Survival analysis with sparse longitudinal covariates under right censoring scheme. Different hazards models are involved. Please cite the manuscripts corresponding to this package: Sun, Z. et al. (2022) <doi:10.1007/s10985-022-09548-6>, Sun, Z. and Cao, H. (2023) <arXiv:2310.15877> and Sun, D. et al. (2023) <arXiv:2308.15549>.

Load and export SomaScan data via the SomaLogic Operating Co., Inc. structured text file called an ADAT ('*.adat'). For file format see <https://github.com/SomaLogic/SomaLogic-Data/blob/main/README.md>. The package also exports auxiliary functions for manipulating, wrangling, and extracting relevant information from an ADAT object once in memory.

Built on top of the tibble package, tibbletime is an extension that allows for the creation of time aware tibbles. Some immediate advantages of this include: the ability to perform time-based subsetting on tibbles, quickly summarising and aggregating results by time periods, and creating columns that can be used as dplyr time-based groups.

Uses bootstrap to test zero order correlation being equal to a partial or semi-partial correlation (one or two tailed). Confidence intervals for the parameter (zero order minus partial) can also be determined. Implements the bias-corrected and accelerated bootstrap method as described in "An Introduction to the Bootstrap" Efron (1983) <0-412-04231-2>.

Wraps dozens of REDCap API endpoints into a standardized R6 object. Research Electronic Data Capture ('REDCap') is a survey and database web application software maintained by Vanderbilt University. It has a robust application programming interface (API) utilized by several R packages. REDCapSync uses redcapAPI and REDCapR behind-the-scenes to retrieve all metadata, data, and log details for a project. To minimize unnecessary server calls, the interim REDCap log is analyzed and used to only update necessary records. Furthermore, the user can define custom datasets that save to a directory. Those datasets continue to refresh when projects are synced. Having a secure, standardized, API-efficient, project-agnostic R object for REDCap projects, streamlines downstream use in scripts, functions, and shiny applications.

The nls.lm function provides an R interface to lmder and lmdif from the MINPACK library, for solving nonlinear least-squares problems by a modification of the Levenberg-Marquardt algorithm, with support for lower and upper parameter bounds. The implementation can be used via nls-like calls using the nlsLM function.

This package provides S4 classes for general nucleases, CRISPR nucleases, CRISPR nickases, and base editors.Several CRISPR-specific genome arithmetic functions are implemented to help extract genomic coordinates of spacer and protospacer sequences. Commonly-used CRISPR nuclease objects are provided that can be readily used in other packages. Both DNA- and RNA-targeting nucleases are supported.

HMP16SData is a Bioconductor ExperimentData package of the Human Microbiome Project (HMP) 16S rRNA sequencing data for variable regions 1–3 and 3–5. Raw data files are provided in the package as downloaded from the HMP Data Analysis and Coordination Center. Processed data is provided as SummarizedExperiment class objects via ExperimentHub.

ncRNAtools provides a set of basic tools for handling and analyzing non-coding RNAs. These include tools to access the RNAcentral database and to predict and visualize the secondary structure of non-coding RNAs. The package also provides tools to read, write and interconvert the file formats most commonly used for representing such secondary structures.

This package contains a set of functions to perform large-scale analysis of pharmaco-genomic data. These include the PharmacoSet object for storing the results of pharmacogenomic experiments, as well as a number of functions for computing common summaries of drug-dose response and correlating them with the molecular features in a cancer cell-line.

An interface to Azure Queue Storage'. This is a cloud service for storing large numbers of messages, for example from automated sensors, that can be accessed remotely via authenticated calls using HTTP or HTTPS. Queue storage is often used to create a backlog of work to process asynchronously. Part of the AzureR family of packages.

The ggarrow package is a ggplot2 extension that plots a variety of different arrow segments with many options to customize. The arrowheadr package makes it easy to create custom arrowheads and fins within the parameters that ggarrow functions expect. It has preset arrowheads and a collection of functions to create and transform data for customizing arrows.

Inference of protein complex states from quantitative proteomics data. The package takes information on known stable protein interactions (i.e. protein components of the same complex) and assesses how protein quantitative ratios change between different conditions. It reports protein pairs for which relative protein quantities to each other have been significantly altered in the tested condition.

Interface to the Azure Machine Learning Software Development Kit ('SDK'). Data scientists can use the SDK to train, deploy, automate, and manage machine learning models on the Azure Machine Learning service. To learn more about Azure Machine Learning visit the website: <https://docs.microsoft.com/en-us/azure/machine-learning/service/overview-what-is-azure-ml>.

Microsoft Word docx files provide an XML structure that is fairly straightforward to navigate, especially when it applies to Word tables and comments. Tools are provided to determine table count/structure, comment count and also to extract/clean tables and comments from Microsoft Word docx documents. There is also nascent support for .doc and .pptx files.

Enables users to incorporate expert opinion with parametric survival analysis using a Bayesian or frequentist approach. Expert Opinion can be provided on the survival probabilities at certain time-point(s) or for the difference in mean survival between two treatment arms. Please reference it's use as Cooney, P., White, A. (2023) <doi:10.1177/0272989X221150212>.

This package implements three complementary pipelines for causal analysis on macroeconomic time series: (1) Error-Correction Models with Multivariate Adaptive Regression Splines (ECM-MARS), (2) Bayesian Structural Time Series (BSTS), and (3) Bayesian GLM with AR(1) errors validated with Leave-Future-Out (LFO). Heavy backends (Stan) are optional and never used in examples or tests.

This package provides a tidy R interface for count time series analysis. It includes implementation of the INGARCH (Integer Generalized Autoregressive Conditional Heteroskedasticity) model from the tscount package and the GLARMA (Generalized Linear Autoregressive Moving Averages) model from the glarma package. Additionally, it offers automated parameter selection algorithms based on the minimization of a penalized likelihood.

Play or simulate games of "Four in a Row" in the R console. This package is designed for educational purposes, encouraging users to write their own functions to play the game automatically. It contains a collection of built-in functions that play the game at various skill levels, for users to test their own functions against.

Scrapes football match shots data from Understat <https://understat.com/> and visualizes it using interactive plots: - A detailed shot map displaying the location, type, and xG value of shots taken by both teams. - An xG timeline chart showing the cumulative xG for each team over time, annotated with the details of scored goals.

Fit, summarize and plot sinusoidal hysteretic processes using: two-step simple harmonic least squares, ellipse-specific non-linear least squares, the direct method, geometric least squares or linear least squares. See Yang, F and A. Parkhurst, "Efficient Estimation of Elliptical Hysteresis with Application to the Characterization of Heat Stress" <DOI:10.1007/s13253-015-0213-6>.

Generates Rd files from R source code with comments. The main features of the default syntax are that (1) docs are defined in comments near the relevant code, (2) function argument names are not repeated in comments, and (3) examples are defined in R code, not comments. It is also easy to define a new syntax.

Local explanations of machine learning models describe, how features contributed to a single prediction. This package implements an explanation method based on LIME (Local Interpretable Model-agnostic Explanations, see Tulio Ribeiro, Singh, Guestrin (2016) <doi:10.1145/2939672.2939778>) in which interpretable inputs are created based on local rather than global behaviour of each original feature.

Plots contextual landmark Kaplan-Meier curves. An extension of the survminer::ggsurvplot() function that allows the specification of a landmark time and an optional label. The period before the landmark is displayed as a pooled survival curve, while curves beyond the landmark are presented according to the groups defined in the supplied survival::survfit object.