Clustering of high dimensional data with Hidden Markov Model on Variable Blocks (HMM-VB) fitted via Baum-Welch algorithm. Clustering is performed by the Modal Baum-Welch algorithm (MBW), which finds modes of the density function. Lin Lin and Jia Li (2017) <https://jmlr.org/papers/v18/16-342.html>.

It performs maximum likelihood estimation for the Heckman selection model (Normal, Student-t or Contaminated normal) using an EM-algorithm <doi:10.1016/j.jmva.2021.104737>. It also performs influence diagnostic through global and local influence for four possible perturbation schema.

The haversine is a function used to calculate the distance between a pair of latitude and longitude points while accounting for the assumption that the points are on a spherical globe. This package provides a fast, dataframe compatible, haversine function. For the first publication on the haversine calculation see Joseph de Mendoza y RÃ os (1795) <https://books.google.cat/books?id=030t0OqlX2AC> (In Spanish).

This package provides the posterior estimates of the regression coefficients when horseshoe prior is specified. The regression models considered here are logistic model for binary response and log normal accelerated failure time model for right censored survival response. The linear model analysis is also available for completeness. All models provide deviance information criterion and widely applicable information criterion. See <doi:10.1111/rssc.12377> Maity et. al. (2019) <doi:10.1111/biom.13132> Maity et. al. (2020).

Utilities for reading data from the Human Mortality Database (<https://www.mortality.org>), Human Fertility Database (<https://www.humanfertility.org>), and similar databases from the web or locally into an R session as data.frame objects. These are the two most widely used sources of demographic data to study basic demographic change, trends, and develop new demographic methods. Other supported databases at this time include the Human Fertility Collection (<https://www.fertilitydata.org>), The Japanese Mortality Database (<https://www.ipss.go.jp/p-toukei/JMD/index-en.html>), and the Canadian Human Mortality Database (<http://www.bdlc.umontreal.ca/chmd/>). Arguments and data are standardized.

This package provides a lightweight framework for building server-driven web applications in R'. htmxr combines the simplicity of htmx for partial page updates with the power of plumber2 for non-blocking HTTP endpoints. Build interactive dashboards and data applications without writing JavaScript', using familiar R patterns inspired by Shiny'. For more information on htmx', see <https://htmx.org>.

Historical borrowing in clinical trials can improve precision and operating characteristics. This package supports a longitudinal hierarchical model to borrow historical control data from other studies to better characterize the control response of the current study. It also quantifies the amount of borrowing through longitudinal benchmark models (independent and pooled). The hierarchical model approach to historical borrowing is discussed by Viele et al. (2013) <doi:10.1002/pst.1589>.

Offers efficient algorithms for fitting regularization paths for lasso or elastic-net penalized regression models with Huber loss, quantile loss or squared loss. Reference: Congrui Yi and Jian Huang (2017) <doi:10.1080/10618600.2016.1256816>.

The presence of outliers in a dataset can substantially bias the results of statistical analyses. To correct for outliers, micro edits are manually performed on all records. A set of constraints and decision rules is typically used to aid the editing process. However, straightforward decision rules might overlook anomalies arising from disruption of linear relationships. Computationally efficient methods are provided to identify historical, tail, and relational anomalies at the data-entry level (Sartore et al., 2024; <doi:10.6339/24-JDS1136>). A score statistic is developed for each anomaly type, using a distribution-free approach motivated by the Bienaymé-Chebyshev's inequality, and fuzzy logic is used to detect cellwise outliers resulting from different types of anomalies. Each data entry is individually scored and individual scores are combined into a final score to determine anomalous entries. In contrast to fuzzy logic, Bayesian bootstrap and a Bayesian test based on empirical likelihoods are also provided as studied by Sartore et al. (2024; <doi:10.3390/stats7040073>). These algorithms allow for a more nuanced approach to outlier detection, as it can identify outliers at data-entry level which are not obviously distinct from the rest of the data. --- This research was supported in part by the U.S. Department of Agriculture, National Agriculture Statistics Service. The findings and conclusions in this publication are those of the authors and should not be construed to represent any official USDA, or US Government determination or policy.

