Providing C implementation for the computing of monotonic spline bases, including M-splines, I-splines, and C-splines, denoted by MIC splines. The definitions of the spline bases are described in Meyer (2008) <doi: 10.1214/08-AOAS167>. The package also provides the computing of constrained least-squares estimates when a subset of or all of the regression coefficients are constrained to be non-negative.

Using this package, one can determine the minimum sample size required so that the absolute deviation of the sample mean and the population mean of a distribution becomes less than some pre-determined epsilon, i.e. it helps the user to determine the minimum sample size required to attain the pre-fixed precision level by minimizing the difference between the sample mean and population mean.

Analysis functions to quantify inputs importance in neural network models. Functions are available for calculating and plotting the inputs importance and obtaining the activation function of each neuron layer and its derivatives. The importance of a given input is defined as the distribution of the derivatives of the output with respect to that input in each training data point <doi:10.18637/jss.v102.i07>.

This package provides access to the PlanScore Application Programming Interface (<https://github.com/PlanScore/PlanScore/blob/main/API.md>) for scoring redistricting plans. Allows for upload of plans from block assignment files and shape files. For shapes in memory, such as from sf or redist', it processes them to save and upload. Includes tools for tidying responses and saving output from the website.

Power analysis and sample size determination for moderation, mediation, and moderated mediation in models fitted by structural equation modelling using the lavaan package by Rosseel (2012) <doi:10.18637/jss.v048.i02> or by multiple regression. The package manymome by Cheung and Cheung (2024) <doi:10.3758/s13428-023-02224-z> is used to specify the indirect paths or conditional indirect paths to be tested.

Producing the time-dependent receiver operating characteristic (ROC) curve through parametric approaches. Tools for generating random data, fitting, predicting and check goodness of fit are prepared. The methods are developed from the theoretical framework of proportional hazard model and copula functions. Using this package, users can now simulate parametric time-dependent ROC and run experiment to understand the behavior of the curve under different scenario.

An enterprise-targeted scalable and customizable shiny module providing an easy way to incorporate free-form note taking or discussion boards into applications. The package includes a shiny module that can be included in any shiny application to create a panel containing searchable, editable text broken down by section headers. Can be used with a local SQLite database, or a compatible remote database of choice.

Label, recode, rename, and convert datasets and ASCII files more efficiently. speedycode automates the code necessary for labeling variables with the labelled package, recoding and renaming variables with dplyr syntax, and converting ASCII files with the readroper package. Most functions require only the name of the dataset and the code will be automatically written. Some convenience functions useful for converting ASCII files are also included.

This package provides a dynamic model of the big-picture, whole ecosystem effects of hydrodynamics, temperature, nutrients, and fishing on continental shelf marine food webs. The package is described in: Heath, M.R., Speirs, D.C., Thurlbeck, I. and Wilson, R.J. (2020) <doi:10.1111/2041-210X.13510> StrathE2E2: An R package for modelling the dynamics of marine food webs and fisheries. 8pp.

This package provides a clinically meaningful measures of treatment effects for right-censored data are provided, based on the concept of Kendall's tau, along with the corresponding inference procedures. Two plots of tau processes, with the option to account for the cure fraction or not, are available. The plots of tau processes serve as useful graphical tools for monitoring the relative performances over time.

Vasicek density, cumulative distribution, quantile functions and random deviate generation of Vasicek distribution. In addition, there are two functions for fitting the Generalized Additive Models for Location Scale and Shape introduced by Rigby and Stasinopoulos (2005, <doi:10.1111/j.1467-9876.2005.00510.x>). Some functions are written in C++ using Rcpp', developed by Eddelbuettel and Francois (2011, <doi:10.18637/jss.v040.i08>).

This package predicts a drug’s primary target(s) or secondary target(s) by integrating large-scale genetic and drug screens from the Cancer Dependency Map project run by the Broad Institute. It further investigates whether the drug specifically targets the wild-type or mutated target forms. To show how to use this package in practice, we provided sample data along with step-by-step example.

