When the values of the outcome variable Y are either 0 or 1, the function lsm() calculates the estimation of the log likelihood in the saturated model. This model is characterized by Llinas (2006, ISSN:2389-8976) in section 2.3 through the assumptions 1 and 2. The function LogLik() works (almost perfectly) when the number of independent variables K is high, but for small K it calculates wrong values in some cases. For this reason, when Y is dichotomous and the data are grouped in J populations, it is recommended to use the function lsm() because it works very well for all K.

Nonparametric methods for landmark prediction of long-term survival outcomes, incorporating covariate and short-term event information. The package supports the construction of flexible varying-coefficient models that use discrete covariates, as well as multiple continuous covariates. The goal is to improve prediction accuracy when censored short-term events are available as predictors, using robust nonparametric procedures that do not require correct model specification and avoid restrictive parametric assumptions found in alternative methods. More information on these methods can be found in Parast et al. 2012 <doi:10.1080/01621459.2012.721281>, Parast et al. 2011 <doi:10.1002/bimj.201000150>, and Parast and Cai 2013 <doi:10.1002/sim.5776>. A tutorial for this package is available here: <https://www.laylaparast.com/landpred>.

This package creates a consensus genetic map by merging linkage maps from different populations. The software uses linear programming (LP) to efficiently minimize the mean absolute error between the consensus map and the linkage maps. This minimization is performed subject to linear inequality constraints that ensure the ordering of the markers in the linkage maps is preserved. When marker order is inconsistent between linkage maps, a minimum set of ordinal constraints is deleted to resolve the conflicts.

Dataset and functions to explore quality of literary novels. The package is a part of the Riddle of Literary Quality project, and it contains the data of a reader survey about fiction in Dutch, a description of the novels the readers rated, and the results of stylistic measurements of the novels. The package also contains functions to combine, analyze, and visualize these data. For more details, see: Eder M, van Zundert J, Lensink S, van Dalen-Oskam K (2022). Replicating The Riddle of Literary Quality: The litRiddle package for R. In _Digital Humanities 2022: Conference Abstracts_, 636-637.

LINCS L1000 is a high-throughput technology that allows the gene expression measurement in a large number of assays. However, to fit the measurements of ~1000 genes in the ~500 color channels of LINCS L1000, every two landmark genes are designed to share a single channel. Thus, a deconvolution step is required to infer the expression values of each gene. Any errors in this step can be propagated adversely to the downstream analyses. We present a LINCS L1000 data peak calling R package l1kdeconv based on a new outlier detection method and an aggregate Gaussian mixture model. Upon the remove of outliers and the borrowing information among similar samples, l1kdeconv shows more stable and better performance than methods commonly used in LINCS L1000 data deconvolution.

This package produces high resolution, publication ready linkage maps and quantitative trait loci maps. Input can be output from R/qtl', simple text or comma delimited files. Output is currently a portable document file.

Estimates marginal likelihood from a posterior sample using the method described in Wang et al. (2023) <doi:10.1093/sysbio/syad007>, which does not require evaluation of any additional points and requires only the log of the unnormalized posterior density for each sampled parameter vector.

Conducts various numerical analyses and simulations in population genetics and evolutionary theory, primarily for the purpose of teaching (and learning about) key concepts in population & quantitative genetics, and evolutionary theory.

This package provides methods for assessing agreement between repeated measurements obtained by two or more methods using the longitudinal concordance correlation coefficient (LCC). Polynomial mixed-effects models (via nlme') describe how concordance, Pearson correlation and accuracy evolve over time. Functions are provided for model fitting, diagnostic plots, extraction of summaries, and non-parametric bootstrap confidence intervals (including parallel computation), following Oliveira et al. (2018) <doi:10.1007/s13253-018-0321-1>.

