This package provides a tool to format R markdown with CSS ids for HTML output. The tool may be most helpful for those using markdown to create reproducible documents. The biggest limitations in formatting is the knowledge of CSS by the document authors.

Calculate Hopkins statistic to assess the clusterability of data. See Wright (2023) <doi:10.32614/RJ-2022-055>.

Simulate and analyze hierarchical composite endpoints. Includes implementation for the kidney hierarchical composite endpoint as defined in Heerspink HL et al (2023) â Development and validation of a new hierarchical composite end point for clinical trials of kidney disease progressionâ (Journal of the American Society of Nephrology 34 (2): 2025â 2038, <doi:10.1681/ASN.0000000000000243>). Win odds, also called Wilcoxon-Mann-Whitney or success odds, is the main analysis method. Other win statistics (win probability, win ratio, net benefit) are also implemented in the univariate case, provided there is no censoring. The win probability analysis is based on the Brunner-Munzel test and uses the DeLong-DeLong-Clarke-Pearson variance estimator, as described by Brunner and Konietschke (2025) in â An unbiased rank-based estimator of the Mannâ Whitney variance including the case of tiesâ (Statistical Papers 66 (1): 20, <doi:10.1007/s00362-024-01635-0>). Includes implementation of a new Wilson-type, compatible confidence interval for the win odds, as proposed by Schüürhuis, Konietschke, Brunner (2025) in â A new approach to the nonparametric Behrensâ Fisher problem with compatible confidence intervals.â (Biometrical Journal 67 (6), <doi:10.1002/bimj.70096>). Stratification and covariate adjustment are performed based on the methodology presented by Koch GG et al. in â Issues for covariance analysis of dichotomous and ordered categorical data from randomized clinical trials and non-parametric strategies for addressing themâ (Statistics in Medicine 17 (15-16): 1863â 92). For a review, see Gasparyan SB et al (2021) â Adjusted win ratio with stratification: Calculation methods and interpretationâ (Statistical Methods in Medical Research 30 (2): 580â 611, <doi:10.1177/0962280220942558>).

This package provides a procedure that fits derivative curves based on a sequence of quotient differences. In a hierarchical setting the package produces estimates of subject-specific and group-specific derivative curves. In a non-hierarchical setting the package produces a single derivative curve.

Translation between experimental null hypotheses, hypothesis matrices, and contrast matrices as used in linear regression models. The package is based on the method described in Schad et al. (2019) <doi:10.1016/j.jml.2019.104038> and Rabe et al. (2020) <doi:10.21105/joss.02134>.

Seed germinates through the physical process of water uptake by dry seed driven by the difference in water potential between the seed and the water. There exists seed-to-seed variability in the base seed water potential. Hence, there is a need for a distribution such that a viable seed with its base seed water potential germinates if and only if the soil water potential is more than the base seed water potential. This package estimates the stress tolerance and uniformity parameters of the seed lot for germination under various temperatures by using the hydro-time model of counts of germinated seeds under various water potentials. The distribution of base seed water potential has been considered to follow Normal, Logistic and Extreme value distribution. The estimated proportion of germinated seeds along with the estimates of stress and uniformity parameters are obtained using a generalised linear model. The significance test of the above parameters for within and between temperatures is also performed in the analysis. Details can be found in Kebreab and Murdoch (1999) <doi:10.1093/jxb/50.334.655> and Bradford (2002) <https://www.jstor.org/stable/4046371>.

High-dimensional matrix factor models have drawn much attention in view of the fact that observations are usually well structured to be an array such as in macroeconomics and finance. In addition, data often exhibit heavy-tails and thus it is also important to develop robust procedures. We aim to address this issue by replacing the least square loss with Huber loss function. We propose two algorithms to do robust factor analysis by considering the Huber loss. One is based on minimizing the Huber loss of the idiosyncratic error's Frobenius norm, which leads to a weighted iterative projection approach to compute and learn the parameters and thereby named as Robust-Matrix-Factor-Analysis (RMFA), see the details in He et al. (2023)<doi:10.1080/07350015.2023.2191676>. The other one is based on minimizing the element-wise Huber loss, which can be solved by an iterative Huber regression algorithm (IHR), see the details in He et al. (2023) <arXiv:2306.03317>. In this package, we also provide the algorithm for alpha-PCA by Chen & Fan (2021) <doi:10.1080/01621459.2021.1970569>, the Projected estimation (PE) method by Yu et al. (2022)<doi:10.1016/j.jeconom.2021.04.001>. In addition, the methods for determining the pair of factor numbers are also given.

Calculate expected relative risk and proportion protected assuming normally distributed log10 transformed antibody dose for a several component vaccine. Uses Hill models for each component which are combined under Bliss independence. See Saul and Fay, 2007 <DOI:10.1371/journal.pone.0000850>.

