This package provides an interface to HDFql <https://www.hdfql.com/> and helper functions for reading data from and writing data to HDF5 files. HDFql provides a high-level language for managing HDF5 data that is platform independent. For more information, see the reference manual <https://www.hdfql.com/resources/HDFqlReferenceManual.pdf>.

It is used to construct run sequences with minimum changes for half replicate of two level factorial run order. Experimenter can save time and resources by minimizing the number of changes in levels of individual factor and therefore the total number of changes. It consists of the function minimal_hrtlf(). This technique can be employed to any half replicate of two level factorial run order where the number of factors are greater than two. In Design of Experiments (DOE) theory, two level of a factor can be represented as integers e.g. - 1 for low and 1 for high. User is expected to enter total number of factors to be considered in the experiment. minimal_hrtlf() provides the required run sequences for the input number of factors. The output also gives the number of changes of each factor along with total number of changes in the run sequence. Due to restricted randomization the minimally changed run sequences of half replicate of two level factorial run order will be affected by trend effect. The output also provides the Trend Factor value of the run order. Trend factor value will lies between 0 to 1. Higher the values, lesser the influence of trend effects on the run order.

This package creates styled tables for data presentation. Export to HTML, LaTeX, RTF, Word', Excel', PowerPoint', typst', SVG and PNG. Simple, modern interface to manipulate borders, size, position, captions, colours, text styles and number formatting. Table cells can span multiple rows and/or columns. Includes a huxreg function to create regression tables, and quick_* one-liners to print tables to a new document.

An implementation of high-probability lower bounds for the total variance distance as introduced in Michel & Naef & Meinshausen (2020) <arXiv:2005.06006>. An estimated lower-bound (with high-probability) on the total variation distance between two probability distributions from which samples are observed can be obtained with the function HPLB.

Harriet was Charles Darwin's pet tortoise (possibly). harrietr implements some function to manipulate distance matrices and phylogenetic trees to make it easier to plot with ggplot2 and to manipulate using tidyverse tools.

This package implements Heckman selection models using a Bayesian approach via Stan and compares the performance of normal, Studentâ s t, and contaminated normal distributions in addressing complexities and selection bias (Heeju Lim, Victor E. Lachos, and Victor H. Lachos, Bayesian analysis of flexible Heckman selection models using Hamiltonian Monte Carlo, 2025, under submission).

Computes the ACMIF test and Bonferroni-adjusted p-value of interaction in two-factor studies. Produces corresponding interaction plot and analysis of variance tables and p-values from several other tests of non-additivity.

Pre-made models that can be rapidly tailored to various chemicals and species using chemical-specific in vitro data and physiological information. These tools allow incorporation of chemical toxicokinetics ("TK") and in vitro-in vivo extrapolation ("IVIVE") into bioinformatics, as described by Pearce et al. (2017) (<doi:10.18637/jss.v079.i04>). Chemical-specific in vitro data characterizing toxicokinetics have been obtained from relatively high-throughput experiments. The chemical-independent ("generic") physiologically-based ("PBTK") and empirical (for example, one compartment) "TK" models included here can be parameterized with in vitro data or in silico predictions which are provided for thousands of chemicals, multiple exposure routes, and various species. High throughput toxicokinetics ("HTTK") is the combination of in vitro data and generic models. We establish the expected accuracy of HTTK for chemicals without in vivo data through statistical evaluation of HTTK predictions for chemicals where in vivo data do exist. The models are systems of ordinary differential equations that are developed in MCSim and solved using compiled (C-based) code for speed. A Monte Carlo sampler is included for simulating human biological variability (Ring et al., 2017 <doi:10.1016/j.envint.2017.06.004>) and propagating parameter uncertainty (Wambaugh et al., 2019 <doi:10.1093/toxsci/kfz205>). Empirically calibrated methods are included for predicting tissue:plasma partition coefficients and volume of distribution (Pearce et al., 2017 <doi:10.1007/s10928-017-9548-7>). These functions and data provide a set of tools for using IVIVE to convert concentrations from high-throughput screening experiments (for example, Tox21, ToxCast) to real-world exposures via reverse dosimetry (also known as "RTK") (Wetmore et al., 2015 <doi:10.1093/toxsci/kfv171>).

Empirical value of the Hellinger correlation, a measure of dependence between two continuous random variables. More details can be found in Geenens and Lafaye De Micheaux (2019) <arXiv:1810.10276v4>.

This package provides functions to assess and test for heterogeneity in the utility of a surrogate marker with respect to a baseline covariate using censored (survival data), and to test for heterogeneity across multiple time points. More details are available in Parast et al (2024) <doi:10.1002/sim.10122>.

Display hexagonally binned scatterplots for multi-class data, using coloured triangles to show class proportions.

Perform statistical writership analysis of scanned handwritten documents with a shiny app for handwriter'.

Identification of recombination events, haplotype reconstruction, sire imputation and pedigree reconstruction using half-sib family SNP data.

Create compressed, interactive HTML (Hypertext Markup Language) reports with embedded Python code, custom JS ('JavaScript') and CSS (Cascading Style Sheets), and wrappers for CanvasXpress plots, networks and more. Based on <https://pypi.org/project/py-report-html/>, its sister project.

Structural handling of Finnish identity codes (natural persons and organizations); extract information, check ID validity and diagnostics.

Calculate and visualize Healthy Eating Index (HEI) scores from National Health and Nutrition Examination Survey 24-hour dietary recall data utilizing three methods recommended by the National Cancer Institute (2024) <https://epi.grants.cancer.gov/hei/hei-methods-and-calculations.html#:~:text=To%20use%20the%20simple%20HEI,the%20total%20scores%20across%20individuals.>. Effortlessly analyze HEI scores across different demographic groups and years.

