R data pipelines commonly require reading and writing data to versioned directories. Each directory might correspond to one step of a multi-step process, where that version corresponds to particular settings for that step and a chain of previous steps that each have their own versions. This package creates a configuration object that makes it easy to read and write versioned data, based on YAML configuration files loaded and saved to each versioned folder.

This package unifies access to Statistal Modeling of Omics Data. Across linear modeling engines (lm, lme, lmer, limma, and wilcoxon). Across coding systems (treatment, difference, deviation, etc). Across model formulae (with/without intercept, random effect, interaction or nesting). Across omics platforms (microarray, rnaseq, msproteomics, affinity proteomics, metabolomics). Across projection methods (pca, pls, sma, lda, spls, opls). Across clustering methods (hclust, pam, cmeans). Across survival methods (coxph, survdiff, coin). It provides a fast enrichment analysis implementation.

This R package provides an R Shiny application that enables the user to generate, manage, and edit data and metadata files suitable for the import in cBioPortal for Cancer Genomics. Create cancer studies and edit its metadata. Upload mutation data of a patient that will be concatenated to the data_mutation_extended.txt file of the study. Create and edit clinical patient data, sample data, and timeline data. Create custom timeline tracks for patients.

Fits Bayesian nonlinear Ornstein-Uhlenbeck models with cubic drift, stochastic volatility, and Student-t innovations. The package implements hierarchical priors for sector-specific parameters and supports parallel MCMC sampling via Stan'. Model comparison is performed using Pareto Smoothed Importance Sampling Leave-One-Out (PSIS-LOO) cross-validation following Vehtari, Gelman, and Gabry (2017) <doi:10.1007/s11222-016-9696-4>. Prior specifications follow recommendations from Gelman (2006) <doi:10.1214/06-BA117A> for scale parameters.

This package provides a system for extracting news from Chilean media, specifically through Web Scapping from Chilean media. The package allows for news searches using search phrases and date filters, and returns the results in a structured format, ready for analysis. Additionally, it includes functions to clean the extracted data, visualize it, and store it in databases. All of this can be done automatically, facilitating the collection and analysis of relevant information from Chilean media.

Data package for dartR'. Provides data sets to run examples in dartR'. This was necessary due to the size limit imposed by CRAN'. The data in dartR.data is needed to run the examples provided in the dartR functions. All available data sets are either based on actual data (but reduced in size) and/or simulated data sets to allow the fast execution of examples and demonstration of the functions.

Fits engression models for nonlinear distributional regression. Predictors and targets can be univariate or multivariate. Functionality includes estimation of conditional mean, estimation of conditional quantiles, or sampling from the fitted distribution. Training is done full-batch on CPU (the python version offers GPU-accelerated stochastic gradient descent). Based on "Engression: Extrapolation through the lens of distributional regression" by Xinwei Shen and Nicolai Meinshausen (2024) in JRSSB. Also supports classification (experimental). <doi:10.1093/jrsssb/qkae108>.

This package implements the algorithm by Briefs and Bläser (2025) <https://openreview.net/forum?id=8PHOPPH35D>, based on the approach of Gupta and Bläser (2024) <doi:10.1609/aaai.v38i18.30023>. It determines, for a structural causal model (SCM) whose directed edges form a tree, whether each parameter is unidentifiable, 1-identifiable or 2-identifiable (other cases cannot occur), using a randomized algorithm with provable running time O(n^3 log^2 n).

Fits generalized linear models (GLMs) when there is missing data in both the response and categorical covariates. The functions implement likelihood-based methods using the Expectation and Maximization (EM) algorithm and optionally apply Firthâ s bias correction for improved inference. See Pradhan, Nychka, and Bandyopadhyay (2025) <https:>, Maiti and Pradhan (2009) <doi:10.1111/j.1541-0420.2008.01186.x>, Maity, Pradhan, and Das (2019) <doi:10.1080/00031305.2017.1407359> for further methodological details.

Functionalities for calculating the local score and calculating statistical relevance (p-value) to find a local Score in a sequence of given distribution (S. Mercier and J.-J. Daudin (2001) <https://hal.science/hal-00714174/>) ; S. Karlin and S. Altschul (1990) <https://pmc.ncbi.nlm.nih.gov/articles/PMC53667/> ; S. Mercier, D. Cellier and F. Charlot (2003) <https://hal.science/hal-00937529v1/> ; A. Lagnoux, S. Mercier and P. Valois (2017) <doi:10.1093/bioinformatics/btw699> ).

Statistical methods for whole-trial and time-domain analysis of single cell neural response to multiple stimuli presented simultaneously. The package is based on the paper by C Glynn, ST Tokdar, A Zaman, VC Caruso, JT Mohl, SM Willett, and JM Groh (2021) "Analyzing second order stochasticity of neural spiking under stimuli-bundle exposure", is in press for publication by the Annals of Applied Statistics. A preprint may be found at <arXiv:1911.04387>.

Calculation of the parametric, nonparametric confidence intervals for the difference or ratio of location parameters, nonparametric confidence interval for the Behrens-Fisher problem and for the difference, ratio and odds-ratio of binomial proportions for comparison of independent samples. Common wrapper functions to split data sets and apply confidence intervals or tests to these subsets. A by-statement allows calculation of CI separately for the levels of further factors. CI are not adjusted for multiplicity.

