Perform fast and memory efficient time-weighted averaging of values measured over intervals into new arbitrary intervals. This package is useful in the context of data measured or represented as constant values over intervals on a one-dimensional discrete axis (e.g. time-integrated averages of a curve over defined periods). This package was written specifically to deal with air pollution data recorded or predicted as averages over sampling periods. Data in this format often needs to be shifted to non-aligned periods or averaged up to periods of longer duration (e.g. averaging data measured over sequential non-overlapping periods to calendar years).

This package provides a collection of functions that facilitate computational steps related to advice for fisheries management, according to ICES guidelines. These include methods for calculating reference points and model diagnostics.

This package provides functions to to compute a continuum of information-based measures for quantifying the temporal stability of populations, communities, and ecosystems, as well as their associated synchrony, based on species (or species assemblage) biomass or other key variables. When biodiversity data are available, the package also enables the assessment of the corresponding diversityâ stability relationships. All measures are applicable in both temporal and spatial contexts. The theoretical and methodological background is detailed in Chao et al. (2025) <doi:10.1101/2025.08.20.671203>.

Generate interactive volcano plots for exploring gene expression data. Built with ggplot2', the plots are rendered interactive using ggiraph', enabling users to hover over points to display detailed information or click to trigger custom actions.

The inti package is part of the inkaverse project for developing different procedures and tools used in plant science and experimental designs. The mean aim of the package is to support researchers during the planning of experiments and data collection (tarpuy()), data analysis and graphics (yupana()) , and scientific writing. Learn more about the inkaverse project at <https://inkaverse.com/>.

This package contains several tools to treat imaging flow cytometry data from ImageStream® and FlowSight® cytometers ('Amnis® Cytek®'). Provides an easy and simple way to read and write .fcs, .rif, .cif and .daf files. Information such as masks, features, regions and populations set within these files can be retrieved for each single cell. In addition, raw data such as images stored can also be accessed. Users, may hopefully increase their productivity thanks to dedicated functions to extract, visualize, manipulate and export IFC data. Toy data example can be installed through the IFCdata package of approximately 32 MB, which is available in a drat repository <https://gitdemont.github.io/IFCdata/>. See file COPYRIGHTS and file AUTHORS for a list of copyright holders and authors.

Used in testing if the indirect effect from linear regression mediation analysis is equal to 0. Includes established methods such as the Sobel Test, Joint Significant test (maxP), and tests based off the distribution of the Product or Normal Random Variables. Additionally, this package adds more powerful tests based on Intersection-Union theory. These tests are the S-Test, the ps-test, and the ascending squares test. These new methods are uniformly more powerful than maxP, which is more powerful than Sobel and less anti-conservative than the Product of Normal Random Variables. These methods are explored by Kidd and Lin, (2024) <doi:10.1007/s12561-023-09386-6> and Kidd et al., (2025) <doi:10.1007/s10260-024-00777-7>.

Algorithms and utility functions for indoor positioning using fingerprinting techniques. These functions are designed for manipulation of RSSI (Received Signal Strength Intensity) data sets, estimation of positions,comparison of the performance of different models, and graphical visualization of data. Machine learning algorithms and methods such as k-nearest neighbors or probabilistic fingerprinting are implemented in this package to perform analysis and estimations over RSSI data sets.

We consider studies in which information from error-prone diagnostic tests or self-reports are gathered sequentially to determine the occurrence of a silent event. Using a likelihood-based approach incorporating the proportional hazards assumption, we provide functions to estimate the survival distribution and covariate effects. We also provide functions for power and sample size calculations for this setting. Please refer to Xiangdong Gu, Yunsheng Ma, and Raji Balasubramanian (2015) <doi: 10.1214/15-AOAS810>, Xiangdong Gu and Raji Balasubramanian (2016) <doi: 10.1002/sim.6962>, Xiangdong Gu, Mahlet G Tadesse, Andrea S Foulkes, Yunsheng Ma, and Raji Balasubramanian (2020) <doi: 10.1186/s12911-020-01223-w>.

Assist in the estimation of the Intraclass Correlation Coefficient (ICC) from variance components of a one-way analysis of variance and also estimate the number of individuals or groups necessary to obtain an ICC estimate with a desired confidence interval width.

This package provides a bunch of functions to deal with circular data under order restrictions.

Deconvolution of mixed tumour profiles into normal and cancer for each patient, using the ISOpure algorithm in Quon et al. Genome Medicine, 2013 5:29. Deconvolution requires mixed tumour profiles and a set of unmatched "basis" normal profiles.

This toolbox makes working with oxygen, carbon, and clumped isotope data reproducible and straightforward. Use it to quickly calculate isotope fractionation factors, and apply paleothermometry equations.

Simple plotting function(s) for exploratory data analysis with flexible options allowing for easy plot customisation. The goal is to make it easy for beginners to start exploring a dataset through simple R function calls, as well as provide a similar interface to summary statistics and inference information. Includes functionality to generate interactive HTML-driven graphs. Used by iNZight', a graphical user interface providing easy exploration and visualisation of data for students of statistics, available in both desktop and online versions.