In the framework of Symbolic Data Analysis, a relatively new approach to the statistical analysis of multi-valued data, we consider histogram-valued data, i.e., data described by univariate histograms. The methods and the basic statistics for histogram-valued data are mainly based on the L2 Wasserstein metric between distributions, i.e., the Euclidean metric between quantile functions. The package contains unsupervised classification techniques, least square regression and tools for histogram-valued data and for histogram time series. An introducing paper is Irpino A. Verde R. (2015) <doi: 10.1007/s11634-014-0176-4>.

EQ-5D value set estimation can be done using the hybrid model likelihood as described by Oppe and van Hout (2010) <doi:10.1002/hec.3560> and Ramos-Goñi et al. (2017) <doi:10.1097/MLR.0000000000000283>. The package is based on flexmix and among others contains an M-step-driver as described by Leisch (2004) <doi:10.18637/jss.v011.i08>. Users can estimate latent classes and address preference heterogeneity. Both uncensored and censored data are supported. Furthermore, heteroscedasticity can be taken into account. It is possible to control for different covariates on the continuous and dichotomous parts of the data and start values can differ between the expected latent classes.

The classical Markowitz's mean-variance portfolio formulation ignores heavy tails and skewness. High-order portfolios use higher order moments to better characterize the return distribution. Different formulations and fast algorithms are proposed for high-order portfolios based on the mean, variance, skewness, and kurtosis. The package is based on the papers: R. Zhou and D. P. Palomar (2021). "Solving High-Order Portfolios via Successive Convex Approximation Algorithms." <arXiv:2008.00863>. X. Wang, R. Zhou, J. Ying, and D. P. Palomar (2022). "Efficient and Scalable High-Order Portfolios Design via Parametric Skew-t Distribution." <arXiv:2206.02412>.

Functions, data sets, analyses and examples from the second edition of the book A Handbook of Statistical Analyses Using R (Brian S. Everitt and Torsten Hothorn, Chapman & Hall/CRC, 2008). The first chapter of the book, which is entitled An Introduction to R'', is completely included in this package, for all other chapters, a vignette containing all data analyses is available. In addition, the package contains Sweave code for producing slides for selected chapters (see HSAUR2/inst/slides).

This package provides easy access to essential climate change datasets to non-climate experts. Users can download the latest raw data from authoritative sources and view it via pre-defined ggplot2 charts. Datasets include atmospheric CO2, methane, emissions, instrumental and proxy temperature records, sea levels, Arctic/Antarctic sea-ice, Hurricanes, and Paleoclimate data. Sources include: NOAA Mauna Loa Laboratory <https://gml.noaa.gov/ccgg/trends/data.html>, Global Carbon Project <https://www.globalcarbonproject.org/carbonbudget/>, NASA GISTEMP <https://data.giss.nasa.gov/gistemp/>, National Snow and Sea Ice Data Center <https://nsidc.org/home>, CSIRO <https://research.csiro.au/slrwavescoast/sea-level/measurements-and-data/sea-level-data/>, NOAA Laboratory for Satellite Altimetry <https://www.star.nesdis.noaa.gov/socd/lsa/SeaLevelRise/> and HURDAT Atlantic Hurricane Database <https://www.aoml.noaa.gov/hrd/hurdat/Data_Storm.html>, Vostok Paleo carbon dioxide and temperature data: <doi:10.3334/CDIAC/ATG.009>.

Method and tool for generating hybrid time series forecasts using an error remodeling approach. These forecasting approaches utilize a recursive technique for modeling the linearity of the series using a linear method (e.g., ARIMA, Theta, etc.) and then models (forecasts) the residuals of the linear forecaster using non-linear neural networks (e.g., ANN, ARNN, etc.). The hybrid architectures comprise three steps: firstly, the linear patterns of the series are forecasted which are followed by an error re-modeling step, and finally, the forecasts from both the steps are combined to produce the final output. This method additionally provides the confidence intervals as needed. Ten different models can be implemented using this package. This package generates different types of hybrid error correction models for time series forecasting based on the algorithms by Zhang. (2003), Chakraborty et al. (2019), Chakraborty et al. (2020), Bhattacharyya et al. (2021), Chakraborty et al. (2022), and Bhattacharyya et al. (2022) <doi:10.1016/S0925-2312(01)00702-0> <doi:10.1016/j.physa.2019.121266> <doi:10.1016/j.chaos.2020.109850> <doi:10.1109/IJCNN52387.2021.9533747> <doi:10.1007/978-3-030-72834-2_29> <doi:10.1007/s11071-021-07099-3>.

This package implements an empirical approach referred to as PeakTrace which uses multiple hydrographs to detect and follow hydropower plant-specific hydropeaking waves at the sub-catchment scale and to describe how hydropeaking flow parameters change along the longitudinal flow path. The method is based on the identification of associated events and uses (linear) regression models to describe translation and retention processes between neighboring hydrographs. Several regression model results are combined to arrive at a power plant-specific model. The approach is proposed and validated in Greimel et al. (2022) <doi:10.1002/rra.3978>. The identification of associated events is based on the event detection implemented in hydropeak'.

This package provides functions to build and use hexagonal discrete global grids using the Snyder ISEA projection ('Snyder 1992 <doi:10.3138/27H7-8K88-4882-1752>) and the H3 hierarchical hexagonal system ('Uber Technologies). Implements the ISEA discrete global grid system ('Sahr', White and Kimerling 2003 <doi:10.1559/152304003100011090>). Includes a fast C++ core for ISEA projection and aperture quantization, an included H3 v4.4.1 C library for native H3 grid operations, and sf'/'terra'-compatible R wrappers for grid generation and coordinate assignment. Output is compatible with dggridR for interoperability.