Design and analyze two-stage randomized trials with a continuous outcome measure. The package contains functions to compute the required sample size needed to detect a given preference, treatment, and selection effect; alternatively, the package contains functions that can report the study power given a fixed sample size. Finally, analysis functions are provided to test each effect using either summary data (i.e. means, variances) or raw study data <doi:10.18637/jss.v094.c02>.

This package provides functions for performing set-theoretic multi-method research, QCA for clustered data, theory evaluation, Enhanced Standard Analysis, indirect calibration, radar visualisations. Additionally it includes data to replicate the examples in the books by Oana, I.E, C. Q. Schneider, and E. Thomann. Qualitative Comparative Analysis (QCA) using R: A Beginner's Guide. Cambridge University Press and C. Q. Schneider and C. Wagemann "Set Theoretic Methods for the Social Sciences", Cambridge University Press.

This package provides a simple, configurable, provider-agnostic OAuth 2.0 and OpenID Connect (OIDC) authentication framework for shiny applications using S7 classes. Defines providers, clients, and tokens, as well as various supporting functions and a shiny module. Features include cross-site request forgery (CSRF) protection, state encryption, Proof Key for Code Exchange (PKCE) handling, validation of OIDC identity tokens (nonces, signatures, claims), automatic user info retrieval, asynchronous flows, and hooks for audit logging.

Multiscale multifractal analysis (MMA) (GieraÅ towski et al., 2012)<DOI:10.1103/PhysRevE.85.021915> is a time series analysis method, designed to describe scaling properties of fluctuations within the signal analyzed. The main result of this procedure is the so called Hurst surface h(q,s) , which is a dependence of the local Hurst exponent h (fluctuation scaling exponent) on the multifractal parameter q and the scale of observation s (data window width).

ChemmineOB provides an R interface to a subset of cheminformatics functionalities implemented by the OpelBabel C++ project. OpenBabel is a free cheminformatics toolbox that includes utilities for structure format interconversions, descriptor calculations, compound similarity searching and more. ChemineOB aims to make a subset of these utilities available from within R. For non-developers, ChemineOB is primarily intended to be used from ChemmineR as an add-on package rather than used directly.

Implement various chromosomal instability metrics. CINmetrics (Chromosomal INstability metrics) provides functions to calculate various chromosomal instability metrics on masked Copy Number Variation(CNV) data at individual sample level. The chromosomal instability metrics have been implemented as described in the following studies: Baumbusch LO et al. 2013 <doi:10.1371/journal.pone.0054356>, Davidson JM et al. 2014 <doi:10.1371/journal.pone.0079079>, Chin SF et al. 2007 <doi:10.1186/gb-2007-8-10-r215>.

Decorate functions to make them return enhanced output. The enhanced output consists in an object of type chronicle containing the result of the function applied to its arguments, as well as a log detailing when the function was run, what were its inputs, what were the errors (if the function failed to run) and other useful information. Tools to handle decorated functions are included, such as a forward pipe operator that makes chaining decorated functions possible.

Optimal design analysis algorithms for any study design that can be represented or modelled as a generalised linear mixed model including cluster randomised trials, cohort studies, spatial and temporal epidemiological studies, and split-plot designs. See <https://github.com/samuel-watson/glmmrBase/blob/master/README.md> for a detailed manual on model specification. A detailed discussion of the methods in this package can be found in Watson, Hemming, and Girling (2023) <doi:10.1177/09622802231202379>.

Learning and using the Metropolis algorithm for Bayesian fitting of a generalized linear model. The package vignette includes examples of hand-coding a logistic model using several variants of the Metropolis algorithm. The package also contains R functions for simulating posterior distributions of Bayesian generalized linear model parameters using guided, adaptive, guided-adaptive and random walk Metropolis algorithms. The random walk Metropolis algorithm was originally described in Metropolis et al (1953); <doi:10.1063/1.1699114>.

Measures niche breadth and overlap of microbial taxa from large matrices. Niche breadth measurements include Levins niche breadth (Bn) index, Hurlbert's Bn and Feinsinger's proportional similarity (PS) index. (Feinsinger, P., Spears, E.E., Poole, R.W. (1981) <doi:10.2307/1936664>). Niche overlap measurements include Levin's Overlap (Ludwig, J.A. and Reynolds, J.F. (1988, ISBN:0471832359)) and a Jaccard similarity index of Feinsinger's PS values between taxa pairs, as Proportional Overlap.

Find recursive dependencies of R packages from various sources. Solve the dependencies to obtain a consistent set of packages to install. Download packages, and install them. It supports packages on CRAN', Bioconductor and other CRAN-like repositories, GitHub', package URLs', and local package trees and files. It caches metadata and package files via the pkgcache package, and performs all HTTP requests, downloads, builds and installations in parallel. pkgdepends is the workhorse of the pak package.

This package provides tools for estimating model-agnostic prediction intervals using conformal prediction, bootstrapping, and parametric prediction intervals. The package is designed for ease of use, offering intuitive functions for both binned and full conformal prediction methods, as well as parametric interval estimation with diagnostic checks. Currently only working for continuous predictions. For details on the conformal and bin-conditional conformal prediction methods, see Randahl, Williams, and Hegre (2024) <DOI:10.48550/arXiv.2410.14507>.