Efficient calculation of pseudo-ranks and (pseudo)-rank based test statistics. In case of equal sample sizes, pseudo-ranks and mid-ranks are equal. When used for inference mid-ranks may lead to paradoxical results. Pseudo-ranks are in general not affected by such a problem. See Happ et al. (2020, <doi:10.18637/jss.v095.c01>) for details.

For biparental, three and four-way crosses Identity by Descent (IBD) probabilities can be calculated using Hidden Markov Models and inheritance vectors following Lander and Green (<https://www.jstor.org/stable/29713>) and Huang (<doi:10.1073/pnas.1100465108>). One of a series of statistical genetic packages for streamlining the analysis of typical plant breeding experiments developed by Biometris.

This package provides bindings to Tree-sitter', an incremental parsing system for programming tools. Tree-sitter builds concrete syntax trees for source files of any language, and can efficiently update those syntax trees as the source file is edited. It also includes a robust error recovery system that provides useful parse results even in the presence of syntax errors.

Computes confidence intervals for nonlinear functions of model parameters (e.g., product of k coefficients) in single-level and multilevel structural equation models. Methods include the distribution of the product, Monte Carlo simulation, and bootstrap methods. It also performs the Model-Based Constrained Optimization (MBCO) procedure for hypothesis testing of indirect effects. References: Tofighi, D., and MacKinnon, D. P. (2011). RMediation: An R package for mediation analysis confidence intervals. Behavior Research Methods, 43, 692-700. <doi:10.3758/s13428-011-0076-x>; Tofighi, D., and Kelley, K. (2020). Improved inference in mediation analysis: Introducing the model-based constrained optimization procedure. Psychological Methods, 25(4), 496-515. <doi:10.1037/met0000259>; Tofighi, D. (2020). Bootstrap Model-Based Constrained Optimization Tests of Indirect Effects. Frontiers in Psychology, 10, 2989. <doi:10.3389/fpsyg.2019.02989>.

Psupertime is supervised pseudotime for single cell RNAseq data. It uses single cell RNAseq data, where the cells have a known ordering. This ordering helps to identify a small number of genes which place cells in that known order. It can be used for discovery of relevant genes, for identification of subpopulations, and characterization of further unknown or differently labelled data.

Smithay aims to provide building blocks to create wayland compositors in Rust. While not being a full-blown compositor, it'll provide objects and interfaces implementing common functionalities that pretty much any compositor will need, in a generic fashion.

It supports the wayland, wayland-protocols, and some external extensions, such as wlr-protocols and plasma-wayland-protocols.

Smithay aims to provide building blocks to create wayland compositors in Rust. While not being a full-blown compositor, it'll provide objects and interfaces implementing common functionalities that pretty much any compositor will need, in a generic fashion.

It supports the wayland, wayland-protocols, and some external extensions, such as wlr-protocols and plasma-wayland-protocols.

Supplies AnnotationHub with MassBank metabolite/compound annotations bundled in CompDb SQLite databases. CompDb SQLite databases contain general compound annotation as well as fragment spectra representing fragmentation patterns of compounds ions. MassBank data is retrieved from https://massbank.eu/MassBank and processed using helper functions from the CompoundDb Bioconductor package into redistributable SQLite databases.

The package provides statistical tools for detecting differentially abundant proteins in shotgun mass spectrometry-based proteomic experiments with tandem mass tag (TMT) labeling. It provides multiple functionalities, including aata visualization, protein quantification and normalization, and statistical modeling and inference. Furthermore, it is inter-operable with other data processing tools, such as Proteome Discoverer, MaxQuant, OpenMS and SpectroMine.

spatialFDA is a package to calculate spatial statistics metrics. The package takes a SpatialExperiment object and calculates spatial statistics metrics using the package spatstat. Then it compares the resulting functions across samples/conditions using functional additive models as implemented in the package refund. Furthermore, it provides exploratory visualisations using functional principal component analysis, as well implemented in refund.

Estimate group aggregates, where one can set user-defined conditions that each group of records must satisfy to be suitable for aggregation. If a group of records is not suitable, it is expanded using a collapsing scheme defined by the user. A paper on this package was published in the Journal of Statistical Software <doi:10.18637/jss.v112.i04>.

