Analyze small-sample clustered or longitudinal data using modified generalized estimating equations with bias-adjusted covariance estimator. The package provides any combination of three modified generalized estimating equations and 11 bias-adjusted covariance estimators.

This package provides a data visualization design that provides comparison between two (Double) data sources (usually on a par with each other) on one reformed heatmap, while inheriting ggplot2 features.

R provides fantastic tools for changepoint analysis, but plots generated by the tools do not have the ggplot2 style. This tool, however, combines changepoint', changepoint.np and ecp together, and uses ggplot2 to visualize changepoints. It provides a unified ggcpt S3 result class, broom'-style tidy/glance/augment methods, autoplot()', composable geoms ('geom_changepoint()', geom_cpt_segment()', geom_cpt_ci()', stat_changepoint()'), a unified cpt_detect() dispatcher with method introspection via cpt_methods()', wrappers for several optional engines (WBS, WBS2, NOT, MOSUM, FPOP, Isolate-Detect, TGUH), a method comparison module, accuracy metrics, data simulation, and canonical test signals.

An implementation of SPRE (standardised predicted random-effects) statistics in R to explore heterogeneity in genetic association meta- analyses, as described by Magosi et al. (2019) <doi:10.1093/bioinformatics/btz590>. SPRE statistics are precision weighted residuals that indicate the direction and extent with which individual study-effects in a meta-analysis deviate from the average genetic effect. Overly influential positive outliers have the potential to inflate average genetic effects in a meta-analysis whilst negative outliers might lower or change the direction of effect. See the getspres website for documentation and examples <https://magosil86.github.io/getspres/>.

Generic Machine Learning Inference on heterogeneous treatment effects in randomized experiments as proposed in Chernozhukov, Demirer, Duflo and Fernández-Val (2020) <arXiv:1712.04802>. This package's workhorse is the mlr3 framework of Lang et al. (2019) <doi:10.21105/joss.01903>, which enables the specification of a wide variety of machine learners. The main functionality, GenericML(), runs Algorithm 1 in Chernozhukov, Demirer, Duflo and Fernández-Val (2020) <arXiv:1712.04802> for a suite of user-specified machine learners. All steps in the algorithm are customizable via setup functions. Methods for printing and plotting are available for objects returned by GenericML(). Parallel computing is supported.

This package provides functions for drawing scene trees representing scenes that have been drawn using grid graphics.

Graphical tools and goodness-of-fit tests for right-censored data: 1. Kolmogorov-Smirnov, Cramér-von Mises, and Anderson-Darling tests, which use the empirical distribution function for complete data and are extended for right-censored data. 2. Generalized chi-squared-type test, which is based on the squared differences between observed and expected counts using random cells with right-censored data. 3. A series of graphical tools such as probability or cumulative hazard plots to guide the decision about the most suitable parametric model for the data. These functions share several features as they can handle both complete and right-censored data, and they provide parameter estimates for the distributions under study.

Run a Gibbs sampler for a multivariate Bayesian sparse group selection model with Dirac, continuous and hierarchical spike prior for detecting pleiotropy on the traits. This package is designed for summary statistics containing estimated regression coefficients and its estimated covariance matrix. The methodology is available from: Baghfalaki, T., Sugier, P. E., Truong, T., Pettitt, A. N., Mengersen, K., & Liquet, B. (2021) <doi:10.1002/sim.8855>.

This package provides functions to assess the goodness of fit of binary, multinomial and ordinal logistic models. Included are the Hosmer-Lemeshow tests (binary, multinomial and ordinal) and the Lipsitz and Pulkstenis-Robinson tests (ordinal).

Defines classes and methods that can be used to implement genetic algorithms for feature selection. The idea is that we want to select a fixed number of features to combine into a linear classifier that can predict a binary outcome, and can use a genetic algorithm heuristically to select an optimal set of features.

This package provides a system for fitting Gompertz Curve in a Time Series Data.

Comparing two independent or paired groups across a range of descriptive statistics, enabling the evaluation of potential differences in central tendency (mean, median), dispersion (variance, interquartile range), shape (skewness, kurtosis), and distributional characteristics (various quantiles). The analytical framework incorporates parametric t-tests, non-parametric Wilcoxon tests, permutation tests, and bootstrap resampling techniques to assess the statistical significance of observed differences.

Quantitative trait loci mapping and genome wide association analysis are used to find candidate molecular marker or region associated with phenotype based on linkage analysis and linkage disequilibrium. Gene expression quantitative trait loci mapping is used to find candidate molecular marker or region associated with gene expression. In this package, we applied the method in Liu W. (2011) <doi:10.1007/s00122-011-1631-7> and Gusev A. (2016) <doi:10.1038/ng.3506> to genome and transcriptome wide association study, which is aimed at revealing the association relationship between phenotype and molecular markers, expression levels, molecular markers nested within different related expression effect and expression effect nested within different related molecular marker effect. F test based on full and reduced model are performed to obtain p value or likelihood ratio statistic. The best linear model can be obtained by stepwise regression analysis.

