This package provides a spatiotemporal model that simulates the spread of Ascochyta blight in chickpea fields based on location-specific weather conditions. This model is adapted from a model developed by Diggle et al. (2002) <doi:10.1094/PHYTO.2002.92.10.1110> for simulating the spread of anthracnose in a lupin field.

Fits smoothing spline regression models using scalable algorithms designed for large samples. Seven marginal spline types are supported: linear, cubic, different cubic, cubic periodic, cubic thin-plate, ordinal, and nominal. Random effects and parametric effects are also supported. Response can be Gaussian or non-Gaussian: Binomial, Poisson, Gamma, Inverse Gaussian, or Negative Binomial.

This package implements the framework introduced in Di Francesco and Mellace (2025) <doi:10.48550/arXiv.2502.11691>, shifting the focus to well-defined and interpretable estimands that quantify how treatment affects the probability distribution over outcome categories. It supports selection-on-observables, instrumental variables, regression discontinuity, and difference-in-differences designs.

Allows the user to implement easily canvas elements within a shiny app or an RMarkdown document. The user can create shapes, images and text elements within the canvas which can also be used as a drawing tool for taking notes. The package relies on the fabricjs JavaScript library. See <http://fabricjs.com/>.

Data from various catalogs of astrophysical gamma-ray sources detected by NASA's Large Area Telescope (The Astrophysical Journal, 697, 1071, 2009 June 1), on board the Fermi gamma-ray satellite. More information on Fermi and its data products is available from the Fermi Science Support Center (http://fermi.gsfc.nasa.gov/ssc/).

This package implements Bayesian spatial and spatiotemporal models that optionally allow for extreme spatial deviations through time. glmmfields uses a predictive process approach with random fields implemented through a multivariate-t distribution instead of the usual multivariate normal. Sampling is conducted with Stan'. References: Anderson and Ward (2019) <doi:10.1002/ecy.2403>.

This package implements the basic financial analysis functions similar to (but not identical to) what is available in most spreadsheet software. This includes finding the IRR and NPV of regularly spaced cash flows and annuities. Bond pricing and YTM calculations are included. In addition, Black Scholes option pricing and Greeks are also provided.

This package provides a nomogram can not be easily applied, because it is difficult to calculate the points or even the survival probability. The package, including a function of nomogramEx(), is to extract the polynomial equations to calculate the points of each variable, and the survival probability corresponding to the total points.

This package provides a model library for nlmixr2'. The models include (and plan to include) pharmacokinetic, pharmacodynamic, and disease models used in pharmacometrics. Where applicable, references for each model are included in the meta-data for each individual model. The package also includes model composition and modification functions to make model updates easier.

It makes an objective Bayesian analysis of the spatial regression model using both the normal (NSR) and student-T (TSR) distributions. The functions provided give prior and posterior objective densities and allow default Bayesian estimation of the model regression parameters. Details can be found in Ordonez et al. (2020) <arXiv:2004.04341>.

This package implements the phinterval vector class for representing time spans that may contain gaps (disjoint intervals) or be empty. This class generalizes the lubridate package's interval class to support vectorized set operations (intersection, union, difference, complement) that always return a valid time span, even when disjoint or empty intervals are created.

Utility functions for the handling, analysis and visualisation of data from portable emissions measurement systems ('PEMS') and other similar mobile activity monitoring devices. The package includes a dedicated pems data class that manages many of the quality control, unit handling and data archiving issues that can hinder efforts to standardise PEMS research.

This package provides functions to manipulate dates and count days for quantitative finance analysis. The quantdates package considers leap, holidays and business days for relevant calendars in a financial context to simplify quantitative finance calculations, consistent with International Swaps and Derivatives Association (ISDA) (2006) <https://www.isda.org/book/2006-isda-definitions/> regulations.

This package provides functions for constructing near-optimal generalized full matching. Generalized full matching is an extension of the original full matching method to situations with more intricate study designs. The package is made with large data sets in mind and derives matches more than an order of magnitude quicker than other methods.

Analysis of spatial relationships between cell types in spatial transcriptomics data. Spatial proximity is a critical factor in cell-cell communication. The package calculates nearest neighbor distances between specified cell types and provides visualization tools to explore spatial patterns. Applications include studying cell-cell interactions, immune microenvironment characterization, and spatial organization of tissues.

Builds regression trees and random forests for longitudinal or functional data using a spline projection method. Implements and extends the work of Yu and Lambert (1999) <doi:10.1080/10618600.1999.10474847>. This method allows trees and forests to be built while considering either level and shape or only shape of response trajectories.

Utilities to support spatial data manipulation, query, sampling and modelling in ecological applications. Functions include models for species population density, spatial smoothing, multivariate separability, point process model for creating pseudo- absences and sub-sampling, Quadrant-based sampling and analysis, auto-logistic modeling, sampling models, cluster optimization, statistical exploratory tools and raster-based metrics.

The algorithm provided in this package generates perfect sample for unimodal or multimodal posteriors. Read Once Coupling From The Past, with Metropolis-Multishift is used to generate a perfect sample for a given posterior density based on the two extreme starting paths, minimum and maximum of the most interest range of the posterior. It uses the monotone random operation of multishift coupler which allows to sandwich all of the state space in one point. It means both Markov Chains starting from the maximum and minimum will be coalesced. The generated sample is independent from the starting points. It is useful for mixture distributions too. The output of this function is a real value as an exact draw from the posterior distribution.

This package provides high level functions for reading Affy .CEL files, phenotypic data, and then computing simple things with it, such as t-tests, fold changes and the like. It makes heavy use of the affy library. It also has some basic scatter plot functions and mechanisms for generating high resolution journal figures.

This package comprises a set of pretrained machine learning models to predict basic immune cell types. This enables to quickly get a first annotation of the cell types present in the dataset without requiring prior knowledge. The package also lets you train using own models to predict new cell types based on specific research needs.

This package provides a model agnostic tool for decomposition of predictions from black boxes. It supports additive attributions and attributions with interactions. The Break Down Table shows contributions of every variable to a final prediction. The Break Down Plot presents variable contributions in a concise graphical way. This package works for classification and regression models.

Pry Doc is a Pry REPL plugin. It provides extended documentation support for the REPL by means of improving the show-doc and show-source commands. With help of the plugin the commands are be able to display the source code and the docs of Ruby methods and classes implemented in C.

Discordant is an R package that identifies pairs of features that correlate differently between phenotypic groups, with application to -omics data sets. Discordant uses a mixture model that “bins” molecular feature pairs based on their type of coexpression or coabbundance. Algorithm is explained further in "Differential Correlation for Sequencing Data"" (Siska et al. 2016).

Taking a set of sequence motifs as PWMs, test a set of sequences for over-representation of these motifs, as well as any positional features within the set of motifs. Enrichment analysis can be undertaken using multiple statistical approaches. The package also contains core functions to prepare data for analysis, and to visualise results.