This package contains a range of functions covering the present development of the distributional method for the dichotomisation of continuous outcomes. The method provides estimates with standard error of a comparison of proportions (difference, odds ratio and risk ratio) derived, with similar precision, from a comparison of means. See the URL below or <arXiv:1809.03279> for more information.

Support for geostatistical analysis of multivariate data, in particular data with restrictions, e.g. positive amounts, compositions, distributional data, microstructural data, etc. It includes descriptive analysis and modelling for such data, both from a two-point Gaussian perspective and multipoint perspective. The methods mainly follow Tolosana-Delgado, Mueller and van den Boogaart (2018) <doi:10.1007/s11004-018-9769-3>.

The increasing popularity of geographically weighted (GW) techniques has resulted in the development of several R packages, such as GWmodel'. To facilitate their usages, GWmodelVis provides a shiny'-based interactive visualization toolkit for geographically weighted (GW) models. It includes a number of visualization tools, including dynamic mapping of parameter surfaces, statistical visualization, sonification and exporting videos via FFmpeg'.

This package implements the G-Formula method for causal inference with time-varying treatments and confounders using Bayesian multiple imputation methods, as described by Bartlett et al (2025) <doi:10.1177/09622802251316971>. It creates multiple synthetic imputed datasets under treatment regimes of interest using the mice package. These can then be analysed using rules developed for analysing multiple synthetic datasets.

This package provides a suite of tools for literature-based discovery in biomedical research. Provides functions for retrieving scientific articles from PubMed and other NCBI databases, extracting biomedical entities (diseases, drugs, genes, etc.), building co-occurrence networks, and applying various discovery models including ABC', AnC', LSI', and BITOLA'. The package also includes visualization tools for exploring discovered connections.

Life and Fertility Tables are appropriate to study the dynamics of arthropods populations. This package provides utilities for constructing Life Tables and Fertility Tables, related demographic parameters, and some simple graphs of interest. It also offers functions to transform the obtained data into a known format for better manipulation. In addition, two methods for obtaining the confidence interval are included.

Toolbox and shiny application to help researchers design movement ecology studies, focusing on two key objectives: estimating home range areas, and estimating fine-scale movement behavior, specifically speed and distance traveled. It provides interactive simulations and methodological guidance to support study planning and decision-making. The application is described in Silva et al. (2023) <doi:10.1111/2041-210X.14153>.

Comprehensively identifying states and state-like actors is difficult. This package provides data on states and state-like entities in the international system across time. The package combines and cross-references several existing datasets consistent with the aims and functions of the manydata package. It also includes functions for identifying state references in text, and for generating fictional state names.

Framework for the Item Response Theory analysis of dichotomous and ordinal polytomous outcomes under the assumption of multidimensionality and discreteness of the latent traits. The fitting algorithms allow for missing responses and for different item parameterizations and are based on the Expectation-Maximization paradigm. Individual covariates affecting the class weights may be included in the new version (since 2.1).

Wraps the nametag library <https://github.com/ufal/nametag>, allowing users to find and extract entities (names, persons, locations, addresses, ...) in raw text and build your own entity recognition models. Based on a maximum entropy Markov model which is described in Strakova J., Straka M. and Hajic J. (2013) <https://ufal.mff.cuni.cz/~straka/papers/2013-tsd_ner.pdf>.

Potential outliers are identified for all combinations of a dataset's variables. O3 plots are described in Unwin(2019) <doi:10.1080/10618600.2019.1575226>. The available methods are HDoutliers() from the package HDoutliers', FastPCS() from the package FastPCS', mvBACON() from robustX', adjOutlyingness() from robustbase', DectectDeviatingCells() from cellWise', covMcd() from robustbase'.

This package provides a wrapper for optim for nonlinear regression problems; see Nocedal J and Write S (2006, ISBN: 978-0387-30303-1). Performs ordinary least squares (OLS), iterative re-weighted least squares (IRWLS), and maximum likelihood (MLE). Also includes the robust outlier detection (ROUT) algorithm; see Motulsky, H and Brown, R (2006) <doi:10.1186/1471-2105-7-123>.

Handle data from evolve and resequence experiments. Measured allele frequencies (e.g., from variants called from high-throughput sequencing data) are compared using an update of the PsiSeq algorithm (Earley, Eric and Corbin Jones (2011) <doi:10.1534/genetics.111.129445>). Functions for saving and loading important files are also included, as well as functions for basic data visualization.