Reads in multi-part parquet files. Will read in parquet files that have not been previously coalesced into one file. Convenient for reading in moderately sized, but split files.

This package provides a framework for quality-aware analysis of ground-based phenological data from the PEP725 Pan-European Phenology Database (Templ et al. (2018) <doi:10.1007/s00484-018-1512-8>; Templ et al. (2026) <doi:10.1111/nph.70869>) and similar observation networks. Implements station-level data quality grading, outlier detection, phenological normals (climate baselines), anomaly detection, elevation and latitude gradient estimation with robust regression, spatial synchrony quantification, partial least squares (PLS) regression for identifying temperature-sensitive periods, and sequential Mann-Kendall trend analysis. Supports data import from PEP725 files, conversion of user-supplied data, and downloadable synthetic datasets for teaching without barriers of registration. All analysis outputs provide print', summary', and plot methods. Interactive spatial visualization is available via leaflet'.

This package provides tools for the test for the comparison of survival curves, the evaluation of the goodness-of-fit and the predictive capacity of the proportional hazards model.

This package provides a C++ reimplementation of poLCA - latent class analysis and latent class regression models for polytomous outcome variables, also known as latent structure analysis. It attempts to reproduce results and be as similar as possible to the original code, while running faster, especially with multiple repetitions, by utilising multiple threads. Further reading is available on the Queen Mary, University of London, IT Services Research blog <https://blog.hpc.qmul.ac.uk/speeding_up_r_packages/>.

This package provides tools for analyzing data generated from conjoint survey experiments, a method widely used in the social sciences for studying multidimensional preferences. The package implements estimation of marginal means (MMs) and average marginal component effects (AMCEs), with corrections for measurement error. Methods include profile-level and choice-level estimators, bias correction using intra-respondent reliability (IRR), and visualization utilities. For details on the methodology, see Clayton, Horiuchi, Kaufman, King, and Komisarchik (2025) <https://gking.harvard.edu/conjointE>.

This package provides a suite of statistical tools for post-linkage data analysis (PLDA), designed to account for record linkage errors in downstream modeling. The package implements a familiar, formula-based regression interface that adjusts for linkage uncertainty, accommodating workflows where direct access to unlinked primary files is restricted. It consolidates diverse adjustment methodologies, all of which support generalized linear models (linear, logistic, Poisson, and Gamma). These methodologies include weighting approaches (Chambers (2009) <https://hdl.handle.net/10779/uow.27788247>; Chambers et al. (2023) <doi:10.1002/wics.1596>), mixture modeling (Slawski et al. (2025) <doi:10.1093/jrsssa/qnae083>), and Bayesian mixture modeling (Gutman et al. (2016) <doi:10.1002/sim.6586>). For time-to-event data, both the weighting (Vo et al. (2024) <doi:10.1002/sim.9960>) and mixture modeling approaches accommodate Cox proportional hazards models, while the Bayesian approaches extend to parametric survival analysis. Additionally, the package leverages mixture modeling for contingency table analyses and Bayesian methods to enable the multiple imputation of latent match status.

Interactions between different biological entities are crucial for the function of biological systems. In such networks, nodes represent biological elements, such as genes, proteins and microbes, and their interactions can be defined by edges, which can be either binary or weighted. The dysregulation of these networks can be associated with different clinical conditions such as diseases and response to treatments. However, such variations often occur locally and do not concern the whole network. To capture local variations of such networks, we propose multiplex network differential analysis (MNDA). MNDA allows to quantify the variations in the local neighborhood of each node (e.g. gene) between the two given clinical states, and to test for statistical significance of such variation. Yousefi et al. (2023) <doi:10.1101/2023.01.22.525058>.

This package provides adds postfix and infix logic operators for if, then, unless, and otherwise.

Several functions introduced in Aster et al.'s book on inverse theory. The functions are often translations of MATLAB code developed by the authors to illustrate concepts of inverse theory as applied to geophysics. Generalized inversion, tomographic inversion algorithms (conjugate gradients, ART and SIRT'), non-linear least squares, first and second order Tikhonov regularization, roughness constraints, and procedures for estimating smoothing parameters are included.

Allows to perform the tests of equal predictive accuracy for panels of forecasts. Main references: Qu et al. (2024) <doi:10.1016/j.ijforecast.2023.08.001> and Akgun et al. (2024) <doi:10.1016/j.ijforecast.2023.02.001>.

Assessment for statistically-based PPQ sampling plan, including calculating the passing probability, optimizing the baseline and high performance cutoff points, visualizing the PPQ plan and power dynamically. The analytical idea is based on the simulation methods from the textbook Burdick, R. K., LeBlond, D. J., Pfahler, L. B., Quiroz, J., Sidor, L., Vukovinsky, K., & Zhang, L. (2017). Statistical Methods for CMC Applications. In Statistical Applications for Chemistry, Manufacturing and Controls (CMC) in the Pharmaceutical Industry (pp. 227-250). Springer, Cham.

