RcisTarget identifies transcription factor binding motifs (TFBS) over-represented on a gene list. In a first step, RcisTarget selects DNA motifs that are significantly over-represented in the surroundings of the transcription start site (TSS) of the genes in the gene-set. This is achieved by using a database that contains genome-wide cross-species rankings for each motif. The motifs that are then annotated to TFs and those that have a high Normalized Enrichment Score (NES) are retained. Finally, for each motif and gene-set, RcisTarget predicts the candidate target genes (i.e. genes in the gene-set that are ranked above the leading edge).

This package provides a simple way to manage application settings by loading configuration values from .env or .ini files. It supports default values, type casting, and environment variable overrides, enabling a clean separation of configuration from code. Ideal for managing credentials, API keys, and deployment-specific settings.

R functions for criterion profile analysis, Davison and Davenport (2002) <doi:10.1037/1082-989X.7.4.468> and meta-analytic criterion profile analysis, Wiernik, Wilmot, Davison, and Ones (2020) <doi:10.1037/met0000305>. Sensitivity analyses to aid in interpreting criterion profile analysis results are also included.

This package provides a pair of functions for renaming and encoding data frames using external crosswalk files. It is especially useful when constructing master data sets from multiple smaller data sets that do not name or encode variables consistently across files. Based on similar commands in Stata'.

This package provides a structured profile likelihood algorithm for the logistic fixed effects model and an approximate expectation maximization (EM) algorithm for the logistic mixed effects model. Based on He, K., Kalbfleisch, J.D., Li, Y. and Li, Y. (2013) <doi:10.1007/s10985-013-9264-6>.

Published meta-analyses routinely present one of the measures of heterogeneity introduced in Higgins and Thompson (2002) <doi:10.1002/sim.1186>. For critiquing articles it is often better to convert to another of those measures. Some conversions are provided here and confidence intervals are also available.

Create a kite-square plot for contingency tables using ggplot2', to display their relevant quantities in a single figure (marginal, conditional, expected, observed, chi-squared). The plot resembles a flying kite inside a square if the variables are independent, and deviates from this the more dependence exists.

This package provides an extension to the lolog package by introducing the minTriadicClosure() statistic to capture higher-order interactions among triplets of nodes. This function facilitates improved modelling of group formations and triadic closure in networks. A smoothing parameter has been incorporated to avoid numerical errors.

This package provides functions to facilitate model-based clustering of nodes in a network in a mixture of experts setting, which incorporates covariate information on the nodes in the modelling process. Isobel Claire Gormley and Thomas Brendan Murphy (2010) <doi:10.1016/j.stamet.2010.01.002>.

This package provides flexible dictionary-based cleaning that allows users to specify implicit and explicit missing data, regular expressions for both data and columns, and global matches, while respecting ordering of factors. This package is part of the RECON (<https://www.repidemicsconsortium.org/>) toolkit for outbreak analysis.

Given a network (e.g. a food web), estimates several network indices. These include: Ascendency network indices, Direct and indirect dependencies, Effective measures, Environ network indices, General network indices, Pathway analysis, Network uncertainty indices and constraint efficiencies and the trophic level and omnivory indices of food webs.

This package provides path_chain class and functions, which facilitates loading and saving directory structure in YAML configuration files via config package. The file structure you created during exploration can be transformed into legible section in the config file, and then easily loaded for further usage.

Control Philips Hue smart lighting. Use this package to connect to a Hue bridge on your local network (remote authentication not yet supported) and control your smart lights through the Philips Hue API. All API V1 endpoints are supported. See API documentation at <https://developers.meethue.com/>.

This package provides a set of spatial accessibility measures from a set of locations (demand) to another set of locations (supply). It aims, among others, to support research on spatial accessibility to health care facilities. Includes the locations and some characteristics of major public hospitals in Greece.

Data obtained from surveys contains information not only about the survey responses, but also the survey metadata, e.g. the original survey questions and the answer options. The surveydata package makes it easy to keep track of this metadata, and to easily extract columns with specific questions.

This package provides a diverse collection of U.S. datasets encompassing various fields such as crime, economics, education, finance, energy, healthcare, and more. It serves as a valuable resource for researchers and analysts seeking to perform in-depth analyses and derive insights from U.S.-specific data.

Wavelet decomposition method is very useful for modelling noisy time series data. Wavelet decomposition using haar algorithm has been implemented to developed hybrid Wavelet GBM (Gradient Boosting Method) model for time series forecasting using algorithm by Anjoy and Paul (2017) <DOI:10.1007/s00521-017-3289-9>.

This package provides a Poisson mixture model is implemented to cluster genes from high-throughput transcriptome sequencing (RNA-seq) data. Parameter estimation is performed using either the EM or CEM algorithm, and the slope heuristics are used for model selection (i.e., to choose the number of clusters).

Radon is a Python tool which computes various code metrics. Supported metrics are:

• raw metrics: SLOC, comment lines, blank lines, &c.

• Cyclomatic Complexity (i.e., McCabe’s Complexity)

• Halstead metrics (all of them)

• the Maintainability Index (a Visual Studio metric)

Rossby wave ray paths are traced from a determined source, specified wavenumber, and direction of propagation. "raytracing" also works with a set of experiments changing these parameters, making possible the identification of Rossby wave sources automatically. The theory used here is based on classical studies, such as Hoskins and Karoly (1981) <doi:10.1175/1520-0469(1981)038%3C1179:TSLROA%3E2.0.CO;2>, Karoly (1983) <doi:10.1016/0377-0265(83)90013-1>, Hoskins and Ambrizzi (1993) <doi:10.1175/1520-0469(1993)050%3C1661:RWPOAR%3E2.0.CO;2>, and Yang and Hoskins (1996) <doi:10.1175/1520-0469(1996)053%3C2365:PORWON%3E2.0.CO;2>.

This package plots path diagrams from models in lavaan using the plotting functionality from the DiagrammeR package. DiagrammeR provides nice path diagrams via Graphviz, and these functions make it easy to generate these diagrams from a lavaan path model without having to write the DOT language graph specification.

Convenience functions for aggregating a data frame or data table. Currently mean, sum and variance are supported. For Date variables, the recency and duration are supported. There is also support for dummy variables in predictive contexts. Code has been completely re-written in data.table for computational speed.

This package provides simple assertions with sensible defaults and customisable error messages. It offers convenient assertion call wrappers and a general assert function that can handle any condition. Default error messages are user friendly and easily customized with inline code evaluation and styling powered by the cli package.

This package provides datasets and functions used for analysis and visualizations in the Bayes Rules! book (<https://www.bayesrulesbook.com>). The package contains a set of functions that summarize and plot Bayesian models from some conjugate families and another set of functions for evaluation of some Bayesian models.