It has been shown that both DNA methylation and RNA transcription are linked to chronological age and age related diseases. Several estimators have been developed to predict human aging from DNA level and RNA level. Most of the human transcriptional age predictor are based on microarray data and limited to only a few tissues. To date, transcriptional studies on aging using RNASeq data from different human tissues is limited. The aim of this package is to provide a tool for across-tissue and tissue-specific transcriptional age calculation based on GTEx RNASeq data.

This package provides classes and methods to locate, setup, subset, navigate and iterate file sets, i.e. sets of files located in one or more directories on the file system. The API is designed such that these classes can be extended via inheritance to provide a richer API for special file formats. Moreover, a specific name format is defined such that filenames and directories can be considered to have full names which consists of a name followed by comma-separated tags. This adds additional flexibility to identify file sets and individual files.

The key function get_vintage_data() returns a dataframe and is the window into the Census Bureau API requiring just a dataset name, vintage(year), and vector of variable names for survey estimates/percentages. Other functions assist in searching for available datasets, geographies, group/variable concepts of interest. Also provided are functions to access and layer (via standard piping) displayable geometries for the US, states, counties, blocks/tracts, roads, landmarks, places, and bodies of water. Joining survey data with many of the geometry functions is built-in to produce choropleth maps.

This package implements two functions. One of them reads an Affymetrix CDF and creates a hash table environment containing the location/probe set membership mapping. The other one creates a package that automatically loads that environment.

dvd+rw-tools, mostly known for its command growisofs, is a collection of DVD and Blu-ray Disc burning tools. It requires another program, such as mkisofs, genisoimage, or xorrisofs to create ISO 9660 images.

hiredis-rb is a Ruby extension that wraps hiredis, a minimalist C client for Redis. Both the synchronous connection API and a separate protocol reader are supported. It is primarily intended to speed up parsing multi bulk replies.

Systemu can be used on any platform to return status, stdout, and stderr of any command. Unlike other methods like open3 and popen4 there is no danger of full pipes or threading issues hanging your process or subprocess.

Samovar is a modern framework for building command-line tools and applications. It provides a declarative class-based DSL for building command-line parsers that include automatic documentation generation. It helps you keep your functionality clean and isolated where possible.

The biodbChebi library provides access to the ChEBI Database, using biodb package framework. It allows to retrieve entries by their accession number. Web services can be accessed for searching the database by name, mass or other fields.

scClassify is a multiscale classification framework for single-cell RNA-seq data based on ensemble learning and cell type hierarchies, enabling sample size estimation required for accurate cell type classification and joint classification of cells using multiple references.

This package implements several exact methods for allocating optimal sample sizes when designing stratified samples. These methods are discussed in Wright (2012) <doi:10.1080/00031305.2012.733679> and Wright (2017) <doi:10.1016/j.spl.2017.04.026>.

Simulation of bivariate uniform data with a full range of correlations based on two beta densities and computation of the tetrachoric correlation (correlation of bivariate uniform data) from the phi coefficient (correlation of bivariate binary data) and vice versa.

This package implements variable selection for high dimensional datasets with a binary response variable using the EM algorithm. Both probit and logit models are supported. Also included is a useful function to generate high dimensional data with correlated variables.

Analyze and plot the abundance of different RNA biotypes present in a count matrix, this evaluation can be useful if you want to test different strategies of normalization or analyze a particular biotype in a differential gene expression analysis.

This package contains selected variables from the time series profiles for statistical areas level 2 from the 2006, 2011, and 2016 censuses of population and housing, Australia. Also provides methods for viewing the questions asked for convenience during analysis.

Create descriptive tables for continuous and categorical variables. Apply summary statistics and counting function, with or without a grouping variable, and create beautiful reports using rmarkdown or officer'. You can also compute effect sizes and statistical tests if needed.

This package provides statistical tests and support functions for detecting irregular digit patterns in numerical data. The package includes tools for extracting digits at various locations in a number, tests for repeated values, and (Bayesian) tests of digit distributions.

For an observational study with binary treatment, binary outcome and K strata, implements a d-statistic that uses those strata most insensitive to unmeasured bias in treatment assignment.<doi:10.1093/biomet/asaa032> The package has one function, dstat2x2xk.

Average rating and number of votes reported by IMDb for films and shorts with over 100 votes in 2022. The data are analysed in Chapter 3 of the Book Getting (more out of) Graphics (Antony Unwin, CRC Press 2024).

This package provides robust tests for testing in GLMs, by sign-flipping score contributions. The tests are robust against overdispersion, heteroscedasticity and, in some cases, ignored nuisance variables. See Hemerik, Goeman and Finos (2020) <doi:10.1111/rssb.12369>.

Helper to add insets based on geom_sf() from ggplot2'. This package gives you a drop-in replacement for geom_sf() that supports adding a zoomed inset map without having to create and embed a separate plot.

This package implements delete-d jackknife resampling for robust statistical estimation. The package provides both weighted (HC3-adjusted) and unweighted versions of jackknife estimation, with parallel computation support. Suitable for biomedical research and other fields requiring robust variance estimation.

Based on right or interval censored data, compute the maximum likelihood estimator of a (sub)probability density under the assumption that it is log-concave. For further information see Duembgen, Rufibach and Schuhmacher (2014) <doi:10.1214/14-EJS930>.

Code generator for robust dependency-free Shiny applications in the form of packages. It includes numerous convenience functions to create modules, include utility functions to create common Bootstrap elements, setup a project from the ground-up, and much more.