Performing impulse-response function (IRF) analysis of relevant variables of agent-based simulation models, in particular for models described in LSD format. Based on the data produced by the simulation model, it performs both linear and state-dependent IRF analysis, providing the tools required by the Counterfactual Monte Carlo (CMC) methodology (Amendola and Pereira (2024) <doi:10.2139/ssrn.4740360>), including state identification and sensitivity. CMC proposes retrieving the causal effect of shocks by exploiting the opportunity to directly observe the counterfactual in a fully controlled experimental setup. LSD (Laboratory for Simulation Development) is free software available at <https://www.labsimdev.org/>).

Computational routines for estimating local Gaussian parameters. Local Gaussian parameters are useful for characterizing and testing for non-linear dependence within bivariate data. See e.g. Tjostheim and Hufthammer, Local Gaussian correlation: A new measure of dependence, Journal of Econometrics, 2013, Volume 172 (1), pages 33-48 <DOI:10.1016/j.jeconom.2012.08.001>.

Latent budget analysis is a method for the analysis of a two-way contingency table with an exploratory variable and a response variable. It is specially designed for compositional data.

Interactive shiny application for working with different kinds of latent variable analysis, with the lavaan package. Graphical output for models are provided and different estimators are supported.

Build complex LaTeX mathematical expressions using intuitive R functions. Replace error-prone LaTeX syntax with readable, modular functions that make mathematical typesetting straightforward and maintainable.

This package implements the letter value boxplot which extends the standard boxplot to deal with both larger and smaller number of data points by dynamically selecting the appropriate number of letter values to display.

This package provides a simple mechanism to specify a symmetric block diagonal matrices (often used for covariance matrices). This is based on the domain specific language implemented in nlmixr2 but expanded to create matrices in R generally instead of specifying parts of matrices to estimate. It has expanded to include some matrix manipulation functions that are generally useful for rxode2 and nlmixr2'.

Generate and correlate synthetic Likert and rating-scale data with predefined means, standard deviations, Cronbach's Alpha, Factor Loading table, coefficients, and other summary statistics. Worked examples and documentation are available in the package articles, accessible via the package website, <https://winzarh.github.io/LikertMakeR/>.

Impute observed values below the limit of detection (LOD) via censored likelihood multiple imputation (CLMI) in single-pollutant models, developed by Boss et al (2019) <doi:10.1097/EDE.0000000000001052>. CLMI handles exposure detection limits that may change throughout the course of exposure assessment. lodi provides functions for imputing and pooling for this method.

This package provides a ggplot2 extension that focusses on expanding the plotter's arsenal of guides. Guides in ggplot2 include axes and legends. legendry offers new axes and annotation options, as well as new legends and colour displays.

This package provides tools for estimation and inference of conditional densities, derivatives and functions. This is the companion software for Cattaneo, Chandak, Jansson and Ma (2024) <doi:10.3150/23-BEJ1711>.

This package provides classes and methods for objects, whose indexing naturally starts from zero. Subsetting, indexing and mathematical operations are defined naturally between lagged objects and lagged and base R objects. Recycling is not used, except for singletons. The single bracket operator doesn't drop dimensions by default.

Fit linear models based on periodic splines, moderate model coefficients using multivariate adaptive shrinkage, then compute properties of the moderated curves.

This package implements Lagrangian multiplier smoothing splines for flexible nonparametric regression and function estimation. Provides tools for fitting, prediction, and inference using a constrained optimization approach to enforce smoothness. Supports generalized linear models, Weibull accelerated failure time (AFT) models, quadratic programming problems, and customizable arbitrary correlation structures. Options for fitting in parallel are provided. The method builds upon the framework described by Ezhov et al. (2018) <doi:10.1515/jag-2017-0029> using Lagrangian multipliers to fit cubic splines. For more information on correlation structure estimation, see Searle et al. (2009) <ISBN:978-0470009598>. For quadratic programming and constrained optimization in general, see Nocedal & Wright (2006) <doi:10.1007/978-0-387-40065-5>. For a comprehensive background on smoothing splines, see Wahba (1990) <doi:10.1137/1.9781611970128> and Wood (2006) <ISBN:978-1584884743> "Generalized Additive Models: An Introduction with R".

Useful shiny production-ready modules and helpers such as login window and visualization tools.