This package contains implementations of the integrative Cox model with uncertain event times proposed by Wang, et al. (2020) <doi:10.1214/19-AOAS1287>, the regularized Cox cure rate model with uncertain event status proposed by Wang, et al. (2023) <doi:10.1007/s12561-023-09374-w>, and other survival analysis routines including the Cox cure rate model proposed by Kuk and Chen (1992) <doi:10.1093/biomet/79.3.531> via an EM algorithm proposed by Sy and Taylor (2000) <doi:10.1111/j.0006-341X.2000.00227.x>, the regularized Cox cure rate model with elastic net penalty following Masud et al. (2018) <doi:10.1177/0962280216677748>.

This package provides a collection of statistical tests for genetic association studies and summary data based Mendelian randomization.

Estimates the density of a spatially distributed animal population sampled with an array of passive detectors, such as traps. Models incorporating distance-dependent detection are fitted by simulation and inverse prediction as proposed by Efford (2004) <doi:10.1111/j.0030-1299.2004.13043.x>.

This package provides a comprehensive suite of tools for managing, processing, and analyzing data from the IFCB. I R FlowCytobot ('iRfcb') supports quality control, geospatial analysis, and preparation of IFCB data for publication in databases like <https://www.gbif.org>, <https://www.obis.org>, <https://emodnet.ec.europa.eu/en>, <https://shark.smhi.se/en/>, and <https://www.ecotaxa.org>. The package integrates with the MATLAB ifcb-analysis tool, which is described in Sosik and Olson (2007) <doi:10.4319/lom.2007.5.204>, and provides features for working with raw, manually classified, and machine learningâ classified image datasets. Key functionalities include image extraction, particle size distribution analysis, taxonomic data handling, and biomass concentration calculations, essential for plankton research.

The marginal treatment effect was introduced by Heckman and Vytlacil (2005) <doi:10.1111/j.1468-0262.2005.00594.x> to provide a choice-theoretic interpretation to instrumental variables models that maintain the monotonicity condition of Imbens and Angrist (1994) <doi:10.2307/2951620>. This interpretation can be used to extrapolate from the compliers to estimate treatment effects for other subpopulations. This package provides a flexible set of methods for conducting this extrapolation. It allows for parametric or nonparametric sieve estimation, and allows the user to maintain shape restrictions such as monotonicity. The package operates in the general framework developed by Mogstad, Santos and Torgovitsky (2018) <doi:10.3982/ECTA15463>, and accommodates either point identification or partial identification (bounds). In the partially identified case, bounds are computed using either linear programming or quadratically constrained quadratic programming. Support for four solvers is provided. Gurobi and the Gurobi R API can be obtained from <http://www.gurobi.com/index>. CPLEX can be obtained from <https://www.ibm.com/analytics/cplex-optimizer>. CPLEX R APIs Rcplex and cplexAPI are available from CRAN. MOSEK and the MOSEK R API can be obtained from <https://www.mosek.com/>. The lp_solve library is freely available from <http://lpsolve.sourceforge.net/5.5/>, and is included when installing its API lpSolveAPI', which is available from CRAN.

This package implements the item based collaborative filtering (IBCF) method for continues phenotypes in the context of plant breeding where data are collected for various traits that were studied in various environments proposed by Montesinos-López et al. (2017) <doi:10.1534/g3.117.300309>.

This package provides functions to assess the strength and statistical significance of the relationship between species occurrence/abundance and groups of sites [De Caceres & Legendre (2009) <doi:10.1890/08-1823.1>]. Also includes functions to measure species niche breadth using resource categories [De Caceres et al. (2011) <doi:10.1111/J.1600-0706.2011.19679.x>].

This package provides a set of functions for the modeling of data derived from the Minidisc Infiltrometer device. It calculates cumulative infiltration and square root of time. Also, it calculates the A parameter based on soil physical properties.

Calculates insulin secretion rates from C-peptide values based on the methods described in Van Cauter et al. (1992) <doi:10.2337/diab.41.3.368>. Includes functions to calculate estimated insulin secretion rates using linear or cubic spline interpolation of c-peptide values (see Eaton et al., 1980 <doi:10.1210/jcem-51-3-520> and Polonsky et al., 1986 <doi:10.1172/JCI112308>) and to calculate estimates of input coefficients (volume of distribution, short half life, long half life, and fraction attributed to short half life) as described by Van Cauter. Although the generated coefficients are specific to insulin secretion, the two-compartment secretion model used here is useful for certain applications beyond insulin.

This package performs valid statistical inference on predicted data (IPD) using recent methods, where for a subset of the data, the outcomes have been predicted by an algorithm. Provides a wrapper function with specified defaults for the type of model and method to be used for estimation and inference. Further provides methods for tidying and summarizing results. Salerno et al., (2024) <doi:10.48550/arXiv.2410.09665>.