Provide functions for retrieving, exploratory analyzing and visualizing the Human Protein Atlas data. HPAanalyze is designed to fullfill 3 main tasks: (1) Import, subsetting and export downloadable datasets; (2) Visualization of downloadable datasets for exploratory analysis; and (3) Working with the individual XML files. This package aims to serve researchers with little programming experience, but also allow power users to use the imported data as desired.

Modular package for generation of sets of ranges representing the null hypothesis. These can take the form of bootstrap samples of ranges (using the block bootstrap framework of Bickel et al 2010), or sets of control ranges that are matched across one or more covariates. nullranges is designed to be inter-operable with other packages for analysis of genomic overlap enrichment, including the plyranges Bioconductor package.

This package provides a tool to search and download a collection of tumour microenvironment single-cell RNA sequencing datasets and their metadata. TMExplorer aims to act as a single point of entry for users looking to study the tumour microenvironment at the single cell level. Users can quickly search available datasets using the metadata table and then download the ones they are interested in for analysis.

This package provides a comprehensive package for visualizing multi-set intersections and extracting detailed subset information. VennDetail generates high-resolution visualizations including traditional Venn diagrams, Venn-pie plots, and UpSet-style plots. It provides functions to extract and combine subset details with user datasets in various formats. The package is particularly useful for bioinformatics applications but can be used for any multi-set analysis.

This package provides arithmetic functions for R matrix and big.matrix objects as well as functions for QR factorization, Cholesky factorization, General eigenvalue, and Singular value decomposition (SVD). A method matrix multiplication and an arithmetic method -for matrix addition, matrix difference- allows for mixed type operation -a matrix class object and a big.matrix class object- and pure type operation for two big.matrix class objects.

The binomialRF is a new feature selection technique for decision trees that aims at providing an alternative approach to identify significant feature subsets using binomial distributional assumptions (Rachid Zaim, S., et al. (2019)) <doi:10.1101/681973>. Treating each splitting variable selection as a set of exchangeable correlated Bernoulli trials, binomialRF then tests whether a feature is selected more often than by random chance.

Clustering methods, which (if asked) can provide step-by-step explanations of the algorithms used, as described in Ezugwu et. al., (2022) <doi:10.1016/j.engappai.2022.104743>; and datasets to test them on, which highlight the strengths and weaknesses of each technique, as presented in the clustering section of scikit-learn (Pedregosa et al., 2011) <https://jmlr.csail.mit.edu/papers/v12/pedregosa11a.html>.

This package provides functions for calculating the OPTICS Cordillera. The OPTICS Cordillera measures the amount of clusteredness in a numeric data matrix within a distance-density based framework for a given minimum number of points comprising a cluster, as described in Rusch, Hornik, Mair (2018) <doi:10.1080/10618600.2017.1349664>. We provide an R native version with methods for printing, summarizing, and plotting the result.

The purpose of this package is to estimate the potential of urban agriculture to contribute to addressing several urban challenges at the city-scale. Within this aim, we selected 8 indicators directly related to one or several urban challenges. Also, a function is provided to compute new scenarios of urban agriculture. Methods are described by Pueyo-Ros, Comas & Corominas (2023) <doi:10.12688/openreseurope.16054.1>.

This package implements parsimonious hidden Markov models for four-way data via expectation- conditional maximization algorithm, as described in Tomarchio et al. (2020) <arXiv:2107.04330>. The matrix-variate normal distribution is used as emission distribution. For each hidden state, parsimony is reached via the eigen-decomposition of the covariance matrices of the emission distribution. This produces a family of 98 parsimonious hidden Markov models.

This package provides a web application for displaying, analysing and forecasting univariate time series. Includes basic methods such as mean, naïve, seasonal naïve and drift, as well as more complex methods such as Holt-Winters Box,G and Jenkins, G (1976) <doi:10.1111/jtsa.12194> and ARIMA Brockwell, P.J. and R.A.Davis (1991) <doi:10.1007/978-1-4419-0320-4>.

Wrapper functions that interface with Freesurfer <https://surfer.nmr.mgh.harvard.edu/>, a powerful and commonly-used neuroimaging software, using system commands. The goal is to be able to interface with Freesurfer completely in R, where you pass R objects of class nifti', implemented by package oro.nifti', and the function executes an Freesurfer command and returns an R object of class nifti or necessary output.