discontinued for this package. It has been superseded by GeneralizedHyperbolic'. GeneralizedHyperbolic includes all the functionality of HyperbolicDist and more and is based on a more rational design. HyperbolicDist provides functions for the hyperbolic and related distributions. Density, distribution and quantile functions and random number generation are provided for the hyperbolic distribution, the generalized hyperbolic distribution, the generalized inverse Gaussian distribution and the skew-Laplace distribution. Additional functionality is provided for the hyperbolic distribution, including fitting of the hyperbolic to data.
Calculate Hopkins statistic to assess the clusterability of data. See Wright (2023) <doi:10.32614/RJ-2022-055>.
The HistData package provides a collection of small data sets that are interesting and important in the history of statistics and data visualization. The goal of the package is to make these available, both for instructional use and for historical research. Some of these present interesting challenges for graphics or analysis in R.
Using Dirichlet-Multinomial distribution to provide several functions for formal hypothesis testing, power and sample size calculations for human microbiome experiments.
Miscellaneous convenience functions and wrapper functions to convert frequencies between Hz, semitones, mel and Bark, to create a matrix of dummy columns from a factor, to determine whether x lies in range [a,b], and to add a bracketed line to an existing plot. This package also contains an example data set of a stratified sample of 80 talkers of Dutch.
Facilitates automated HTML report creation, in particular framed HTML pages and dynamically sortable tables.
Perform statistical writership analysis of scanned handwritten documents. Webpage provided at: <https://github.com/CSAFE-ISU/handwriter>.
Estimation procedures and goodness-of-fit test for several Markov regime switching models and mixtures of bivariate copula models. The goodness-of-fit test is based on a Cramer-von Mises statistic and uses Rosenblatt's transform and parametric bootstrap to estimate the p-value. The proposed methodologies are described in Nasri, Remillard and Thioub (2020) <doi:10.1002/cjs.11534>.
We provide a toolbox to conduct a Bayesian meta-analysis for estimating the current expansion rate of the Universe, called the Hubble constant H0, via time delay cosmography. The input data are Fermat potential difference and time delay estimates. For a robust inference, we assume a Student's t error for these inputs. Given these inputs, the meta-analysis produces posterior samples of the model parameters including the Hubble constant via Metropolis-Hastings within Gibbs. The package provides an option to implement repelling-attracting Metropolis-Hastings within Gibbs in a case where the parameter space has multiple modes.
Penalized regression for generalized linear models for measurement error problems (aka. errors-in-variables). The package contains a version of the lasso (L1-penalization) which corrects for measurement error (Sorensen et al. (2015) <doi:10.5705/ss.2013.180>). It also contains an implementation of the Generalized Matrix Uncertainty Selector, which is a version the (Generalized) Dantzig Selector for the case of measurement error (Sorensen et al. (2018) <doi:10.1080/10618600.2018.1425626>).
Simple tools for converting columns to new data types. Intuitive functions for columns with missing values.
This package provides access to Uber's H3 geospatial indexing system via h3lib <https://CRAN.R-project.org/package=h3lib>. h3r is designed to mimic the H3 Application Programming Interface (API) <https://h3geo.org/docs/api/indexing/>, so that any function in the API is also available in h3r'.
This package provides functionality to download and cache files from Hugging Face Hub <https://huggingface.co/models>. Uses the same caching structure so files can be shared between different client libraries.
The half-weight index gregariousness (HWIG) is an association index used in social network analyses. It extends the half-weight association index (HWI), correcting for level of gregariousness in individuals. It is calculated using group by individual data according to methods described in Godde et al. (2013) <doi:10.1016/j.anbehav.2012.12.010>.
When performing multiple imputations, while 5-10 imputations are sufficient for obtaining point estimates, a larger number of imputations are needed for proper standard error estimates. This package allows you to calculate how many imputations are needed, following the work of von Hippel (2020) <doi:10.1177/0049124117747303>.
This package provides tools for accessing various open data APIs in the Helsinki region in Finland. Current data sources include the Service Map API, Linked Events API, and Helsinki Region Infoshare statistics API.
We provide an R tool for computation and nonparametric plug-in estimation of Highest Density Regions (HDRs) and general level sets in the directional setting. Concretely, circular and spherical HDRs can be reconstructed from a data sample following Saavedra-Nieves and Crujeiras (2021) <doi:10.1007/s11634-021-00457-4>. This library also contains two real datasets in the circular and spherical settings. The first one concerns a problem from animal orientation studies and the second one is related to earthquakes occurrences.
Analysis of plant pathogen pathotype survey data. Functions provided calculate distribution of susceptibilities, distribution of complexities with statistics, pathotype frequency distribution, as well as diversity indices for pathotypes. This package is meant to be a direct replacement for Herrmann, Löwer and Schachtel's (1999) <doi:10.1046/j.1365-3059.1999.00325.x> Habgood-Gilmour Spreadsheet, HaGiS', previously used for pathotype analysis.