It provides functions to perform permutation conditional random one-sample and two-samples t-tests in a multivariate framework.

Phylogenetic Diversity (PD, Faith 1992), Evolutionary Distinctiveness (ED, Isaac et al. 2007), Phylogenetic Endemism (PE, Rosauer et al. 2009; Laffan et al. 2016), and Weighted Endemism (WE, Laffan et al. 2016) for presence-absence raster. Faith, D. P. (1992) <doi:10.1016/0006-3207(92)91201-3> Isaac, N. J. et al. (2007) <doi:10.1371/journal.pone.0000296> Laffan, S. W. et al. (2016) <doi:10.1111/2041-210X.12513> Rosauer, D. et al. (2009) <doi:10.1111/j.1365-294X.2009.04311.x>.

Colour palettes for data, based on some well known public data sets. Includes helper functions to map absolute values to known palettes, and capture the work of image colour mapping as raster data sets.

Use phenotype risk scores based on linked clinical and genetic data to study Mendelian disease and rare genetic variants. See Bastarache et al. 2018 <doi:10.1126/science.aal4043>.

Generation of multiple count, binary and continuous variables simultaneously given the marginal characteristics and association structure. Throughout the package, the word Poisson is used to imply count data under the assumption of Poisson distribution. The details of the method are explained in Amatya et al. (2015) <DOI:10.1080/00949655.2014.953534>.

Identifies the entries with patterned responses for psychometric scales. The patterns included in the package are identical (a, a, a), ascending (a, b, c), descending (c, b, a), alternative (a, b, a, b / a, b, c, a, b, c).

R tools for reconstructing paleo food webs from species traits and size rules.

This package produces power spectral density estimates through iterative refinement of the optimal number of sine-tapers at each frequency. This optimization procedure is based on the method of Riedel and Sidorenko (1995), which minimizes the Mean Square Error (sum of variance and bias) at each frequency, but modified for computational stability. The same procedure can now be used to calculate the cross spectrum (multivariate analyses).

In a typical protein labelling procedure, proteins are chemically tagged with a functional group, usually at specific sites, then digested into peptides, which are then analyzed using matrix-assisted laser desorption ionization - time of flight mass spectrometry (MALDI-TOF MS) to generate peptide fingerprint. Relative to the control, peptides that are heavier by the mass of the labelling group are informative for sequence determination. Searching for peptides with such mass shifts, however, can be difficult. This package, designed to tackle this inconvenience, takes as input the mass list of two or multiple MALDI-TOF MS mass lists, and makes pairwise comparisons between the labeled groups vs. control, and restores centroid mass spectra with highlighted peaks of interest for easier visual examination. Particularly, peaks differentiated by the mass of the labelling group are defined as a â pairâ , those with equal masses as a â matchâ , and all the other peaks as a â mismatchâ .For more bioanalytical background information, refer to following publications: Jingjing Deng (2015) <doi:10.1007/978-1-4939-2550-6_19>; Elizabeth Chang (2016) <doi:10.7171/jbt.16-2702-002>.

Generation of multiple count, binary and ordinal variables simultaneously given the marginal characteristics and association structure. Throughout the package, the word Poisson is used to imply count data under the assumption of Poisson distribution. The details of the method are explained in Amatya, A. and Demirtas, H. (2015) <DOI:10.1080/00949655.2014.953534>.

This package provides a comprehensive package for detecting and analyzing causal relationships in complex systems using pattern-based approaches. Key features include state space reconstruction, pattern identification, and causality strength evaluation.

Population dynamic models underpin a range of analyses and applications in ecology and epidemiology. The various approaches for analysing population dynamics models (MPMs, IPMs, ODEs, POMPs, PVA) each require the model to be defined in a different way. This makes it difficult to combine different modelling approaches and data types to solve a given problem. pop aims to provide a flexible and easy to use common interface for constructing population dynamic models and enabling to them to be fitted and analysed in lots of different ways.

These are harmonized datasets produced as part of the Clinical Trials Network (CTN) protocol number 0094. This is a US National Institute of Drug Abuse (NIDA) funded project; to learn more go to <https://ctnlibrary.org/protocol/ctn0094/>. These are datasets which have the data harmonized from CTN-0027 (<https://ctnlibrary.org/protocol/ctn0027/>), CTN-0030 (<https://ctnlibrary.org/protocol/ctn0030/>), and CTN-0051 (<https://ctnlibrary.org/protocol/ctn0051/>).