This package provides functions and datasets to support Smilde, Marini, Westerhuis and Liland (2025, ISBN: 978-1-394-21121-0) "Analysis of Variance for High-Dimensional Data - Applications in Life, Food and Chemical Sciences". This implements and imports a collection of methods for HD-ANOVA data analysis with common interfaces, result- and plotting functions, multiple real data sets and four vignettes covering a range different applications.

Various functions and algorithms are provided here for solving optimal matching tasks in the context of preclinical cancer studies. Further, various helper and plotting functions are provided for unsupervised and supervised machine learning as well as longitudinal mixed-effects modeling of tumor growth response patterns.

Confidence intervals for causal effects, using data collected in different experimental or environmental conditions. Hidden variables can be included in the model with a more experimental version.

Item response theory (IRT) parameter estimation using marginal maximum likelihood and expectation-maximization algorithm (Bock \& Aitkin, 1981 <doi:10.1007/BF02293801>). Within parameter estimation algorithm, several methods for latent distribution estimation are available. Reflecting some features of the true latent distribution, these latent distribution estimation methods can possibly enhance the estimation accuracy and free the normality assumption on the latent distribution.

Analyzing Inductively Coupled Plasma - Mass Spectrometry (ICP-MS) measurement data to evaluate isotope ratios (IRs) is a complex process. The IsoCor package facilitates this process and renders it reproducible by providing a function to run a Shiny'-App locally in any web browser. In this App the user can upload data files of various formats, select ion traces, apply peak detection and perform calculation of IRs and delta values. Results are provided as figures and tables and can be exported. The App, therefore, facilitates data processing of ICP-MS experiments to quickly obtain optimal processing parameters compared to traditional Excel worksheet based approaches. A more detailed description can be found in the corresponding article <doi:10.1039/D2JA00208F>. The most recent version of IsoCor can be tested online at <https://apps.bam.de/shn00/IsoCor/>.

Calculates the RMS intrinsic and parameter-effects curvatures of a nonlinear regression model. The curvatures are global measures of assessing whether a model/data set combination is close-to-linear or not. See Bates and Watts (1980) <doi:10.1002/9780470316757> and Ratkowsky and Reddy (2017) <doi:10.1093/aesa/saw098> for details.

This package provides tools for mapping International Classification of Diseases codes to comorbidity, enabling the identification and analysis of various medical conditions within healthcare data.

This package provides functions to analyse missing value mechanisms and to impute data sets in the context of bottom-up MS-based proteomics.

This package provides a pipeline to annotate a number of peaks from the IDSL.IPA peaklists using an exhaustive chemical enumeration-based approach. This package can perform elemental composition calculations using the following 15 elements : C, B, Br, Cl, K, S, Si, N, H, As, F, I, Na, O, and P.

Sieve semiparametric likelihood methods for analyzing interval-censored failure time data from an outcome-dependent sampling (ODS) design and from a case-cohort design. Zhou, Q., Cai, J., and Zhou, H. (2018) <doi:10.1111/biom.12744>; Zhou, Q., Zhou, H., and Cai, J. (2017) <doi:10.1093/biomet/asw067>.

This package provides a pair of functions for getting and setting the IEEE rounding mode for floating point computations.

Run quality checks on data sets using the same checks that are conducted on the ICES Data Submission Utility (DATSU) <https://datsu.ices.dk>.

Calculate various information criteria in literature for "lm" and "glm" objects.

It provides a generic set of tools for initializing a synthetic population with each individual in specific disease states, and making transitions between those disease states according to the rates calculated on each timestep. The new version 1.0.0 has C++ code integration to make the functions run faster. It has also a higher level function to actually run the transitions for the number of timesteps that users specify. Additional functions will follow for changing attributes on demographic, health belief and movement.

Download and manage data sets of statistical projects and geographic data created by Instituto Nacional de Estadistica y Geografia (INEGI). See <https://www.inegi.org.mx/>.