This package provides a novel decision tree algorithm in the hypothesis testing framework. The algorithm examines the distribution difference between two child nodes over all possible binary partitions. The test statistic of the hypothesis testing is equivalent to the generalized energy distance, which enables the algorithm to be more powerful in detecting the complex structure, not only the mean difference. It is applicable for numeric, nominal, ordinal explanatory variables and the response in general metric space of strong negative type. The algorithm has superior performance compared to other tree models in type I error, power, prediction accuracy, and complexity.

This package implements the simpler and faster heat index, which matches the values of the original 1979 heat index and its 2022 extension for air temperatures above 300 K (27 C, 80 F) and with only minor differences at lower temperatures. Also implements an algorithm for calculating the thermodynamic (and psychrometric) wet-bulb (and ice-bulb) temperature.

Computes the expectation of the number of transmissions and receptions considering a Hop-by-Hop transport model with limited number of retransmissions per packet. It provides the theoretical results shown in Palma et. al.(2016) <DOI:10.1109/TLA.2016.7555237> and also estimated values based on Monte Carlo simulations. It is also possible to consider random data and ACK probabilities.

Ridge regression provide biased estimators of the regression parameters with lower variance. The HDBRR ("High Dimensional Bayesian Ridge Regression") function fits Bayesian Ridge regression without MCMC, this one uses the SVD or QR decomposition for the posterior computation.

Simulate haplotypes through meioses. Allows specification of population parameters.

Convenience date tools for identifying weekends, business days, and Canadian holidays, including R wrappers for the Canada Holidays API <https://canada-holidays.ca/>.

An S4 implementation of Eq. (3) and Eq. (7) by David J. Hand and Robert J. Till (2001) <DOI:10.1023/A:1010920819831>.

This package implements an empirical approach referred to as PeakTrace which uses multiple hydrographs to detect and follow hydropower plant-specific hydropeaking waves at the sub-catchment scale and to describe how hydropeaking flow parameters change along the longitudinal flow path. The method is based on the identification of associated events and uses (linear) regression models to describe translation and retention processes between neighboring hydrographs. Several regression model results are combined to arrive at a power plant-specific model. The approach is proposed and validated in Greimel et al. (2022) <doi:10.1002/rra.3978>. The identification of associated events is based on the event detection implemented in hydropeak'.

This tool identifies hydropeaking events from raw time-series flow record, a rapid flow variation induced by the hourly-adjusted electricity market. The novelty of HEDA is to use vector angle instead of the first-order derivative to detect change points which not only largely improves the computing efficiency but also accounts for the rate of change of the flow variation. More details <doi:10.1016/j.jhydrol.2021.126392>.

Fits Hierarchical Bayesian space-Time models for Gaussian data. Furthermore, its functions have been implemented for analysing the fitting qualities of those models.

Hospital time series data analysis workflow tools, modeling, and automations. This library provides many useful tools to review common administrative time series hospital data. Some of these include average length of stay, and readmission rates. The aim is to provide a simple and consistent verb framework that takes the guesswork out of everything.

Supplement for the book "Handbook of Regression Methods" by D. S. Young. Some datasets used in the book are included and documented. Wrapper functions are included that simplify the examples in the textbook, such as code for constructing a regressogram and expanding ANOVA tables to reflect the total sum of squares.

This package provides functions implementing change point detection methods using the maximum pairwise Bayes factor approach. Additionally, the package includes tools for generating simulated datasets for comparing and evaluating change point detection techniques.

This package implements hierarchically regularized entropy balancing proposed by Xu and Yang (2022) <doi:10.1017/pan.2022.12>. The method adjusts the covariate distributions of the control group to match those of the treatment group. hbal automatically expands the covariate space to include higher order terms and uses cross-validation to select variable penalties for the balancing conditions.

By binding R functions and the Highmaps <https://www.highcharts.com.cn/products/highmaps> chart library, hchinamap package provides a simple way to map China and its provinces. The map of China drawn by this package contains complete Chinese territory, especially the Nine-dotted line, South Tibet, Hong Kong, Macao and Taiwan.

This package implements a structured, reproducible framework for budget impact modelling (BIM) in health technology assessment (HTA), following the ISPOR Task Force guidelines (Sullivan et al. (2014) <doi:10.1016/j.jval.2013.08.2291> and Mauskopf et al. (2007) <doi:10.1111/j.1524-4733.2007.00187.x>). Provides functions for epidemiology-driven population estimation, market share modelling with flexible uptake dynamics, per-patient cost calculation across multiple cost categories, multi-year budget projections, payer perspective analysis, deterministic sensitivity analysis (DSA), and probabilistic sensitivity analysis (PSA) via Monte Carlo simulation. Produces submission-quality outputs including ISPOR-aligned summary tables, scenario comparison tables, per-patient cost breakdowns, tornado diagrams, PSA histograms, and text and HTML reports compatible with NICE, CADTH, and EU-HTA dossier formats. Ships with an interactive shiny dashboard built on bslib for point-and-click model building and exploration.