Estimating trait heritability and handling overfitting. This package includes a collection of functions for (1) estimating genetic variance-covariances and calculate trait heritability; and (2) handling overfitting by calculating the variance components and the heritability through cross validation.

This package provides ggplot2 equivalents of fixest::coefplot() and fixest::iplot(), for producing nice coefficient plots and interaction plots. Enables some additional functionality and convenience features, including grouped multi-'fixest object faceting and programmatic updates to existing plots (e.g., themes and aesthetics).

An engine to facilitate the orchestration and execution of metadata-driven data management workflows, in compliance with FAIR (Findable, Accessible, Interoperable and Reusable) data management principles. By means of a pivot metadata model, relying on the DublinCore standard (<https://dublincore.org/>), a unique source of metadata can be used to operate multiple and inter-connected data management actions. Users can also customise their own workflows by creating specific actions but the library comes with a set of native actions targeting common geographic information and data management, in particular actions oriented to the publication on the web of metadata and data resources to provide standard discovery and access services. At first, default actions of the library were meant to focus on providing turn-key actions for geospatial (meta)data: 1) by creating manage geospatial (meta)data complying with ISO/TC211 (<https://committee.iso.org/home/tc211>) and OGC (<https://www.ogc.org/standards/>) geographic information standards (eg 19115/19119/19110/19139) and related best practices (eg. INSPIRE'); and 2) by facilitating extraction, reading and publishing of standard geospatial (meta)data within widely used software that compound a Spatial Data Infrastructure ('SDI'), including spatial databases (eg. PostGIS'), metadata catalogues (eg. GeoNetwork', CSW servers), data servers (eg. GeoServer'). The library was then extended to actions for other domains: 1) biodiversity (meta)data standard management including handling of EML metadata, and their management with DataOne servers, 2) in situ sensors, remote sensing and model outputs (meta)data standard management by handling part of CF conventions, NetCDF data format and OPeNDAP access protocol, and their management with Thredds servers, 3) generic / domain agnostic (meta)data standard managers ('DublinCore', DataCite'), to facilitate the publication of data within (meta)data repositories such as Zenodo (<https://zenodo.org>) or DataVerse (<https://dataverse.org/>). The execution of several actions will then allow to cross-reference (meta)data resources in each action performed, offering a way to bind resources between each other (eg. reference Zenodo DOI in GeoNetwork'/'GeoServer metadata, or vice versa reference GeoNetwork'/'GeoServer links in Zenodo or EML metadata). The use of standardized configuration files ('JSON or YAML formats) allow fully reproducible workflows to facilitate the work of data and information managers.

This package provides a ggplot2 extension providing an integrative framework for composable visualization, enabling the creation of complex multi-plot layouts such as insets, circular arrangements, and multi-panel compositions. Built on the grammar of graphics, it offers tools to align, stack, and nest plots, simplifying the construction of richly annotated figures for high-dimensional data contextsâ such as genomics, transcriptomics, and microbiome studiesâ by making it easy to link related plots, overlay clustering results, or highlight shared patterns.

Functional denoising and functional ANOVA through wavelet-domain Markov groves. Fore more details see: Ma L. and Soriano J. (2018) Efficient functional ANOVA through wavelet-domain Markov groves. <arXiv:1602.03990v2 [stat.ME]>.

Identifying spatially variable genes is critical in linking molecular cell functions with tissue phenotypes. This package implemented a granularity-based dimension-agnostic tool for the identification of spatially variable genes. The detailed description of this method is available at Wang, J. and Li, J. et al. 2023 (Wang, J. and Li, J. (2023), <doi:10.1038/s41467-023-43256-5>).

Includes a collection of geographical analysis functions aimed primarily at ecology and conservation science studies, allowing processing of both point and raster data. Now integrates SPECTRE (<https://biodiversityresearch.org/spectre/>), a dataset of global geospatial threat data, developed by the authors.

Dynamically retrieve data from the web to render HTML tables on inspection in R Markdown HTML documents.

This package provides a function built on ggplot2 that visualizes pairwise BLAST alignment results as chord diagrams, intuitively displaying homologous regions between query and subject sequences.

Understanding spatial association is essential for spatial statistical inference, including factor exploration and spatial prediction. Geographically optimal similarity (GOS) model is an effective method for spatial prediction, as described in Yongze Song (2022) <doi:10.1007/s11004-022-10036-8>. GOS was developed based on the geographical similarity principle, as described in Axing Zhu (2018) <doi:10.1080/19475683.2018.1534890>. GOS has advantages in more accurate spatial prediction using fewer samples and critically reduced prediction uncertainty.

Streamline the creation of common charts by taking care of a lot of data preprocessing and plot customization for the user. Provides a high-level interface to create plots using ggplot2'.